听力与言语-语言病理学

行为科学

医学伦理学

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  • A novel acid polysaccharide from Boletus edulis: extraction, characteristics and antitumor activities in vitro.

    abstract::A novel cold-water-soluble polysaccharide (BEP), with a molecular weight of 6.0 × 106 Da, was isolated from Boletus edulis. BEP consists of galactose, glucose, xylose, mannose, glucuronic, and galacturonic acid in a ratio of 0.34:0.28:0.28:2.57:1.00:0.44. The IR results showed that BEP was an acid polysaccharide, cont...

    journal_title:Glycoconjugate journal

    pub_type: 杂志文章

    doi:10.1007/s10719-021-09972-0

    authors: Meng T,Yu SS,Ji HY,Xu XM,Liu AJ

    更新日期:2021-01-28 00:00:00

  • N- and O-glycosylation patterns and functional testing of CGB7 versus CGB3/5/8 variants of the human chorionic gonadotropin (hCG) beta subunit.

    abstract::The classical function of human chorionic gonadotropin (hCG) is its role in supporting pregnancy. hCG is a dimer consisting of two highly glycosylated subunits, alpha (CGA) and beta (CGB). The beta-hCG protein is encoded by CGB3, CGB5, CGB7 and CGB8 genes. CGB3, 5 and 8 code for an identical protein, CGB3/5/8, whereas...

    journal_title:Glycoconjugate journal

    pub_type: 杂志文章

    doi:10.1007/s10719-020-09936-w

    authors: Biskup K,Blanchard V,Castillo-Binder P,Alexander H,Engeland K,Schug S

    更新日期:2020-10-01 00:00:00

  • Browning and pigmentation in food through the Maillard reaction.

    abstract::The Maillard reaction was discovered in 1912 by Louis C. Maillard when he observed the browning phenomena with aroma formation in a heated solution containing a sugar and an amino acid. The Maillard reaction starts from the reactions between carbonyl groups of various sugars and amino groups of amino acids/ proteins, ...

    journal_title:Glycoconjugate journal

    pub_type: 杂志文章,评审

    doi:10.1007/s10719-020-09943-x

    authors: Murata M

    更新日期:2020-09-10 00:00:00

  • Identification of lipid raft glycoproteins obtained from boar spermatozoa.

    abstract::The surface of the spermatozoa is coated with glycoproteins the redistribution of which during in vitro capacitation plays a key role in the subsequent fertilization process. Lipid rafts are membrane microdomains involved in signal transduction through receptors and include or recruit specific types of proteins and gl...

    journal_title:Glycoconjugate journal

    pub_type: 杂志文章

    doi:10.1007/s10719-020-09924-0

    authors: López-Salguero JB,Fierro R,Michalski JC,Jiménez-Morales I,Lefebvre T,Mondragón-Payne O,Baldini SF,Vercoutter-Edouart AS,González-Márquez H

    更新日期:2020-08-01 00:00:00

  • The preparation of a cold-water soluble polysaccharide from Grifola frondosa and its inhibitory effects on MKN-45 cells.

    abstract::In this study, a novel water soluble polysaccharide (named GFP-4) was extracted from Grifola frondosa at 4 oC, and its preliminary structure and inhibitory effects on human gastric carcinoma MKN-45 cells through the Fas/FasL death receptor apoptosis pathway were investigated. High-performance gel permeation chromatogr...

    journal_title:Glycoconjugate journal

    pub_type: 杂志文章

    doi:10.1007/s10719-020-09932-0

    authors: Liu C,Ji HY,Wu P,Yu J,Liu AJ

    更新日期:2020-08-01 00:00:00

  • Effects of extraction methods on physicochemical properties and hypoglycemic activities of polysaccharides from coarse green tea.

    abstract::Coarse tea is made of mature tea plant (Camellia sinensis L.) shoots and is generally discarded as a worthless crop product, but has been proved an excellent material for the treatment of diabetes. This study aims to evaluate the effects of the extraction techniques WE (water extraction), UAE (ultrasound-assisted extr...

    journal_title:Glycoconjugate journal

    pub_type: 杂志文章

    doi:10.1007/s10719-019-09901-2

    authors: Zhu J,Chen Z,Zhou H,Yu C,Han Z,Shao S,Hu X,Wei X,Wang Y

    更新日期:2020-04-01 00:00:00

  • ALG12-CDG: novel glycophenotype insights endorse the molecular defect.

