Abstract:
:An amendment to this paper has been published and can be accessed via a link at the top of the paper.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Selfslagh A,Shokur S,Campos DSF,Donati ARC,Almeida S,Yamauti SY,Coelho DB,Bouri M,Nicolelis MALdoi
10.1038/s41598-019-54834-3subject
Has Abstractpub_date
2019-12-04 00:00:00pages
18654issue
1issn
2045-2322pii
10.1038/s41598-019-54834-3journal_volume
9pub_type
已发布勘误abstract::Cortical gyrification of the brain represents the folding characteristic of the cerebral cortex. How the brain cortical gyrification changes from childhood to old age in healthy human subjects is still unclear. Additionally, studies have shown regional gyrification alterations in patients with major psychiatric disord...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-00582-1
更新日期:2017-03-30 00:00:00
abstract::Hydrogen sulfide (H2S) is involved in cancer biological processes. However, there are several controversies concerning the role of H2S in cancer development and progression. In this study, we found that the growth and migration of hepatocellular carcinoma (HCC) cells were enhanced by 10-100 μM NaHS and dose-dependentl...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-05457-z
更新日期:2017-07-11 00:00:00
abstract::High-throughput single-stranded DNA sequencing (ssDNA-seq) of cell-free DNA from plasma and other bodily fluids is a powerful method for non-invasive prenatal testing, and diagnosis of cancers and other diseases. Here, we developed a facile ssDNA-seq method, which exploits a novel template-switching activity of thermo...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-09064-w
更新日期:2017-08-21 00:00:00
abstract::An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...
journal_title:Scientific reports
pub_type: 已发布勘误
doi:10.1038/s41598-020-68522-0
更新日期:2020-07-10 00:00:00
abstract::Extracellular vesicles (EVs) such as exosomes and microvesicles serve as messengers of intercellular network, allowing exchange of cellular components between cells. EVs carry lipids, proteins, and RNAs derived from their producing cells, and have potential as biomarkers specific to cell types and even cellular states...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep33935
更新日期:2016-09-23 00:00:00
abstract::Numerous researchers have expressed concern over the emerging water scarcity issues around the globe. Economic water scarcity is severe in the developing countries; thus, the use of inexpensive wastewater treatment strategies can help minimize this issue. An abundant amount of laundry wastewater (LWW) is generated dai...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-54888-3
更新日期:2019-12-10 00:00:00
abstract::Cross-border equity and long-term debt securities portfolio investment networks are analysed from 2002 to 2012, covering the 2008 global financial crisis. They serve as network-proxies for measuring the robustness of the global financial system and the interdependence of financial markets, respectively. Two early-warn...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep03991
更新日期:2014-02-10 00:00:00
abstract::Map3k8 has been proposed as a useful target for the treatment of inflammatory diseases. We show here that during lipopolysaccharide-induced emergency granulopoiesis, Map3k8 deficiency strongly impairs the increase in circulating mature (Ly6GhighCD11b+) and immature (Ly6GlowCD11b+) neutrophils. After chimaeric bone mar...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-04538-3
更新日期:2017-07-10 00:00:00
abstract::Escherichia coli lac repressor (LacI) is a paradigmatic transcriptional factor that controls the expression of lacZYA in the lac operon. This tetrameric protein specifically binds to the O1, O2 and O3 operators of the lac operon and forms a DNA loop to repress transcription from the adjacent lac promoter. In this arti...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep19243
更新日期:2016-01-14 00:00:00
abstract::Chinese hamster ovary (CHO) cells are mainly used for recombinant protein production. However, the unstable transgene expression and lower transgene copy numbers are the major issues need to be resolved. Here, eleven internal ribosome entry site (IRES) elements from viral and cellular IRES were evaluated for foreign g...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-25049-9
更新日期:2018-04-27 00:00:00
abstract::A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper. ...
journal_title:Scientific reports
pub_type: 已发布勘误
doi:10.1038/s41598-019-43503-0
更新日期:2019-05-03 00:00:00
abstract::Congenital cataract is the most frequent inherited ocular disorder and the most leading cause of lifelong visual loss. The screening of pathogenic mutations can be very challenging in some cases, for congenital cataracts are clinically and genetically heterogeneous diseases. The aim of this study is to investigate the...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-01182-9
更新日期:2017-04-27 00:00:00
abstract::Resistant starch (RS) has been reported to reduce body fat in obese mice. However, this effect has not been demonstrated in humans. In this study, we tested the effects of RS in 19 volunteers with normal body weights. A randomized, double-blinded and crossover design clinical trial was conducted. The study subjects we...
