Abstract:
:An amendment to this paper has been published and can be accessed via a link at the top of the paper.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Baiocchini A,Del Nonno F,Taibi C,Visco-Comandini U,D'Offizi G,Piacentini M,Falasca Ldoi
10.1038/s41598-020-58227-9subject
Has Abstractpub_date
2020-01-24 00:00:00pages
1420issue
1issn
2045-2322pii
10.1038/s41598-020-58227-9journal_volume
10pub_type
已发布勘误abstract::The human pyruvate dehydrogenase complex (PDC) comprises four multidomain components, E1, E3, E2 and an E3-binding protein (E3BP), the latter two forming the core as E2·E3BP sub-complex. Pyruvate flux through PDC is regulated via phosphorylation (inactivation) at E1 by four PDC kinases (PDKs), and reactivation by two ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep42760
更新日期:2017-02-23 00:00:00
abstract::Nitrogen-doped graphene (N-graphene) has attractive properties that has been widely studied over the years. However, its possible formation process still remains unclear. Here, we propose a highly feasible formation mechanism of the graphitic-N doing in thermally treated graphene with ammonia by performing ab initio m...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep23495
更新日期:2016-03-22 00:00:00
abstract::Although extensive studies have focused on the development of acute mountain sickness (AMS), the exact mechanisms of AMS are still obscure. In this study, we used isobaric tags for relative and absolute quantitation (iTRAQ) proteomic analysis to identify novel AMS-associated biomarkers in human plasma. After 9 hours o...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-19818-9
更新日期:2018-01-19 00:00:00
abstract::Traumatic brain injury (TBI) is a frequent cause of chronic headache, fatigue, insomnia, hyperactivity, memory deficits, irritability and posttraumatic stress disorder. Recent evidence suggests beneficial effects of pro-cannabinoid treatments. We assessed in mice levels of endocannabinoids in association with the occu...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-71879-x
更新日期:2020-09-10 00:00:00
abstract::This report investigated dislocation-twin boundary (TB) interactions that cause the TB to disappear and turn into a high-angle grain boundary (GB). The evolution of the microstructural characteristics of Hadfield steel was shown as a function of severe plastic deformation processing time. Sessile Frank partial disloca...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep08981
更新日期:2015-03-11 00:00:00
abstract::Large-scale studies have not been conducted to assess whether serum hypobicarbonatemia increases the risk for kidney function deterioration and mortality among East-Asians. We aimed to determine the association between serum total CO2 (TCO2) concentrations measured at the first outpatient visit and clinical outcomes. ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-021-81332-2
更新日期:2021-01-18 00:00:00
abstract::Maize streak virus disease (MSVD), caused by Maize streak virus (MSV; genus Mastrevirus), is one of the most severe and widespread viral diseases that adversely reduces maize yield and threatens food security in Africa. An effective control and management of MSVD requires robust and sensitive diagnostic tests capable ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-76612-2
更新日期:2020-11-12 00:00:00
abstract::In the present study, we obtained population genetic data and forensic parameters of 30 InDel loci in Chinese Xibe ethnic group from northwestern China and studied the genetic relationships between the studied Xibe group and other reference groups. The observed heterozygosities ranged from 0.1704 at HLD118 locus to 0....
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep08260
更新日期:2015-02-05 00:00:00
abstract::Neuropathic pain is characterized by an uncertain etiology and by a poor response to common therapies. The ineffectiveness and the frequent side effects of the drugs used to counteract neuropathic pain call for the discovery of new therapeutic strategies. Laser therapy proved to be effective for reducing pain sensitiv...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-45469-5
更新日期:2019-06-26 00:00:00
abstract::The overlap between pain and reward processing pathways leds researchers to hypothesize that there are interactions between them in the human brain. Two hypotheses have been proposed. The "competition hypothesis" posits that reward can reduce pain-related neural activity and vice versa. The "salience hypothesis" sugge...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep26426
更新日期:2016-05-19 00:00:00
abstract::Alignment-free methods, in which shared properties of sub-sequences (e.g. identity or match length) are extracted and used to compute a distance matrix, have recently been explored for phylogenetic inference. However, the scalability and robustness of these methods to key evolutionary processes remain to be investigat...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep06504
更新日期:2014-09-30 00:00:00
abstract::Few-layer black phosphorus (BP) is the most promising material among the two-dimensional materials due to its layered structure and the excellent semiconductor properties. Currently, thin BP atomic layers are obtained mostly by mechanical exfoliation of bulk BP, which limits applications in thin-film based electronics...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep23736
更新日期:2016-03-30 00:00:00
abstract::The current study was conducted to assess the effects of microinjection of different dosages of guide RNA (gRNA)/Cas9 protein on the mutation rate, embryo survival, embryonic development, hatchability and early fry survival in channel catfish, Ictalurus punctatus. Guide RNAs targeting two of the channel catfish immune...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-34738-4
更新日期:2018-11-07 00:00:00
abstract::Telomeres play an important role in maintaining chromosomal integrity. With each cell division, telomeres are shortened and leukocyte telomere length (LTL) has therefore been considered a marker for biological age. LTL is associated with various lifetime stressors and health-related outcomes. Transgenerational effects...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-71000-2
更新日期:2020-08-19 00:00:00
