当前位置： SCI文献检索 > Scientific Reports期刊下所有文献 > Figure-ground perception in the awake mouse and neuronal activity elicited by figure-ground stimuli in primary visual cortex.

Figure-ground perception in the awake mouse and neuronal activity elicited by figure-ground stimuli in primary visual cortex.

Abstract：

:Figure-ground segregation is the process by which the visual system identifies image elements of figures and segregates them from the background. Previous studies examined figure-ground segregation in the visual cortex of monkeys where figures elicit stronger neuronal responses than backgrounds. It was demonstrated in anesthetized mice that neurons in the primary visual cortex (V1) of mice are sensitive to orientation contrast, but it is unknown whether mice can perceptually segregate figures from a background. Here, we examined figure-ground perception of mice and found that mice can detect figures defined by an orientation that differs from the background while the figure size, position or phase varied. Electrophysiological recordings in V1 of awake mice revealed that the responses elicited by figures were stronger than those elicited by the background and even stronger at the edge between figure and background. A figural response could even be evoked in the absence of a stimulus in the V1 receptive field. Current-source-density analysis suggested that the extra activity was caused by synaptic inputs into layer 2/3. We conclude that the neuronal mechanisms of figure-ground segregation in mice are similar to those in primates, enabling investigation with the powerful techniques for circuit analysis now available in mice.

journal_name

Sci Rep

journal_title

Scientific reports

authors

Schnabel UH,Bossens C,Lorteije JAM,Self MW,Op de Beeck H,Roelfsema PR

doi

10.1038/s41598-018-36087-8

subject

Has Abstract

pub_date

2018-12-12 00:00:00

pages

17800

issue

1

issn

2045-2322

pii

10.1038/s41598-018-36087-8

journal_volume

8

pub_type

杂志文章

相关文献

Scientific Reports文献大全
  • Forced transport of self-propelled particles in a two-dimensional separate channel.

    abstract：:Transport of self-propelled particles in a two-dimensional (2D) separate channel is investigated in the presence of the combined forces. By applying an ac force, the particles will be trapped by the separate walls. A dc force produces the asymmetry of the system and induces the longitudinal directed transport. Due to ...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/srep24001

    authors： Wu JC,Ai BQ

    更新日期：2016-04-01 00:00:00

  • Control of decoherence with no control.

    abstract：:A common philosophy in control theory is the control of disorder by order. Control of decoherence is no exception; strategies aimed at suppressing quantum decoherence adopt this point of view. Here we predict an anomalous phenomenon in open quantum systems-control of disorder by (even more) disorder. It is shown that ...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/srep02746

    authors： Jing J,Wu LA

    更新日期：2013-09-25 00:00:00

  • Berberine improved experimental chronic colitis by regulating interferon-γ- and IL-17A-producing lamina propria CD4+ T cells through AMPK activation.

    abstract：:The herbal medicine berberine (BBR) has been recently shown to be an AMP-activated protein kinase (AMPK) productive activator with various properties that induce anti-inflammatory responses. We investigated the effects of BBR on the mechanisms of mucosal CD4+T cell activation in vitro and on the inflammatory responses...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-019-48331-w

    authors： Takahara M,Takaki A,Hiraoka S,Adachi T,Shimomura Y,Matsushita H,Nguyen TTT,Koike K,Ikeda A,Takashima S,Yamasaki Y,Inokuchi T,Kinugasa H,Sugihara Y,Harada K,Eikawa S,Morita H,Udono H,Okada H

    更新日期：2019-08-15 00:00:00

  • Low immunogenic endothelial cells endothelialize the Left Ventricular Assist Device.

    abstract：:Low haemocompatibility of left ventricular assist devices (LVAD) surfaces necessitates anticoagulative therapy. Endothelial cell (EC) seeding can support haemocompatibility, however, the availability of autologous ECs is limited. In contrast, allogeneic ECs are readily available in sufficient quantity, but HLA dispari...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-019-47780-7

    authors： Figueiredo C,Eicke D,Yuzefovych Y,Avsar M,Hanke JS,Pflaum M,Schmitto JD,Blasczyk R,Haverich A,Wiegmann B

    更新日期：2019-08-05 00:00:00

  • Out-coupling of Longitudinal Photoacoustic Pulses by Mitigating the Phase Cancellation.

    abstract：:Waves of any kinds, including sound waves and light waves, can interfere constructively or destructively when they are overlapped, allowing for myriad applications. However, unlike continuous waves of a single frequency, interference of photoacoustic pulses is often overlooked because of their broadband characteristic...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/srep21511

    authors： Lee T,Li Q,Guo LJ

    更新日期：2016-02-12 00:00:00

  • Experimental Realization of Extreme Heat Flux Concentration with Easy-to-Make Thermal Metamaterials.

