Antibody-dependent-cellular-cytotoxicity-inducing antibodies significantly affect the post-exposure treatment of Ebola virus infection.

abstract：:To tailor the properties of colloidal materials, precise control over the self-assembly of their constituents is a prerequisite. Here, we govern the assembly of silica particles by functionalization with supramolecular moieties which interact with each other via directional and reversible hydrogen bonding. Through a g...

journal_title：Scientific reports

authors： Vilanova N,Feijter I,Teunissen AJP,Voets IK

更新日期：2018-01-19 00:00:00

abstract：:Regular exercise elicits advantageous metabolic adaptations in skeletal muscle, such as improved insulin sensitivity. However, the underpinning molecular mechanisms and the effect of diet on muscle exercise training benefits are unclear. We therefore characterized the skeletal muscle proteome following exercise traini...

journal_title：Scientific reports

authors： Kleinert M,Parker BL,Jensen TE,Raun SH,Pham P,Han X,James DE,Richter EA,Sylow L

更新日期：2018-07-16 00:00:00

abstract：:We analysed the ligand-based activation mechanism of the prostate-specific G-protein coupled receptor (PSGR), which is an olfactory receptor that mediates cellular growth in prostate cancer cells. Furthermore, it is an olfactory receptor with a known chemically near identic antagonist/agonist pair, α- and β-ionone. Us...

journal_title：Scientific reports

authors： Wolf S,Jovancevic N,Gelis L,Pietsch S,Hatt H,Gerwert K

更新日期：2017-11-22 00:00:00

abstract：:This study presents atomic scale characterization of grain boundary defect structure in a functional oxide with implications for a wide range of electrochemical and electronic behavior. Indeed, grain boundary engineering can alter transport and kinetic properties by several orders of magnitude. Here we report experime...

journal_title：Scientific reports

authors： An J,Park JS,Koh AL,Lee HB,Jung HJ,Schoonman J,Sinclair R,Gür TM,Prinz FB

更新日期：2013-01-01 00:00:00

abstract：:Cd3As2 has long been known as a high-mobility semiconductor. The recent finding of a topological semimetal state in this compound has demanded growth of epitaxial films with high crystallinity and controlled thickness. Here we report the structural characterisation of Cd3As2 films grown on SrTiO3 substrates by solid-p...

journal_title：Scientific reports

authors： Nakazawa Y,Uchida M,Nishihaya S,Kriener M,Kozuka Y,Taguchi Y,Kawasaki M

更新日期：2018-02-02 00:00:00

abstract：:Metastasis causes approximately 90% of breast cancer-related deaths in women. Previously, we have demonstrated that 2-dodecyl-6-methoxycyclohexa-2,5-diene- 1,4-dione (DMDD) remarkably inhibited the growth of human breast cancer cells with little toxicity. In this study, we investigated the toxicity and efficacy of DMD...

journal_title：Scientific reports

authors： Chen C,Nong Z,Xie Q,He J,Cai W,Tang X,Chen X,Huang R,Gao Y

更新日期：2017-07-27 00:00:00

abstract：:Sapphirinid copepods, which are marine zooplankton, exhibit tunable structural colors originating from a layered structure of guanine crystal plates. In the present study, the coloring portion of adult male of a sapphirinid copepod, Sapphirina nigromaculata, under the dorsal body surface was characterized to clarify t...

journal_title：Scientific reports

authors： Kimura T,Takasaki M,Hatai R,Nagai Y,Uematsu K,Oaki Y,Osada M,Tsuda H,Ishigure T,Toyofuku T,Shimode S,Imai H

更新日期：2020-02-10 00:00:00

abstract：:X-ray free-electron lasers (XFELs) provide extremely bright and highly spatially coherent x-ray radiation with femtosecond pulse duration. Currently, they are widely used in biology and material science. Knowledge of the XFEL statistical properties during an experiment may be vitally important for the accurate interpr...