journal_title:Scientific reports
pub_type: 杂志文章,随机对照试验
doi:10.1038/s41598-018-38216-9
更新日期:2019-03-20 00:00:00
abstract::Bruton tyrosine kinase (BTK) is a key enzyme in B-cell development whose improper regulation causes severe immunodeficiency diseases. Design of selective BTK therapeutics would benefit from improved, in-silico structural modeling of the kinase's solution ensemble. However, this remains challenging due to the immense c...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-10697-0
更新日期:2017-11-15 00:00:00
abstract::Psychopathy is a personality disorder characterised by atypical moral behaviour likely rooted in atypical affective/motivational processing, as opposed to an inability to judge the wrongness of an action. Guilt is a moral emotion believed to play a crucial role in adherence to moral and social norms, but the mechanism...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep36273
更新日期:2016-11-03 00:00:00
abstract::The concept of brain circuit disorders has been proposed for a variety of neuropsychiatric diseases, characterized by pathological disturbances of neuronal networks including changes in oscillatory signaling of re-entrant cortico-subcortical loops in the basal ganglia system. Parts of this circuitry play a pivotal rol...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-15872-x
更新日期:2017-11-14 00:00:00
abstract::Obesity-induced adipose-tissue dysfunction is a critical contributor to the pathogenesis of nonalcoholic fatty liver disease (NAFLD). B cell-activating factor (BAFF) is an adipokine related to impaired insulin sensitivity, and the serum BAFF concentration is associated with NAFLD severity. In this study, we aimed to d...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-37403-y
更新日期:2019-01-30 00:00:00
abstract::In solid state science, multifunctional materials and especially multiferroics have attracted a great deal of attention, as they open the possibility for next generation spintronic and data storage devices. Interestingly, while many of them host coexisting 3d and 4f elements, the role of the coupling between these two...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-15150-w
更新日期:2017-11-06 00:00:00
abstract::Ebola virus disease (EVD) is a contagious, severe and often lethal form of hemorrhagic fever in humans. The association of EVD outbreaks with forest clearance has been suggested previously but many aspects remained uncharacterized. We used remote sensing techniques to investigate the association between deforestation ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-14727-9
更新日期:2017-10-30 00:00:00
abstract::Sterility mosaic disease (SMD) is one of the serious production constraints that may lead to complete yield loss in pigeonpea. Three mapping populations including two recombinant inbred lines and one F2, were used for phenotyping for SMD resistance at two locations in three different years. Genotyping-by-sequencing ap...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-01535-4
更新日期:2017-05-12 00:00:00
abstract::The role of the smoothelin-like 1 (SMTNL1) protein in mediating vascular smooth muscle contractile responses to intraluminal pressure was examined in resistance vessels. Mesenteric arterioles from wild type (WT) and SMTNL1 global knock-out (KO) mice were examined with pressure myography. SMTNL1 deletion was associated...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-36564-0
更新日期:2019-01-24 00:00:00
abstract::Pre-stimulus alpha (8-12 Hz) and beta (16-20 Hz) oscillations have been frequently linked to the prediction of upcoming sensory input. Do these frequency bands serve as a neural marker of linguistic prediction as well? We hypothesized that if pre-stimulus alpha and beta oscillations index language predictions, their p...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-56600-x
更新日期:2019-12-27 00:00:00
abstract::We analysed the imaging findings of macular telangiectasia (MacTel) type 2 in Korea using spectral domain optical coherence tomography (SD-OCT) and investigated their relationship with visual acuity and clinical stages. A retrospective multicentre cross-sectional study was conducted in six tertiary hospitals in Korea ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-73803-9
更新日期:2020-10-06 00:00:00
abstract::The medicinal leech has established a long-term mutualistic association with Aeromonas veronii, a versatile bacterium which can also display free-living waterborne and fish- or human-pathogenic lifestyles. Here, we investigated the role of antibiotics in the dynamics of interaction between the leech and its gut symbio...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep17498
更新日期:2015-12-04 00:00:00
abstract::The systematics of Oriental freshwater mussels (Bivalvia: Unionidae) is poorly known. Here, we present an integrative revision of the genus Trapezoideus Simpson, 1900 to further understanding of freshwater mussel diversity in the region. We demonstrate that Trapezoideus as currently circumscribed is non-monophyletic, ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-39365-1
更新日期:2019-03-11 00:00:00
abstract::Atomistic chemical inhomogeneities are anticipated to induce dissimilarities in surface potentials, which control corrosion initiation of alloys at the atomic scale. Precise understanding of corrosion is therefore hampered by lack of definite information describing how atomistic heterogeneities regulate the process. H...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep39525
更新日期:2016-12-21 00:00:00
abstract::Since the world population is ageing, dementia is going to be a growing concern. Alzheimer's disease is the most common form of dementia. The pathogenesis of Alzheimer's disease is extensively studied, yet unknown remains. Therefore, we aimed to extract new knowledge from existing data. We analysed about 2700 upregula...
journal_title:Scientific reports
pub_type: 杂志文章,meta分析
doi:10.1038/s41598-020-64452-z
更新日期:2020-05-20 00:00:00
abstract::In the central nervous system of vertebrates, cell bodies of neurons are often assembled as nuclei or cellular layers that play specific roles as functional units. The purpose of this work was to selectively highlight such cell assemblies by magnetic resonance imaging using signals from water protons that are associat...
journal_title:Scientific reports
pub_type: 杂志文章,评审
doi:10.1038/s41598-019-41587-2
更新日期:2019-03-25 00:00:00
abstract::The development of physiologically active semiochemicals is largely limited by the labor-consuming searching process. How to screen active semiochemicals efficiently is of significance to the extension of behavior regulation in pest control. Here pharmacophore modeling and shape-based virtual screening were combined t...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep34600
更新日期:2016-10-06 00:00:00
abstract::Hepatic encephalopathy is a neuropsychiatric syndrome evolving from cerebral osmotic disturbances and oxidative/nitrosative stress. Ammonia, the main toxin of hepatic encephalopathy, triggers astrocyte senescence in an oxidative stress-dependent way. As miRNAs are critically involved in cell cycle regulation and their...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep18493
更新日期:2016-01-12 00:00:00