Phenotypic and Transcriptomic Analysis of Two Pinellia ternata Varieties T2 line and T2Plus line.

abstract：:Mitofusins are large transmembrane GTPases of the dynamin-related protein family, and are required for the tethering and fusion of mitochondrial outer membranes. Their full-length structures remain unknown, which is a limiting factor in the study of outer membrane fusion. We investigated the structure and dynamics of ...

journal_title：Scientific reports

authors： De Vecchis D,Cavellini L,Baaden M,Hénin J,Cohen MM,Taly A

更新日期：2017-08-31 00:00:00

abstract：:Cancer stem-like cells (CSCs) play a key role in maintaining the aggressiveness of hepatocellular carcinoma (HCC), but the cell-biological regulation of CSCs is unclear. In the study, we report that thyroid hormone (TH) promotes cell self-renewal in HCC cells. TH also increases the percentage of CD90 + HCC cells and p...

journal_title：Scientific reports

authors： Wang T,Xia L,Ma S,Qi X,Li Q,Xia Y,Tang X,Cui D,Wang Z,Chi J,Li P,Feng YX,Xia Q,Zhai B

更新日期：2016-05-12 00:00:00

abstract：:Modeling the dynamic nature of protein-ligand binding with atomistic simulations is one of the main challenges in computational biophysics, with important implications in the drug design process. Although in the past few years hardware and software advances have significantly revamped the use of molecular simulations,...

journal_title：Scientific reports

authors： Lecina D,Gilabert JF,Guallar V

更新日期：2017-08-16 00:00:00

abstract：:Tilapias (family Cichlidae) are of importance in aquaculture and fisheries. Hybridisation and introgression are common within tilapia genera but are difficult to analyse due to limited numbers of species-specific genetic markers. We tested the potential of double digested restriction-site associated DNA (ddRAD) sequen...

journal_title：Scientific reports

authors： Syaifudin M,Bekaert M,Taggart JB,Bartie KL,Wehner S,Palaiokostas C,Khan MGQ,Selly SC,Hulata G,D'Cotta H,Baroiller JF,McAndrew BJ,Penman DJ

更新日期：2019-09-10 00:00:00

abstract：:Rapid histopathological evaluation of fresh, unfixed human tissue using optical sectioning microscopy would have applications to intraoperative surgical margin assessment. Microscopy with ultraviolet surface excitation (MUSE) is a low-cost optical sectioning technique using ultraviolet illumination which limits fluore...

journal_title：Scientific reports

authors： Yoshitake T,Giacomelli MG,Quintana LM,Vardeh H,Cahill LC,Faulkner-Jones BE,Connolly JL,Do D,Fujimoto JG

更新日期：2018-03-14 00:00:00

abstract：:In the current research, to find if the combination of chitosan nerve conduits seeded with autologous bone marrow mononuclear cells (BM-MNCs) can be used to bridge 30 mm long peroneal nerve defects in goats, 15 animals were separated into BM-MNC group (n = 5), vehicle group (n = 5), and autologous nerve graft group (n...

journal_title：Scientific reports

authors： Muheremu A,Chen L,Wang X,Wei Y,Gong K,Ao Q

更新日期：2017-03-13 00:00:00

abstract：:Coronin7 (CRN7) stabilizes F-actin and is a regulator of processes associated with the actin cytoskeleton. Its loss leads to defects in phagocytosis, motility and development. It harbors a CRIB (Cdc42- and Rac-interactive binding) domain in each of its WD repeat domains which bind to Rac GTPases preferably in their GD...

journal_title：Scientific reports

authors： Swaminathan K,Stumpf M,Müller R,Horn AC,Schmidbauer J,Eichinger L,Müller-Taubenberger A,Faix J,Noegel AA

更新日期：2015-09-28 00:00:00

abstract：:Body contouring achieved via subcutaneous adipose tissue reduction has notably advanced over the past century, from suction assisted lipectomy to techniques with reduced degrees of invasiveness including laser, radiofrequency, high frequency focused ultrasound, cryolipolysis, and drug-based injection approaches. These...

journal_title：Scientific reports

authors： Pham TT,Stokolosa AM,Borden PA,Hansen KD,Hong EM,Krasieva TB,Sivoraphonh RH,Moy WJ,Heidari AE,Lee LH,Kim EH,Sun CH,Jia W,Mo J-,Kim S,Hill MG,Wong BJF

更新日期：2020-11-27 00:00:00

abstract：:We aimed to report patients' survival after surgical resection of eSCC and to ascertain the clinical, imaging, and pathological factors related to patient prognosis. This retrospective study included 435 patients with eSCC of

journal_title：Scientific reports

authors： Jeong DY,Lee KS,Choi JY,Chung MJ,Min YW,Kim HK,Zo JI,Shim YM,Sun JM

更新日期：2020-03-19 00:00:00

abstract：:Photomechanical nanocomposites embedded with light-absorbing nanoparticles show promising applications in photoresponsive actuations. Near infrared (nIR)-responsive nanocomposites based photomechanical soft actuators can offer lightweight functional and underexploited entry into soft robotics, active optics, drug deli...