journal_title：Scientific reports

authors： Gorobtsov OY,Mukharamova N,Lazarev S,Chollet M,Zhu D,Feng Y,Kurta RP,Meijer JM,Williams G,Sikorski M,Song S,Dzhigaev D,Serkez S,Singer A,Petukhov AV,Vartanyants IA

更新日期：2018-02-02 00:00:00

abstract：:Lung fibrosis is an unabated wound healing response characterized by the loss and aberrant function of lung epithelial cells. Herein, we report that extracellular Clusterin promoted epithelial cell apoptosis whereas intracellular Clusterin maintained epithelium viability during lung repair. Unlike normal and COPD lung...

journal_title：Scientific reports

authors： Habiel DM,Camelo A,Espindola M,Burwell T,Hanna R,Miranda E,Carruthers A,Bell M,Coelho AL,Liu H,Pilataxi F,Clarke L,Grant E,Lewis A,Moore B,Knight DA,Hogaboam CM,Murray LA

更新日期：2017-11-13 00:00:00

abstract：:It is estimated from twin studies that heritable factors account for at-least half of asthma-risk, of which genetic variants identified through population studies explain only a small fraction. Multi-generation large families with high asthma prevalence can serve as a model to identify highly penetrant genetic variant...

journal_title：Scientific reports

authors： Chakraborty S,Dakle P,Sinha A,Vishweswaraiah S,Nagori A,Salimath S,Prakash YS,Lodha R,Kabra SK,Ghosh B,Faruq M,Mahesh PA,Agrawal A

更新日期：2019-12-13 00:00:00

abstract：:We investigate the timescales of the horizontal mass flux decay of wind remobilised volcanic particles in Argentina, associated with the tephra-fallout deposit produced by the 2011-2012 Cordón Caulle (Chile) eruption. Particle removal processes are controlled by complex interactions of meteorological conditions, surfa...

journal_title：Scientific reports

authors： Dominguez L,Rossi E,Mingari L,Bonadonna C,Forte P,Panebianco JE,Bran D

更新日期：2020-09-02 00:00:00

abstract：:In this work, a novel technique to create positive-negative tunable liquid crystal lenses is proposed and experimentally demonstrated. This structure is based on two main elements, a transmission line acting as a voltage divider and concentric electrodes that distribute the voltage homogeneously across the active area...

journal_title：Scientific reports

authors： Algorri JF,Morawiak P,Bennis N,Zografopoulos DC,Urruchi V,Rodríguez-Cobo L,Jaroszewicz LR,Sánchez-Pena JM,López-Higuera JM

更新日期：2020-06-23 00:00:00

abstract：:What's on the label is not what's in the bottle, from food products to herbal medicinal products (HMPs), economically-motivated biomaterials adulteration is a long-term problem affecting the food and drug industry. Accurate identification of the biomaterial ingredients in processed commodities is highly desirable. In ...

journal_title：Scientific reports

authors： Chen R,Wang J,Yuan Y,Deng Y,Lai X,Du F,Dong J,Huang X,Cui X,Tang Z

更新日期：2017-07-06 00:00:00

abstract：:Nucleotide excision repair (NER) excises bulky DNA lesions induced by mutagens and carcinogens. The repair process includes recognition of DNA damage, excision of a short patch of nucleotides containing the damaged base, re-synthesis of a new DNA strand and ligation of the nicks to restore the sequence integrity. Muta...

journal_title：Scientific reports

authors： Shen JC,Fox EJ,Ahn EH,Loeb LA

更新日期：2014-05-08 00:00:00

abstract：:Recent studies suggest a functional involvement of Epithelial-Mesenchymal Transition (EMT) in tumor chemoresistance. Specifically, EMT is associated with chemoresistance and poor prognosis in triple-negative breast cancer. However, no effective therapy targeting EMT has been developed. Here, we report that periostin, ...

