Concentration profiles of ions and particles under hydrodynamic focusing in Y-shaped square microchannel.

Abstract:

:Three-dimensional ion and particle concentrations under hydrodynamic focusing in a Y-shaped square microchannel are numerically simulated to clarify the decrease of the ion concentration along the flow direction within the focused particle stream. The simulation model is theoretically governed by the laminar flow and advection-diffusion equations. The governing equations are solved by the finite volume method. The ion and particle concentration distributions at five cross sections after the confluence of the branch channels are analyzed in 30 cases in which the sheath to sample flow rate ratio Qsh/Qsam and the Reynolds number Re are varied as parameters. The results show that the decrease of the cross-sectional average ion concentration along the flow direction within the particle stream [Formula: see text] is described by the diffusion length during the residence time with a characteristic velocity scale. In addition, the deformation of the particle stream due to inertial effects is described by a scaled Reynolds number that is a function of the flow rate ratio. The simulated particle stream thicknesses are validated by theory and a simple experiment. This paper reveals the relationship between the ion and particle concentrations and the dimensionless parameters for hydrodynamic focusing in the Y-shaped square microchannel under typical conditions.

journal_name

Sci Rep

journal_title

Scientific reports

authors

Sato N,Kawashima D,Takei M

doi

10.1038/s41598-021-82259-4

subject

Has Abstract

pub_date

2021-01-28 00:00:00

pages

2585

issue

1

issn

2045-2322

pii

10.1038/s41598-021-82259-4

journal_volume

11

pub_type

杂志文章
  • Author Correction: High-resolution record reveals climate-driven environmental and sedimentary changes in an active rift.

    abstract::A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper. ...

    journal_title:Scientific reports

    pub_type: 已发布勘误

    doi:10.1038/s41598-019-42749-y

    authors: McNeill LC,Shillington DJ,Carter GDO,Everest JD,Gawthorpe RL,Miller C,Phillips MP,Collier REL,Cvetkoska A,De Gelder G,Diz P,Doan ML,Ford M,Geraga M,Gillespie J,Hemelsdaël R,Herrero-Bervera E,Ismaiel M,Janikian L,Kou

    更新日期:2019-04-19 00:00:00

  • Strain-Engineered Graphene Grown on Hexagonal Boron Nitride by Molecular Beam Epitaxy.

    abstract::Graphene grown by high temperature molecular beam epitaxy on hexagonal boron nitride (hBN) forms continuous domains with dimensions of order 20 μm, and exhibits moiré patterns with large periodicities, up to ~30 nm, indicating that the layers are highly strained. Topological defects in the moiré patterns are observed ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep22440

    authors: Summerfield A,Davies A,Cheng TS,Korolkov VV,Cho Y,Mellor CJ,Foxon CT,Khlobystov AN,Watanabe K,Taniguchi T,Eaves L,Novikov SV,Beton PH

    更新日期:2016-03-01 00:00:00

  • Kaempferol stimulates gene expression of low-density lipoprotein receptor through activation of Sp1 in cultured hepatocytes.

    abstract::A high level of plasma low-density lipoprotein (LDL) cholesterol is considered a risk factor for atherosclerosis. Because the hepatic LDL receptor (LDLR) is essential for clearing plasma LDL cholesterol, activation of LDLR is a promising therapeutic target for patients with atherosclerotic disease. Here we demonstrate...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep24940

    authors: Ochiai A,Miyata S,Iwase M,Shimizu M,Inoue J,Sato R

    更新日期:2016-04-25 00:00:00

  • Elastase levels and activity are increased in dystrophic muscle and impair myoblast cell survival, proliferation and differentiation.

    abstract::In Duchenne muscular dystrophy, progressive loss of muscle tissue is accompanied by fibrosis, chronic inflammation and reduced muscle regenerative capacity. Although much is known about the development of fibrosis and chronic inflammation in muscular dystrophy, less is known about how they are mechanistically linked t...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep24708

    authors: Arecco N,Clarke CJ,Jones FK,Simpson DM,Mason D,Beynon RJ,Pisconti A

    更新日期:2016-05-31 00:00:00

  • Damnacanthal, a noni anthraquinone, inhibits c-Met and is a potent antitumor compound against Hep G2 human hepatocellular carcinoma cells.

    abstract::Damnacanthal, an anthraquinone present in noni plants, targets several tyrosine kinases and has antitumoral effects. This study aims at getting additional insight on the potential of damnacanthal as a natural antitumor compound. The direct effect of damnacanthal on c-Met was tested by in vitro activity assays. Additio...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep08021

    authors: García-Vilas JA,Quesada AR,Medina MA

    更新日期:2015-01-26 00:00:00

  • Realizing Broadband and Invertible Linear-to-circular Polarization Converter with Ultrathin Single-layer Metasurface.