    abstract::Congenital disorders of glycosylation (CDG) are genetic diseases characterized by deficient synthesis (CDG type I) and/or abnormal processing (CDG type II) of glycan moieties linked to protein and lipids. The impact of the molecular defects on protein glycosylation and in turn on the clinical phenotypes of patients wi...

    journal_title:Glycoconjugate journal

    pub_type: 杂志文章

    doi:10.1007/s10719-019-09890-2

    authors: Sturiale L,Bianca S,Garozzo D,Terracciano A,Agolini E,Messina A,Palmigiano A,Esposito F,Barone C,Novelli A,Fiumara A,Jaeken J,Barone R

    更新日期:2019-12-01 00:00:00

  • Stage-specific embryonic antigen-4 is a histological marker reflecting the malignant behavior of prostate cancer.

    abstract::Stage-specific embryonic antigen-4 (SSEA-4), a specific marker for pluripotent stem cells, plays an important role in the malignant behavior of several cancers. Here, SSEA-4 expression was evaluated by immunohistochemistry using monoclonal antibody RM1 specific to SSEA-4 in 181 and 117 prostate cancer (PC) specimens o...

    journal_title:Glycoconjugate journal

    pub_type: 杂志文章

    doi:10.1007/s10719-019-09882-2

    authors: Nakamura Y,Miyata Y,Matsuo T,Shida Y,Hakariya T,Ohba K,Taima T,Ito A,Suda T,Hakomori SI,Saito S,Sakai H

    更新日期:2019-10-01 00:00:00

  • Analysis of Heparan sulfate/heparin from Colla corii asini by liquid chromatography-electrospray ion trap mass spectrometry.

    abstract::Colla corii asini (CCA) made from donkey-hide has been widely used as a health-care food and an ingredient of traditional Chinese medicine. Heparan sulfate (HS)/heparin is a structurally complex class of glycosaminoglycans (GAGs) that have been implicated in a wide range of biological activities. However, their presen...

    journal_title:Glycoconjugate journal

    pub_type: 杂志文章

    doi:10.1007/s10719-019-09868-0

    authors: Du J,Liu S,Liang Q,Lin J,Jiang L,Chen F,Wei Z

    更新日期:2019-06-01 00:00:00

  • Quantitation of Glycopeptides by ESI/MS - size of the peptide part strongly affects the relative proportions and allows discovery of new glycan compositions of Ceruloplasmin.

    abstract::Significant changes of glycan structures are observed in humans if diseases like cancer, arthritis or inflammation are present. Thus, interest in biomarkers based on glycan structures has rapidly emerged in recent years and monitoring disease specific changes of glycosylation and their quantification is of great inter...

    journal_title:Glycoconjugate journal

    pub_type: 杂志文章

    doi:10.1007/s10719-018-9852-5

    authors: Baerenfaenger M,Moritz M,Meyer B

    更新日期:2019-02-01 00:00:00

  • Chemical characterization of the milk oligosaccharides of some Artiodactyla species including giraffe (Giraffa camelopardalis), sitatunga (Tragelaphus spekii), deer (Cervus nippon yesoensis) and water buffalo (Bubalus bubalis).

    abstract::Mammalian milk/colostrum usually contains oligosaccharides along with the predominant disaccharide lactose. It has been found that the number and identity of these milk oligosaccharides varies among mammalian species. Oligosaccharides predominate over lactose in the milk/colostrum of Arctoidea species (Carnivora), whe...

    journal_title:Glycoconjugate journal

    pub_type: 杂志文章

    doi:10.1007/s10719-018-9849-0

    authors: Mineguchi Y,Miyoshi M,Taufik E,Kawamura A,Asakawa T,Suzuki I,Souma K,Okubo M,Saito T,Fukuda K,Asakuma S,Urashima T

    更新日期:2018-12-01 00:00:00

  • Identification and characterization of the 4-epimerase AglW from the archaeon Methanococcus maripaludis.

