Nanofabrication on unconventional substrates using transferred hard masks.

abstract：:Alpha-adrenoceptor antagonists (alpha-blockers) are widely prescribed to treat lower urinary tract symptoms (LUTS) in men but fail to ameliorate LUTS sufficiently, especially the storage symptoms related to frequency, urgency and nocturia. We performed a meta-analysis of randomised controlled trials (RCTs) comparing a...

journal_title：Scientific reports

authors： Li J,Shi Q,Bai Y,Pu C,Tang Y,Yuan H,Wu Y,Wei Q,Han P

更新日期：2014-02-04 00:00:00

abstract：:Single molecule localization microscopy (SMLM) techniques allow for sub-diffraction imaging with spatial resolutions better than 10 nm reported. Much has been discussed relating to different variations of SMLM and all-inclusive microscopes can now be purchased, removing the need for in-house software or hardware devel...

journal_title：Scientific reports

authors： Whelan DR,Bell TD

更新日期：2015-01-21 00:00:00

abstract：:Hox proteins are transcription factors and key regulators of segmental identity along the anterior posterior axis across all bilaterian animals. Despite decades of research, the mechanisms by which Hox proteins select and regulate their targets remain elusive. We have carried out whole-genome ChIP-chip experiments to ...

journal_title：Scientific reports

authors： Agrawal P,Habib F,Yelagandula R,Shashidhara LS

更新日期：2011-01-01 00:00:00

abstract：:The endocannabinoid 2-arachidonoylglycerol (2-AG) functions as a retrograde signaling molecule mediating synaptic transmission and plasticity at both inhibitory and excitatory synapses. However, little is known about whether 2-AG signaling is involved in homeostatic regulation of miniature synaptic events at excitator...

journal_title：Scientific reports

authors： Song Y,Zhang J,Chen C

更新日期：2015-11-06 00:00:00

abstract：:A relevant part of embolic strokes of undetermined source (ESUS) is assumed to be cardiogenic. As shown previously, certain biomarkers of endothelial pathology are related to atrial fibrillation (AF). In this long-term follow-up study, we aimed to investigate whether these biomarkers are associated with subsequently d...

journal_title：Scientific reports

authors： Ziegler NL,Sieweke JT,Biber S,Gabriel MM,Schuppner R,Worthmann H,Martens-Lobenhoffer J,Lichtinghagen R,Bode-Böger SM,Bavendiek U,Weissenborn K,Grosse GM

更新日期：2019-12-19 00:00:00

abstract：:Sapphirinid copepods, which are marine zooplankton, exhibit tunable structural colors originating from a layered structure of guanine crystal plates. In the present study, the coloring portion of adult male of a sapphirinid copepod, Sapphirina nigromaculata, under the dorsal body surface was characterized to clarify t...

journal_title：Scientific reports

authors： Kimura T,Takasaki M,Hatai R,Nagai Y,Uematsu K,Oaki Y,Osada M,Tsuda H,Ishigure T,Toyofuku T,Shimode S,Imai H

更新日期：2020-02-10 00:00:00

abstract：:Some previous studies have indicated that valproate (VPA) might change the pharmacokinetics and enhance the effects of propofol. We evaluated whether clinical VPA therapy affected the propofol blood level, the protein-unbound free propofol level, and/or the anesthetic effects of propofol in the clinical setting. The s...

journal_title：Scientific reports

authors： Kodama M,Higuchi H,Ishii-Maruhama M,Nakano M,Honda-Wakasugi Y,Maeda S,Miyawaki T

更新日期：2020-01-31 00:00:00

abstract：:In this study, an anatase/rutile mixed-phase titanium dioxide (TiO2) hierarchical network deposited with Au nanoparticles (Au/TiO2 ARHN) was synthesized using a facile hydrothermal method followed by a simple calcination step. Such a unique structure was designed for improving the light harvest, charge transportation/...

journal_title：Scientific reports

authors： Yen YC,Chen JA,Ou S,Chen YS,Lin KJ

更新日期：2017-02-10 00:00:00

abstract：:We introduce a setup which realises a tunable engineered environment for experiments in circuit quantum electrodynamics. We illustrate this concept with the specific example of a quantum bit, qubit, in a high-quality-factor cavity which is capacitively coupled to another cavity including a resistor. The temperature of...

journal_title：Scientific reports

authors： Jones PJ,Huhtamäki JA,Salmilehto J,Tan KY,Möttönen M

更新日期：2013-01-01 00:00:00

abstract：:Escherichia coli lac repressor (LacI) is a paradigmatic transcriptional factor that controls the expression of lacZYA in the lac operon. This tetrameric protein specifically binds to the O1, O2 and O3 operators of the lac operon and forms a DNA loop to repress transcription from the adjacent lac promoter. In this arti...