    abstract：:The ability to harvest thermal energy and manipulate heat fluxes has recently attracted a great deal of research interest because this is critical to achieve efficient solar-to-thermal energy conversion in the technology of concentrated solar thermal collectors. Thermal metamaterials with engineered thermal conduction...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/srep11552

    authors： Chen F,Lei DY

    更新日期：2015-06-25 00:00:00

  • Genomic Analyses of Breast Cancer Progression Reveal Distinct Routes of Metastasis Emergence.

    abstract：:A main controversy in cancer research is whether metastatic abilities are present in the most advanced clone of the primary tumor or result from independently acquired aberrations in early disseminated cancer cells as suggested by the linear and the parallel progression models, respectively. The genetic concordance be...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/srep43813

    authors： Krøigård AB,Larsen MJ,Brasch-Andersen C,Lænkholm AV,Knoop AS,Jensen JD,Bak M,Mollenhauer J,Thomassen M,Kruse TA

    更新日期：2017-03-09 00:00:00

  • Multiple sclerosis drug FTY-720 toxicity is mediated by the heterotypic fusion of organelles in neuroendocrine cells.

    abstract：:FTY-720 (Fingolimod) was one of the first compounds authorized for the treatment of multiple sclerosis. Among its other activities, this sphingosine analogue enhances exocytosis in neuroendocrine chromaffin cells, altering the quantal release of catecholamines. Surprisingly, the size of chromaffin granules is reduced ...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-019-55106-w

    authors： Gimenez-Molina Y,García-Martínez V,Villanueva J,Davletov B,Gutiérrez LM

    更新日期：2019-12-05 00:00:00

  • The evolution of interdisciplinarity in physics research.

    abstract：:Science, being a social enterprise, is subject to fragmentation into groups that focus on specialized areas or topics. Often new advances occur through cross-fertilization of ideas between sub-fields that otherwise have little overlap as they study dissimilar phenomena using different techniques. Thus to explore the n...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/srep00551

    authors： Pan RK,Sinha S,Kaski K,Saramäki J

    更新日期：2012-01-01 00:00:00

  • Cell-based interferon gene therapy using proliferation-controllable, interferon-releasing mesenchymal stem cells.

    abstract：:An important safety concern on cell-based gene therapy is that few methods have been available to control the proliferation and functioning of therapeutic protein-expressing cells after transplantation. We previously reported that the proliferation and functioning of the cells transfected with herpes simplex virus thy...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-019-55269-6

    authors： Tsujimura M,Kusamori K,Katsumi H,Sakane T,Yamamoto A,Nishikawa M

    更新日期：2019-12-11 00:00:00

  • Decoherence and control of a qubit in spin baths: an exact master equation study.

    abstract：:In spin-based nanosystems for quantum information processing, electron spin qubits are subject to decoherence due to their interactions with nuclear spin environments. In this paper, we present an exact master equation for a central spin-1/2 system in time-dependent external fields and coupled to a spin-half bath in t...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-018-19977-9

    authors： Jing J,Wu LA

    更新日期：2018-01-24 00:00:00

  • Impact of the secretome of activated pancreatic stellate cells on growth and differentiation of pancreatic tumour cells.

    abstract：:Pancreatic ductal adenocarcinoma (PDAC) exists in a complex desmoplastic microenvironment. As part of it, pancreatic stellate cells (PSCs) provide a fibrotic niche, stimulated by a dynamic communication between activated PSCs and tumour cells. Investigating how PSCs contribute to tumour development and for identifying...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-019-41740-x

    authors： Marzoq AJ,Mustafa SA,Heidrich L,Hoheisel JD,Alhamdani MSS

    更新日期：2019-03-28 00:00:00

  • High performance C/S composite cathodes with conventional carbonate-based electrolytes in Li-S battery.

    abstract：:High stable C/S composites are fabricated by a novel high-temperature sulfur infusion into micro-mesoporous carbon method following with solvent cleaning treatment. The C/S composite cathodes show high Coulombic efficiency, long cycling stability and good rate capability in the electrolyte of 1.0 M LiPF6 + EC/DEC (1:1...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/srep04842

    authors： Zheng S,Han P,Han Z,Zhang H,Tang Z,Yang J

    更新日期：2014-04-29 00:00:00

  • M2BP inhibits HIV-1 virion production in a vimentin filaments-dependent manner.

    abstract：:M2BP (also called 90K) is an interferon-stimulated gene product that is upregulated in HIV-1 infection. A recent study revealed that M2BP reduces the infectivity of HIV-1 by inhibiting the processing of the viral envelope protein. Here we report that in addition to reducing viral infectivity, M2BP inhibits HIV-1 virio...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/srep32736

    authors： Wang Q,Zhang X,Han Y,Wang X,Gao G

    更新日期：2016-09-08 00:00:00

  • Highly variable COI haplotype diversity between three species of invasive pest fruit fly reflects remarkably incongruent demographic histories.

