Abstract:
:Predicting the occurrence of ventricular tachyarrhythmia (VTA) in advance is a matter of utmost importance for saving the lives of cardiac arrhythmia patients. Machine learning algorithms have been used to predict the occurrence of imminent VTA. In this study, we used a one-dimensional convolutional neural network (1-D CNN) to extract features from heart rate variability (HRV), thereby to predict the onset of VTA. We also compared the prediction performance of our CNN with other machine leaning (ML) algorithms such as an artificial neural network (ANN), a support vector machine (SVM), and a k-nearest neighbor (KNN), which used 11 HRV features extracted using traditional methods. The proposed CNN achieved relatively higher prediction accuracy of 84.6%, while the ANN, SVM, and KNN algorithms obtained prediction accuracies of 73.5%, 67.9%, and 65.9% using 11 HRV features, respectively. Our result showed that the proposed 1-D CNN could improve VTA prediction accuracy by integrating the data cleaning, preprocessing, feature extraction, and prediction.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Taye GT,Hwang HJ,Lim KMdoi
10.1038/s41598-020-63566-8subject
Has Abstractpub_date
2020-04-21 00:00:00pages
6769issue
1issn
2045-2322pii
10.1038/s41598-020-63566-8journal_volume
10pub_type
杂志文章abstract::N6-methyladenosine (m6A) is the most abundant internal modification of eukaryotic mRNA. This modification has previously been shown to alter the export kinetics for mRNAs though the molecular details surrounding this phenomenon remain poorly understood. Recruitment of the TREX mRNA export complex to mRNA is driven by ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-32310-8
更新日期:2018-09-14 00:00:00
abstract::Desertification due to climate change and increasing drought periods is a worldwide problem for both ecology and economy. Our ability to understand how vegetation manages to survive and propagate through arid and semiarid ecosystems may be useful in the development of future strategies to prevent desertification, pres...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep33703
更新日期:2016-09-21 00:00:00
abstract::The advent of Fluorescence Microscopy over the last few years have dramatically improved the problem of visualization and tracking of specific cellular objects for biological inference. But like any other imaging system, fluorescence microscopy has its own limitations. The resultant images suffer from the effect of no...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-43973-2
更新日期:2019-05-22 00:00:00
abstract::A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper. ...
journal_title:Scientific reports
pub_type: 已发布勘误
doi:10.1038/s41598-018-23329-y
更新日期:2018-03-19 00:00:00
abstract::Combining endurance training with resistance training (RT) may attenuate skeletal muscle hypertrophic adaptation versus RT alone; however, the underlying mechanisms are unclear. We investigated changes in markers of ribosome biogenesis, a process linked with skeletal muscle hypertrophy, following concurrent training v...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-18887-6
更新日期:2018-01-12 00:00:00
abstract::Photosynthesis is sensitive to environmental stress and must be efficiently modulated in response to abiotic stress. However, the underlying mechanisms are not well understood. Here we report that ARABIDOPSIS THALIANA HOMEOBOX 17 (ATHB17), an Arabidopsis HD-Zip transcription factor, regulated the expression of a numbe...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep45492
更新日期:2017-03-30 00:00:00
abstract::Breast cancer in young women is typically with higher proportion of adverse pathological features. Breast cancer with BRCA1 mutation is often early-onset, and is usually associated with triple negative phenotpe. In this study, we aim to analyze the clinicopathological characteristics and prognosis in young breast canc...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep05360
更新日期:2014-06-19 00:00:00
abstract::Tunneling membrane nanotubes (TnTs) are membrane protrusions connecting nearby or distant cells in vitro and in vivo. Functions of TnTs in cellular processes are various and rely on TnT structure, which also depends on cytoskeletal composition. In the present study, we focused on the organization of microtubules (MTs)...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-35370-y
更新日期:2018-11-20 00:00:00
abstract::The charge transport properties of hybrid halide perovskites are investigated with a combination of density functional theory including van der Waals interaction and the Boltzmann theory for diffusive transport in the relaxation time approximation. We find the mobility of electrons to be in the range 5-10 cm(2)V(-1)s(...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep12746
更新日期:2015-08-03 00:00:00
abstract::Despite recent advances in melanoma treatment, metastasis and resistance to therapy remain serious clinical challenges. NME1 is a metastasis suppressor, a class of proteins which inhibits metastatic spread of cancer cells without impact on growth of the primary tumor. We have identified a rare subpopulation of cells w...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-58996-3
更新日期:2020-02-06 00:00:00
abstract::Cystic fibrosis (CF) patients experience heightened levels of anxiety and depression. Stress from dealing with chronic disease and rigorous treatment regimens certainly are primary contributors to these outcomes. We previously have demonstrated that microtubule alterations in CF are linked to a number of CF phenotypes...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-73298-4
更新日期:2020-10-01 00:00:00
abstract::Glomerular mesangial cell (GMC) proliferation and matrix expansion are pathological hallmarks of a wide range of kidney diseases, including diabetic nephropathy. Although the circulating level of peptide hormone urotensin II (UII) and kidney tissue expression of UII and UII receptors (UTR) are increased in diabetic ne...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-18143-x
更新日期:2017-12-22 00:00:00
abstract::Automatically detecting and grading cancerous regions on radical prostatectomy (RP) sections facilitates graphical and quantitative pathology reporting, potentially benefitting post-surgery prognosis, recurrence prediction, and treatment planning after RP. Promising results for detecting and grading prostate cancer on...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-66849-2
更新日期:2020-06-18 00:00:00
abstract::Invasive motor Cortex Stimulation (iMCS) was introduced in the 1990's for the treatment of chronic neuropathic orofacial pain (CNOP), although its effectiveness remains doubtful. However, CNOP is known to be a heterogeneous group of orofacial pain disorders, which can lead to different responses to iMCS. Therefore, th...
