Publisher Correction: A humanized mouse model identifies key amino acids for low immunogenicity of H7N9 vaccines.

abstract：:Since domestication, a large number of livestock breeds adapted to local conditions have been created by natural and artificial selection, representing one of the most powerful ways in which human groups have constructed niches to meet their need. Although many authors have described local breeds as the result of cult...

journal_title：Scientific reports

authors： Colino-Rabanal VJ,Rodríguez-Díaz R,Blanco-Villegas MJ,Peris SJ,Lizana M

更新日期：2018-04-24 00:00:00

abstract：:Solving river engineering problems typically requires river flow characterization, including the prediction of flow depth, flow velocity, and flood extent. Hydraulic models use governing equations of the flow in motion (conservation of mass and momentum principles) to predict the flow characteristics. However, solving...

journal_title：Scientific reports

authors： Hosseiny H,Nazari F,Smith V,Nataraj C

更新日期：2020-05-19 00:00:00

abstract：:Information on the bioavailability and -accessibility of subsoil phosphorus (P) and how soil moisture affects its utilization by plants is scarce. The current study examined whether and to which degree wheat acquires P from subsoil allocated hydroxyapatite and how this could be affected by soil moisture. We investigat...

journal_title：Scientific reports

authors： Wolff J,Hofmann D,Koch M,Bol R,Schnepf A,Amelung W

更新日期：2020-10-13 00:00:00

abstract：:ADP-ribosyltransferases (ARTs) modify proteins with single units or polymers of ADP-ribose to regulate DNA repair. However, the substrates for these enzymes are ill-defined. For example, although histones are modified by ARTs, the sites on these proteins ADP-ribosylated following DNA damage and the ARTs that catalyse ...

journal_title：Scientific reports

authors： Rakhimova A,Ura S,Hsu DW,Wang HY,Pears CJ,Lakin ND

更新日期：2017-03-02 00:00:00

abstract：:Metagenomics brings in new discoveries and insights into the uncultured microbial world. One fundamental task in metagenomics analysis is to determine the taxonomy of raw sequence fragments. Modern sequencing technologies produce relatively short fragments and greatly increase the number of fragments, and thus make th...

journal_title：Scientific reports

authors： Jiang Y,Wang J,Xia D,Yu G

更新日期：2017-08-25 00:00:00

abstract：:Glycolipids had received increasing attention because of their uses in various industries like cosmetics, pharmaceuticals, food and machinery manufacture. Microalgae were competitive organisms to accumulate metabolic substance. However, using microalgae to produce glycolipid was rare at present. In this study, glycoli...

journal_title：Scientific reports

authors： Wang X,Shen Z,Miao X

更新日期：2016-07-21 00:00:00

abstract：:A variety of post-translational modifications of Plasmodium falciparum proteins, including phosphorylation and ubiquitination, are shown to have key regulatory roles during parasite development. NEDD8 is a ubiquitin-like modifier of cullin-RING E3 ubiquitin ligases, which regulates diverse cellular processes. Although...

journal_title：Scientific reports

authors： Bhattacharjee M,Adhikari N,Sudhakar R,Rizvi Z,Das D,Palanimurugan R,Sijwali PS

更新日期：2020-11-19 00:00:00

abstract：:Transgenic sheep can be used to achieve genetic improvements in breeds and as an important large-animal model for biomedical research. In this study, we generated a TALEN plasmid specific for ovine MSTN and transfected it into fetal fibroblast cells of STH sheep. MSTN biallelic-KO somatic cells were selected as nuclea...

journal_title：Scientific reports

authors： Li H,Wang G,Hao Z,Zhang G,Qing Y,Liu S,Qing L,Pan W,Chen L,Liu G,Zhao R,Jia B,Zeng L,Guo J,Zhao L,Zhao H,Lv C,Xu K,Cheng W,Li H,Zhao HY,Wang W,Wei HJ

更新日期：2016-09-22 00:00:00

abstract：:Autophagy is known to be implicated in the pathogenesis of Sjögren syndrome (SS), but evidences are limited. We aimed to examine the levels of autophagy markers in tear film and conjunctival epithelial cells from SS dry eye patients, and analyze their correlations with clinical features. Patients with SS dry eye exhib...

journal_title：Scientific reports

authors： Byun YS,Lee HJ,Shin S,Chung SH

更新日期：2017-12-08 00:00:00

abstract：:In this study, genomic DNA was screened from Halobacillus andaensis NEAU-ST10-40T by selection in Escherichia coli KNabc lacking three major Na+/H+ antiporters. One gene designated upf0118 exhibiting Na+(Li+)/H+ antiport activity was finally cloned. Protein alignment showed that UPF0118 shares the highest identity of ...

journal_title：Scientific reports

authors： Dong P,Wang L,Song N,Yang L,Chen J,Yan M,Chen H,Zhang R,Li J,Abdel-Motaal H,Jiang J