    abstract::Archaea are ubiquitous single-cell microorganisms that have often adapted to harsh conditions and play important roles in biogeochemical cycles with potential applications in biotechnology. Methanococcus maripaludis, a methane-producing archaeon, is motile through multiple archaella on its cell surface. The major stru...

    journal_title:Glycoconjugate journal

    pub_type: 杂志文章

    doi:10.1007/s10719-018-9845-4

    authors: Sharma S,Ding Y,Jarrell KF,Brockhausen I

    更新日期:2018-12-01 00:00:00

  • Enrichment and characterization of a bacterial mixture capable of utilizing C-mannosyl tryptophan as a carbon source.

    abstract::C-Mannosylation, a protein-modification found in various eukaryotes, involves the attachment of a single mannose molecule to selected tryptophan residues of proteins. Since C-mannosyl tryptophan (CMW) was detected in human urine, it is generally thought that CMW is not catabolized inside our body and instead is excret...

    journal_title:Glycoconjugate journal

    pub_type: 杂志文章

    doi:10.1007/s10719-017-9807-2

    authors: Hossain TJ,Manabe S,Ito Y,Iida T,Kosono S,Ueda K,Hosomi A,Inoue D,Suzuki T

    更新日期:2018-04-01 00:00:00

  • Biomolecular analysis of matrix proteoglycans as biomarkers in non small cell lung cancer.

    abstract::Matrix proteoglycans (PGs) have shown promise as biomarker in malignancies. We employed agarose gel eletrophoresis, quantitative real- time reverse transcription-polymerase chain reaction and immunohistochemistry to evaluate the content of sulfated glicosaminoglycans (chondroitin sulfate and heparan sulfate) and expre...

    journal_title:Glycoconjugate journal

    pub_type: 杂志文章

    doi:10.1007/s10719-018-9815-x

    authors: Rangel MP,de Sá VK,Prieto T,Martins JRM,Olivieri ER,Carraro D,Takagaki T,Capelozzi VL

    更新日期:2018-04-01 00:00:00

  • Identification and biochemical characterization of WbwB, a novel UDP-Gal: Neu5Ac-R α1,4-galactosyltransferase from the intestinal pathogen Escherichia coli serotype O104.

    abstract::The intestinal pathogen Escherichia coli serotype O104:H4 (ECO104) can cause bloody diarrhea and haemolytic uremic syndrome. The ECO104 O antigen has the unique repeating unit structure [4Galα1-4Neu5,7,9Ac3α2-3Galβ1-3GalNAcβ1-], which includes the mammalian sialyl-T antigen as an internal structure. Previously, we ide...

    journal_title:Glycoconjugate journal

    pub_type: 杂志文章

    doi:10.1007/s10719-017-9799-y

    authors: Czuchry D,Szarek WA,Brockhausen I

    更新日期:2018-02-01 00:00:00

  • Enzymatic synthesis of fucose-containing galacto-oligosaccharides using β-galactosidase and identification of novel disaccharide structures.

    abstract::Fucosylated oligosaccharides have an important role in maintaining a healthy immune system and homeostatic gut microflora. This study employed a commercial β-galactosidase in the production of fucose-containing galacto-oligosaccharides (fGOS) from lactose and fucose. The production was optimized using experiment desig...

    journal_title:Glycoconjugate journal

    pub_type: 杂志文章

    doi:10.1007/s10719-017-9794-3

    authors: Usvalampi A,Maaheimo H,Tossavainen O,Frey AD

    更新日期:2018-02-01 00:00:00

  • Epigenetic regulation of ganglioside expression in neural stem cells and neuronal cells.

    abstract::The structural diversity and localization of cell surface glycosphingolipids (GSLs), including gangliosides, in glycolipid-enriched microdomains (GEMs, also known as lipid rafts) render them ideally suited to play important roles in mediating intercellular recognition, interactions, adhesion, receptor function, and si...

    journal_title:Glycoconjugate journal

    pub_type: 杂志文章,评审

    doi:10.1007/s10719-016-9719-6

    authors: Itokazu Y,Tsai YT,Yu RK

    更新日期:2017-12-01 00:00:00

  • Heparan sulfate proteoglycans as key regulators of the mesenchymal niche of hematopoietic stem cells.