journal_title：Scientific reports

authors： Fulcrand G,Dages S,Zhi X,Chapagain P,Gerstman BS,Dunlap D,Leng F

更新日期：2016-01-14 00:00:00

abstract：:Protein corona significantly affects in vivo fate of nanoparticles including biodistribution and half-life. Without manipulating the physicochemical properties of nanoparticles with considering their biointerference, attaining effective treatment protocols is impossible. For this reason, protein corona evolution and b...

journal_title：Scientific reports

authors： Tekie FSM,Hajiramezanali M,Geramifar P,Raoufi M,Dinarvand R,Soleimani M,Atyabi F

更新日期：2020-06-15 00:00:00

abstract：:Telomere DNA ends with a single-stranded 3' overhang. Long 3' overhangs may cause aberrant DNA damage responses and accelerate telomere attrition, which is associated with cancer and aging, respectively. Genetic studies have indicated several important players in preventing 5' end hyper-resection, yet detailed knowled...

journal_title：Scientific reports

authors： Runnberg R,Narayanan S,Cohn M

更新日期：2017-08-18 00:00:00

abstract：:Grafting of commercial tomato varieties and hybrids on the tomato ecotype Manduria resulted in high levels of tolerance to the infection of Sw5 resistance-breaking strains of tomato spotted wilt virus and of severe cucumber mosaic virus strains supporting hypervirulent satellite RNAs that co-determine stunting and nec...

journal_title：Scientific reports

authors： Spanò R,Ferrara M,Montemurro C,Mulè G,Gallitelli D,Mascia T

更新日期：2020-02-13 00:00:00

abstract：:Significant technical and optical advances are required for intraoperative optical coherence tomography (OCT) to be utilized during otological surgeries. Integrating OCT with surgical microscopy makes it possible to evaluate soft tissue in real-time and at a high resolution. Herein, we describe an augmented-reality, i...

journal_title：Scientific reports

authors： Lee J,Wijesinghe RE,Jeon D,Kim P,Choung YH,Jang JH,Jeon M,Kim J

更新日期：2018-11-27 00:00:00

abstract：:Glucagon-like peptide-1 (GLP-1) promotes insulin secretion from pancreatic β-cells in a glucose dependent manner. Several pathways mediate this action by rapid, kinase phosphorylation-dependent, but gene expression-independent mechanisms. Since GLP-1-induced insulin secretion requires glucose metabolism, we aimed to a...

journal_title：Scientific reports

authors： Carlessi R,Chen Y,Rowlands J,Cruzat VF,Keane KN,Egan L,Mamotte C,Stokes R,Gunton JE,Bittencourt PIH,Newsholme P

更新日期：2017-06-01 00:00:00

abstract：:Metal-silicon junctions are crucial to the operation of semiconductor devices: aggressive scaling demands low-resistive metallic terminals to replace high-doped silicon in transistors. It suggests an efficient charge injection through a low Schottky barrier between a metal and Si. Tremendous efforts invested into engi...

journal_title：Scientific reports

authors： Averyanov DV,Tokmachev AM,Karateeva CG,Karateev IA,Lobanovich EF,Prutskov GV,Parfenov OE,Taldenkov AN,Vasiliev AL,Storchak VG

更新日期：2016-05-23 00:00:00

abstract：:This paper presents the correlative imaging of collagen denaturation by nonlinear optical microscopy (NLO) and nanoscale infrared (IR) spectroscopy to obtain morphological and chemical information at different length scales. Such multiscale correlated measurements are applied to the investigation of ancient parchments...

journal_title：Scientific reports

authors： Latour G,Robinet L,Dazzi A,Portier F,Deniset-Besseau A,Schanne-Klein MC

更新日期：2016-05-19 00:00:00

abstract：:Potential benefits of carbohydrate counting for glycemic control in patients with type 1 diabetes mellitus (T1DM) remain inconclusive. Our aim is to systematically assess the efficacy of carbohydrate counting in patients with T1DM. We searched PubMed, Embase, Web of Science, Cochrane Library and the Chinese Biology Me...

journal_title：Scientific reports

authors： Fu S,Li L,Deng S,Zan L,Liu Z

更新日期：2016-11-14 00:00:00

abstract：:The prevalence of a macrophage phenotype in atherosclerotic plaque may drive its progression and/or instability. Macrophages from coronary plaques are not available, and monocyte-derived macrophages (MDMs) are usually considered as a surrogate. We compared the MDM profile obtained from coronary artery disease (CAD) pa...

journal_title：Scientific reports

authors： Eligini S,Cosentino N,Fiorelli S,Fabbiocchi F,Niccoli G,Refaat H,Camera M,Calligaris G,De Martini S,Bonomi A,Veglia F,Fracassi F,Crea F,Marenzi G,Tremoli E

更新日期：2019-06-18 00:00:00

abstract：:2,5-Dimethylfuran (DMF) is a type of attractive sustainable green energy for diesel engines that is designed to reduce soot emission. This study investigated the effect of fuel properties on the macroscopic and microscopic spray characteristics of four test blends under injection pressures of 90, 120 and 150 MPa and a...

