Detection of genomic regions associated with tiller number in Iranian bread wheat under different water regimes using genome-wide association study.

abstract：:Porphyra 334 (P334), a mycosporine-like amino acid (MAA), is a secondary metabolite found in diverse marine and terrestrial organisms and has several beneficial effects on fibroblast proliferation, wound healing, and antioxidant activity. Here, we report that P334 accelerates the cell reprogramming process of mouse ta...

journal_title：Scientific reports

authors： Yoo J,Kim J,Lee JH,Kim H,Jang SJ,Seo HH,Oh ST,Hyeon SJ,Ryu H,Kim J,Moh SH

更新日期：2020-02-28 00:00:00

abstract：:Invasive giant knotweed (Fallopia sachalinensis) is native to northeastern Asia. In Korea, F. sachalinensis is confined to two volcanic islands, Ullung and Dok islands, where it occurs as dodecaploids (2n = 132). We investigated the molecular variation in 104 accessions from 94 populations of F. sachalinensis and its ...

journal_title：Scientific reports

authors： Park CW,Bhandari GS,Won H,Park JH,Park DS

更新日期：2018-10-30 00:00:00

abstract：:This study aimed to identify and distinguish various factors that may influence the occurrence of mandibular coronoid fractures. From January 2000 to December 2009, a total of 1131 patients with maxillofacial fractures were enrolled in this statistical study to evaluate the association between mandibular coronoid frac...

journal_title：Scientific reports

authors： Zhou HH,Lv K,Yang RT,Li Z,Li ZB

更新日期：2017-05-19 00:00:00

abstract：:Human populations worldwide are increasingly confronted with infectious diseases and antimicrobial resistance spreading faster and appearing more frequently. Knowledge regarding their occurrence and worldwide transmission is important to control outbreaks and prevent epidemics. Here, we performed shotgun sequencing of...

journal_title：Scientific reports

authors： Nordahl Petersen T,Rasmussen S,Hasman H,Carøe C,Bælum J,Schultz AC,Bergmark L,Svendsen CA,Lund O,Sicheritz-Pontén T,Aarestrup FM

更新日期：2015-07-10 00:00:00

abstract：:The eruptive activity of basaltic hotspot volcanoes displays major fluctuations on times scales of years to decades. Theses fluctuations are thought to reflect changes in the rate of mantle melt supply. However, the crustal filter generally masks the mantle processes involved. Here, we show that the cyclic and general...

journal_title：Scientific reports

authors： Vlastélic I,Di Muro A,Bachèlery P,Gurioli L,Auclair D,Gannoun A

更新日期：2018-09-27 00:00:00

abstract：:Functional diversity is thought to enhance ecosystem resilience, driving research focused on trends in the functional composition of fisheries, most recently with new reconstructions of global catch data. However, there is currently little understanding of how accounting for unreported catches (e.g. small-scale and il...

journal_title：Scientific reports

authors： Nash KL,Watson RA,Halpern BS,Fulton EA,Blanchard JL

更新日期：2017-09-06 00:00:00

abstract：:Obesity causes low-grade inflammation that is involved in male infertility. Interleukin 1 beta (IL1β) plays an important role in this process. A high-fat diet (HFD) is the most common cause of obesity. However, the effect of a HFD on IL1β and its consequence in reproduction remain unclear. We established a HFD model i...

journal_title：Scientific reports

authors： Zhang J,Li K,Yuan M,Zhang J,Huang G,Ao J,Tan H,Li Y,Gong D,Li J,Kang L,An N,Li F,Lin P,Huang L

更新日期：2017-04-03 00:00:00

abstract：:Monoclonal antibodies have a variety of applications in research and medicine. Here, we report development of a new method for production of monoclonal antibodies. Our method relies on in vivo RNA transfection rather than peptide vaccination. We took advantage of RNA transcripts complexed with DOTMA and DOPE lipids to...

journal_title：Scientific reports

authors： Romani B,Kavyanifard A,Allahbakhshi E

更新日期：2017-09-07 00:00:00

abstract：:Förster Resonance Energy Transfer (FRET) allows for the visualization of nanometer-scale distances and distance changes. This sensitivity is regularly achieved in single-molecule experiments in vitro but is still challenging in biological materials. Despite many efforts, quantitative FRET in living samples is either r...

journal_title：Scientific reports

authors： Coullomb A,Bidan CM,Qian C,Wehnekamp F,Oddou C,Albigès-Rizo C,Lamb DC,Dupont A

更新日期：2020-04-16 00:00:00

abstract：:The niacin receptor HCA2 is implicated in controlling inflammatory host responses with yet poorly understood mechanistic basis. We previously reported that HCA2 in A431 epithelial cells transduced Gβγ-protein kinase C- and Gβγ-metalloproteinase/EGFR-dependent MAPK/ERK signaling cascades. Here, we investigated the role...

journal_title：Scientific reports

authors： Shi Y,Lai X,Ye L,Chen K,Cao Z,Gong W,Jin L,Wang C,Liu M,Liao Y,Wang JM,Zhou N