journal_title：Scientific reports

authors： Nakazawa Y,Taniyama Y,Sanada F,Morishita R,Nakamori S,Morimoto K,Yeung KT,Yang J

更新日期：2018-03-05 00:00:00

abstract：:Enterococci are nosocomial pathogens that can form biofilms, which contribute to their virulence and antibiotic resistance. Although many genes involved in biofilm formation have been defined, their distribution among enterococci has not been comprehensively studied on a genome scale, and their diagnostic ability to p...

journal_title：Scientific reports

authors： Hashem YA,Amin HM,Essam TM,Yassin AS,Aziz RK

更新日期：2017-07-18 00:00:00

abstract：:A complete understanding of signaling processes at the plasma membrane depends on a quantitative characterization of the interactions of the involved proteins. Fluorescence recovery after photobleaching (FRAP) is a widely used and convenient technique to obtain kinetic parameters on protein interactions in living cell...

journal_title：Scientific reports

authors： Motsch V,Brameshuber M,Baumgart F,Schütz GJ,Sevcsik E

更新日期：2019-03-01 00:00:00

abstract：:In a haptic search task, one has to detect the presence of a target among distractors using the sense of touch. A salient target can be detected faster than a non-salient target. However, little is known about the exploration strategies that are used, especially in 3D search tasks where items are held in the hand. In ...

journal_title：Scientific reports

authors： van Polanen V,Bergmann Tiest WM,Kappers AM

更新日期：2014-09-03 00:00:00

abstract：:Dendritic Cells (DCs) recognize infectious non-self molecules and engage the adaptive immune system thereby initiating long lasting, antigen-specific responses. As such, the ability to activate DCs is considered a key tool to enhance the efficacy and quality of vaccination. Here we report a novel immunomodulatory sulf...

journal_title：Scientific reports

authors： Manzo E,Cutignano A,Pagano D,Gallo C,Barra G,Nuzzo G,Sansone C,Ianora A,Urbanek K,Fenoglio D,Ferrera F,Bernardi C,Parodi A,Pasquale G,Leonardi A,Filaci G,De Palma R,Fontana A

更新日期：2017-07-24 00:00:00

abstract：:The protective effect of estrogens against chronic glomerular diseases is admitted but remains debated during acute kidney injury (AKI). Using a model of resuscitated hemorrhagic shock in C57/Bl6 female mice, this study evaluated at 1 and 21 days the renal effect of (1) endogenous estrogen, using ovariectomized mice w...

journal_title：Scientific reports

authors： Buléon M,Cuny M,Grellier J,Charles PY,Belliere J,Casemayou A,Arnal JF,Schanstra JP,Tack I

更新日期：2020-10-14 00:00:00

abstract：:Treatment of decompensated heart failure often includes administration of levosimendan. Myeloperoxidase (MPO) is released during polymorphonuclear neutrophil (PMN) degranulation, and mediates dysregulation of vascular tone in heart failure. We evaluated the effects of levosimendan-treatment on MPO in patients with acu...

journal_title：Scientific reports

authors： Adam M,Meyer S,Knors H,Klinke A,Radunski UK,Rudolph TK,Rudolph V,Spin JM,Tsao PS,Costard-Jäckle A,Baldus S

更新日期：2015-04-13 00:00:00

abstract：:We examined whether it is possible to identify individual subjects on the basis of brain anatomical features. For this, we analyzed a dataset comprising 191 subjects who were scanned three times over a period of two years. Based on FreeSurfer routines, we generated three datasets covering 148 anatomical regions (corti...

journal_title：Scientific reports

authors： Valizadeh SA,Liem F,Mérillat S,Hänggi J,Jäncke L

更新日期：2018-04-04 00:00:00

abstract：:Transcriptome analysis by RNA-seq technology allows novel insights into gene expression and regulatory networks in health and disease. To better understand the molecular basis of renal fibrosis, we performed RNA-seq analysis in the Unilateral Ureteric Obstruction (UUO) mouse model. We analysed sham operated, 2- and 8-...