journal_title：Scientific reports

authors： Niu D,Jiang W,Liu H,Zhao T,Lei B,Li Y,Yin L,Shi Y,Chen B,Lu B

更新日期：2016-06-06 00:00:00

abstract：:Flagellin is amongst the most abundant proteins in flagellated bacterial species and constitutes the major building block of the flagellar filament. The proteins FliW and FliS serve in the post-transcriptional control of flagellin and guide the protein to the flagellar type III secretion system (fT3SS), respectively. ...

journal_title：Scientific reports

authors： Altegoer F,Mukherjee S,Steinchen W,Bedrunka P,Linne U,Kearns DB,Bange G

更新日期：2018-08-01 00:00:00

abstract：:The biological functions of nitric oxide (NO) depend on its concentration, and excessive levels of NO induce various harmful situations known as nitrosative stress. Therefore, organisms possess many kinds of strategies to regulate the intracellular NO concentration and/or to detoxify excess NO. Here, we used genetic s...

journal_title：Scientific reports

authors： Anam K,Nasuno R,Takagi H

更新日期：2020-04-07 00:00:00

abstract：:Insulin gene mutations have been identified to cause monogenic diabetes, and most of which developed permanent neonatal diabetes at young ages before 6 months of age in humans. To establish an animal model of permanent diabetes, we performed genome editing using the CRISPR/Cas9 system. We generated a novel Kuma mutant...

journal_title：Scientific reports

authors： Sakano D,Inoue A,Enomoto T,Imasaka M,Okada S,Yokota M,Koike M,Araki K,Kume S

更新日期：2020-07-22 00:00:00

abstract：:Perturbations in lipid metabolic pathways to meet the bioenergetic and biosynthetic requirements is a principal characteristic of cancer cells. Sphingolipids (SPLs) are the largest class of bioactive lipids associated to various aspects of tumorigenesis and have been extensively studied in cancer cell lines and experi...

journal_title：Scientific reports

authors： Bhadwal P,Dahiya D,Shinde D,Vaiphei K,Math RGH,Randhawa V,Agnihotri N

更新日期：2020-03-13 00:00:00

abstract：:By applying a slow curing process, we show that biomolecules can be incorporated via a simple process as liquid stable phases inside a polydimethylsiloxane (PDMS) matrix. The process is carried out under mild conditions with regards to temperature, pH and relative humidity, and is thus suitable for application to biol...

journal_title：Scientific reports

authors： Faccio G,Cont A,Mailand E,Zare-Eelanjegh E,Innocenti Malini R,Maniura-Weber K,Rossi RM,Spano F

更新日期：2019-11-26 00:00:00

abstract：:Loss of seed shattering has been regarded as a key step during crop domestication. Mutagenesis contributes to the development of novel crop cultivars with a desired seed-shattering habit in a relatively short period of time, but also to uncovering the genetic architecture of seed shattering. 'Minamiyutaka', a non-shat...

journal_title：Scientific reports

authors： Li F,Komatsu A,Ohtake M,Eun H,Shimizu A,Kato H

更新日期：2020-09-10 00:00:00

abstract：:Electrical stimulation is a common adjunct used to promote bone healing; its efficacy, however, remains uncertain. We conducted a meta-analysis of randomized sham-controlled trials to establish the efficacy of electrical stimulation for bone healing. We identified all trials randomizing patients to electrical or sham ...

journal_title：Scientific reports

authors： Aleem IS,Aleem I,Evaniew N,Busse JW,Yaszemski M,Agarwal A,Einhorn T,Bhandari M

更新日期：2016-08-19 00:00:00

abstract：:We report on the magnetic field control of a bipolar resistive switching in Ag/TiO2/FTO based resistive random access memory device through I-V characteristics. Essentially, in the presence of magnetic field and in the low resistance state, an abrupt change in the resistance of the device demands higher voltage, hinti...

journal_title：Scientific reports

authors： Sahu DP,Jammalamadaka SN

更新日期：2017-12-08 00:00:00

abstract：:Cenozoic ectothermic continental tetrapods (amphibians and reptiles) have not been documented previously from Antarctica, in contrast to all other continents. Here we report a fossil ilium and an ornamented skull bone that can be attributed to the Recent, South American, anuran family Calyptocephalellidae or helmeted ...

journal_title：Scientific reports

authors： Mörs T,Reguero M,Vasilyan D

更新日期：2020-04-23 00:00:00

abstract：:A cerebral aneurysm occurs as a result of a weakened blood vessel, which allows blood to flow into a sac or a ballooned section. Recent advancement shows that a new device, 'flow-diverter', can divert blood flow away from the aneurysm sac. People found that a flow-diverter based on thin film nitinol (TFN), works very ...