journal_title：Scientific reports

authors： Zhang P,Su X,Chen H,Geng L,Zhao X

更新日期：2020-01-29 00:00:00

abstract：:Integrin α11β1 is a collagen-binding integrin, which is receiving increasing attention in the context of wound healing and fibrosis. Although α11β1 integrin displays similar collagen specificity to α2β1 integrin, both integrins have distinct in vivo functions. In this context, the contribution of α11 subunit cytoplasm...

journal_title：Scientific reports

authors： Erusappan P,Alam J,Lu N,Zeltz C,Gullberg D

更新日期：2019-10-25 00:00:00

abstract：:Bending light in a controllable way is desired in various applications such as beam steering, navigating and cloaking. Different from the conventional way to bend light by refractive index gradient, transformation optics or special beams through wavefront design such as Airy beams and surface plasmons, we proposed a m...

journal_title：Scientific reports

authors： Han B,Xu L,Dou Y,Xu J,Zhang G

更新日期：2015-10-29 00:00:00

abstract：:H5N1 highly pathogenic avian influenza virus (HPAIV) poses a huge threat to public health and the global economy. These viruses cause systemic infection in poultry and accidental human infection leads to severe pneumonia, associated with high mortality rates. The hemagglutinin (HA) of H5N1 HPAIV possesses multiple bas...

journal_title：Scientific reports

authors： Kajiwara N,Nomura N,Ukaji M,Yamamoto N,Kohara M,Yasui F,Sakoda Y,Kida H,Shibasaki F

更新日期：2020-10-22 00:00:00

abstract：:Glioblastomas are highly malignant brain tumors. Knowledge of growth rates and growth patterns is useful for understanding tumor biology and planning treatment logistics. Based on untreated human glioblastoma data collected in Trondheim, Norway, we first fit the average growth to a Gompertz curve, then find a best fit...

journal_title：Scientific reports

authors： Ma Z,Niu B,Phan TA,Stensjøen AL,Ene C,Woodiwiss T,Wang T,Maini PK,Holland EC,Tian JP

更新日期：2020-04-20 00:00:00

abstract：:Green fluorescent protein (GFP) is one of the most used reporter genes. We have used next-generation sequencing (NGS) to analyse the genetic diversity of a recombinant influenza A virus that expresses GFP and found a remarkable coverage dip in the GFP coding sequence. This coverage dip was present when virus-derived R...

journal_title：Scientific reports

authors： Van den Hoecke S,Verhelst J,Saelens X

更新日期：2016-05-19 00:00:00

abstract：:Congenital ptosis may be associated with abnormalities of visual development and function, including amblyopia, strabismus and refractive errors. However, the prevalence estimates of these abnormalities vary widely. We performed a systematic review and meta-analysis to estimate the prevalence of amblyopia, strabismus ...

journal_title：Scientific reports

authors： Wang Y,Xu Y,Liu X,Lou L,Ye J

更新日期：2018-05-29 00:00:00

abstract：:Schizophrenia is a common and severe mental disorder arising from complex gene-environment interactions affecting brain development and functioning. While a consensus on the neuroanatomical correlates of schizophrenia is emerging, much of its fundamental pathobiology remains unknown. In this study, we explore brain mo...

journal_title：Scientific reports

authors： Qvist P,Eskildsen SF,Hansen B,Baragji M,Ringgaard S,Roovers J,Paternoster V,Molgaard S,Corydon TJ,Stødkilde-Jørgensen H,Glerup S,Mors O,Wegener G,Nyengaard JR,Børglum AD,Christensen JH

更新日期：2018-11-07 00:00:00

abstract：:Medulloblastoma is a malignant pediatric tumor that arises from neural progenitors in the cerebellum. Despite a five-year survival rate of ~70%, nearly all patients incur adverse side effects from current treatment strategies that drastically impact quality of life. Roughly one-third of medulloblastoma are driven by a...

journal_title：Scientific reports

authors： Robinson MH,Maximov V,Lallani S,Farooq H,Taylor MD,Read RD,Kenney AM

更新日期：2019-09-20 00:00:00

abstract：:Maximal rate of heart rate (HR) increase (rHRI) as a measure of HR acceleration during the transition from rest to exercise, or during an increase in workload, tracks exercise performance. rHRI assessed at relative rather than absolute workloads may track performance better, and a field test would increase applicabili...

journal_title：Scientific reports

authors： Bellenger CR,Thomson RL,Robertson EY,Davison K,Nelson MJ,Karavirta L,Buckley JD

更新日期：2020-09-03 00:00:00

abstract：:Bispecific killer cells engagers (BiKEs) which can bind to natural killer (NK) cells through the activating receptor CD16A and guide them to cells expressing the HIV-1 envelope glycoprotein (Env) are a promising new weapon for elimination of infected cells and eradication of the virus. Here we report the design, gener...

journal_title：Scientific reports

authors： Li W,Wu Y,Kong D,Yang H,Wang Y,Shao J,Feng Y,Chen W,Ma L,Ying T,Dimitrov DS

更新日期：2017-08-22 00:00:00