    abstract::The arbitrary control of the polarization states of light has attracted the interest of the scientific community because of the wide range of modern optical applications that such control can afford. However, conventional polarization control setups are bulky and very often operate only within a narrow wavelength rang...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep18106

    authors: Li Z,Liu W,Cheng H,Chen S,Tian J

    更新日期:2015-12-15 00:00:00

  • Two-Dimensional Pnictogen Honeycomb Lattice: Structure, On-Site Spin-Orbit Coupling and Spin Polarization.

    abstract::Because of its novel physical properties, two-dimensional materials have attracted great attention. From first-principle calculations and vibration frequencies analysis, we predict a new family of two-dimensional materials based on the idea of octet stability: honeycomb lattices of pnictogens (N, P, As, Sb, Bi). The b...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep11512

    authors: Lee J,Tian WC,Wang WL,Yao DX

    更新日期:2015-06-30 00:00:00

  • Decreased temperature variance associated with biotic composition enhances coastal shrub encroachment.

    abstract::Regime shift from grasslands to shrub-dominated landscapes occur worldwide driven by altered land-use and climate change, affecting landscape function, biodiversity, and productivity. Warming winter temperatures are a main driver of expansion of the native, evergreen shrub, Morella cerifera, in coastal landscapes. Shr...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-65161-3

    authors: Wood LK,Hays S,Zinnert JC

    更新日期:2020-05-19 00:00:00

  • HIV Subtypes B and C gp120 and Methamphetamine Interaction: Dopaminergic System Implicates Differential Neuronal Toxicity.

    abstract::HIV subtypes or clades differentially induce HIV-associated neurocognitive disorders (HAND) and substance abuse is known to accelerate HIV disease progression. The HIV-1 envelope protein gp120 plays a major role in binding and budding in the central nervous system (CNS) and impacts dopaminergic functions. However, the...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep11130

    authors: Samikkannu T,Rao KVK,Salam AAA,Atluri VSR,Kaftanovskaya EM,Agudelo M,Perez S,Yoo C,Raymond AD,Ding H,Nair MPN

    更新日期:2015-06-09 00:00:00

  • Hair follicle germs containing vascular endothelial cells for hair regenerative medicine.

    abstract::Hair regenerative medicine has emerged as a promising approach for the treatment of severe hair loss. Recent advances in three-dimensional tissue engineering, such as formation of hair follicle germs (HFGs), have considerably improved hair regeneration after transplantation in animal models. Here, we proposed an appro...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-79722-z

    authors: Kageyama T,Chun YS,Fukuda J

    更新日期:2021-01-12 00:00:00

  • Radiobrominated benzimidazole-quinoline derivatives as Platelet-derived growth factor receptor beta (PDGFRβ) imaging probes.

    abstract::Platelet-derived growth factor receptor beta (PDGFRβ) affects in numerous human cancers and has been recognized as a promising molecular target for cancer therapies. The overexpression of PDGFRβ could be a biomarker for cancer diagnosis. Radiolabeled ligands having high affinity for the molecular target could be usefu...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-28529-0

    authors: Effendi N,Mishiro K,Takarada T,Makino A,Yamada D,Kitamura Y,Shiba K,Kiyono Y,Odani A,Ogawa K

    更新日期:2018-07-10 00:00:00

  • Complex patterns arise through spontaneous symmetry breaking in dense homogeneous networks of neural oscillators.

    abstract::There has been much interest in understanding collective dynamics in networks of brain regions due to their role in behavior and cognitive function. Here we show that a simple, homogeneous system of densely connected oscillators, representing the aggregate activity of local brain regions, can exhibit a rich variety of...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep22074

    authors: Singh R,Menon SN,Sinha S

    更新日期:2016-02-26 00:00:00

  • Common variants of T-cells contribute differently to phenotypic variation in sarcoidosis.

    abstract::The involvement of the immune system, particularly the role of T-cells, in sarcoidosis is unclear. The existence of higher CD4+ T-cells and increased CD4/CD8 ratio may indicate a pathogenic role of T-cells in the disease. In this study, we quantified the contribution of T-cells associated variants and of CD4/CD8 ratio...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-05754-7

    authors: Rivera NV,Hagemann-Jensen M,Ferreira MAR,Kullberg S,Eklund A,Martin NG,Padyukov L,Grunewald J

    更新日期:2017-07-17 00:00:00

  • Linkage Between Hourly Precipitation Events and Atmospheric Temperature Changes over China during the Warm Season.

    abstract::We investigated changes in the temporospatial features of hourly precipitation during the warm season over mainland China. The frequency and amount of hourly precipitation displayed latitudinal zonation, especially for light and moderate precipitation, which showed successive downward change over time in northeastern ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep22543

    authors: Miao C,Sun Q,Borthwick AG,Duan Q

    更新日期:2016-03-02 00:00:00

  • Glutathione S-transferase (GST) of American Cockroach, Periplaneta americana: Classes, Isoforms, and Allergenicity.