    abstract::The complex microenvironment that surrounds hematopoietic stem cells (HSCs) in the bone marrow niche involves different coordinated signaling pathways. The stem cells establish permanent interactions with distinct cell types such as mesenchymal stromal cells, osteoblasts, osteoclasts or endothelial cells and with secr...

    journal_title:Glycoconjugate journal

    pub_type: 杂志文章,评审

    doi:10.1007/s10719-017-9773-8

    authors: Papy-Garcia D,Albanese P

    更新日期:2017-06-01 00:00:00

  • MDA-MB-231 breast cancer cell viability, motility and matrix adhesion are regulated by a complex interplay of heparan sulfate, chondroitin-/dermatan sulfate and hyaluronan biosynthesis.

    abstract::Proteoglycans and glycosaminoglycans modulate numerous cellular processes relevant to tumour progression, including cell proliferation, cell-matrix interactions, cell motility and invasive growth. Among the glycosaminoglycans with a well-documented role in tumour progression are heparan sulphate, chondroitin/dermatan ...

    journal_title:Glycoconjugate journal

    pub_type: 杂志文章

    doi:10.1007/s10719-016-9735-6

    authors: Viola M,Brüggemann K,Karousou E,Caon I,Caravà E,Vigetti D,Greve B,Stock C,De Luca G,Passi A,Götte M

    更新日期:2017-06-01 00:00:00

  • 19F labelled glycosaminoglycan probes for solution NMR and non-linear (CARS) microscopy.

    abstract::Studying polysaccharide-protein interactions under physiological conditions by conventional techniques is challenging. Ideally, macromolecules could be followed by both in vitro spectroscopy experiments as well as in tissues using microscopy, to enable a proper comparison of results over these different scales but, of...

    journal_title:Glycoconjugate journal

    pub_type: 杂志文章

    doi:10.1007/s10719-016-9723-x

    authors: Lima MA,Cavalheiro RP,M Viana G,Meneghetti MCZ,Rudd TR,Skidmore MA,Powell AK,Yates EA

    更新日期:2017-06-01 00:00:00

  • Glycosylation: a hallmark of cancer?

    abstract::The hallmarks of cancer are characterized by functional capabilities that allow cancer cells to survive, proliferate and disseminate during the multistep tumorigenesis. Cancer being a cellular disease, changes in cellular glycoproteins play an important role in malignant transformation and cancer progression. The pres...

    journal_title:Glycoconjugate journal

    pub_type: 杂志文章,评审

    doi:10.1007/s10719-016-9755-2

    authors: Vajaria BN,Patel PS

    更新日期:2017-04-01 00:00:00

  • Podocalyxin as a major pluripotent marker and novel keratan sulfate proteoglycan in human embryonic and induced pluripotent stem cells.

    abstract::Podocalyxin (PC) was first identified as a heavily sialylated transmembrane protein of glomerular podocytes. Recent studies suggest that PC is a remarkable glycoconjugate that acts as a universal glyco-carrier. The glycoforms of PC are responsible for multiple functions in normal tissue, human cancer cells, human embr...

    journal_title:Glycoconjugate journal

    pub_type: 杂志文章,评审

    doi:10.1007/s10719-016-9757-0

    authors: Toyoda H,Nagai Y,Kojima A,Kinoshita-Toyoda A

    更新日期:2017-04-01 00:00:00

  • Purification and sequence characterization of chondroitin sulfate and dermatan sulfate from fishes.

    abstract::Chondroitin sulfate (CS) and dermatan sulfate (DS) were extracted and purified from skins or bones of salmon (Salmo salar), snakehead (Channa argus), monkfish (Lophius litulon) and skipjack tuna (Katsuwonus pelamis). Size, structural sequences and sulfate groups of oligosaccharides in the purified CS and DS could be c...

    journal_title:Glycoconjugate journal

    pub_type: 杂志文章

    doi:10.1007/s10719-016-9759-y

    authors: Lin N,Mo X,Yang Y,Zhang H

    更新日期:2017-04-01 00:00:00

  • Clinicopathological significance of ganglioside DSGb5 expression in renal cell carcinoma.

    abstract::Disialosyl globopentaosylceramide (DSGb5) is a ganglioside originally isolated from tissue extracts of renal cell carcinoma (RCC) with metastasis. Previous in vitro experiments have suggested that DSGb5 promotes metastasis by enhancing the migration of RCC cells and downregulating NK cell cytotoxicity against RCC cell...