abstract::As the natural boundary between the Yunnan-Guizhou Plateau and the Hengduan Mountains in China, the large-scale prominent terrain of Ailaoshan Mountain leads to obvious regional differences in climate and vegetation. In this article, a comparative analysis is made on both species composition and floristic components o...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-48324-9
更新日期:2019-08-19 00:00:00
abstract::Mutations affecting the transcription factor FOXP2 cause a rare form of severe speech and language disorder. Although it is clear that sufficient FOXP2 expression is crucial for normal brain development, little is known about how this transcription factor is regulated. To investigate post-translational mechanisms for ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep20911
更新日期:2016-02-12 00:00:00
abstract::We aimed to assess the role of computerized tomography attenuation values (Hounsfield unit-HU) for differentiating pyonephrosis from hydronephrosis and for predicting postoperative infectious complications in patients with obstructive uropathy. We analysed data from 122 patients who underwent nephrostomy tube or urete...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-75672-8
更新日期:2020-10-29 00:00:00
abstract::Electronic cigarettes (ECs) are nicotine delivery devices that are proposed as tobacco harm reduction products to smokers. Nicotine delivery from ECs is potentially important in their efficacy as smoking substitutes. Herein, nicotine delivery from using a new-generation EC device (variable-wattage, set at 9 W) was eva...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep11269
更新日期:2015-06-17 00:00:00
abstract::Auditory neuropathy (AN) is a hearing disorder characterized by normal cochlear amplification to sound but poor temporal processing and auditory perception in noisy backgrounds. These deficits likely result from impairments in auditory neural synchrony; such dyssynchrony of the neural responses has been linked to demy...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-06600-6
更新日期:2017-07-25 00:00:00
abstract::An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...
journal_title:Scientific reports
pub_type: 已发布勘误
doi:10.1038/s41598-020-62904-0
更新日期:2020-04-10 00:00:00
abstract::Doubly curved nanofiber-reinforced optically transparent composites with low thermal expansion of 15 ppm/k are prepared by hot pressing vacuum-filtered Pickering emulsions of hydrophobic acrylic resin monomer, hydrophilic chitin nanofibers and water. The coalescence of acrylic monomer droplets in the emulsion is preve...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep16421
更新日期:2015-11-10 00:00:00
abstract::An on-going debate concerning the dietary adaptations of archaic hominins and early Homo has been fuelled by contradictory inferences obtained using different methodologies. This work presents an extensive comparative sample of 30 extant primate species that was assembled to perform a morpho-functional comparison of t...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-63739-5
更新日期:2020-04-22 00:00:00
abstract::Patient-matched transcriptomic studies using tumour samples before and after treatment allow inter-patient heterogeneity to be controlled, but tend not to include an untreated comparison. Here, Illumina BeadArray technology was used to measure dynamic changes in gene expression from thirty-seven paired diagnostic core...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep29434
更新日期:2016-07-07 00:00:00
abstract::Oxalate decarboxylase (OXDC) enzyme has immense biotechnological applications due to its ability to decompose anti-nutrient oxalic acid. Flammulina velutipes, an edible wood rotting fungus responds to oxalic acid by induction of OXDC to maintain steady levels of pH and oxalate anions outside the fungal hyphae. Here, w...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep14578
更新日期:2015-10-12 00:00:00
abstract::Novel-morphological Fe3O4 nanosheets with magnetochromatic property have been prepared by a modified solvothermal method. Such nanosheets could form one-dimension photonic crystal under an external magnetic field. The Fe3O4 nanosheets suspension could strongly diffract visible light and display varied colors with chan...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep09320
更新日期:2015-03-23 00:00:00
abstract::The global problem of unowned domestic cats, driven by their phenomenal reproductive success, carries significant economic, animal welfare and biodiversity costs. Desexing owned cats prior to puberty prevents unwanted litters that contribute to unowned cat populations. The prevalence and predictors of desexing, and th...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-79513-6
更新日期:2021-01-18 00:00:00
abstract::The aim of the study was to investigate the role of endogenous sulfur dioxide (SO2)/ aspartate aminotransferase 1 (AAT1) pathway in stretch-induced excessive collagen expression and its mechanism. The mechanical stretch downregulated SO2/AAT1 pathway and increased collagen I and III protein expression. Importantly, AA...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep21112
更新日期:2016-02-16 00:00:00
abstract::Brain µ-opioid receptors (MOR) mediate reward and help coping with pain, social rejection, anxiety and depression. The dorsal midline thalamus (dMT) integrates visceral/emotional signals and biases behavior towards aversive or defensive states through projections to the amygdala. While a dense MOR expression in the dM...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-54128-8
更新日期:2019-11-28 00:00:00
abstract::The effects of biodiversity on ecosystem functions have been extensively studied, but little is known about the effects of ecosystem functions on biodiversity. This knowledge is important for understanding biodiversity-ecosystem functioning relationships. Desertification reversal is a significant global challenge, but...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-25875-x
更新日期:2018-05-15 00:00:00
abstract::A scheme is presented to realize a single-photon transistor based on cavity quantum electrodynamics (QED) with Rydberg atomic ensemble. By combining the advantages of the cavity-enhanced interaction and Rydberg blockade, we achieve a high gain single-photon transistor. The numerical calculation shows that by using one...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-41185-2
更新日期:2019-03-18 00:00:00