    abstract::Insect glutathione S-transferases (GSTs) play important roles in insecticide/drug resistance and stress response. Medically, GSTs of house dust mites (Dermatophagoides pteronyssinus and Blomia tropicalis) and German cockroach (Blattella germanica) are human allergens. In this study, classes, isoforms and B-cell and al...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-18759-z

    authors: Sookrung N,Reamtong O,Poolphol R,Indrawattana N,Seesuay W,Saelim N,Tantilipikorn P,Bunnag C,Chaicumpa W,Tungtrongchitr A

    更新日期:2018-01-11 00:00:00

  • Dual Ionic and Organic Nature of Ionic Liquids.

    abstract::Inherited the advantages of inorganic salts and organic solvents, ionic liquids (ILs) exhibit many superior properties allowing them promising green solvents for the future. Although it has been widely acknowledged that the unique features of ILs originate from their dual ionic and organic nature, its microscopic phys...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep19644

    authors: Shi R,Wang Y

    更新日期:2016-01-19 00:00:00

  • Shallow carbon storage in ancient buried thermokarst in the South Kara Sea.

    abstract::Geophysical data from the South Kara Sea reveal U-shaped erosional structures buried beneath the 50-250 m deep seafloor of the continental shelf across an area of ~32 000 km2. These structures are interpreted as thermokarst, formed in ancient yedoma terrains during Quaternary interglacial periods. Based on comparison ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-32826-z

    authors: Portnov A,Mienert J,Winsborrow M,Andreassen K,Vadakkepuliyambatta S,Semenov P,Gataullin V

    更新日期:2018-09-25 00:00:00

  • Magnetization switching of a perpendicular nanomagnet induced by vertical nonlocal injection of pure spin current.

    abstract::Injection of pure spin current using a nonlocal geometry is a promising method for controlling magnetization in spintronic devices from the viewpoints of increasing freedom in device structure and avoiding problems related to charge current. Here, we report an experimental demonstration of magnetization switching of a...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-56082-x

    authors: Suto H,Nagasawa T,Kanao T,Yamada K,Mizushima K

    更新日期:2019-12-20 00:00:00

  • Network-based Responses to the Psychomotor Vigilance Task during Lapses in Adolescents after Short and Extended Sleep.

    abstract::Neuroimaging studies of the Psychomotor Vigilance Task (PVT) have revealed brain regions involved in attention lapses in sleep-deprived and well-rested adults. Those studies have focused on individual brain regions, rather than integrated brain networks, and have overlooked adolescence, a period of ongoing brain devel...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-50180-6

    authors: DiFrancesco MW,Van Dyk T,Altaye M,Drummond SPA,Beebe DW

    更新日期:2019-09-26 00:00:00

  • Pyridoxamine improves survival and limits cardiac dysfunction after MI.

    abstract::Advanced glycation end products (AGEs) play a key role in the progression of heart failure. Whether treatments limiting AGEs formation would prevent adverse left ventricular remodeling after myocardial infarction (MI) remain unknown. We investigated whether pyridoxamine (PM) could limit adverse cardiac outcome in MI. ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-16255-y

    authors: Deluyker D,Ferferieva V,Driesen RB,Verboven M,Lambrichts I,Bito V

    更新日期:2017-11-22 00:00:00

  • Spatial-sweep steady-state pattern electroretinography can detect subtle differences in visual function among healthy adults.

    abstract::We aimed to establish a highly sensitive method for measuring visual function using spatial-sweep steady-state pattern electroretinography (swpPERG). Overall, 35 eyes of 35 healthy adults (18 men; mean age, 32.3 years) were examined using swpPERG, and the data were recorded using spatial-patterned and contrast-reverse...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-54606-z

    authors: Minami S,Nagai N,Suzuki M,Kurihara T,Sonobe H,Watanabe K,Shinoda H,Takagi H,Tsubota K,Ozawa Y

    更新日期:2019-12-02 00:00:00

  • PDGFRA gene, maternal binge drinking and obstructive heart defects.

    abstract::Obstructive heart defects (OHDs) are a major health concern worldwide. The platelet-derived growth factor (PDGF) genes are known to have regulatory functions that are essential for proper heart development. In a zebrafish model, Pdgfra was further demonstrated to interact with ethanol during craniofacial development. ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-29160-9

    authors: Tang X,Eberhart JK,Cleves MA,Li J,Li M,MacLeod S,Nembhard WN,Hobbs CA

    更新日期:2018-07-23 00:00:00

  • Quasi-planktonic behavior of foraging top marine predators.

