Taxon-specific responses to different forestry treatments in a temperate forest.

abstract：:PCR inhibitors in clinical specimens negatively affect the sensitivity of diagnostic PCR and RT-PCR or may even cause false-negative results. To overcome PCR inhibition, increase the sensitivity of the assays and simplify the detection protocols, simple methods based on quantitative nested real-time PCR and RT-PCR wer...

journal_title：Scientific reports

authors： Cai D,Behrmann O,Hufert F,Dame G,Urban G

更新日期：2018-02-21 00:00:00

abstract：:Marek's disease virus (MDV) is a preferred vector in the construction of recombinant vaccines. However, bivalent vaccine based on MDV that confers full protection against both very virulent Marek's and infectious bursal disease virus (IBDV) infections in chickens has not been produced. Here we developed a system utili...

journal_title：Scientific reports

authors： Li K,Liu Y,Liu C,Gao L,Zhang Y,Cui H,Gao Y,Qi X,Zhong L,Wang X

更新日期：2016-12-16 00:00:00

abstract：:Hepatocyte-specific HMGB1 deletion has been found to worsen the injury and inflammation in liver ischemia-reperfusion injury (IRI), highlighting a role for intracellular HMGB1 in cellular protection. Down-regulation of nuclear HMGB1 by small interfering RNA (siRNA) might not only decrease its injurious extracellular r...

journal_title：Scientific reports

authors： Zhao G,Fu C,Wang L,Zhu L,Yan Y,Xiang Y,Zheng F,Gong F,Chen S,Chen G

更新日期：2017-04-06 00:00:00

abstract：:Embryonic cryopreservation has a relatively low survival rate because of cytoskeletal damage. However, molecular anti-freezing mechanisms have been largely unexplored. This study investigated the significance of RhoA, involved in embryonic development, and the Rho/RhoA-associated kinase (ROCK) signalling pathway in cr...

journal_title：Scientific reports

authors： Gu M,Ni H,Sheng X,Pauciullo A,Liu Y,Guo Y

更新日期：2017-07-27 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Baiocchini A,Del Nonno F,Taibi C,Visco-Comandini U,D'Offizi G,Piacentini M,Falasca L

更新日期：2020-01-24 00:00:00

abstract：:Bone tissues have trabecular bone with a high bone turnover and cortical bone with a low turnover. The mechanisms by which the turnover rate of these bone tissues is determined remain unclear. Osteocytes secrete sclerostin, a Wnt/β-catenin signaling antagonist, and inhibit bone formation. We found that sclerostin expr...

journal_title：Scientific reports

authors： Koide M,Yamashita T,Murakami K,Uehara S,Nakamura K,Nakamura M,Matsushita M,Ara T,Yasuda H,Penninger JM,Takahashi N,Udagawa N,Kobayashi Y

更新日期：2020-08-13 00:00:00

abstract：:Cuprizone-induced demyelination in mice is a frequently used model in preclinical multiple sclerosis research. A recent quantitative clinically-targeted MRI method, fast macromolecular proton fraction (MPF) mapping demonstrated a promise as a myelin biomarker in human and animal studies with a particular advantage of ...

journal_title：Scientific reports

authors： Khodanovich MY,Sorokina IV,Glazacheva VY,Akulov AE,Nemirovich-Danchenko NM,Romashchenko AV,Tolstikova TG,Mustafina LR,Yarnykh VL

更新日期：2017-04-24 00:00:00

abstract：:The 2,5-Diketopiperazines (DKPs) constitute a large family of natural products with important biological activities. Bicyclomycin is a clinically-relevant DKP antibiotic that is the first and only member in a class known to target the bacterial transcription termination factor Rho. It derives from cyclo-(L-isoleucyl-L...

journal_title：Scientific reports

authors： Witwinowski J,Moutiez M,Coupet M,Correia I,Belin P,Ruzzini A,Saulnier C,Caraty L,Favry E,Seguin J,Lautru S,Lequin O,Gondry M,Pernodet JL,Darbon E

更新日期：2019-12-27 00:00:00

abstract：:We aimed to explore the effects of type-2 diabetes mellitus (T2DM) and hypoglycemic therapy on the salivary microbiome in periodontitis patients and identify the potential salivary micro-biomarker for the early warning of T2DM. Saliva samples were collected from healthy individuals (Health), periodontitis patients (P)...

journal_title：Scientific reports

authors： Sun X,Li M,Xia L,Fang Z,Yu S,Gao J,Feng Q,Yang P

更新日期：2020-09-21 00:00:00

abstract：:Detection of nitroaromatic explosives with high sensitivity and selectivity is extremely important for civilian and military safety. Here, we report the synthesis and multimodal sensing applications of an emissive alanine based dansyl tagged copolymer P(MMA-co-Dansyl-Ala-HEMA) (DCP), synthesized by RAFT copolymerizati...

