ISFET pH Sensitivity: Counter-Ions Play a Key Role.

Abstract:

:The Field Effect sensors are broadly used for detecting various target analytes in chemical and biological solutions. We report the conditions under which the pH sensitivity of an Ion Sensitive Field Effect transistor (ISFET) sensor can be significantly enhanced. Our theory and simulations show that by using pH buffer solutions containing counter-ions that are beyond a specific size, the sensor shows significantly higher sensitivity which can exceed the Nernst limit. We validate the theory by measuring the pH response of an extended gate ISFET pH sensor. The consistency and reproducibility of the measurement results have been recorded in hysteresis free and stable operations. Different conditions have been tested to confirm the accuracy and validity of our experiment results such as using different solutions, various oxide dielectrics as the sensing layer and off-the-shelf versus IC fabricated transistors as the basis of the ISFET sensor.

journal_name

Sci Rep

journal_title

Scientific reports

authors

Parizi KB,Xu X,Pal A,Hu X,Wong HS

doi

10.1038/srep41305

subject

Has Abstract

pub_date

2017-02-02 00:00:00

pages

41305

issn

2045-2322

pii

srep41305

journal_volume

7

pub_type

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