    abstract：:Distance decay principles predict that species with larger geographic ranges would have greater intraspecific genetic diversity than more restricted species. However, invasive pest species may not follow this prediction, with confounding implications for tracking phenomena including original ranges, invasion pathways ...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-020-63973-x

    authors： Doorenweerd C,San Jose M,Barr N,Leblanc L,Rubinoff D

    更新日期：2020-04-23 00:00:00

  • Persistence of a stage-structured food-web.

    abstract：:Contrary to a theoretical prediction, natural communities comprise many interacting species, thereby developing complex ecosystems. Earlier theoretical studies assumed that each component species within an ecological network has a simple life history, despite the fact that the interaction partners of many species, suc...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-017-11686-z

    authors： Mougi A

    更新日期：2017-09-08 00:00:00

  • Passive acoustic listening stations (PALS) show rapid onset of ecological effects of harmful algal blooms in real time.

    abstract：:Monitoring ecological changes in marine ecosystems is expensive and time-consuming. Passive acoustic methods provide continuous monitoring of soniferous species, are relatively inexpensive, and can be integrated into a larger network to provide enhanced spatial and temporal coverage of ecological events. We demonstrat...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-020-74647-z

    authors： Rycyk AM,Tyson Moore RB,Wells RS,McHugh KA,Berens McCabe EJ,Mann DA

    更新日期：2020-10-20 00:00:00

  • Publisher Correction: A comparative analysis using flowmeter, laser-Doppler spectrophotometry, and indocyanine green-videoangiography for detection of vascular stenosis in free flaps.

    abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

    journal_title：Scientific reports

    pub_type： 已发布勘误

    doi：10.1038/s41598-020-60910-w

    authors： Mücke T,Hapfelmeier A,Schmidt LH,Fichter AM,Kanatas A,Wolff KD,Ritschl LM

    更新日期：2020-02-28 00:00:00

  • Regulation of Irregular Neuronal Firing by Autaptic Transmission.

    abstract：:The importance of self-feedback autaptic transmission in modulating spike-time irregularity is still poorly understood. By using a biophysical model that incorporates autaptic coupling, we here show that self-innervation of neurons participates in the modulation of irregular neuronal firing, primarily by regulating th...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/srep26096

    authors： Guo D,Wu S,Chen M,Perc M,Zhang Y,Ma J,Cui Y,Xu P,Xia Y,Yao D

    更新日期：2016-05-17 00:00:00

  • Hop flower extracts mitigate retinal ganglion cell degeneration in a glaucoma mouse model.

    abstract：:In glaucoma, retinal ganglion cells degenerate progressively, leading to visual field loss and blindness. Presently, the only treatment strategy for glaucoma is lowering the intraocular pressure. However, there are cases in which patients develop progressive visual field loss even though their intraocular pressures ar...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-020-78731-2

    authors： Hasegawa T,Ikeda HO,Iwai S,Sasaoka N,Kakizuka A,Tsujikawa A

    更新日期：2020-12-10 00:00:00

  • Ferroelectric Tunneling Junctions Based on Aluminum Oxide/ Zirconium-Doped Hafnium Oxide for Neuromorphic Computing.

    abstract：:Ferroelectric tunneling junctions (FTJs) with tunable tunneling electroresistance (TER) are promising for many emerging applications, including non-volatile memories and neurosynaptic computing. One of the key challenges in FTJs is the balance between the polarization value and the tunneling current. In order to achie...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-019-56816-x

    authors： Ryu H,Wu H,Rao F,Zhu W

    更新日期：2019-12-31 00:00:00

  • mTORC1 activity is essential for erythropoiesis and B cell lineage commitment.

    abstract：:Mechanistic target of rapamycin (mTOR) is a serine/threonine protein kinase that mediates phosphoinositide-3-kinase (PI3K)/AKT signalling. This pathway is involved in a plethora of cellular functions including protein and lipid synthesis, cell migration, cell proliferation and apoptosis. In this study, we proposed to ...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-019-53141-1

    authors： Malik N,Dunn KM,Cassels J,Hay J,Estell C,Sansom OJ,Michie AM

    更新日期：2019-11-15 00:00:00

  • Embryonic/fetal mortality and intrauterine growth restriction is not exclusive to the CBA/J sub-strain in the CBA × DBA model.

