NKX2-1-AS1 negatively regulates CD274/PD-L1, cell-cell interaction genes, and limits human lung carcinoma cell migration.

abstract：:Metals can transmit light by tunnelling when they possess skin-depth thickness. Tunnelling can be resonantly enhanced if resonators are added to each side of a metal film, such as additional dielectric layers or periodic structures on a metal surface. Here we show that, even with no additional resonators, tunnelling r...

journal_title：Scientific reports

authors： Kang JH,Park QH

更新日期：2013-01-01 00:00:00

abstract：:The immune system is constantly challenged, being required to protect the organism against a wide variety of infectious pathogens and, at the same time, to avoid autoimmune disorders. One of the most important molecules involved in these events is the Major Histocompatibility Complex class I (MHC-I), responsible for b...

journal_title：Scientific reports

authors： Rigo MM,Antunes DA,Vaz de Freitas M,Fabiano de Almeida Mendes M,Meira L,Sinigaglia M,Vieira GF

更新日期：2015-12-17 00:00:00

abstract：:Ubiquinol-cytochrome c reductase hinge protein (UQCRH) is the hinge protein for the multi-subunit complex III of the mitochondrial electron transport chain and is involved in the electron transfer reaction between cytochrome c1 and c. Recent genome-wide transcriptomic and epigenomic profiling of clear cell renal cell ...

journal_title：Scientific reports

authors： Luo Y,Medina Bengtsson L,Wang X,Huang T,Liu G,Murphy S,Wang C,Koren J 3rd,Schafer Z,Lu X

更新日期：2020-09-14 00:00:00

abstract：:Hurricane Patricia in 2015 was the strongest Pacific hurricane to make landfall in Mexico. Although Patricia fortuitously spared major cities, it reminded us of the threat tropical cyclones (TCs) pose in the eastern North Pacific (ENP) and the importance of improving our understanding and prediction of ENP TCs. Patric...

journal_title：Scientific reports

authors： Fu D,Chang P,Patricola CM

更新日期：2017-05-10 00:00:00

abstract：:Malaria is among the major threats to global health with the main burden of disease being in rural areas of developing countries where accurate diagnosis based on non-invasive samples is in high demand. We here present a novel molecular assay for detection of malaria parasites based on technology that may be adapted f...

journal_title：Scientific reports

authors： Hede MS,Fjelstrup S,Lötsch F,Zoleko RM,Klicpera A,Groger M,Mischlinger J,Endame L,Veletzky L,Neher R,Simonsen AKW,Petersen E,Mombo-Ngoma G,Stougaard M,Ho YP,Labouriau R,Ramharter M,Knudsen BR

更新日期：2018-03-07 00:00:00

abstract：:Si and Ge nanocrystals in oxides are of a large interest for photo-effect applications due to the fine-tuning of the optical bandgap by quantum confinement in nanocrystals. In this work, dense Ge nanocrystals suitable for enhanced photoconduction were fabricated from 60% Ge in TiO2 amorphous layers by low temperature ...

journal_title：Scientific reports

authors： Lepadatu AM,Slav A,Palade C,Dascalescu I,Enculescu M,Iftimie S,Lazanu S,Teodorescu VS,Ciurea ML,Stoica T

更新日期：2018-03-20 00:00:00

abstract：:We studied mechanisms of recombination in InGaN quantum wells in polar and semipolar structures. Photoluminescence measurements show that the optical emission linewidths for polar and semipolar structures are almost identical suggesting the same level of indium fluctuations in quanutm wells. Their "peak-energy-versus-...

journal_title：Scientific reports

authors： Marona L,Schiavon D,Baranowski M,Kudrawiec R,Gorczyca I,Kafar A,Perlin P

更新日期：2020-01-27 00:00:00

abstract：:An orb web's prey capture thread relies on its glue droplets to retain insects until a spider can subdue them. Each droplet's viscoelastic glycoprotein adhesive core extends to dissipate the forces of prey struggle as it transfers force to stiffer, support line flagelliform fibers. In large orb webs, switchback captur...

journal_title：Scientific reports

authors： Opell BD,Stellwagen SD

更新日期：2019-12-30 00:00:00

abstract：:A novel one-pot synthesis of tri-substituted purines and the discovery of purine analogues with trypanocidal activity are reported. The reaction is initiated by a metal-free oxidative coupling of primary alkoxides and diaminopyrimidines with Schiff base formation and subsequent annulation in the presence of large N,N-...

journal_title：Scientific reports

authors： Pineda de las Infantas y Villatoro MJ,Unciti-Broceta JD,Contreras-Montoya R,Garcia-Salcedo JA,Gallo Mezo MA,Unciti-Broceta A,Diaz-Mochon JJ

更新日期：2015-03-16 00:00:00

abstract：:Semisynthetic cephalosporins are widely used antibiotics currently produced by different chemical steps under harsh conditions, which results in a considerable amount of toxic waste. Biocatalytic synthesis by the cephalosporin acylase from Pseudomonas sp. strain N176 is a promising alternative. Despite intensive engin...