    journal_title:Glycoconjugate journal

    pub_type: 杂志文章

    doi:10.1007/s10719-017-9763-x

    authors: Itoh J,Ito A,Shimada S,Kawasaki Y,Kakoi N,Saito H,Mitsuzuka K,Watanabe M,Satoh M,Saito S,Arai Y

    更新日期:2017-04-01 00:00:00

  • Structures and gene clusters of the O-specific polysaccharides of the lipopolysaccharides of Escherichia coli O69 and O146 containing glycolactilic acids: ether conjugates of D-GlcNAc and D-Glc with (R)- and (S)-lactic acid.

    abstract::Based on the O-specific polysaccharides of the lipopolysaccharides (O-polysaccharides, O-antigens), strains of a clonal species Escherichia coli are classified into 184 O serogroups. In this work, structures of the O-polysaccharides of E. coli O69 and O146 were elucidated and gene clusters for their biosynthesis were ...

    journal_title:Glycoconjugate journal

    pub_type: 杂志文章

    doi:10.1007/s10719-016-9730-y

    authors: Knirel YA,Guo X,Senchenkova SN,Perepelov AV,Liu B,Shashkov AS

    更新日期:2017-02-01 00:00:00

  • Site-specific characterization of N-linked glycosylation in human urinary glycoproteins and endogenous glycopeptides.

    abstract::Glycosylation is a very important post-translational modification involved in various cellular processes, such as cell adhesion, signal transduction and immune response. Urine is a rich source of glycoproteins and attractive biological fluid for biomarker discovery, owing to its availability, ease of collection, and c...

    journal_title:Glycoconjugate journal

    pub_type: 杂志文章

    doi:10.1007/s10719-016-9677-z

    authors: Kawahara R,Saad J,Angeli CB,Palmisano G

    更新日期:2016-12-01 00:00:00

  • Evaluation of an amino acid residue critical for the specificity and activity of human Gb3/CD77 synthase.

    abstract::Human Gb3/CD77 synthase (α1,4-galactosyltransferase) is the only known glycosyltransferase that changes acceptor specificity because of a point mutation. The enzyme, encoded by A4GALT locus, is responsible for biosynthesis of Gal(α1-4)Gal moiety in Gb3 (CD77, Pk antigen) and P1 glycosphingolipids. We showed before tha...

    journal_title:Glycoconjugate journal

    pub_type: 杂志文章

    doi:10.1007/s10719-016-9716-9

    authors: Kaczmarek R,Mikolajewicz K,Szymczak K,Duk M,Majorczyk E,Krop-Watorek A,Buczkowska A,Czerwinski M

    更新日期:2016-12-01 00:00:00

  • DNA-aptamers raised against AGEs as a blocker of various aging-related disorders.

    abstract::A non-enzymatic reaction between sugars or aldehydes and the amino groups of proteins, lipids and nucleic acids contributes to the aging of macromolecules, which could impair their structural integrity and function. This process begins with the conversion of reversible Schiff base adducts, and then to more stable, cov...

    journal_title:Glycoconjugate journal

    pub_type: 杂志文章

    doi:10.1007/s10719-016-9682-2

    authors: Yamagishi S,Taguchi K,Fukami K

    更新日期:2016-08-01 00:00:00

  • Glycoproteomic studies of IgE from a novel hyper IgE syndrome linked to PGM3 mutation.

    abstract::Glycans serve as important regulators of antibody activities and half-lives. IgE is the most heavily glycosylated antibody, but in comparison to other antibodies little is known about its glycan structure function relationships. We therefore describe the site specific IgE glycosylation from a patient with a novel hype...

    journal_title:Glycoconjugate journal

    pub_type: 杂志文章

    doi:10.1007/s10719-015-9638-y

    authors: Wu G,Hitchen PG,Panico M,North SJ,Barbouche MR,Binet D,Morris HR,Dell A,Haslam SM

    更新日期:2016-06-01 00:00:00

  • A case for protein-level and site-level specificity in glycoproteomic studies of disease.

    abstract::Abnormal glycosylation of proteins is known to be either resultant or causative of a variety of diseases. This makes glycoproteins appealing targets as potential biomarkers and focal points of molecular studies on the development and progression of human ailment. To date, a majority of efforts in disease glycoproteomi...

