NKX2-1-AS1 negatively regulates CD274/PD-L1, cell-cell interaction genes, and limits human lung carcinoma cell migration.

abstract：:Plant litter is an important component in wetland ecosystems, and the role of plant litter decomposition is considered to be important for wetland ecosystem functions and services. However, the consequences of litter inputs have seldom been experimentally tested in real ecosystems such as constructed wetlands (CWs). T...

journal_title：Scientific reports

authors： Ping Y,Pan X,Li W,Wang J,Cui L

更新日期：2019-09-25 00:00:00

abstract：:Whole-room indirect calorimeters (WRICs) have traditionally been used for real-time resting metabolic rate (RMR) measurements, while metabolic rate (MR) during short-interval exercises has commonly been measured by metabolic carts (MCs). This study aims to investigate the feasibility of incorporating short-interval ex...

journal_title：Scientific reports

authors： Chen S,Scott C,Pearce JV,Farrar JS,Evans RK,Celi FS

更新日期：2020-08-31 00:00:00

abstract：:Improving feed efficiency (FE) is a major goal of pig breeding, reducing production costs and providing sustainability to the pig industry. Reliable predictors for FE could assist pig producers. We carried out untargeted blood metabolite profiling in uncastrated males from Danbred Duroc (n = 59) and Danbred Landrace (...

journal_title：Scientific reports

authors： Carmelo VAO,Banerjee P,da Silva Diniz WJ,Kadarmideen HN

更新日期：2020-01-14 00:00:00

abstract：:Anammox is a cost-effective process to treat nitrogenous wastewater. In this work, excitation-emission matrix (EEM) fluorescence spectroscopy was used to characterize the intracellular and extracellular substances of anammox sludge during reactor operation of 276 days. Four main fluorophores were identified from the i...

journal_title：Scientific reports

authors： Hou X,Liu S,Feng Y

更新日期：2017-01-16 00:00:00

abstract：:Pigeons learned to discriminate two different patterns displayed with miniature light-emitting diode arrays. They were then tested with 84 interspersed, non-reinforced degraded pattern pairs. Choices ranged between 100% and 50% for one or other of the patterns. Stimuli consisting of few pixels yielded low choice score...

journal_title：Scientific reports

authors： Delius JD,Delius JAM

更新日期：2019-09-26 00:00:00

abstract：:Bed bugs are pests of public health importance due to their relentless biting habits that can lead to allergies, secondary infections and mental health issues. When not feeding on human blood bed bugs aggregate in refuges close to human hosts. This aggregation behaviour could be exploited to lure bed bugs into traps f...

journal_title：Scientific reports

authors： Weeks ENI,Logan JG,Birkett MA,Caulfield JC,Gezan SA,Welham SJ,Brugman VA,Pickett JA,Cameron MM

更新日期：2020-03-12 00:00:00

abstract：:The wheat avenin-like proteins (ALP) are considered atypical gluten constituents and have shown positive effects on dough properties revealed using a transgenic approach. However, to date the genetic architecture of ALP genes is unclear, making it impossible to be utilized in wheat breeding. In the current study, thre...

journal_title：Scientific reports

authors： Chen XY,Cao XY,Zhang YJ,Islam S,Zhang JJ,Yang RC,Liu JJ,Li GY,Appels R,Keeble-Gagnere G,Ji WQ,He ZH,Ma WJ

更新日期：2016-08-09 00:00:00

abstract：:Many experiments on human cooperation have revealed that individuals differ systematically in their tendency to cooperate with others. It has also been shown that individuals condition their behaviour on the overall cooperation level of their peers. Yet, little is known about how individuals respond to heterogeneity i...

journal_title：Scientific reports

authors： van den Berg P,Molleman L,Junikka J,Puurtinen M,Weissing FJ

更新日期：2015-11-04 00:00:00

abstract：:Rapid eye movement (REM) sleep is considered to preferentially reprocess emotionally arousing memories. We tested this hypothesis by cueing emotional vs. neutral memories during REM and NREM sleep and wakefulness by presenting associated verbal memory cues after learning. Here we show that cueing during NREM sleep sig...

journal_title：Scientific reports

authors： Lehmann M,Schreiner T,Seifritz E,Rasch B

更新日期：2016-12-16 00:00:00

abstract：:Quantification of cellular antigens and their interactions via antibody-based detection methods are widely used in scientific research. Accurate high-throughput quantitation of these assays using general image analysis software can be time consuming and challenging, particularly when attempted by users with limited im...

journal_title：Scientific reports

authors： Law AMK,Yin JXM,Castillo L,Young AIJ,Piggin C,Rogers S,Caldon CE,Burgess A,Millar EKA,O'Toole SA,Gallego-Ortega D,Ormandy CJ,Oakes SR

更新日期：2017-11-16 00:00:00

abstract：:In 2010, a new rabbit hemorrhagic disease virus (RHDV) variant, designated RHDV2, was identified for the first time in Italy. Studies have shown that RHDV2 differs from RHDV1 (traditional RHDV) in terms of its antigenic profile and genetic characteristics. The VP60 protein of RHDV is a structural protein that plays im...