journal_title：Scientific reports

authors： Ferrario V,Fischer M,Zhu Y,Pleiss J

更新日期：2019-08-27 00:00:00

abstract：:Learning rules by which cell shape impacts cell function would enable control of cell physiology and fate in medical applications, particularly, on the interface of cells and material of the implants. We defined the phenotypic response of human bone marrow-derived mesenchymal stem cells (hMSCs) to 2176 randomly genera...

journal_title：Scientific reports

authors： Vasilevich AS,Vermeulen S,Kamphuis M,Roumans N,Eroumé S,Hebels DGAJ,van de Peppel J,Reihs R,Beijer NRM,Carlier A,Carpenter AE,Singh S,de Boer J

更新日期：2020-11-04 00:00:00

abstract：:Languages may differ in terms of the functional units of word-form encoding used in spoken word production. It is widely accepted that segments are the primary units used in Indo-European languages. However, it is controversial what the functional units (syllables or segments) in Chinese spoken word production are. In...

journal_title：Scientific reports

authors： Feng C,Yue Y,Zhang Q

更新日期：2019-08-13 00:00:00

abstract：:Cues previously paired with rewarding stimuli induce a time-dependent increase in the motivational craving state (incubation of craving). Whether there is an increase in craving for high-fat (HF) food over time, which may contribute to overeating and obesity, has not been determined. We hypothesized that cues paired w...

journal_title：Scientific reports

authors： Darling RA,Dingess PM,Schlidt KC,Smith EM,Brown TE

更新日期：2016-08-03 00:00:00

abstract：:Ge-monopnictides (GeAs) plays critical role in high-tech industry, especially in the field of advanced optical devices and infrared. As a secondary material, coal fly ash could be further recycled to retrieve germanium and prepare GeAs material with high added values. Hence, the aim of this paper is to propose a one-p...

journal_title：Scientific reports

authors： Zhang L,Xu Z

更新日期：2017-06-16 00:00:00

abstract：:Protein ubiquitylation participates in a number of essential cellular processes including signal transduction and transcription, often by initiating the degradation of specific substrates through the 26S proteasome. Within the ubiquitin-proteasome system, deubiquitylating enzymes (DUBs) not only help generate and main...

journal_title：Scientific reports

authors： Hayama R,Yang P,Valverde F,Mizoguchi T,Furutani-Hayama I,Vierstra RD,Coupland G

更新日期：2019-11-19 00:00:00

abstract：:Flavonoids, due to their pharmacological attributes, have recently become target molecules for metabolic engineering in commonly consumed food crops. Strategies including expression of single genes and gene pyramiding have provided only limited success, due principally to the highly branched and complex biosynthetic p...

journal_title：Scientific reports

authors： Pandey A,Misra P,Bhambhani S,Bhatia C,Trivedi PK

更新日期：2014-05-21 00:00:00

abstract：:While TLR-activated pathways are key regulators of B cell responses in mammals, their impact on teleost B cells are scarcely addressed. Here, the potential of Atlantic salmon B cells to respond to TLR ligands was shown by demonstrating a constitutive expression of nucleic-acid sensing TLRs in magnetic sorted IgM+ cell...

journal_title：Scientific reports

authors： Jenberie S,Thim HL,Sunyer JO,Skjødt K,Jensen I,Jørgensen JB

更新日期：2018-02-23 00:00:00

abstract：:In this observational study we investigated whether levels of factor XIII (FXIII) and its major polymorphisms affect the outcome of thrombolysis by recombinant tissue plasminogen activator (rtPA) in acute ischemic stroke (AIS) patients. Study cohort included 132 consecutive AIS patients undergoing i.v. thrombolysis wi...

journal_title：Scientific reports

authors： Székely EG,Czuriga-Kovács KR,Bereczky Z,Katona É,Mezei ZA,Nagy A,Tóth NK,Berényi E,Muszbek L,Csiba L,Bagoly Z

更新日期：2018-05-16 00:00:00

abstract：:A new ether-based electrolyte to match lithium metal electrode is prepared by introducing 1, 4-dioxane as co-solvent into lithium bis(fluorosulfonyl)imide/1,2-dimethoxyethane solution. Under the synergetic effect of solvents and salt, this simple liquid electrolyte presents stable Li cycling with dendrite-free Li depo...

journal_title：Scientific reports

authors： Miao R,Yang J,Xu Z,Wang J,Nuli Y,Sun L

更新日期：2016-02-16 00:00:00

abstract：:The risk of suffering from Alzheimer's disease (AD) is higher in individuals from AD-affected mothers. The purpose of this investigation was to study whether maternal transmission might produce AD-related alterations in progenies of mice that do not have any genotypic alteration. We used cognitively-intact mothers har...

journal_title：Scientific reports

authors： Zamarbide M,Gil-Bea FJ,Bannenberg P,Martínez-Pinilla E,Sandoval J,Franco R,Pérez-Mediavilla A

更新日期：2018-04-24 00:00:00

abstract：:Application of acute kidney injury (AKI) biomarkers with consideration of nonrenal conditions and systemic severity has not been sufficiently determined. Herein, urinary neutrophil gelatinase-associated lipocalin (NGAL), L-type fatty acid-binding protein (L-FABP) and nonrenal disorders, including inflammation, hypoper...

