Physical Activity, Energy Expenditure, and Defense of Body Weight in Melanocortin 4 Receptor-Deficient Male Rats.

abstract：:The absorption spectra in array of Ge, Al and Ge/Al-shell nanoparticles immersed in alumina (Al2O3) matrix is calculated in framework of ab initio macroscopic dielectric model. It is demonstrated that absorption is strongly enhanced when germanium nanospheres are encapsulated by Al-shell. Two absorption peaks, appeari...

journal_title：Scientific reports

authors： Despoja V,Basioli L,Parramon JS,Mičetić M

更新日期：2020-01-09 00:00:00

abstract：:An impairment of cardiac function is a key feature of the cardiovascular failure associated with sepsis. Although there is some evidence that suppression of sarcoplasmic reticulum Ca2+-ATP-ase (SERCA2) contributes to septic cardiomyopathy, it is not known whether prevention of the down-regulation of SERCA2 improves ou...

journal_title：Scientific reports

authors： Martin L,Horst K,Chiazza F,Oggero S,Collino M,Brandenburg K,Hildebrand F,Marx G,Thiemermann C,Schuerholz T

更新日期：2016-11-17 00:00:00

abstract：:Higher plants have been shown to experience a juvenile vegetative phase, an adult vegetative phase, and a reproductive phase during its postembryonic development and distinct lateral organ morphologies have been observed at the different development stages. Populus euphratica, commonly known as a desert poplar, has de...

journal_title：Scientific reports

authors： Ma X,Ma J,Fan D,Li C,Jiang Y,Luo K

更新日期：2016-09-08 00:00:00

abstract：:Nitrogen (N) is a major component of the photosynthetic apparatus and is widely used as a fertilizer in crops. However, to the best of our knowledge, the dynamic of photosynthesis establishment due to differential N supply in the bioenergy crop sugarcane has not been reported to date. To address this question, we eval...

journal_title：Scientific reports

authors： Bassi D,Menossi M,Mattiello L

更新日期：2018-02-02 00:00:00

abstract：:In this study, a model assisted strategy is developed to control the distribution of colloids in porous media in the framework of nanoremediation, an innovative environmental nanotechnology aimed at reclaiming contaminated aquifers. This approach is exemplified by the delivery of humic acid-stabilized iron oxide nanop...

journal_title：Scientific reports

authors： Bianco C,Patiño Higuita JE,Tosco T,Tiraferri A,Sethi R

更新日期：2017-10-11 00:00:00

abstract：:Thymocyte and T cell trafficking relies on signals initiated by G-protein coupled receptors. To address the importance of the G-proteins Gαi2 and Gαi3 in thymocyte and T cell function, we developed several mouse models. Gαi2 deficiency in hematopoietic progenitors led to a small thymus, a double negative (DN)1/DN2 thy...

journal_title：Scientific reports

authors： Hwang IY,Harrison K,Park C,Kehrl JH

更新日期：2017-06-23 00:00:00

abstract：:A major challenge in current exome sequencing in autosomal recessive (AR) families is the lack of an effective method to prioritize single-nucleotide variants (SNVs). AR families are generally too small for linkage analysis, and length of homozygous regions is unreliable for identification of causative variants. Vario...

journal_title：Scientific reports

authors： Imai A,Nakaya A,Fahiminiya S,Tétreault M,Majewski J,Sakata Y,Takashima S,Lathrop M,Ott J

更新日期：2015-07-06 00:00:00

abstract：:Ultraviolet (UV) B radiation is a dangerous environmental stressor, which can lead to photoaging, inflammation, immune suppression and tumour formation. A recent report has shown the transcriptional activation of several skin-specific genes including matrix metalloproteases (MMPs) in response to UV irradiation. Here, ...

journal_title：Scientific reports

authors： Ujfaludi Z,Tuzesi A,Majoros H,Rothler B,Pankotai T,Boros IM

更新日期：2018-02-08 00:00:00

abstract：:Most large herbivores in arid landscapes need to drink which constrains their movements and makes them vulnerable to disturbance. Asiatic wild ass or khulan (Equus hemionus) were widespread and abundant throughout the arid landscapes of Central Asia and Mongolia, but have undergone dramatic population declines and ran...

journal_title：Scientific reports

authors： Payne JC,Buuveibaatar B,Bowler DE,Olson KA,Walzer C,Kaczensky P

更新日期：2020-02-19 00:00:00

abstract：:Fibroblast growth factor (FGF) 23 is a phosphaturic hormone that directly targets cardiac myocytes via FGF receptor (FGFR) 4 thereby inducing hypertrophic myocyte growth and the development of left ventricular hypertrophy (LVH) in rodents. Serum FGF23 levels are highly elevated in patients with chronic kidney disease ...