journal_title：Scientific reports

authors： Kong D,Liu J,Jiang Q,Yu Z,Hu X,Guo D,Huang Q,Jiao M,Qu L

更新日期：2016-02-16 00:00:00

abstract：:Recently, a computer-generated moiré profilometry was proposed by our research group. It can effectively avoid the influence of the transient caused by moiré fringes' direct acquisition and generally owns a higher accuracy. But when the spatial spectrum of the captured deformed pattern is severely aliased caused by th...

journal_title：Scientific reports

authors： Li C,Cao Y,Wang L,Wan Y,Fu G,Wang Y,Chen C

更新日期：2019-05-24 00:00:00

abstract：:GABA counteracts wide range of stresses through regulation of GABA shunt pathway in plants. Although, GABA assisted tolerance against As toxicity in plants is still unexplored. We have examined GABA induced tolerance in rice seedlings with two exposure periods of GABA i.e., short term and long term. Results showed tha...

journal_title：Scientific reports

authors： Kumar N,Dubey AK,Upadhyay AK,Gautam A,Ranjan R,Srikishna S,Sahu N,Behera SK,Mallick S

更新日期：2017-08-18 00:00:00

abstract：:Cuprizone-induced demyelination in mice is a frequently used model in preclinical multiple sclerosis research. A recent quantitative clinically-targeted MRI method, fast macromolecular proton fraction (MPF) mapping demonstrated a promise as a myelin biomarker in human and animal studies with a particular advantage of ...

journal_title：Scientific reports

authors： Khodanovich MY,Sorokina IV,Glazacheva VY,Akulov AE,Nemirovich-Danchenko NM,Romashchenko AV,Tolstikova TG,Mustafina LR,Yarnykh VL

更新日期：2017-04-24 00:00:00

abstract：:Precise temporal coding is necessary for proper acoustic analysis. However, at cortical level, forward suppression appears to limit the ability of neurons to extract temporal information from natural sound sequences. Here we studied how temporal processing can be maintained in the bats' cortex in the presence of suppr...

journal_title：Scientific reports

authors： Beetz MJ,Hechavarría JC,Kössl M

更新日期：2016-06-30 00:00:00

abstract：:Bezafibrate (BzF) is eliminated by renal excretion and dosage must be reduced in patients with chronic kidney disease (CKD). There is a concern that BzF causes a further deterioration in renal function in patients with CKD. This study assessed whether BzF discontinuation or dose reduction in CKD patients improves rena...

journal_title：Scientific reports

authors： Zingerman B,Ziv D,Feder Krengel N,Korzets A,Matok I

更新日期：2020-11-13 00:00:00

abstract：:Human papillomavirus (HPV)-positive head and neck squamous cell carcinoma (HNSCC) is biologically distinct from HPV-negative HNSCC. Outside of HPV-status, few tumor-intrinsic variables have been identified that correlate to improved survival. As part of exploratory analysis into the trace elemental composition of orop...

journal_title：Scientific reports

authors： Poropatich K,Paunesku T,Zander A,Wray B,Schipma M,Dalal P,Agulnik M,Chen S,Lai B,Antipova O,Maxey E,Brown K,Wanzer MB,Gursel D,Fan H,Rademaker A,Woloschak GE,Mittal BB

更新日期：2019-11-18 00:00:00

abstract：:Microbial secondary metabolites are valuable resources for novel drug discovery. In particular, actinomycetes expressed a range of antibiotics against a spectrum of bacteria. In genus level, strain Allosalinactinospora lopnorensis CA15-2(T) is the first new actinomycete isolated from the Lop Nor region, China. Antimic...

journal_title：Scientific reports

authors： Huang C,Leung RK,Guo M,Tuo L,Guo L,Yew WW,Lou I,Lee SMY,Sun C

更新日期：2016-02-11 00:00:00

abstract：:The use of biopurification systems (BPS) constitutes an efficient strategy to eliminate pesticides from polluted wastewaters from farm activities. BPS environments contain a high microbial density and diversity facilitating the exchange of information among bacteria, mediated by mobile genetic elements (MGEs), which p...

journal_title：Scientific reports

authors： Martini MC,Wibberg D,Lozano M,Torres Tejerizo G,Albicoro FJ,Jaenicke S,van Elsas JD,Petroni A,Garcillán-Barcia MP,de la Cruz F,Schlüter A,Pühler A,Pistorio M,Lagares A,Del Papa MF

更新日期：2016-06-20 00:00:00

abstract：:The mitogen-activated protein kinase (MAPK)-mediated phosphorylation cascade is a vital component of plant cellular signalling. Despite this, MAPK signalling cascade is less characterized in crop legumes. To fill this void, we present here a comprehensive phylogeny of MAPK kinases (MKKs) and MAPKs identified from 16 l...

