Abstract：
:To tailor the properties of colloidal materials, precise control over the self-assembly of their constituents is a prerequisite. Here, we govern the assembly of silica particles by functionalization with supramolecular moieties which interact with each other via directional and reversible hydrogen bonding. Through a generally applicable synthesis protocol, two different types of self-complementary hydrogen bonding moieties, BTA- and UPy-derivatives, are anchored to silica particles. Their self-assembly is initiated by the UV-induced removal of a photolabile protecting group, allowing the formation of hydrogen bonds between tethered molecules. The light-induced assembly of BTA- and UPy-decorated colloids in single-component dispersions and colloidal self-sorting in mixed dispersions is studied. Furthermore, we demonstrate that UPy-colloids can dissasemble upon addition of traces of a competitive binder (NaPy). This work provides further insight into the utility of supramolecular handles to orchestrate the assembly of micron-sized colloids via non-oligonucleotide hydrogen-bonding units.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Vilanova N,Feijter I,Teunissen AJP,Voets IKdoi
10.1038/s41598-018-19282-5subject
Has Abstractpub_date
2018-01-19 00:00:00pages
1271issue
1issn
2045-2322pii
10.1038/s41598-018-19282-5journal_volume
8pub_type
杂志文章abstract：:We characterized the microstructural response of the myocardium to cardiovascular disease using diffusion tensor imaging (DTI) and performed histological validation by intact, un-sectioned, three-dimensional (3D) histology using a tissue-clearing technique. The approach was validated in normal (n = 7) and ischemic (n ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-24622-6
更新日期：2018-04-27 00:00:00
abstract：:Pseudoxanthoma Elasticum (PXE) is a rare disorder characterized by fragmentation and progressive calcification of elastic fibres in connective tissues. Although arterial hypertension (AHT) has been reported in PXE patients, its impact on pathological manifestations has as yet been unexplored. We investigated the conse...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-52808-z
更新日期：2019-11-08 00:00:00
abstract：:Epidermal growth factor receptor (EGFR) is a member of the receptor tyrosine kinases ErbB family and it is found to be overexpressed in gastric cancer. However, the mechanism of the regulation of the EGFR expression is still unknown. We used the Sequenom EpiTYPER assay to detect the methylation status of the EGFR prom...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep10154
更新日期：2015-05-11 00:00:00
abstract：:A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper. ...
journal_title：Scientific reports
pub_type： 已发布勘误
doi：10.1038/s41598-018-36667-8
更新日期：2018-12-12 00:00:00
abstract：:Anticarsia gemmatalis (velvetbean caterpillar) and Chrysodeixis includens (soybean looper) are two important defoliation pests of soybeans. In the present study, we have investigated the susceptibility and brush border membrane-binding properties of both species to Bacillus thuringiensis Cry1Ea toxin. Bioassays perfor...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-54850-3
更新日期：2019-12-03 00:00:00
abstract：:The prevalence of chronic kidney disease (CKD), characterized by progressive renal dysfunction with tubulointerstitial fibrosis, is increasing because of societal aging. Uremic toxins, accumulated during renal dysfunction, cause kidney damage, leading to renal deterioration. A recent metabolomic analysis revealed that...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-11049-8
更新日期：2017-09-11 00:00:00
abstract：:There are only few studies that explore the ecological consequences of forest management on several organism groups. We studied the short-term effects of four forestry treatments including preparation cutting, clear-cutting, retention tree group and gap-cutting in a temperate managed forest on the assemblage structure...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-35159-z
更新日期：2018-11-19 00:00:00
abstract：:Understanding the excited-state dynamics in perovskite photovoltaics is necessary for progress in these materials, but changes in dynamics depending on the fabrication processes used for perovskite photoactive layers remain poorly characterised. Here we report a comparative study on femtosecond transient absorption (T...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-16654-1
更新日期：2017-11-28 00:00:00
abstract：:The objective of this study was to examine the relationship between sleep duration and ischemic and hemorrhagic stroke in a community-based cohort. The current analysis included 95,023 Chinese participants who were free of stroke at the baseline survey (2006-2007). Cox proportional hazards models were used to calculat...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep33664
更新日期：2016-09-16 00:00:00
abstract：:Using dedicated contrast agents high-quality X-ray imaging of soft tissue structures with isotropic micrometre resolution has become feasible. This technique is frequently titled as virtual histology as it allows production of slices of tissue without destroying the sample. The use of contrast agents is, however, ofte...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep30385
更新日期：2016-07-27 00:00:00
abstract：:Dengue fever is one of the most important mosquito-borne viral infections in large parts of tropical and subtropical countries and is a significant public health concern and socioeconomic burden. There is an urgent need to develop antivirals that can effectively reduce dengue virus (DENV) replication and decrease vira...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-45095-1
更新日期：2019-06-18 00:00:00
abstract：:The extensive redundancy in the use of invasion ligands by Plasmodium falciparum, and its unique ability to switch between invasion pathways have hampered vaccine development. P. falciparum strains Dd2 and W2mef have been shown to change from sialic acid (SA)-dependent to SA-independent phenotypes when selected on neu...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-24218-0
更新日期：2018-04-10 00:00:00
abstract：:Systemic lupus erythematosus (SLE) is a multisystemic autoimmune disease that is associated with the destruction of immune tolerance and activation of B cells. Interleukin (IL)-35 and IL-35-producing (IL-35+) regulatory B cells (Bregs) have been demonstrated to possess immunosuppressive functions, but their roles in t...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-49748-z
更新日期：2019-09-13 00:00:00
abstract：:The formation of snow-dirt sludge (SDS) via the mixing of snow and surface-deposited sediment by vehicles and pedestrians is one of the least studied sedimentation processes in urban areas. The aim of this study was to analyse the material, mineral, particle size, and chemical compositions of the SDS solid phase. The ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-53793-z