journal_title：Scientific reports

authors： Kumar V,Maiti B,Chini MK,De P,Satapathi S

更新日期：2019-05-13 00:00:00

abstract：:Non-forest ecosystems (predominant in semi-arid and arid regions) contribute significantly to the increasing trend and interannual variation of land carbon uptake over the last three decades, yet the mechanisms are poorly understood. By analysing the flux measurements from 23 ecosystems in Australia, we found the the ...

journal_title：Scientific reports

authors： Li L,Wang YP,Beringer J,Shi H,Cleverly J,Cheng L,Eamus D,Huete A,Hutley L,Lu X,Piao S,Zhang L,Zhang Y,Yu Q

更新日期：2017-09-15 00:00:00

abstract：:Figure-ground segregation is the process by which the visual system identifies image elements of figures and segregates them from the background. Previous studies examined figure-ground segregation in the visual cortex of monkeys where figures elicit stronger neuronal responses than backgrounds. It was demonstrated in...

journal_title：Scientific reports

authors： Schnabel UH,Bossens C,Lorteije JAM,Self MW,Op de Beeck H,Roelfsema PR

更新日期：2018-12-12 00:00:00

abstract：:Diabetes is expected to accelerate age-related ganglion cell-inner plexiform layer (GC-IPL) loss, but there is limited information on the rate of reduction in GC-IPL thicknesses. We aimed to evaluate the reduction rate of GC-IPL thickness in diabetic patients, and to compare the rates between patients without and with...

journal_title：Scientific reports

authors： Lim HB,Shin YI,Lee MW,Koo H,Lee WH,Kim JY

更新日期：2020-01-30 00:00:00

abstract：:Airway smooth muscle (ASM) cells exhibit plastic phenotypic behavior marked by reversible modulation and maturation between contractile and proliferative phenotypic states. Integrins are a class of transmembrane proteins that have been implicated as novel therapeutic targets for asthma treatment. We previously showed ...

journal_title：Scientific reports

authors： Teoh CM,Tan SSL,Langenbach SY,Wong AH,Cheong DHJ,Tam JKC,New CS,Tran T

更新日期：2019-07-09 00:00:00

abstract：:Cytotoxic T lymphocyte-associated antigen 4 immunoglobulin fusion protein (CTLA4Ig, abatacept) is a B7/CD28 costimulation inhibitor that can ward off the immune response by preventing the activation of naïve T cells. This therapeutic agent is administered to patients with autoimmune diseases such as rheumatoid arthrit...

journal_title：Scientific reports

authors： Rim YA,Yi H,Kim Y,Park N,Jung H,Kim J,Jung SM,Park SH,Ju JH

更新日期：2014-11-06 00:00:00

abstract：:Adolescent idiopathic scoliosis (AIS) patients have been reported to be taller and more slender than normal controls, suggesting less mechanical stiffness of their trunk and spine. For assessment of mechanical stiffness, to our best knowledge this is the first to study height-width-depth relations at the level of the ...

journal_title：Scientific reports

authors： Chen H,Schlösser TPC,Brink RC,Colo D,van Stralen M,Shi L,Chu WCW,Heng PA,Castelein RM,Cheng JCY

更新日期：2017-04-18 00:00:00

abstract：:Basal-like breast cancer (BLBC) is associated with a poor clinical outcome due to the few treatment options and absence of effective targeted agents. Here, we show that malic enzyme 1 (ME1) is dramatically upregulated in BLBC due to ME1 copy number amplification. ME1 expression increases glucose uptake and lactate pro...

journal_title：Scientific reports

authors： Liao R,Ren G,Liu H,Chen X,Cao Q,Wu X,Li J,Dong C

更新日期：2018-11-13 00:00:00

abstract：:Recent discoveries have highlighted the novel metabolic functions of adipose tissue in enhancing hypermetabolism after trauma. As the exact function and expression profiles of serum lipids and free fatty acids (FFA) are essentially unknown, we determined the lipidomic expression profile after burn in correlation to cl...

journal_title：Scientific reports

authors： Qi P,Abdullahi A,Stanojcic M,Patsouris D,Jeschke MG

更新日期：2016-12-16 00:00:00

abstract：:Three dimensional hierarchical nanostructures have attracted great attention for electrochemical energy storage applications. In this work, self-supported TiO2@Ni(OH)2 core-shell nanowire arrays are prepared on carbon fiber paper via the combination of hydrothermal synthesis and chemical bath deposition. In this core-...

journal_title：Scientific reports

authors： Ke Q,Zheng M,Liu H,Guan C,Mao L,Wang J

更新日期：2015-09-10 00:00:00

abstract：:We investigated the effect of the crude herbal extract from Uncaria tomentosa (UT) on non-alcoholic fatty liver disease (NAFLD) in two models of obesity: high fat diet (HFD) and genetically obese (ob/ob) mice. Both obese mouse models were insulin resistant and exhibited an abundance of lipid droplets in the hepatocyte...

journal_title：Scientific reports

authors： Araujo LCC,Feitosa KB,Murata GM,Furigo IC,Teixeira SA,Lucena CF,Ribeiro LM,Muscará MN,Costa SKP,Donato J Jr,Bordin S,Curi R,Carvalho CRO