journal_title:Scientific reports
pub_type: 杂志文章,meta分析
doi:10.1038/s41598-020-64177-z
更新日期:2020-04-28 00:00:00
abstract::The overall objective of this study was to test the hypothesis that +Gz (hypergravity/positive acceleration) and microgravity can both aggravate intervertebral disc degeneration (IVDD). Due to +Gz and microgravity, many pilots develop IVDD. However, the lack of animal models of IVDD under conditions of simulated +Gz a...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-53246-7
更新日期:2019-11-12 00:00:00
abstract::Lipofectamine reagents are widely accepted as "gold-standard" for the safe delivery of exogenous DNA or RNA into cells. Despite this, a satisfactory mechanism-based explanation of their superior efficacy has remained mostly elusive thus far. Here we apply a straightforward combination of live cell imaging, single-part...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep25879
更新日期:2016-05-11 00:00:00
abstract::The objective of this study was to evaluate the stimulatory effects of Bacillus amyloliquefaciens SQR9 on dendritic cells (DCs) and to verify its ability to enhance the immune response by modulating DC maturation. The results demonstrated that B. amyloliquefaciens SQR9 can adhere to the nasal epithelium and be taken u...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep21363
更新日期:2016-02-19 00:00:00
abstract::Hydrogen sulfide (H2S) is an important biological messenger, but few biologically-compatible methods are available for its detection in aqueous solution. Herein, we report a highly water-soluble naphthalimide-based fluorescent probe (L1), which is a highly versatile building unit that absorbs and emits at long wavelen...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep26203
更新日期:2016-05-18 00:00:00
abstract::Long-read sequencing technologies such as Pacific Biosciences and Oxford Nanopore MinION are capable of producing long sequencing reads with average fragment lengths of over 10,000 base-pairs and maximum lengths reaching 100,000 base- pairs. Compared with short reads, the assemblies obtained from long-read sequencing ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-03996-z
更新日期:2017-06-21 00:00:00
abstract::The PIM1 serine/threonine protein kinase mediates growth factor and survival signalling, and cooperates potently with c-MYC during tumorigenesis. PIM1 is overexpressed in many human cancers and is a promising target for drug development. PIM1 levels are regulated mainly through cytokine-induced transcription and prote...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-03775-w
更新日期:2017-06-15 00:00:00
abstract::While previous studies separately demonstrate EEG spectral modulations during speech preparation and ERP responses to the listened speech, it is unclear whether these responses are related on a trial-by-trial basis between a speaker and listener. In order to determine whether these responses are related in real-time, ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-31038-9
更新日期:2018-08-27 00:00:00
abstract::In spite of intensive investigations, the role of spontaneous breathing (SB) activity in ARDS has not been well defined yet and little has been known about the different contribution of inspiratory or expiratory muscles activities during mechanical ventilation in patients with ARDS. In present study, oleic acid-induce...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep42785
更新日期:2017-02-23 00:00:00
abstract::Coffee is a major tropical commodity crop that can provide supplementary habitat for native wildlife. In Asia, coffee production is an increasingly important driver of landscape transformation and shifts between different coffee species is a major dimension of agroforestry trends. Yet few studies have compared the eco...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-21401-1
更新日期:2018-02-16 00:00:00
abstract::Stem cell therapy that can restore function to damaged tissue, avoid host rejection and reduce inflammation throughout body without use of immunosuppressive drugs. The established methods were used to identify and to isolate specific stem cell markers by FACS or by immunomagnetic cell separation. The procedures for di...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-09543-0
更新日期:2017-08-29 00:00:00
abstract::Alzheimer's disease (AD) is one of the most prevalent neurodegenerative diseases, yet current therapeutic treatments are inadequate due to a complex disease pathogenesis. The plant polyphenol apigenin has been shown to have anti-inflammatory and neuroprotective properties in a number of cell and animal models; however...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep31450
更新日期:2016-08-12 00:00:00
abstract::Amblyopia is a common visual disorder that is treatable in childhood. However, therapies have limited efficacy in adult patients with amblyopia. Fluoxetine can reinstate early-life critical period-like neuronal plasticity and has been used to recover functional vision in adult rats with amblyopia. We conducted a Phase...
journal_title:Scientific reports
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1038/s41598-018-31169-z
更新日期:2018-08-27 00:00:00
abstract::The chemiresistive thin film gas sensors with fast response, high sensitivity, low power consumption and mass-produced potency, have been expected for practical application. It requires both sensitive materials, especially exquisite nanomaterials, and efficient substrate chip for heating and electrical addressing. How...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep01669
更新日期:2013-01-01 00:00:00
abstract::Marine macroalgal forests are highly productive and iconic ecosystems, which are seriously threatened by number of factors such as habitat destruction, overgrazing, ocean warming, and pollution. The effect of chronic, but low levels of pollutants on the long-term survival of the canopy-forming algae is not well unders...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-73990-5
更新日期:2020-10-20 00:00:00
abstract::Knockin (KI) mouse carrying a point mutation has been an invaluable tool for disease modeling and analysis. Genome editing technologies using the CRISPR/Cas system has emerged as an alternative way to create KI mice. However, if the mice carry nucleotide insertions and/or deletions (InDels) in other genes, which could...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep34703
更新日期:2016-10-04 00:00:00
abstract::Fusarium Head Blight (FHB) caused by Fusarium graminearum pathogens constitutes a major threat to agricultural production because it frequently reduces the yield and quality of the crop. The disease severity is predicted to increase in various regions owing to climate change. Integrated management where biocontrol pla...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-37718-w
更新日期:2019-01-24 00:00:00