更新日期：2017-04-04 00:00:00

abstract：:Defects of vitamin B6 metabolism are responsible for severe neurological disorders, such as pyridoxamine 5'-phosphate oxidase deficiency (PNPOD; OMIM: 610090), an autosomal recessive inborn error of metabolism that usually manifests with neonatal-onset severe seizures and subsequent encephalopathy. At present, 27 path...

journal_title：Scientific reports

authors： Barile A,Nogués I,di Salvo ML,Bunik V,Contestabile R,Tramonti A

更新日期：2020-08-12 00:00:00

abstract：:Evidence on the association between dietary fiber intake and pancreatic cancer risk has been controversial. Therefore, we carried out this meta-analysis to summarize available evidence from epidemiologic studies on this point. Relevant studies were identified by searching PubMed, Embase and Web of Science databases as...

journal_title：Scientific reports

authors： Wang CH,Qiao C,Wang RC,Zhou WP

更新日期：2015-06-02 00:00:00

abstract：:Risks threatening modern societies form an intricately interconnected network that often underlies crisis situations. Yet, little is known about how risk materializations in distinct domains influence each other. Here we present an approach in which expert assessments of likelihoods and influence of risks underlie a q...

journal_title：Scientific reports

authors： Szymanski BK,Lin X,Asztalos A,Sreenivasan S

更新日期：2015-06-18 00:00:00

abstract：:Cell-to-cell heterogeneity is driven by stochasticity in intracellular reactions and the population dynamics. While these sources are usually studied separately, we develop an agent-based framework that accounts for both factors while tracking every single cell of a growing population. Apart from the common intrinsic ...

journal_title：Scientific reports

authors： Thomas P

更新日期：2019-01-24 00:00:00

abstract：:Bacterial vaginosis (BV) is associated with HIV acquisition and adverse pregnancy outcomes. Recurrence after metronidazole treatment is high. HIV-negative, non-pregnant Rwandan BV patients were randomized to four groups (n = 17/group) after seven-day oral metronidazole treatment: behavioral counseling only (control), ...

journal_title：Scientific reports

authors： van de Wijgert JHHM,Verwijs MC,Agaba SK,Bronowski C,Mwambarangwe L,Uwineza M,Lievens E,Nivoliez A,Ravel J,Darby AC

更新日期：2020-03-03 00:00:00

abstract：:The aim of this systematic review was taken to investigate the efficacy and safety of docetaxel plus thalidomide vs. docetaxel alone for treating androgen-independent prostate cancer (AIPC). Data were collected from different databases independently by three researchers according to the pre-defined inclusion and exclu...

journal_title：Scientific reports

authors： Chen L,Qiu X,Wang R,Xie X

更新日期：2014-04-28 00:00:00

abstract：:Insulin-like growth factor-I (IGF-I) is involved in the maturation and maintenance of neurons, and impaired IGF-I signaling has been shown to play a role in various neurological diseases including stroke. The aim of the present study was to investigate the efficacy of an optimized IGF-I variant by adding a 40 kDa poly...

journal_title：Scientific reports

authors： Parker K,Berretta A,Saenger S,Sivaramakrishnan M,Shirley SA,Metzger F,Clarkson AN

更新日期：2017-03-21 00:00:00

abstract：:To achieve six degree-of-freedom autonomous navigation of an inboard spacecraft, a novel algorithm called iterative closest imaging point (ICIP) is proposed, which deals with the pose estimation problem of a vision navigation system (VNS). This paper introduces the basics of the ICIP algorithm, including mathematical ...

journal_title：Scientific reports

authors： Shi S,You Z,Zhao K,Wang Z,Ouyang C,Cao Y

更新日期：2017-12-12 00:00:00

abstract：:The function of Forkhead box O 1 (FOXO1) and pSerine256-FOXO1 immunostaining in esophageal cancer is unclear. To clarify the prognostic role of nuclear FOXO1 and cytoplasmic pSerine256-FOXO1 immunostaining, a tissue microarray containing more than 600 esophageal cancers was analyzed. In non-neoplastic esophageal mucos...

journal_title：Scientific reports

authors： Grupp K,Uzunoglu FG,Melling N,Hofmann B,El Gammal AT,Grotelüschen R,Heumann A,Bellon E,Reeh M,Wolters-Eisfeld G,Ghabdan T,Nentwich M,Bachmann K,Bockhorn M,Bogoevski D,Izbicki JR,Kutup A

更新日期：2018-11-26 00:00:00

abstract：:The activation and growth of tumour-initiating cells with stem-like properties in distant organs characterize colorectal cancer (CRC) growth and metastasis. Thus, inhibition of colon cancer stem cell (CCSC) growth holds promise for CRC growth and metastasis prevention. We and others have shown that farnesyl dimethyl c...