journal_title：Scientific reports

authors： Arvaniti E,Moulos P,Vakrakou A,Chatziantoniou C,Chadjichristos C,Kavvadas P,Charonis A,Politis PK

更新日期：2016-05-18 00:00:00

abstract：:The DEAD-box RNA helicase DDX3 plays divergent roles in tumorigenesis, however, its function in mitosis is unclear. Immunofluorescence indicated that DDX3 localized to centrosome throughout the cell cycle and colocalized with centrosome-associated p53 during mitosis in HCT116 and U2OS cells. DDX3 depletion promoted ch...

journal_title：Scientific reports

authors： Chen WJ,Wang WT,Tsai TY,Li HK,Lee YW

更新日期：2017-08-25 00:00:00

abstract：:The IκB kinase (IKK) complex acts as the gatekeeper of canonical NF-κB signaling, thereby regulating immunity, inflammation and cancer. It consists of the catalytic subunits IKKα and IKKβ and the regulatory subunit NEMO/IKKγ. Here, we show that the ubiquitin binding domain (UBAN) in NEMO is essential for IKK/NF-κB act...

journal_title：Scientific reports

authors： Vincendeau M,Hadian K,Messias AC,Brenke JK,Halander J,Griesbach R,Greczmiel U,Bertossi A,Stehle R,Nagel D,Demski K,Velvarska H,Niessing D,Geerlof A,Sattler M,Krappmann D

更新日期：2016-01-07 00:00:00

abstract：:The current flowing through a Mott spin junction depends on the relative spin orientation of the two ferromagnetic layers comprising the "source" and "drain" sides of the junction. The resulting current asymmetry is detected as giant or tunnelling magnetoresistance depending on whether the two ferromagnets are separat...

journal_title：Scientific reports

authors： De Pietro L,Bertolini G,Peter Q,Cabrera H,Vindigni A,Gürlü O,Pescia D,Ramsperger U

更新日期：2017-10-16 00:00:00

abstract：:Among the range of complex interactions, especially at the interfaces of epitaxial oxide systems, contributing to the occurrence of intriguing effects, a predominant role is played by the local structural parameters. In this study, oxide molecular beam epitaxy grown lanthanum cuprate-based bilayers (consisting of a me...

journal_title：Scientific reports

authors： Suyolcu YE,Wang Y,Baiutti F,Al-Temimy A,Gregori G,Cristiani G,Sigle W,Maier J,van Aken PA,Logvenov G

更新日期：2017-03-28 00:00:00

abstract：:Drought stress and pathogen infection simultaneously occur in the field. In this study, the interaction of these two stresses with chickpea, their individual and combined effect and the net impact on plant growth and yield traits were systematically assessed under field and confined pot experiments. The field experime...

journal_title：Scientific reports

authors： Sinha R,Irulappan V,Mohan-Raju B,Suganthi A,Senthil-Kumar M

更新日期：2019-04-03 00:00:00

abstract：:With countless biological details emerging from cancer experiments, there is a growing need for minimal mathematical models which simultaneously advance our understanding of single tumors and metastasis, provide patient-personalized predictions, whilst avoiding excessive hard-to-measure input parameters which complica...

journal_title：Scientific reports

authors： Choe SC,Zhao G,Zhao Z,Rosenblatt JD,Cho HM,Shin SU,Johnson NF

更新日期：2011-01-01 00:00:00

abstract：:There is a demand for ultra low-loss metal films with high-quality single crystals and perfect surface for nanophotonics and quantum information processing. Many researches are devoted to alternative materials, but silver is by far theoretically the most preferred low-loss material at optical and near-IR frequencies. ...

journal_title：Scientific reports

authors： Rodionov IA,Baburin AS,Gabidullin AR,Maklakov SS,Peters S,Ryzhikov IA,Andriyash AV

更新日期：2019-08-22 00:00:00