A UPF0118 family protein with uncharacterized function from the moderate halophile Halobacillus andaensis represents a novel class of Na+(Li+)/H+ antiporter.

abstract：:Hepatitis C virus (HCV) has long been observed to take advantage of the host mitochondria to support viral replication and assembly. The HCV core protein has been implicated to fragment host mitochondria. In this report, we have discovered that the non-structural protein 5A (NS5A) plays an instructive role in attachin...

journal_title：Scientific reports

authors： Siu GK,Zhou F,Yu MK,Zhang L,Wang T,Liang Y,Chen Y,Chan HC,Yu S

更新日期：2016-03-24 00:00:00

abstract：:Although 3,5,3'-triiodothyronine (T3) is considered to be the primary bioactive thyroid hormone (TH) due to its high affinity for TH nuclear receptors (TRs), new data suggest that 3,5-diiodothyronine (T2) can also regulate transcriptional networks. To determine the functional relevance of these bioactive THs, RNA-seq ...

journal_title：Scientific reports

authors： Olvera A,Martyniuk CJ,Buisine N,Jiménez-Jacinto V,Sanchez-Flores A,Sachs LM,Orozco A

更新日期：2017-11-08 00:00:00

abstract：:The objective of this study was to determine the prevalence of sexual dysfunction in Saudi and non-Saudi female health care providers in Jeddah, Saudi Arabia. One -hundred twenty (60 Saudi and 60 non-Saudi) sexually active female health care professionals in Jeddah, Saudi Arabia, were anonymously surveyed using the En...

journal_title：Scientific reports

authors： Rouzi AA,Sahly N,Sawan D,Kafy S,Alzaban F

更新日期：2015-01-20 00:00:00

abstract：:Familial breast cancer is estimated to account for 15-20% of all cases of breast cancer. Surveillance for familial breast cancer is well-established world-wide. However, this service does not exist in Jordan, due to the scarcity of information with regard to the genetic profiling of these patients, and therefore lack ...

journal_title：Scientific reports

authors： Abu-Helalah M,Azab B,Mubaidin R,Ali D,Jafar H,Alshraideh H,Drou N,Awidi A

更新日期：2020-10-16 00:00:00

abstract：:CD4(+)CD25(+) T cells are critical for maintenance of immunologic self-tolerance. We measured the number of CD4(+)CD25(+) cells in the patients with primary malignant hypertension related kidney injury, to explore the molecular pathogenesis of this disease. We selected 30 patients with primary malignant hypertension r...

journal_title：Scientific reports

authors： Huang H,Luo Y,Liang Y,Long X,Peng Y,Liu Z,Wen X,Jia M,Tian R,Bai C,Li C,He F,Lin Q,Wang X,Dong X

更新日期：2016-06-09 00:00:00

abstract：:Predicting the occurrence of ventricular tachyarrhythmia (VTA) in advance is a matter of utmost importance for saving the lives of cardiac arrhythmia patients. Machine learning algorithms have been used to predict the occurrence of imminent VTA. In this study, we used a one-dimensional convolutional neural network (1-...

journal_title：Scientific reports

authors： Taye GT,Hwang HJ,Lim KM

更新日期：2020-04-21 00:00:00

abstract：:A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper. ...

journal_title：Scientific reports

authors： Safra L,Ioannou C,Amsellem F,Delorme R,Chevallier C

更新日期：2018-12-21 00:00:00

abstract：:Quantum physics is undoubtedly the most successful theory of the microscopic world, yet the complexities which arise in applying it even to simple atomic and molecular systems render the description of basic collision probabilities a formidable task. For this reason, approximations are often employed, the validity of ...

journal_title：Scientific reports

authors： Laricchia G,Van Reeth P,Fayer SE,Brawley SJ,Kadokura R,Loreti A,Shipman M

更新日期：2018-10-10 00:00:00

abstract：:The chemokine CCL3 is frequently overexpressed in malignancies and overexpression leads to microenvironmental dysfunction. In murine models of chronic myelogenous leukemia (CML), CCL3 is critical for the maintenance of a leukemia stem cell population, and leukemia progression. With CCL3 implicated as a potentially via...

journal_title：Scientific reports

authors： Staversky RJ,Byun DK,Georger MA,Zaffuto BJ,Goodman A,Becker MW,Calvi LM,Frisch BJ

更新日期：2018-10-02 00:00:00

abstract：:Concurrent chemoradiation therapy (CCRT) is the treatment of choice for locally advanced non-small cell lung cancer (LA-NSCLC). Several clinical trials that combine programmed cell death 1 (PD-1) axis inhibitors with radiotherapy are in development for patients with LA-NSCLC. However, the effect of CCRT on programmed ...

