Open chromatin dynamics in prosensory cells of the embryonic mouse cochlea.

abstract：:Reliable P wave detection is necessary for accurate and automatic electrocardiogram (ECG) analysis. Currently, methods for P wave detection in physiological conditions are well-described and efficient. However, methods for P wave detection during pathology are not generally found in the literature, or their performanc...

journal_title：Scientific reports

authors： Maršánová L,Němcová A,Smíšek R,Vítek M,Smital L

更新日期：2019-12-13 00:00:00

abstract：:We have previously shown that OX40L/OX40 interaction is critical for TCR-independent selective proliferation of Foxp3+ Tregs, but not Foxp3- effector T-cells (Teff), when CD4+ T-cells are co-cultured with GM-CSF derived bone marrow dendritic cells (G-BMDCs). Events downstream of OX40L/OX40 interaction in Tregs respons...

journal_title：Scientific reports

authors： Alharshawi K,Marinelarena A,Kumar P,El-Sayed O,Bhattacharya P,Sun Z,Epstein AL,Maker AV,Prabhakar BS

更新日期：2017-07-26 00:00:00

abstract：:State-of-art quantum key distribution (QKD) systems are performed with several GHz pulse rates, meanwhile privacy amplification (PA) with large scale inputs has to be performed to generate the final secure keys with quantified security. In this paper, we propose a fast Fourier transform (FFT) enhanced high-speed and l...

journal_title：Scientific reports

authors： Tang BY,Liu B,Zhai YP,Wu CQ,Yu WR

更新日期：2019-10-31 00:00:00

abstract：:Acoustic manipulation by an ultrasonic phased array provides an entirely new approach to processes such as coalescence, mixing, separation, and evaporation occurring in the generation of new materials, physical property measurement, the biomedical industry, etc. However, to date, ultrasonic phased arrays have not been...

journal_title：Scientific reports

authors： Watanabe A,Hasegawa K,Abe Y

更新日期：2018-07-05 00:00:00

abstract：:Adding fluoride into bioactive glasses leads to fluorapatite formation and a decrease in glass transition temperature. Recently, chloride has been introduced into glasses as an alternative to fluoride. The presence of the large chloride ion lowers glass crystallisation tendency and increases glass molar volume, which ...

journal_title：Scientific reports

authors： Chen X,Chen X,Pedone A,Apperley D,Hill RG,Karpukhina N

更新日期：2018-01-22 00:00:00

abstract：:An initial study of processing bioresorbable polycaprolactone (PCL) through material jetting was conducted using a Fujifilm Dimatix DMP-2830 material printer. The aim of this work was to investigate a potential solvent based method of jetting polycaprolactone. Several solvents were used to prepare a PCL solvent based ...

journal_title：Scientific reports

authors： He Y,Wildman RD,Tuck CJ,Christie SD,Edmondson S

更新日期：2016-02-12 00:00:00

abstract：:Nesfatin-1, a satiety molecule processed from nucleobindin2 (NUCB2), is implicated in visceral hypersensitivity in rats and colocalized with 5-hydroxytryptamine (5-HT) in the dorsal raphe nucleus (DRN). Maternal separation (MS) in rats contributes to visceral hypersensitivity via elevated expression of 5-HT in the DRN...

journal_title：Scientific reports

authors： Zhang HA,Sang N,Ge X,Huang Q,Li XL,Sha J

更新日期：2018-06-19 00:00:00

abstract：:In our experiment, it was observed that the emission of direct-gap band in germanium with Ge-GeSn layers on one-dimensional (1D) structure. The results of experiment and calculation demonstrate that the uniaxial tensile strain in the (111) and (110) direction can efficiently transform Ge to a direct bandgap material w...

journal_title：Scientific reports

authors： Huang ZM,Huang WQ,Liu SR,Dong TG,Wang G,Wu XK,Qin CJ

更新日期：2016-04-21 00:00:00

abstract：:Increasing structural complexity at nanoscale can permit superior control over photophysical properties in the precursor-derived semiconductors. We demonstrate here the synthesis of silicon carbonitride (SiCN)/boron nitride (BN) nanocomposites via a polymer precursor route wherein the cobalt polyamine complexes used a...

journal_title：Scientific reports

authors： Zhang Q,Jia D,Yang Z,Cai D,Laine RM,Li Q,Zhou Y

更新日期：2017-01-13 00:00:00

abstract：:Radix Astragali is commonly used in traditional Chinese medicine, and its quality is closely related to ecological factors, such as climate and soil, in the production area. To provide high-quality Radix Astragali to Chinese and foreign markets, we used maximum entropy model and statistical analysis method, combined w...

journal_title：Scientific reports

authors： Yang M,Li Z,Liu L,Bo A,Zhang C,Li M

更新日期：2020-07-27 00:00:00

abstract：:Preterm infants are susceptible to inflammation-induced white matter injury but the exposures that lead to this are uncertain. Histologic chorioamnionitis (HCA) reflects intrauterine inflammation, can trigger a fetal inflammatory response, and is closely associated with premature birth. In a cohort of 90 preterm infan...