    abstract：:Inbred strains of mice are powerful models for understanding human pregnancy complications. For example, the exclusive mating of CBA/J females to DBA/2J males increases fetal resorption to 20-35% with an associated decline in placentation and maintenance of maternal Th1 immunity. More recently other complications of p...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/srep35138

    authors： McKelvey KJ,Yenson VM,Ashton AW,Morris JM,McCracken SA

    更新日期：2016-10-21 00:00:00

  • Positive/Negative Allosteric Modulation Switching in an Umami Taste Receptor (T1R1/T1R3) by a Natural Flavor Compound, Methional.

    abstract：:Taste is a vital sensation for vertebrates, enabling the detection of nutritionally important substances or potential toxins. A heteromeric complex of two class C GPCRs, T1R1 and T1R3, was identified as the umami (savory) taste receptor. Amino acids and 5'-ribonucleotides are well known to be natural ligands for human...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-018-30315-x

    authors： Toda Y,Nakagita T,Hirokawa T,Yamashita Y,Nakajima A,Narukawa M,Ishimaru Y,Uchida R,Misaka T

    更新日期：2018-08-07 00:00:00

  • Water walking as a new mode of free surface skipping.

    abstract：:Deformable elastomeric spheres are evaluated experimentally as they skip multiple times over a lake surface. Some spheres are embedded with small inertial measurement units to measure the acceleration experienced during water surface impact. A model for multiple impact events shows good agreement between measured acce...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-019-42453-x

    authors： Hurd RC,Belden J,Bower AF,Holekamp S,Jandron MA,Truscott TT

    更新日期：2019-04-15 00:00:00

  • Effects of Chikungunya virus immunity on Mayaro virus disease and epidemic potential.

    abstract：:Mayaro virus (MAYV) causes an acute febrile illness similar to that produced by chikungunya virus (CHIKV), an evolutionary relative in the Semliki Forest virus complex of alphaviruses. MAYV emergence is typically sporadic, but recent isolations and outbreaks indicate that the virus remains a public health concern. Giv...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-019-56551-3

    authors： Webb EM,Azar SR,Haller SL,Langsjoen RM,Cuthbert CE,Ramjag AT,Luo H,Plante K,Wang T,Simmons G,Carrington CVF,Weaver SC,Rossi SL,Auguste AJ

    更新日期：2019-12-31 00:00:00

  • An oxytocin-dependent social interaction between larvae and adult C. elegans.

    abstract：:Oxytocin has a conserved role in regulating animal social behaviour including parental-offspring interactions. Recently an oxytocin-like neuropeptide, nematocin, and its cognate receptors have been identified in the nematode Caenorhabditis elegans. We provide evidence for a pheromone signal produced by C. elegans larv...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-017-09350-7

    authors： Scott E,Hudson A,Feist E,Calahorro F,Dillon J,de Freitas R,Wand M,Schoofs L,O'Connor V,Holden-Dye L

    更新日期：2017-08-31 00:00:00

  • Publisher Correction: Hyperpolarized [1-13C]-acetate Renal Metabolic Clearance Rate Mapping.

    abstract：:A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper. ...

    journal_title：Scientific reports

    pub_type： 已发布勘误

    doi：10.1038/s41598-018-29057-7

    authors： Mikkelsen EFR,Mariager CØ,Nørlinger T,Qi H,Schulte RF,Jakobsen S,Frøkiær J,Pedersen M,Stødkilde-Jørgensen H,Laustsen C

    更新日期：2018-07-20 00:00:00

  • Randomized, Multicenter, Double-Blind Study of the Safety and Efficacy of 1%D-3-Hydroxybutyrate eye drops for Dry Eye Disease.

    abstract：:In a previous study, we demonstrated that topical D-beta-hydroxybutyrate ameliorates corneal epithelial erosion and superficial punctate keratopathy in a rat model of dry eye disease. In the current investigation, we performed a prospective, randomized, multicentre, double-blind, placebo-controlled study to assess the...

    journal_title：Scientific reports

    pub_type： 杂志文章,多中心研究,随机对照试验

    doi：10.1038/srep20855

    authors： Kawakita T,Uchino M,Fukagawa K,Yoshino K,Shimazaki S,Toda I,Tanaka M,Arai H,Sakatani K,Hata S,Okano T,Tsubota K

    更新日期：2016-02-11 00:00:00

  • Protein-bound uremic toxins are associated with cognitive function among patients undergoing maintenance hemodialysis.

    abstract：:Patients with chronic kidney disease have a greater risk of cognitive impairment. Cerebral uremic solute accumulation causes uremic encephalopathy; however, the association of protein-bound uremic toxins on cognitive function remains unclear. The present study aimed to investigate the association of two protein-bound ...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-019-57004-7

    authors： Lin YT,Wu PH,Liang SS,Mubanga M,Yang YH,Hsu YL,Kuo MC,Hwang SJ,Kuo PL

    更新日期：2019-12-31 00:00:00