journal_title：Scientific reports

authors： Fujimoto D,Uehara K,Sato Y,Sakanoue I,Ito M,Teraoka S,Nagata K,Nakagawa A,Kosaka Y,Otsuka K,Imai Y,Hamakawa H,Takahashi Y,Kokubo M,Tomii K

更新日期：2017-09-12 00:00:00

abstract：:Adolescence is a critical stage of development and has an important influence on energy balance-related behaviours (EBRBs). When adolescents are associated with obesity it can lead to increased cardiometabolic risk. Here we assess if EBRBs adopted by adolescents included in a subsample are associated with markers of t...

journal_title：Scientific reports

authors： Forkert ECO,Moraes ACF,Carvalho HB,Manios Y,Widhalm K,González-Gross M,Gutierrez A,Kafatos A,Censi L,De Henauw S,Moreno LA

更新日期：2019-04-23 00:00:00

abstract：:The precise clinicopathologic significance of myeloid differentiation primary response gene (MYD88) L265P mutation in diffuse large B-cell lymphomas (DLBCLs) remains elusive. To investigate the frequency and clinicopathologic significance of the MYD88 L265P mutation in DLBCLs, we conducted a meta-analysis of 40 publis...

journal_title：Scientific reports

authors： Lee JH,Jeong H,Choi JW,Oh H,Kim YS

更新日期：2017-05-11 00:00:00

abstract：:N(1)-methyladenosine (m(1)A) is a prominent RNA modification involved in many biological processes. Accurate identification of m(1)A site is invaluable for better understanding the biological functions of m(1)A. However, limitations in experimental methods preclude the progress towards the identification of m(1)A site...

journal_title：Scientific reports

authors： Chen W,Feng P,Tang H,Ding H,Lin H

更新日期：2016-08-11 00:00:00

abstract：:The habit of blood feeding evolved independently in many insect orders of families. Sand flies and mosquitoes belong to separate lineages of blood-feeding Diptera and are thus considered to have evolved the trait independently. Because of this, sand fly salivary proteins differ structurally from those of mosquitoes, a...

journal_title：Scientific reports

authors： Jablonka W,Kim IH,Alvarenga PH,Valenzuela JG,Ribeiro JMC,Andersen JF

更新日期：2019-03-29 00:00:00

abstract：:Active video games (exergames) may provide short-term increase in energy expenditure. We explored the effects of gender and prior experience on aerobic and anaerobic energy systems contributions, and the activity profiles of 40 participants playing with a swimming exergame. We recorded oxygen consumption and assessed ...

journal_title：Scientific reports

authors： Soltani P,Figueiredo P,Ribeiro J,Fernandes RJ,Vilas-Boas JP

更新日期：2017-07-12 00:00:00

abstract：:The effect of annealing both in the oxygen atmosphere and at room temperatures on physical properties such as the pseudogap (Δ*(T)) and excess conductivity (σ'(T)) of untwined YBa2Cu3O7-δ (YBCO) single crystal with a small deviation from oxygen stoichiometry is studied. It was revealed that as the charge carrier densi...

journal_title：Scientific reports

authors： Solovjov AL,Petrenko EV,Omelchenko LV,Vovk RV,Goulatis IL,Chroneos A

更新日期：2019-06-25 00:00:00

abstract：:In this study, 111 Cryptosporidium parvum IId isolates from several species of animals in China, Sweden, and Egypt were subtyped by multilocus sequence typing (MLST). One to eleven subtypes were detected at each of the 12 microsatellite, minisatellite, and single nucleotide polymorphism (SNP) loci, forming 25 MLST sub...

journal_title：Scientific reports

authors： Wang R,Zhang L,Axén C,Bjorkman C,Jian F,Amer S,Liu A,Feng Y,Li G,Lv C,Zhao Z,Qi M,Dong H,Wang H,Sun Y,Ning C,Xiao L

更新日期：2014-02-27 00:00:00

abstract：:Astrocyte reactivation has been discovered to be an important contributor to several neurological diseases. In vitro models involving human astrocytes have the potential to reveal disease-specific mechanisms of these cells and to advance research on neuropathological conditions. Here, we induced a reactive phenotype i...

journal_title：Scientific reports

authors： Hyvärinen T,Hagman S,Ristola M,Sukki L,Veijula K,Kreutzer J,Kallio P,Narkilahti S

更新日期：2019-11-15 00:00:00

abstract：:The Pax3/7 transcription factor family is integral to developmental gene networks contributing to important innovations in vertebrate evolution, including the neural crest. The basal chordate lineage of amphioxus is ideally placed to understand the dynamics of the gene regulatory network evolution that produced these ...

journal_title：Scientific reports

authors： Barton-Owen TB,Ferrier DEK,Somorjai IML

更新日期：2018-06-20 00:00:00

abstract：:Quaternized polyacrylic polymer has many applications in water treatment because of its ion exchange effects, but its further industrial applications are largely restricted because of its poor mechanical strength. In this work, a magnetic anion exchange resin with a polyacrylic matrix (MAP) was prepared by incorporati...