更新日期：2018-07-20 00:00:00

abstract：:Pinellia (Pinellia ternata (Thunb.) Breit.), as important medicinal plant, has been used to treat various ailments for a long time. The sixteen ploid plant (2n = 16 * 13 = 208) Pinellia T2Plus line was obtained from an octoploid (2n = 8 * 13 = 104) T2 line by chromosome-doubling technique. Compared with T2 line, the c...

journal_title：Scientific reports

authors： Lu J,Liu JN,Sarsaiya S,Duns GJ,Han J,Jin L,Chen J

更新日期：2020-03-12 00:00:00

abstract：:Here, we report a newly designed knee plug to be used in the 3rd generation of Autologous Chondrocyte Implantation (ACI) in order to heal the damaged knee cartilage. It is composed of three components: The first component (Bone Portion) is a 3D printed hard scaffold with large pores (~ 850 µm), made by hydroxyapatite ...

journal_title：Scientific reports

authors： Tayebi L,Cui Z,Ye H

更新日期：2020-10-12 00:00:00

abstract：:Solid solutions of Zr(Mo,W)2O7(OH,Cl)2∙2H2O with a preset ratio of components were prepared by a hydrothermal method. The chemical composition of the solutions was determined by energy dispersive X-ray spectroscopy (EDX). For all the samples of ZrMoxW2-xO7(OH,Cl)2∙2H2O (x = 0.0, 0.2, 0.4, 0.6, 0.8, 1.0, 1.2, 1.4, 1.6,...

journal_title：Scientific reports

authors： Petrushina MY,Dedova ES,Filatov EY,Plyusnin PE,Korenev SV,Kulkov SN,Derevyannikova EA,Sharafutdinov MR,Gubanov AI

更新日期：2018-03-28 00:00:00

abstract：:In this paper, a multi-band metal-insulator-metal (MIM) perfect absorber with refractive index sensing capability has been investigated in near-infrared region. The proposed structure has been studied for biomedical applications such as detection of solution of glucose in water, diagnosis of different stages of malari...

journal_title：Scientific reports

authors： Nejat M,Nozhat N

更新日期：2020-04-14 00:00:00

abstract：:Intravitreal anti-vascular endothelial growth factor (VEGF) agents have revolutionized the treatment of retinopathy of prematurity (ROP); however, there are concerns regarding the potential systemic complications caused by those treatments. This study aimed to determine the serum concentrations of cytokines in infants...

journal_title：Scientific reports

authors： Cheng Y,Zhu X,Linghu D,Xu Y,Liang J

更新日期：2020-07-29 00:00:00

abstract：:Measuring the Parathyroid hormone (PTH) levels assists in the investigation and management of patients with parathyroid disorders. Rapid PTH monitoring is a valid tool for accurate assessment intraoperatively. Rapid Electro-Analytical Device (READ) is a point-of-care device that uses impedance change between target an...

journal_title：Scientific reports

authors： Tanak AS,Muthukumar S,Hashim IA,Prasad S

更新日期：2020-11-02 00:00:00

abstract：:Choosing an option increases a person's preference for that option. This phenomenon, called choice-based learning (CBL), has been investigated separately in the contexts of internally guided decision-making (IDM, e.g., preference judgment), for which no objectively correct answer exists, and externally guided decision...

journal_title：Scientific reports

authors： Nakao T,Kanayama N,Katahira K,Odani M,Ito Y,Hirata Y,Nasuno R,Ozaki H,Hiramoto R,Miyatani M,Northoff G

更新日期：2016-08-31 00:00:00

abstract：:In many human cancers, including hepatocellular carcinoma (HCC), high density of infiltrating tumor-associated macrophages (TAM) is associated with poor prognosis. Most TAMs express a M2 phenotype subsequently supporting tumor growth. How tumor cells polarize these TAMs to a pro-tumor M2 phenotype is still poorly unde...

journal_title：Scientific reports

authors： Shiau DJ,Kuo WT,Davuluri GVN,Shieh CC,Tsai PJ,Chen CC,Lin YS,Wu YZ,Hsiao YP,Chang CP

更新日期：2020-08-12 00:00:00

abstract：:Deconvolution is widely used to improve the contrast and clarity of a 3D focal stack collected using a fluorescence microscope. But despite being extensively studied, deconvolution algorithms can introduce reconstruction artifacts when their underlying noise models or priors are violated, such as when imaging biologic...

journal_title：Scientific reports

authors： Ikoma H,Broxton M,Kudo T,Wetzstein G

更新日期：2018-07-31 00:00:00

abstract：:MicroRNAs (miRNAs) are noncoding RNAs which control gene expression by the suppression of translation or the degradation of mRNAs. Dre-miR-21 (miR-21) has been reported to impact cardiac valvulogenesis in zebrafish embryos. However, the target genes of miR-21 are still largely unknown. Here a tandem isobaric mass tag ...

journal_title：Scientific reports

authors： Wu Y,Lou QY,Ge F,Xiong Q

更新日期：2017-06-22 00:00:00