更新日期：2019-11-21 00:00:00
abstract：:Gelatin-methacryloyl (GelMA) is one of the most commonly used photopolymerizable biomaterials in bio-applications. However, GelMA synthesis remains suboptimal, as its reaction parameters have not been fully investigated. The goal of this study is to establish an optimal route for effective and controllable GelMA synth...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep31036
更新日期：2016-08-09 00:00:00
abstract：:Capable of mediating efficient transfection and protein production without eliciting innate immune responses, chemically modified mRNA holds great potential to produce paracrine factors at a physiologically beneficial level, in a spatiotemporally controlled manner, and with low toxicity. Although highly promising in c...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-35570-6
更新日期：2018-11-30 00:00:00
abstract：:Our study aimed to investigate the effect of Pap smear screening on stage at diagnosis of cervical cancer in a heterogeneous population of Thai women. Data was merged from the population-based cancer registry and screening registry based on unique identification numbers from 2006 to 2014. Patients being screened had l...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-52607-6
更新日期：2019-11-15 00:00:00
abstract：:Chemokines promote leukocyte recruitment during inflammation. The oxidative burst is an important effector mechanism, this leads to the generation of reactive nitrogen species (RNS), including peroxynitrite (ONOO). The current study was performed to determine the potential for nitration to alter the chemical and biolo...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep44384
更新日期：2017-03-14 00:00:00
abstract：:The sedimentary record, and associated micropalaeontological proxies, is one tool that has been employed to quantify a region's tropical cyclone history. Doing so has largely relied on the identification of allochthonous deposits (sediments and microfossils), sourced from deeper water and entrained by tropical cyclone...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep24846
更新日期：2016-04-29 00:00:00
abstract：:As part of efforts to reduce pressure on the Amazon and other biomes, one approach considered by Brazilian authorities and scientists is more intensive use of the soils of the interior of the northeast of the country, which are generally sandy, with low contents of organic matter and low water holding capacity and are...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-28794-z
更新日期：2018-07-16 00:00:00
abstract：:Aldosterone antagonists slow the progression of chronic kidney disease (CKD), but their use is limited by hyperkalemia, especially when associated with RAS inhibitors. We examined the renoprotective effects of Ly, a novel non-steroidal mineralocorticoid receptor (MR) blocker, through two experimental protocols: In Pro...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-08383-2
更新日期：2017-08-11 00:00:00
abstract：:This study aimed to investigate the dosimetric characteristics of an isocentrically shielded RapidArc (IS-RA) technique for treatment of locally recurrent nasopharyngeal cancer (lrNPC). In IS-RA, the isocenter was placed at the center of the pre-irradiated brainstem (BS)/spinal cord (SC) and the jaws were set to shiel...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep25959
更新日期：2016-05-13 00:00:00
abstract：:CIC-DUX4 sarcoma (CDS) is a group of rare, mesenchymal, small round cell tumours that harbour the unique CIC-DUX4 translocation, which causes aberrant gene expression. CDS exhibits an aggressive course and poor clinical outcome, thus novel therapeutic approaches are needed for CDS treatment. Although patient-derived c...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-04967-0
更新日期：2017-07-05 00:00:00
abstract：:Because histologic types are subjective and difficult to reproduce between pathologists, tissue morphology often takes a back seat to molecular testing for the selection of breast cancer treatments. This work explores whether a deep-learning algorithm can learn objective histologic H&E features that predict the clinic...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-64156-4
更新日期：2020-04-29 00:00:00
abstract：:Crohn's disease (CD) has been associated with an increased consumption of n-6 polyunsaturated fatty acid (PUFA), while greater intake of n-3 PUFA has been associated with a reduced risk. We sought to investigate serum fatty acid composition in CD, and associations of fatty acids with disease activity, cytokines, and a...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-39232-z
更新日期：2019-02-27 00:00:00
abstract：:Porous materials display enhanced scattering mechanisms that greatly influence their transport properties. Metal-assisted chemical etching (MACE) enables fabrication of porous silicon nanowires starting from a doped Si wafer by using a metal template that catalyzes the etching process. Here, we report on the low therm...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-30223-0
更新日期：2018-08-24 00:00:00
abstract：:It has been shown that long-term stimulant consumption alters the biological and microbiological status of the oral cavity. We present a pilot study describing stimulant-specific oral immunomodulation in the oral cavity. Changes in salivary cytokine levels in response to long-term alcohol, tobacco and caffeine were id...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-35094-z
更新日期：2018-11-12 00:00:00
abstract：:In HIV-1/HCV-coinfected patients, chronic HCV infection leads to an increased T-lymphocyte immune activation compared to HIV-monoinfected patients, thereby likely contributing to increase HIV-1 reservoir that is the major barrier for its eradication. Our objective was to evaluate the influence of HCV coinfection in HI...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-41788-9
更新日期：2019-04-03 00:00:00
abstract：:The aim of this study was to identify novel plasma metabolic signatures with possible relevance during multiple myeloma (MM) development and progression. A biochemical quantitative phenotyping platform based on targeted electrospray ionization tandem mass spectrometry technology was used to aid in the identification o...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-75862-4
更新日期：2020-12-14 00:00:00
abstract：:Although technology has triumphed in facilitating routine genome sequencing, new challenges have been created for the data-analyst. Genome-scale surveys of human variation generate volumes of data that far exceed capabilities for laboratory characterization. By incorporating functional annotations as predictors, stati...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep13373
更新日期：2015-08-24 00:00:00