更新日期：2017-02-10 00:00:00

abstract：:To tailor the properties of colloidal materials, precise control over the self-assembly of their constituents is a prerequisite. Here, we govern the assembly of silica particles by functionalization with supramolecular moieties which interact with each other via directional and reversible hydrogen bonding. Through a g...

journal_title：Scientific reports

authors： Vilanova N,Feijter I,Teunissen AJP,Voets IK

更新日期：2018-01-19 00:00:00

abstract：:The development of novel small molecule inhibitors of the cancer-associated tropomyosin 3.1 (Tpm3.1) provides the ability to examine the metabolic function of specific actin filament populations. We have determined the ability of these anti-Tpm (ATM) compounds to regulate glucose metabolism in mice. Acute treatment (1...

journal_title：Scientific reports

authors： Kee AJ,Chagan J,Chan JY,Bryce NS,Lucas CA,Zeng J,Hook J,Treutlein H,Laybutt DR,Stehn JR,Gunning PW,Hardeman EC

更新日期：2018-03-15 00:00:00

abstract：:Polypoidal choroidal vasculopathy (PCV) is a distinctive type of neovascular age-related macular degeneration prevalent in many Asian countries. However, there is still some controversy in how the subtypes of PCV are classified. This post-hoc study redefined the branching vascular network (BVN) and PCV subtypes throug...

journal_title：Scientific reports

authors： Yeung L,Lai CC,Chen SN,Cheng CK,Yang CM,Hsieh YT,Tsai A,Yang CH

更新日期：2021-01-11 00:00:00

abstract：:Effective quality assurance is essential in any screening programme. This article provides a unique insight into key quality indicators of five rounds of the first population-based colorectal cancer screening programme implemented in Spain (2000-2012), providing the results according to the type of screening (prevalen...

journal_title：Scientific reports

authors： Binefa G,Garcia M,Milà N,Fernández E,Rodríguez-Moranta F,Gonzalo N,Benito L,Clopés A,Guardiola J,Moreno V

更新日期：2016-01-20 00:00:00

abstract：:Diabetes is an independent risk factor for development of heart failure and has been associated with poor outcomes in these patients. The prevalence of diabetes continues to rise. Using routine HbA1c measurements on inpatients at a tertiary hospital, we aimed to investigate the prevalence of diabetes amongst patients ...

journal_title：Scientific reports

authors： Khoo K,Lew J,Neef P,Kearney L,Churilov L,Robbins R,Tan A,Hachem M,Owen-Jones L,Lam Q,Hart GK,Wilson A,Sumithran P,Johnson D,Srivastava PM,Farouque O,Burrell LM,Zajac JD,Ekinci EI

更新日期：2018-09-10 00:00:00

abstract：:The medicinal leech has established a long-term mutualistic association with Aeromonas veronii, a versatile bacterium which can also display free-living waterborne and fish- or human-pathogenic lifestyles. Here, we investigated the role of antibiotics in the dynamics of interaction between the leech and its gut symbio...

journal_title：Scientific reports

authors： Tasiemski A,Massol F,Cuvillier-Hot V,Boidin-Wichlacz C,Roger E,Rodet F,Fournier I,Thomas F,Salzet M

更新日期：2015-12-04 00:00:00

abstract：:We developed a reporter system that can be used in a dual manner in visualizing mature osteoblast formation. The system is based on a helper-dependent adenoviral vector (HDAdV), in which a fluorescent protein, Venus, is expressed under the control of the 19-kb human osteocalcin (OC) genomic locus. By infecting human a...

journal_title：Scientific reports

authors： Sone T,Shin M,Ouchi T,Sasanuma H,Miyamoto A,Ohte S,Tsukamoto S,Nakanishi M,Okano H,Katagiri T,Mitani K

更新日期：2019-07-04 00:00:00

abstract：:Deregulated IGF-1R-AKT signaling influences multiple nodes of cancer cell physiology and assists in migration, metastasis and acquirement of radio/chemoresistance. Enrichment of cancer stem cells (CSC) positively correlates with radio/chemoresistance development in various malignancies. It is unclear though, how IGF-1...

journal_title：Scientific reports

authors： Singh RK,Dhadve A,Sakpal A,De A,Ray P

更新日期：2016-11-07 00:00:00

abstract：:Antimicrobial peptides (AMPs) represent a promising class of novel antimicrobial agents owing to their potent antimicrobial activity. In this study, two lead peptides from unrelated classes of AMPs were systematically hybridized into a series of five hybrid peptides (DM1-DM5) with conserved N- and C-termini. This appr...

journal_title：Scientific reports

authors： Le CF,Yusof MY,Hassan H,Sekaran SD

更新日期：2015-05-18 00:00:00

abstract：:The mechanism by which chronic metabolic acidosis (CMA) regulates sodium (Na(+))-chloride (Cl(-)) cotransporter (NCC) in the renal distal convoluted tubules remains unexplored. We examined the role of STE20/SPS1-related proline/alanine-rich kinase (SPAK) and with-no-lysine kinase 4 (WNK4) on expression of NCC in mouse...