journal_title：Scientific reports

authors： Grabner A,Schramm K,Silswal N,Hendrix M,Yanucil C,Czaya B,Singh S,Wolf M,Hermann S,Stypmann J,Di Marco GS,Brand M,Wacker MJ,Faul C

更新日期：2017-05-16 00:00:00

abstract：:Randomizing the layer thickness of superlattices (SL) can lead to localization of coherent phonons and thereby reduces the lattice thermal conductivity κ l . In this work, we propose strategies that can suppress incoherent phonon transport in the above random multilayer (RML) structure to further reduce κ l . Molecula...

journal_title：Scientific reports

authors： Chakraborty P,Cao L,Wang Y

更新日期：2017-08-15 00:00:00

abstract：:To attach reliably on various inclined rough surfaces, many insects have evolved both claws and adhesive pads on their feet. However, the interaction between these organs still remains unclear. Here we designed an artificial attachment device, which mimics the structure and function of claws and adhesive pads, and tes...

journal_title：Scientific reports

authors： Song Y,Dai Z,Wang Z,Ji A,Gorb SN

更新日期：2016-05-20 00:00:00

abstract：:Transport of mesoscale particles due to driving flow fields or external forces on a periodic surface appears in many areas. Geometrical and physical characteristics of particles affect the velocities of the particles in these periodic landscapes. In this paper, we present a numerical simulation based on solving the La...

journal_title：Scientific reports

authors： Madadi E,Biagooi M,Mohammadjafari F,Nedaaee Oskoee S

更新日期：2020-10-26 00:00:00

abstract：:Light pollution and its consequences on ecosystems are increasing worldwide. Knowledge on the threshold levels of light pollution at which significant ecological impacts emerge and the size of dark refuges to maintain natural nocturnal processes is crucial to mitigate its negative consequences. Seabird fledglings are ...

journal_title：Scientific reports

authors： Rodríguez A,Rodríguez B,Negro JJ

更新日期：2015-06-02 00:00:00

abstract：:The development of new anode materials having high electrochemical performances and interesting reaction mechanisms is highly required to satisfy the need for long-lasting mobile electronic devices and electric vehicles. Here, we report a layer crystalline structured SnP3 and its unique electrochemical behaviors with ...

journal_title：Scientific reports

authors： Park JW,Park CM

更新日期：2016-10-24 00:00:00

abstract：:Reconstructed annual streamflows using tree-ring chronologies provide useful information on moisture availability during the pre-historic period, but they have limitations in estimating high flows due to the upper bound on soil water holding capacity and trees' metabolic growth limits. We propose a hybrid approach tha...

journal_title：Scientific reports

authors： Mukhopadhyay S,Patskoski JM,Sankarasubramanian A

更新日期：2018-03-21 00:00:00

abstract：:Metabolic images from Positron Emission Tomography (PET) are used routinely for diagnosis, follow-up or treatment planning purposes of cancer patients. In this study we aimed at determining if radiomic features extracted from 18F-Fluoro Deoxy Glucose (FDG) PET images could mirror tumor transcriptomics. In this study w...

journal_title：Scientific reports

authors： Tixier F,Cheze-le-Rest C,Schick U,Simon B,Dufour X,Key S,Pradier O,Aubry M,Hatt M,Corcos L,Visvikis D

更新日期：2020-03-27 00:00:00

abstract：:The function of most long noncoding RNAs (lncRNAs) is unknown. However, recent studies reveal important roles of lncRNAs in regulating cancer-related pathways. Human antisense lncRNA-NKX2-1-AS1 partially overlaps the NKX2-1/TTF1 gene within chromosomal region 14q13.3. Amplification of this region and/or differential e...

journal_title：Scientific reports

authors： Kathuria H,Millien G,McNally L,Gower AC,Tagne JB,Cao Y,Ramirez MI

更新日期：2018-09-26 00:00:00

abstract：:The electrowetting lenses has attracted researchers in many fields, such as biology, beam shaping, and drug delivery. Previous research on electrowetting lens has focused on neither expanding the dynamic focal length range nor reducing the wavefront aberration. However, the properties with large numerical aperture and...

journal_title：Scientific reports

authors： Song X,Zhang H,Li D,Jia D,Liu T

更新日期：2020-10-01 00:00:00

abstract：:Aberrant regulation of BCL-2 family members enables evasion of apoptosis and tumor resistance to chemotherapy. BCL-2 and functionally redundant counterpart, MCL-1, are frequently over-expressed in high-risk diffuse large B-cell lymphoma (DLBCL). While clinical inhibition of BCL-2 has been achieved with the BH3 mimetic...

journal_title：Scientific reports

authors： Dey J,Deckwerth TL,Kerwin WS,Casalini JR,Merrell AJ,Grenley MO,Burns C,Ditzler SH,Dixon CP,Beirne E,Gillespie KC,Kleinman EF,Klinghoffer RA