journal_title：Scientific reports

authors： Purayannur S,Kumar K,Kaladhar VC,Verma PK

更新日期：2017-07-10 00:00:00

abstract：:Hybrid carbon films composed of graphene film and porous carbon film may give full play to the advantages of both carbon materials, and have great potential for application in energy storage and conversion devices. Unfortunately, there are very few reports on fabrication of hybrid carbon films. Here we demonstrate a s...

journal_title：Scientific reports

authors： Wei H,Wei S,Tian W,Zhu D,Liu Y,Yuan L,Li X

更新日期：2014-11-14 00:00:00

abstract：:In the present study, we obtained population genetic data and forensic parameters of 30 InDel loci in Chinese Xibe ethnic group from northwestern China and studied the genetic relationships between the studied Xibe group and other reference groups. The observed heterozygosities ranged from 0.1704 at HLD118 locus to 0....

journal_title：Scientific reports

authors： Meng HT,Zhang YD,Shen CM,Yuan GL,Yang CH,Jin R,Yan JW,Wang HD,Liu WJ,Jing H,Zhu BF

更新日期：2015-02-05 00:00:00

abstract：:Atomistic chemical inhomogeneities are anticipated to induce dissimilarities in surface potentials, which control corrosion initiation of alloys at the atomic scale. Precise understanding of corrosion is therefore hampered by lack of definite information describing how atomistic heterogeneities regulate the process. H...

journal_title：Scientific reports

authors： Zhang B,Wang J,Wu B,Oguzie EE,Luo K,Ma XL

更新日期：2016-12-21 00:00:00

abstract：:In this work, we utilise a combination of theory, computation and experiments to understand the early events related to the nucleation of Ag filaments on α-Ag2WO4 crystals, which is driven by an accelerated electron beam from an electron microscope under high vacuum. The growth process and the chemical composition and...

journal_title：Scientific reports

authors： Andrés J,Gracia L,Gonzalez-Navarrete P,Longo VM,Avansi W Jr,Volanti DP,Ferrer MM,Lemos PS,La Porta FA,Hernandes AC,Longo E

更新日期：2014-06-23 00:00:00

abstract：:Airway smooth muscle (ASM) cells exhibit plastic phenotypic behavior marked by reversible modulation and maturation between contractile and proliferative phenotypic states. Integrins are a class of transmembrane proteins that have been implicated as novel therapeutic targets for asthma treatment. We previously showed ...

journal_title：Scientific reports

authors： Teoh CM,Tan SSL,Langenbach SY,Wong AH,Cheong DHJ,Tam JKC,New CS,Tran T

更新日期：2019-07-09 00:00:00

abstract：:Derangement in bone mineral density (BMD) caused by glucocorticoid is well-known. The present study aimed to find key biological pathways associated with low BMD after glucocorticoid treatment in asthmatics using gene expression profiles of peripheral blood cells. We utilized immortalized B cells (IBCs) from 32 childh...

journal_title：Scientific reports

authors： Lee SY,Won HK,Kim BK,Kim SH,Chang YS,Cho SH,Kelly HW,Tantisira KG,Park HW

更新日期：2019-12-27 00:00:00

abstract：:Alzheimer's disease (AD) is a lethal progressive neurological disorder affecting the memory. Recently, US Food and Drug Administration mitigated the standard for drug approval, allowing symptomatic drugs that only improve cognitive deficits to be allowed to accelerate on to clinical trials. Our study focuses on taurin...

journal_title：Scientific reports

authors： Kim HY,Kim HV,Yoon JH,Kang BR,Cho SM,Lee S,Kim JY,Kim JW,Cho Y,Woo J,Kim Y

更新日期：2014-12-12 00:00:00

abstract：:There is a growing need for low-cost, portable technologies for the detection of threats to the environment and human health. Here we propose a label-free, optical whole-cell Escherichia coli biosensor for the detection of 3-phenoxybenzoic acid (3-PBA), a biomarker for monitoring human exposure to synthetic pyrethroid...

journal_title：Scientific reports

authors： Riangrungroj P,Bever CS,Hammock BD,Polizzi KM

更新日期：2019-08-28 00:00:00

abstract：:The ability of wild animals to respond flexibly to anthropogenic environmental changes, including agriculture, is critical to survival in human-impacted habitats. Understanding use of human foods by wildlife can shed light on the acquisition of novel feeding habits and how animals respond to human-driven land-use chan...

journal_title：Scientific reports

authors： McLennan MR,Hockings KJ

更新日期：2014-08-05 00:00:00

abstract：:Anoectochilus roxburghii and Anoectochilus formasanus are the major species of genus Anoectochilus used in traditional Chinese medicine for their abundant content of flavonoids and some other medicinal constituents. In recent years, their wild resources are gradually exhausted due to over-collection and ecological det...

journal_title：Scientific reports

authors： Yang L,Zhang JC,Qu JT,He G,Yu HQ,Li WC,Fu FL

更新日期：2019-12-27 00:00:00