journal_title：Scientific reports

authors： Anblagan D,Pataky R,Evans MJ,Telford EJ,Serag A,Sparrow S,Piyasena C,Semple SI,Wilkinson AG,Bastin ME,Boardman JP

更新日期：2016-12-01 00:00:00

abstract：:Transthyretin (TTR) is a blood and cerebrospinal fluid transporter of thyroxine and retinol. Gene expression profiling revealed an elevation of Ttr expression in the dorsomedial hypothalamus (DMH) of rats with exercise-induced anorexia, implying that central TTR may also play a functional role in modulating food intak...

journal_title：Scientific reports

authors： Zheng F,Kim YJ,Moran TH,Li H,Bi S

更新日期：2016-04-07 00:00:00

abstract：:We discuss a scheme to retrieve transient conformational molecular structure information using photoelectron angular distributions (PADs) that have averaged over partial alignments of isolated molecules. The photoelectron is pulled out from a localized inner-shell molecular orbital by an X-ray photon. We show that a t...

journal_title：Scientific reports

authors： Wang X,Le AT,Yu C,Lucchese RR,Lin CD

更新日期：2016-03-30 00:00:00

abstract：:The new π-extended redox-active ligand with both TTF and triazole units, 6-(4,5-bis(propylthio)-1,3-dithiol-2-ylidene)-1H-[1,3]dithiolo[4',5':4,5]benzo [1,2-d] [1-3]triazole, has been successfully prepared. Based on the versatile ligand and Cu(tta)2 precursors (tta(-) = 4,4,4-trifluoro-1-(thiophen-2-yl)butane-1,3-dion...

journal_title：Scientific reports

authors： Cui L,Geng YF,Leong CF,Ma Q,D'Alessandro DM,Deng K,Zeng QD,Zuo JL

更新日期：2016-05-06 00:00:00

abstract：:Over the last 5-10 years, optical coherence tomography (OCT) and atomic force microscopy (AFM) have been individually applied to monitor the morphological and mechanical properties of various single-species biofilms respectively. This investigation looked to combine OCT and AFM as a multi-scale approach to understand ...

journal_title：Scientific reports

authors： Pattem J,Davrandi M,Aguayo S,Allan E,Spratt D,Bozec L

更新日期：2018-04-09 00:00:00

abstract：:Endothelin-1 (ET-1), a vasoconstrictor, has recently been used to induce focal ischemia in rodents and marmoset monkeys. The rhesus monkey, however, has numerous advantages to the rodent and marmoset that make it a superior and irreplaceable animal model for studying stroke in the brain. In the present study, after ma...

journal_title：Scientific reports

authors： Dai P,Huang H,Zhang L,He J,Zhao X,Yang F,Zhao N,Yang J,Ge L,Lin Y,Yu H,Wang J

更新日期：2017-03-30 00:00:00

abstract：:The repeated measurements of heart rate variability (HRV) is more relevant than a single HRV measurement in predicting patient prognosis but is less addressed previously. This prospective study aimed to investigate the association between repeated measurements of HRV and long-term mortality in chronic hemodialysis pat...

journal_title：Scientific reports

authors： Chang YM,Huang YT,Chen IL,Yang CL,Leu SC,Su HL,Kao JL,Tsai SC,Jhen RN,Shiao CC

更新日期：2020-01-21 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Wada Y,Nithichanon A,Nobusawa E,Moise L,Martin WD,Yamamoto N,Terahara K,Hagiwara H,Odagiri T,Tashiro M,Lertmemongkolchai G,Takeyama H,De Groot AS,Ato M,Takahashi Y

更新日期：2019-10-08 00:00:00

abstract：:Polymorphisms contribute to inter-individual differences and show a promising predictive role for chemotherapy-related toxicity in colon cancer (CC). TOSCA is a multicentre, randomized, non-inferiority, phase III study conducted in high-risk stage II/stage III CC patients treated with 6 vs 3 months of FOLFOX-4 or XELO...

journal_title：Scientific reports

authors： Ruzzo A,Graziano F,Galli F,Galli F,Rulli E,Lonardi S,Ronzoni M,Massidda B,Zagonel V,Pella N,Mucciarini C,Labianca R,Ionta MT,Bagaloni I,Veltri E,Sozzi P,Barni S,Ricci V,Foltran L,Nicolini M,Biondi E,Bramati A,

更新日期：2019-08-08 00:00:00

abstract：:Photoactivated localization microscopy (PALM) is a super-resolution imaging technique based on the detection and subsequent localization of single fluorescent molecules. PALM is therefore a powerful tool in resolving structures and putative interactions of biomolecules at the ultimate analytical detection limit. Howev...