journal_title：Scientific reports

authors： Chen Y,Howe C,Lee Y,Cheon S,Yeo WH,Chun Y

更新日期：2016-03-24 00:00:00

abstract：:Selenium and selenium nanoparticles (SeNPs) are extensively used in biomedicine, electronics and some other industrial applications. The bioproduction of SeNPs is gaining interest as a green method to manufacture these biotechnologically relevant products. Several microorganisms have been used for the production of Se...

journal_title：Scientific reports

authors： Fernández-Llamosas H,Castro L,Blázquez ML,Díaz E,Carmona M

更新日期：2017-11-22 00:00:00

abstract：:Changes in immune and coagulation systems and possible viral spread through the blood-brain barrier have been described in SARS-CoV-2 infection. In this study, we evaluated the possible retinal involvement and ocular findings in severe COVID-19 pneumonia patients. A cross-sectional study was conducted on 46 patients a...

journal_title：Scientific reports

authors： Pirraglia MP,Ceccarelli G,Cerini A,Visioli G,d'Ettorre G,Mastroianni CM,Pugliese F,Lambiase A,Gharbiya M

更新日期：2020-10-15 00:00:00

abstract：:We have identified a gene (PpSAP1) of Prunus persica coding for a stress-associated protein (SAP) containing Zn-finger domains A20 and AN1. SAPs have been described as regulators of the abiotic stress response in plant species, emerging as potential candidates for improvement of stress tolerance in plants. PpSAP1 was ...

journal_title：Scientific reports

authors： Lloret A,Conejero A,Leida C,Petri C,Gil-Muñoz F,Burgos L,Badenes ML,Ríos G

更新日期：2017-03-23 00:00:00

abstract：:Locusts have excellent jumping and kicking abilities to survive in nature, which are achieved through the energy storage and release processes occurring in cuticles, especially in the semi-lunar processes (SLP) at the femorotibial joints. As yet, however, the strain energy-storage mechanisms of the SLP cuticles remain...

journal_title：Scientific reports

authors： Wan C,Hao Z,Feng X

更新日期：2016-10-17 00:00:00

abstract：:To construct a machine learning algorithm model of lymph node metastasis (LNM) in patients with poorly differentiated-type intramucosal gastric cancer. 1169 patients with postoperative gastric cancer were divided into a training group and a test group at a ratio of 7:3. The model for lymph node metastasis was establis...

journal_title：Scientific reports

authors： Zhou CM,Wang Y,Ye HT,Yan S,Ji M,Liu P,Yang JJ

更新日期：2021-01-14 00:00:00

abstract：:Orthogonal aminoacyl-tRNA synthetase/tRNA pairs have emerged as powerful means of site-specifically introducing non-standard amino acids into proteins in vivo. Using amino acids with crosslinking moieties this method allows the identification of transient protein-protein interactions. Here we have introduced a previou...

journal_title：Scientific reports

authors： Huot JL,Shikha S,Schneider A

更新日期：2019-07-25 00:00:00

abstract：:Ionotropic glutamate receptors (iGluRs) are responsible for most of the fast excitatory communication between neurons in our brain. The GluD2 receptor is a puzzling member of the iGluR family: It is involved in synaptic plasticity, plays a role in human diseases, e.g. ataxia, binds glycine and D-serine with low affini...

journal_title：Scientific reports

authors： Tapken D,Steffensen TB,Leth R,Kristensen LB,Gerbola A,Gajhede M,Jørgensen FS,Olsen L,Kastrup JS

更新日期：2017-04-07 00:00:00

abstract：:We successfully realised plasmon-driven selective reduction reactions of 2-amino-5-nitrobenzenethiol (2A-5-NBT) to 3,3'-dimercapto-4,4'-diaminoazobenzene , an azobenzene derivative, using surface-enhanced Raman scattering (SERS) spectroscopy, and supported by the theoretical calculations. The SERS spectra demonstrated...

journal_title：Scientific reports

authors： Ding Q,Chen M,Li Y,Sun M

更新日期：2015-06-01 00:00:00

abstract：:Patients with liver cirrhosis are susceptible to infections with high short-term mortalities. One CD97-related EGF-TM7 molecule, EMR2 (EGF-like molecule containing mucin-like hormone receptor 2), had been shown to regulate human neutrophil function, potentiate systemic inflammation. Nevertheless, EMR2 could also suppr...

journal_title：Scientific reports

authors： Huang CH,Jeng WJ,Ho YP,Teng W,Hsieh YC,Chen WT,Chen YC,Lin HH,Sheen IS,Lin CY

更新日期：2016-12-01 00:00:00

abstract：:Copper ions play a vital role in a variety of fundamental physiological processes not only in human beings and plants, but also for extensive insects and microorganisms. In this paper, a novel water-soluble ruthenium(II) complex as a turn-on copper(II) ions luminescent sensor based on o-(phenylazo)aniline was designed...

journal_title：Scientific reports

authors： Zhang Y,Liu Z,Yang K,Zhang Y,Xu Y,Li H,Wang C,Lu A,Sun S

更新日期：2015-02-02 00:00:00