journal_title：Scientific reports

authors： Zhang G,Li S,Shuang C,Mu Y,Li A,Tan L

更新日期：2020-03-23 00:00:00

abstract：:Freezing colloidal suspensions widely exists in nature and industry. Interface instability has attracted much attention for the understandings of the pattern formation in freezing colloidal suspensions. However, the interface instability modes, the origin of the ice banding or ice lamellae, are still unclear. In-situ ...

journal_title：Scientific reports

authors： Wang L,You J,Wang Z,Wang J,Lin X

更新日期：2016-03-21 00:00:00

abstract：:Glomerular mesangial cell (GMC) proliferation and matrix expansion are pathological hallmarks of a wide range of kidney diseases, including diabetic nephropathy. Although the circulating level of peptide hormone urotensin II (UII) and kidney tissue expression of UII and UII receptors (UTR) are increased in diabetic ne...

journal_title：Scientific reports

authors： Soni H,Adebiyi A

更新日期：2017-12-22 00:00:00

abstract：:Obesity-induced adipose-tissue dysfunction is a critical contributor to the pathogenesis of nonalcoholic fatty liver disease (NAFLD). B cell-activating factor (BAFF) is an adipokine related to impaired insulin sensitivity, and the serum BAFF concentration is associated with NAFLD severity. In this study, we aimed to d...

journal_title：Scientific reports

authors： Nakamura Y,Abe M,Kawasaki K,Miyake T,Watanabe T,Yoshida O,Hirooka M,Matsuura B,Hiasa Y

更新日期：2019-01-30 00:00:00

abstract：:We report the thermal annealing-induced formation of ring-like structure of Zn(II)-doped magnetite from iron alkoxide leaf-like nanoplate precusor. The phase, structure and morphology of magnetite nanorings were comprehensively characterized by powder X-ray diffraction, X-ray photoelectron spectroscopy, atomic force m...

journal_title：Scientific reports

authors： Yang S,Jiang JT,Xu CY,Wang Y,Xu YY,Cao L,Zhen L

更新日期：2017-04-03 00:00:00

abstract：:Previous studies of protein fold space suggest that fold coverage is plateauing. However, sequence sampling has been -and remains to a large extent- heavily biased, focusing on culturable phyla. Sustained technological developments have fuelled the advent of metagenomics and single-cell sequencing, which might correct...

journal_title：Scientific reports

authors： Barry Roche D,Brüls T

更新日期：2015-10-05 00:00:00

abstract：:Better risk prediction and new molecular targets are key priorities in type 2 diabetes (T2D) research. Little is known about the role of the urine metabolome in predicting the risk of T2D. We aimed to use non-targeted urine metabolomics to discover biomarkers and improve risk prediction for T2D. Urine samples from two...

journal_title：Scientific reports

authors： Salihovic S,Broeckling CD,Ganna A,Prenni JE,Sundström J,Berne C,Lind L,Ingelsson E,Fall T,Ärnlöv J,Nowak C

更新日期：2020-10-05 00:00:00

abstract：:Early treatment of single sided deafness in children has been recommended to protect from neurodevelopmental preference for the better hearing ear and from social and educational deficits. A fairly homogeneous group of five young children (≤3.6 years of age) with normal right sided hearing who received a cochlear impl...

journal_title：Scientific reports

authors： Polonenko MJ,Gordon KA,Cushing SL,Papsin BC

更新日期：2017-12-04 00:00:00

abstract：:The Field Effect sensors are broadly used for detecting various target analytes in chemical and biological solutions. We report the conditions under which the pH sensitivity of an Ion Sensitive Field Effect transistor (ISFET) sensor can be significantly enhanced. Our theory and simulations show that by using pH buffer...

journal_title：Scientific reports

authors： Parizi KB,Xu X,Pal A,Hu X,Wong HS

更新日期：2017-02-02 00:00:00

abstract：:The nervous system controls most rhythmic behaviors, with a remarkable exception. In Caenorhabditis elegans periodic defecation rhythm does not appear to involve the nervous system. Such oscillations are studied in detail with genetic and molecular biology tools. The small size of C. elegans cells impairs the use of s...

journal_title：Scientific reports

authors： Kuznetsov VP,Slivko-Koltchik GA,Voronov DA,Panchin YV

更新日期：2017-12-19 00:00:00

abstract：:For a broad class of input-output maps, arguments based on the coding theorem from algorithmic information theory (AIT) predict that simple (low Kolmogorov complexity) outputs are exponentially more likely to occur upon uniform random sampling of inputs than complex outputs are. Here, we derive probability bounds that...

journal_title：Scientific reports

authors： Dingle K,Pérez GV,Louis AA

更新日期：2020-03-10 00:00:00