journal_title：Scientific reports

authors： Vangindertael J,Beets I,Rocha S,Dedecker P,Schoofs L,Vanhoorelbeke K,Hofkens J,Mizuno H

更新日期：2015-09-01 00:00:00

abstract：:Printing techniques are becoming increasingly prevalent in modern manufacturing. However, its biggest drawback is the limit in printing resolution. In this paper, we present solvodynamic printing as a novel printing system which aims to improve print resolution by incorporating an additional immiscible carrier solvent...

journal_title：Scientific reports

authors： Liu WC,Watt AAR

更新日期：2019-07-24 00:00:00

abstract：:Exercise physiology is different in males and females. Females are poorly studied due to the complexity of the estrous cycle and this bias has created an exercise sex gap. Here, we evaluated the impact of sexual dimorphism and of the estrous cycle on muscle strength and running power of C57BL/6 mice. Like men, male mi...

journal_title：Scientific reports

authors： Aguiar AS Jr,Speck AE,Amaral IM,Canas PM,Cunha RA

更新日期：2018-07-16 00:00:00

abstract：:The aim is to design a patient-specific instrument (PSI) for multilevel cervical pedicle screw placement from C2 to C7, as well as verifying reliability and reproducibility. Computed tomography (CT) scans were obtained from 7 cadaveric cervical spines. Using Mimics software, semiautomatic segmentation was performed fo...

journal_title：Scientific reports

authors： Sallent A,Ramírez M,Catalá J,Rodríguez-Baeza A,Bagó J,de Albert M,Vélez R

更新日期：2019-10-30 00:00:00

abstract：:Hominin dietary specialization is crucial to understanding the evolutionary changes of craniofacial biomechanics and the interaction of food processing methods' effects on teeth. However, the diet-related dental wear processes of the earliest European hominins remain unknown because most of the academic attention has ...

journal_title：Scientific reports

authors： Pérez-Pérez A,Lozano M,Romero A,Martínez LM,Galbany J,Pinilla B,Estebaranz-Sánchez F,Bermúdez de Castro JM,Carbonell E,Arsuaga JL

更新日期：2017-02-27 00:00:00

abstract：:The number of osteoarthritis patients is increasing with the rise in the number of elderly people in developed countries. Osteoarthritis, which causes joint pain and deformity leading to loss of activities of daily living, is often treated surgically. Here we show that mechanical stress promotes accumulation of reacti...

journal_title：Scientific reports

authors： Kaneko Y,Tanigawa N,Sato Y,Kobayashi T,Nakamura S,Ito E,Soma T,Miyamoto K,Kobayashi S,Harato K,Matsumoto M,Nakamura M,Niki Y,Miyamoto T

更新日期：2019-12-10 00:00:00

abstract：:The CRISPR-Cas9 system has a potential for wide application in organisms that particularly present low homologous integration rates. In this study, we developed three different methods using this system to replace a gene through homology-directed repair in the plant pathogenic fungus Colletotrichum sansevieriae, which...

journal_title：Scientific reports

authors： Nakamura M,Okamura Y,Iwai H

更新日期：2019-12-12 00:00:00

abstract：:We show that through the wave energy conserved and reversible process of coherent interactions of scalar waves in a multi-channel system joint by a common junction, it is possible to generate outgoing waves only in certain channels by controlling the incoming waves. We refer to such processes as coherent perfect chann...

journal_title：Scientific reports

authors： Zhang X,Meng C,Yang Z

更新日期：2017-10-24 00:00:00

abstract：:The prognostic relevance of strokes in different locations is debated. For example, insular strokes have been associated with increased mortality, but this association could reflect their greater severity. In two independent cohorts of patients with supratentorial ischemic stroke (n = 90 and 105), we studied the progn...

journal_title：Scientific reports

authors： Laredo C,Zhao Y,Rudilosso S,Renú A,Pariente JC,Chamorro Á,Urra X

更新日期：2018-06-22 00:00:00

abstract：:Clouds play a major role in the climate system, but large uncertainties remain about their decadal variations. Here we report a widespread decrease in cloud cover since the 1970 s over the Mediterranean region, in particular during the 1970 s-1980 s, especially in the central and eastern areas and during springtime. C...

journal_title：Scientific reports

authors： Sanchez-Lorenzo A,Enriquez-Alonso A,Calbó J,González JA,Wild M,Folini D,Norris JR,Vicente-Serrano SM

更新日期：2017-02-02 00:00:00

abstract：:This study investigated the effects of 4 aeration levels (varied by injection of air to the soil through subsurface irrigation lines) at two subsurface irrigation line depths (15 and 40 cm) on plant growth, yield and nutritional quality of greenhouse tomato. In all experiments, fruit number, width and length, yield, v...

journal_title：Scientific reports

authors： Li Y,Niu W,Dyck M,Wang J,Zou X

更新日期：2016-12-20 00:00:00