journal_title：Scientific reports

authors： Husain K,Coppola D,Yang CS,Malafa MP

更新日期：2021-01-26 00:00:00

abstract：:Obesity causes low-grade inflammation that is involved in male infertility. Interleukin 1 beta (IL1β) plays an important role in this process. A high-fat diet (HFD) is the most common cause of obesity. However, the effect of a HFD on IL1β and its consequence in reproduction remain unclear. We established a HFD model i...

journal_title：Scientific reports

authors： Zhang J,Li K,Yuan M,Zhang J,Huang G,Ao J,Tan H,Li Y,Gong D,Li J,Kang L,An N,Li F,Lin P,Huang L

更新日期：2017-04-03 00:00:00

abstract：:Rejuvenation is the configurational excitation of amorphous materials and is one of the more promising approaches for improving the deformability of amorphous metals that usually exhibit macroscopic brittle fracture modes. Here, we propose a method to control the level of rejuvenation through systematic thermal proces...

journal_title：Scientific reports

authors： Wakeda M,Saida J,Li J,Ogata S

更新日期：2015-05-26 00:00:00

abstract：:The colour of oyster shells is a very diverse characteristic morphotype, forming intriguing vivid patterns both on the inside and outside of the shell. In the present study, we have identified for the first time, the presence of several porphyrins as constituents of the shell pigmentation of the Crassostrea gigas oyst...

journal_title：Scientific reports

authors： Bonnard M,Cantel S,Boury B,Parrot I

更新日期：2020-07-22 00:00:00

abstract：:We report the observation of replica symmetry breaking (RSB) in a weakly scattering optofluidic random laser (ORL). Coherent random lasing is indicated by the presence of narrow peaks rising out of the spectral background. This coherence helps to identify a random laser threshold, which is expected to be gradual with ...

journal_title：Scientific reports

authors： Sarkar A,Bhaktha BNS,Andreasen J

更新日期：2020-02-14 00:00:00

abstract：:Organ transplantation remains the most effective treatment for patients with late stage organ failure. Transgenic pigs provide an alternative organ donor source to the limited availability of human organs. However, cellular rejection still remains to be the obstacle for xenotransplantation. Superior to other methods, ...

journal_title：Scientific reports

authors： Li M,Eckl J,Geiger C,Schendel DJ,Pohla H

更新日期：2017-06-21 00:00:00

abstract：:This is the first pharmacological characterisation of a neuropeptide G protein-coupled receptor (GPCR) in a crustacean. We cloned the ORF of the red pigment-concentrating hormone from a German strain of Daphnia pulex (Dappu-RPCH), as well as that of the cognate receptor (Dappu-RPCHR). Dappu-RPCHR has the hallmarks of ...

journal_title：Scientific reports

authors： Marco HG,Verlinden H,Vanden Broeck J,Gäde G

更新日期：2017-07-31 00:00:00

abstract：:For understanding the quantitative effect of nonhydrostatic stress on properties of material, the crystal structure and Raman spectra of 3C-SiC under hydrostatic and nonhydrostatic stress were calculated using a first-principles method. The results show that the lattice constants (a, b, and c) under nonhydrostatic str...

journal_title：Scientific reports

authors： Lei L,Li Y,Hong L,Ying L,Chun-Qiang Z,Long-Xing Y,Gui-Ping L

更新日期：2018-07-26 00:00:00

abstract：:Peptides derived from the N-terminal heptad repeat (NHR) of HIV-1 gp41 can be potent inhibitors against viral entry when presented in a nonaggregating trimeric coiled-coil conformation via the introduction of exogenous trimerization motifs and intermolecular disulfide bonds. We recently discovered that crosslinking is...

journal_title：Scientific reports

authors： Wang C,Li X,Yu F,Lu L,Jiang X,Xu X,Wang H,Lai W,Zhang T,Zhang Z,Ye L,Jiang S,Liu K

更新日期：2016-08-26 00:00:00

abstract：:This paper proposes new ways to assess handwriting, a critical skill in any child's school journey. Traditionally, a pen and paper test called the BHK test (Concise Evaluation Scale for Children's Handwriting) is used to assess children's handwriting in French-speaking countries. Any child with a BHK score above a cer...

journal_title：Scientific reports

authors： Asselborn T,Chapatte M,Dillenbourg P

更新日期：2020-02-21 00:00:00

abstract：:Reef sharks are vulnerable predators experiencing severe population declines mainly due to overexploitation. However, beyond direct exploitation, human activities can produce indirect or sub-lethal effects such as behavioral alterations. Such alterations are well known for terrestrial fauna but poorly documented for m...

journal_title：Scientific reports

authors： Juhel JB,Vigliola L,Wantiez L,Letessier TB,Meeuwig JJ,Mouillot D

更新日期：2019-02-27 00:00:00