journal_title：Scientific reports

authors： Asada T,Isshiki R,Hayase N,Sumida M,Inokuchi R,Noiri E,Nangaku M,Yahagi N,Doi K

更新日期：2016-09-08 00:00:00

abstract：:A connection between airway and gut microbiota related to allergen exposure in childhood allergies was not well addressed. We aimed to identify the microbiota alterations in the airway and gut related to mite-specific IgE responses in young children with airway allergies. This study enrolled 60 children, including 38 ...

journal_title：Scientific reports

authors： Chiu CY,Chan YL,Tsai MH,Wang CJ,Chiang MH,Chiu CC,Su SC

更新日期：2020-08-10 00:00:00

abstract：:Transcriptome analysis by RNA-seq technology allows novel insights into gene expression and regulatory networks in health and disease. To better understand the molecular basis of renal fibrosis, we performed RNA-seq analysis in the Unilateral Ureteric Obstruction (UUO) mouse model. We analysed sham operated, 2- and 8-...

journal_title：Scientific reports

authors： Arvaniti E,Moulos P,Vakrakou A,Chatziantoniou C,Chadjichristos C,Kavvadas P,Charonis A,Politis PK

更新日期：2016-05-18 00:00:00

abstract：:Acquired cholesteatoma is a chronic inflammatory disease characterized by both hyperkeratinized squamous epithelial overgrowth and bone destruction. Toll-like receptor (TLR) activation and subsequent inflammatory cytokine production are closely associated with inflammatory bone disease. However, the expression and fun...

journal_title：Scientific reports

authors： Si Y,Chen YB,Chen SJ,Zheng YQ,Liu X,Liu Y,Jiang HL,Xu G,Li ZH,Huang QH,Xiong H,Zhang ZG

更新日期：2015-12-07 00:00:00

abstract：:Ensuring lumpfish health and welfare in salmon farms is vital to reduce the high mortality rates reported and to guarantee a high delousing efficiency. Recent observations of farmed lumpfish livers have shown colours ranging from pale (colours 1 and 2), through bright orange (colours 3 and 4), to dark reddish-brown (c...

journal_title：Scientific reports

authors： Eliasen K,Patursson EJ,McAdam BJ,Pino E,Morro B,Betancor M,Baily J,Rey S

更新日期：2020-06-02 00:00:00

abstract：:Time dependent plastic deformation in a single crystal nickel-base superalloy during cooling from casting relevant temperatures has been studied using a combination of in-situ neutron diffraction, transmission electron microscopy and modelling. Visco-plastic deformation during cooling was found to be dependent on the ...

journal_title：Scientific reports

authors： Panwisawas C,D'Souza N,Collins DM,Bhowmik A

更新日期：2017-09-11 00:00:00

abstract：:Aconiti Lateralis Radix Praeparata (Fuzi) and Fritillariae Thunbergii bulbus (Beimu) have been widely used clinically to treat cardiopulmonary related diseases in China. However, according to the classic rules of traditional Chinese medicine, Fuzi and Beimu should be prohibited to use as a combination for their incomp...

journal_title：Scientific reports

authors： Zhuang P,Huang Y,Lu Z,Yang Z,Xu L,Sun F,Zhang Y,Duan J

更新日期：2016-10-14 00:00:00

abstract：:Fertilisation datasets collected from field experiments (n = 21) in tea-producing areas from 2016 to 2018 were used to build a quantitative evaluation of the fertility of tropical soils (QUEFTS) model to estimate nutrient uptake of tea plants, and to investigate relationships between tea yield and nutrient accumulatio...

journal_title：Scientific reports

authors： Tang S,Liu Y,Zheng N,Li Y,Ma Q,Xiao H,Zhou X,Xu X,Jiang T,He P,Wu L

更新日期：2020-02-04 00:00:00

abstract：:Fatal Familial Insomnia (FFI) is a genetic prion disease caused by a point mutation in the prion protein gene (PRNP) characterized by prominent thalamic atrophy, diffuse astrogliosis and moderate deposition of PrPSc in the brain. Here, for the first time, we demonstrate that the olfactory mucosa (OM) of patients with ...

journal_title：Scientific reports

authors： Redaelli V,Bistaffa E,Zanusso G,Salzano G,Sacchetto L,Rossi M,De Luca CM,Di Bari M,Portaleone SM,Agrimi U,Legname G,Roiter I,Forloni G,Tagliavini F,Moda F

更新日期：2017-04-07 00:00:00

abstract：:The anhydrofructose pathway is an alternate pathway for glycogen degradation by α-1,4-glucan lyase. The sugar 1,5-anhydro-D-fructose (1,5-AF) acts as the central intermediate of this pathway, but its physiological role of in mammals is unclear. Glycation reactions forming advanced glycation end-products (AGEs) are imp...

journal_title：Scientific reports

authors： Sakasai-Sakai A,Takata T,Suzuki H,Maruyama I,Motomiya Y,Takeuchi M

更新日期：2019-07-15 00:00:00