更新日期：2017-12-21 00:00:00

abstract：:Continuous solidification experiments were carried out with Cu-Bi-Sn alloys under the effects of Electric Current Pulses (ECPs). A model describing the microstructure evolution was developed. The formation of the microstructure in the continuously solidified alloys was calculated. The calculations demonstrated that EC...

journal_title：Scientific reports

authors： Hongxiang J,Jie H,Jiuzhou Z

更新日期：2015-07-31 00:00:00

abstract：:Breast cancer susceptibility gene 1 (BRCA1) located at chromosome 17q12-21 is a classic tumor suppressor gene, and has been considered as a significant role in hereditary breast cancers. Moreover, numerous studies demonstrated the methylation status of CpG islands in the promoter regions of BRCA1 gene was aberrant in ...

journal_title：Scientific reports

authors： Zhang L,Long X

更新日期：2015-12-08 00:00:00

abstract：:There is not a clear consensus regarding the optimal treatment of locally advanced pancreatic disease. There is a potential role for neoadjuvant therapy to treat micrometastatic disease with chemotherapy, as well as for the treatment of local disease with radiotherapy. We evaluated the safety and efficacy of induction...

journal_title：Scientific reports

authors： Fiore M,Ramella S,Valeri S,Caputo D,Floreno B,Trecca P,Trodella LE,Trodella L,D'Angelillo RM,Coppola R

更新日期：2017-04-05 00:00:00

abstract：:Accidental introduction through ballast water and biofouling are currently the main factors responsible for spreading non-indigenous species in the marine realm. In the Southwestern Atlantic, two scleractinian corals, Tubastraea coccinea and T. tagusensis, have been introduced by opportunistic colonization in 1980 and...

journal_title：Scientific reports

authors： Capel KCC,Creed J,Kitahara MV,Chen CA,Zilberberg C

更新日期：2019-09-27 00:00:00

abstract：:Crop wild relatives are valuable resources for future genetic improvement. Here, we report the de novo genome assembly of Musa itinerans, a disease-resistant wild banana relative in subtropical China. The assembled genome size was 462.1 Mb, covering 75.2% of the genome (615.2Mb) and containing 32, 456 predicted protei...

journal_title：Scientific reports

authors： Wu W,Yang YL,He WM,Rouard M,Li WM,Xu M,Roux N,Ge XJ

更新日期：2016-08-17 00:00:00

abstract：:Although re-sequencing of gene panels and mRNA expression profiling are now firmly established in clinical laboratories, in-depth proteome analysis has remained a niche technology, better suited for studying model systems rather than challenging materials such as clinical trial samples. To address this limitation, we ...

journal_title：Scientific reports

authors： Hughes CS,McConechy MK,Cochrane DR,Nazeran T,Karnezis AN,Huntsman DG,Morin GB

更新日期：2016-10-07 00:00:00

abstract：:HCV NS3 protein plays a central role in viral polyprotein processing and RNA replication. We demonstrate that the NS3 protease (NS3(pro)) domain alone can specifically bind to HCV-IRES RNA, predominantly in the SLIV region. The cleavage activity of the NS3 protease domain is reduced upon HCV-RNA binding. More importan...

journal_title：Scientific reports

authors： Ray U,Das S

更新日期：2011-01-01 00:00:00

abstract：:We report on the fabrication of spherical Au spheres by pulsed laser treatment using a KrF excimer laser (248 nm, 25 ns) under ambient conditions as a fast and high throughput fabrication technique. The presented experiments were realized using initial Au layers of 100 nm thickness deposited on optically transparent a...

journal_title：Scientific reports

authors： Schmidl G,Jia G,Gawlik A,Kreusch J,Schmidl F,Dellith J,Dathe A,Lin ZH,Huang JS,Plentz J

更新日期：2018-07-26 00:00:00

abstract：:Magnetron sputtering techniques were used to prepare molecularly smooth titanium thin films possessing an average roughness between 0.18 nm and 0.52 nm over 5 μm × 5 μm AFM scanning areas. Films with an average roughness of 0.52 nm or lower were found to restrict the extent of P. aeruginosa cell attachment, with less ...

journal_title：Scientific reports

authors： Ivanova EP,Truong VK,Webb HK,Baulin VA,Wang JY,Mohammodi N,Wang F,Fluke C,Crawford RJ

更新日期：2011-01-01 00:00:00

abstract：:GPS-derived Total Electron Content (TEC) is an integrated quantity; hence it is difficult to relate the detection of ionospheric perturbations in TEC to a precise altitude. As TEC is weighted by the maximum ionospheric density, the corresponding altitude (hmF2) is, generally, assumed as the perturbation detection alti...

journal_title：Scientific reports

authors： Thomas D,Bagiya MS,Sunil PS,Rolland L,Sunil AS,Mikesell TD,Nayak S,Mangalampalli S,Ramesh DS

更新日期：2018-08-14 00:00:00