journal_title：Scientific reports

authors： Fang YW,Yang SS,Cheng CJ,Tseng MH,Hsu HM,Lin SH

更新日期：2016-01-05 00:00:00

abstract：:L-arginine:glycine amidinotransferase (AGAT) and its metabolites creatine and homoarginine (HA) have been linked to cardiovascular pathologies in both human and murine studies, but the underlying molecular mechanisms are poorly understood. Here, we report the first analysis of heart transcriptome variation using micro...

journal_title：Scientific reports

authors： Jensen M,Müller C,Choe CU,Schwedhelm E,Zeller T

更新日期：2020-03-16 00:00:00

abstract：:The success of mesenchymal stem cell transplantation is highly dependent on their survival and controlled fate regulation. This study demonstrates that dual-delivery of connective tissue growth factor (CTGF) and fibroblast growth factor 2 (FGF-2) from a core-shell fiber of Silk Fibroin/poly(L-lactic acid-co-ε-caprolac...

journal_title：Scientific reports

authors： Xu R,Zhao H,Muhammad H,Dong M,Besenbacher F,Chen M

更新日期：2017-08-17 00:00:00

abstract：:Osteoporosis is associated with reduced density and quality of bone leading to weakened skeleton thereby increasing the risk of fractures responsible for increased morbidity and mortality. Due to preference for western food style the consumption of salt intake in our diets has increased many folds. High dietary salt i...

journal_title：Scientific reports

authors： Dar HY,Singh A,Shukla P,Anupam R,Mondal RK,Mishra PK,Srivastava RK

更新日期：2018-02-06 00:00:00

abstract：:We utilized several computational approaches to evaluate the binding energies of tyrosine (Tyr) and several unnatural Tyr analogs, to several orthogonal aaRSes derived from Methanocaldococcus jannaschii and Escherichia coli tyrosyl-tRNA synthetases. The present study reveals the following: (1) AutoDock Vina and ROSETT...

journal_title：Scientific reports

authors： Ren W,Truong TM,Ai HW

更新日期：2015-07-29 00:00:00

abstract：:There is significant interest in understanding the pathophysiology of Obsessive-Compulsive Disorder (OCD) using resting-state fMRI (rsfMRI). Previous studies acknowledge abnormalities within and beyond the fronto-striato-limbic circuit in OCD that require further clarifications. However, limited information could be i...

journal_title：Scientific reports

authors： Kashyap R,Eng GK,Bhattacharjee S,Gupta B,Ho R,Ho CSH,Zhang M,Mahendran R,Sim K,Chen SHA

更新日期：2021-01-14 00:00:00

abstract：:Axonal injury is a common feature of central nervous system insults that culminates with the death of the affected neurons, and an irreversible loss of function. Inflammation is an important component of the neurodegenerative process, where the microglia plays an important role by releasing proinflammatory factors as ...

journal_title：Scientific reports

authors： Nadal-Nicolás FM,Galindo-Romero C,Valiente-Soriano FJ,Barberà-Cremades M,deTorre-Minguela C,Salinas-Navarro M,Pelegrín P,Agudo-Barriuso M

更新日期：2016-12-08 00:00:00

abstract：:The use of micro- and nanodevices as multifunctional systems for biomedical applications has experienced an exponential growth during the past decades. Although a large number of studies have focused on the design and fabrication of new micro- and nanosystems capable of developing multiple functions, a deeper understa...

journal_title：Scientific reports

authors： Patiño T,Soriano J,Barrios L,Ibáñez E,Nogués C

更新日期：2015-06-12 00:00:00

abstract：:Listeria monocytogenes is well known for having the ability to cross the placental barrier, leading to fetal infections and abortion. However, the mechanisms leading to infectious abortion are poorly understood. In this study, we demonstrate that interferon γ-induced GTPase (IGTP) contributes to the invasion of L. mon...

journal_title：Scientific reports

authors： Tachibana M,Hashino M,Watanabe K,Shimizu T,Watarai M

更新日期：2015-02-03 00:00:00

abstract：:Curcumin is an important bioactive component of turmeric and also one of the important natural products, which has been investigated extensively. The precise mode of action of curcumin and its impact on system level protein networks are still not well studied. To identify the curcumin governed regulatory action on pro...

journal_title：Scientific reports

authors： Dhasmana A,Uniyal S,Anukriti,Kashyap VK,Somvanshi P,Gupta M,Bhardwaj U,Jaggi M,Yallapu MM,Haque S,Chauhan SC

更新日期：2020-07-21 00:00:00

abstract：:Melanoma is the most lethal cutaneous cancer. New drugs have recently appeared; however, not all patients obtain a benefit of these new drugs. For this reason, it is still necessary to characterize melanoma at molecular level. The aim of this study was to explore the molecular differences between melanoma tumor subtyp...

journal_title：Scientific reports

authors： Trilla-Fuertes L,Gámez-Pozo A,Prado-Vázquez G,Zapater-Moros A,Díaz-Almirón M,Fortes C,Ferrer-Gómez M,López-Vacas R,Parra Blanco V,Márquez-Rodas I,Soria A,Fresno Vara JÁ,Espinosa E

更新日期：2019-05-10 00:00:00