    abstract::Monitoring marine top predators is fundamental for assessing the health and functioning of open ocean ecosystems. Although recently tracking observations have substantially increased, factors determining the horizontal exploration of the ocean by marine predators are still largely unknown, especially at the scale of b...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep18063

    authors: Della Penna A,De Monte S,Kestenare E,Guinet C,d'Ovidio F

    更新日期:2015-12-15 00:00:00

  • Triazophos (TAP) removal in horizontal subsurface flow constructed wetlands (HSCWs) and its accumulation in plants and substrates.

    abstract::Triazophos (TAP) is a widely used phosphorus pesticide in China that possesses a potential risk for water pollution. We have studied the removal efficiency of TAP using pilot-scale horizontal subsurface flow constructed wetlands (HSCWs) as well as the contribution of plants, substrates and other pathways to its remova...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-05874-0

    authors: Wu J,Li Z,Wu L,Zhong F,Cui N,Dai Y,Cheng S

    更新日期:2017-07-14 00:00:00

  • Carbon wrapped hierarchical Li3V2(PO4)3 microspheres for high performance lithium ion batteries.

    abstract::Nanomaterials are extensively studied in electrochemical energy storage and conversion systems because of their structural advantages. However, their volumetric energy density still needs improvement due to the high surface area, especially the carbon based nanocomposites. Constructing hierarchical micro-scaled materi...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep33682

    authors: Liang S,Tan Q,Xiong W,Tang Y,Tan X,Huang L,Pan A,Cao G

    更新日期:2016-09-21 00:00:00

  • A multitarget approach to drug discovery inhibiting Mycobacterium tuberculosis PyrG and PanK.

    abstract::Mycobacterium tuberculosis, the etiological agent of the infectious disease tuberculosis, kills approximately 1.5 million people annually, while the spread of multidrug-resistant strains is of great global concern. Thus, continuous efforts to identify new antitubercular drugs as well as novel targets are crucial. Rece...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-21614-4

    authors: Chiarelli LR,Mori G,Orena BS,Esposito M,Lane T,de Jesus Lopes Ribeiro AL,Degiacomi G,Zemanová J,Szádocka S,Huszár S,Palčeková Z,Manfredi M,Gosetti F,Lelièvre J,Ballell L,Kazakova E,Makarov V,Marengo E,Mikusova K,Col

    更新日期:2018-02-16 00:00:00

  • Excitability regulation in the dorsomedial prefrontal cortex during sustained instructed fear responses: a TMS-EEG study.

    abstract::Threat detection is essential for protecting individuals from adverse situations, in which a network of amygdala, limbic regions and dorsomedial prefrontal cortex (dmPFC) regions are involved in fear processing. Excitability regulation in the dmPFC might be crucial for fear processing, while abnormal patterns could le...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-32781-9

    authors: Gonzalez-Escamilla G,Chirumamilla VC,Meyer B,Bonertz T,von Grotthus S,Vogt J,Stroh A,Horstmann JP,Tüscher O,Kalisch R,Muthuraman M,Groppa S

    更新日期:2018-09-28 00:00:00

  • Phenotypic and Transcriptomic Analysis of Two Pinellia ternata Varieties T2 line and T2Plus line.

    abstract::Pinellia (Pinellia ternata (Thunb.) Breit.), as important medicinal plant, has been used to treat various ailments for a long time. The sixteen ploid plant (2n = 16 * 13 = 208) Pinellia T2Plus line was obtained from an octoploid (2n = 8 * 13 = 104) T2 line by chromosome-doubling technique. Compared with T2 line, the c...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-61512-2

    authors: Lu J,Liu JN,Sarsaiya S,Duns GJ,Han J,Jin L,Chen J

    更新日期:2020-03-12 00:00:00

  • Exploring the effects of anodal and cathodal high definition transcranial direct current stimulation targeting the dorsal anterior cingulate cortex.

    abstract::The dorsal anterior cingulate cortex (dACC) has been identified as a core region affected by many disorders, representing a promising target for neuromodulation. High Definition-transcranial Direct Current Stimulation (HD-tDCS) is a non-invasive neuromodulation technique that has already shown promising outcomes and h...

    journal_title:Scientific reports

    pub_type: 杂志文章,随机对照试验

    doi:10.1038/s41598-018-22730-x

    authors: To WT,Eroh J,Hart J Jr,Vanneste S

    更新日期:2018-03-13 00:00:00

  • A longitudinal study of semen quality among Chinese sperm donor candidates during the past 11 years.

    abstract::Studies suggest that semen quality is declining globally, however, the debate remains open due to the possible effects of ethnic and geographical differences. This study aimed to explore whether semen quality of sperm donor candidates has changed in Henan Province, China from 2009 to 2019. In this retrospective study,...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-67707-x

    authors: Liu J,Dai Y,Li Y,Yuan E,Wang Q,Wang X,Guan Y

    更新日期:2020-07-01 00:00:00