    journal_title:Glycoconjugate journal

    pub_type: 杂志文章,评审

    doi:10.1007/s10719-016-9663-5

    authors: Schumacher KN,Dodds ED

    更新日期:2016-06-01 00:00:00

  • Metabolic fate of milk glycosaminoglycans in breastfed and formula fed newborns.

    abstract::In this study, the content, structure and residual percentages of glycosaminoglycans (GAGs) in the feces of seven breastfed newborns after ingesting a known amount of milk were studied. A comparison was made with five newborns fed with formula milk. Characterization of GAGs from milk and feces samples was performed ac...

    journal_title:Glycoconjugate journal

    pub_type: 临床试验,杂志文章

    doi:10.1007/s10719-016-9655-5

    authors: Maccari F,Mantovani V,Gabrielli O,Carlucci A,Zampini L,Galeazzi T,Galeotti F,Coppa GV,Volpi N

    更新日期:2016-04-01 00:00:00

  • Quantification of sialic acids in red meat by UPLC-FLD using indoxylsialosides as internal standards.

    abstract::Herein we describe a UPLC-FLD-based method for the quantification of the sialic acid content of red meat, using a synthetic neuraminic acid derivative as an internal standard. X-Gal-α-2,6-N-propionylneuraminic acid was synthesized via a chemoenzymatic pathway and its hydrolytic stability was characterized. Known quant...

    journal_title:Glycoconjugate journal

    pub_type: 杂志文章

    doi:10.1007/s10719-016-9659-1

    authors: Yao HL,Conway LP,Wang MM,Huang K,Liu L,Voglmeir J

    更新日期:2016-04-01 00:00:00

  • An expeditious synthesis of blood-group antigens, ABO histo-blood group type II antigens and xenoantigen oligosaccharides with amino type spacer-arms.

    abstract::Blood group oligosaccharides are one of the most clinically important antigen families and they may also act as secondary ligands for bacterial toxins from Escherichia coli and Vibrio cholerae. Herein we report the synthesis of spacered (sp = CH2CH2CH2NH2) glycosides of A antigen {α-D-GalNAc-(l→3)-[α-L-Fuc-(l→2)]-β-D-...

    journal_title:Glycoconjugate journal

    pub_type: 杂志文章

    doi:10.1007/s10719-015-9635-1

    authors: Karki G,Mishra VN,Mandal PK

    更新日期:2016-02-01 00:00:00

  • Multiple lectin assays for detecting glyco-alteration of serum GP73 in liver diseases.

    abstract::Serum GP73 is a functional resident Golgi type II membrane protein with three potential N-glycosylation sites. In this study, we used multiple lectin assays to analyze glycan patterns of serum GP73 and evaluated its diagnostic value for distinguishing hepatocellular carcinoma (HCC) from liver cirrhosis (LC). Firstly, ...

    journal_title:Glycoconjugate journal

    pub_type: 杂志文章

    doi:10.1007/s10719-015-9614-6

    authors: Jiang K,Shang S,Li W,Guo K,Qin X,Zhang S,Liu Y

    更新日期:2015-12-01 00:00:00

  • Hypoxia remodels the composition of the constituent ceramide species of HexCer and Hex2Cer with phytosphingosine and hydroxy fatty acids in human colon cancer LS174T cells.

    abstract::Oxygen-requiring enzymes, such as Δ4-desaturase (dihydroceramide desaturase), sphingolipid Δ4-desaturase/C-4-hydroxylase, and fatty acid 2-hydroxylase are involved in ceramide synthesis. We prepared free ceramides, sphingomyelins and glycosphingolipids (GSLs) from cancer cells cultivated under conditions of normoxia a...

    journal_title:Glycoconjugate journal

    pub_type: 杂志文章

    doi:10.1007/s10719-015-9607-5

    authors: Tanaka K,Tamiya-Koizumi K,Yamada M,Murate T,Kannagi R,Kyogashima M

    更新日期:2015-11-01 00:00:00

  • Stereoselective synthesis of UDP-2-(2-ketopropyl)galactose aided by di-tert-butylsilylene protecting group.

    abstract::UDP-2-(2-ketopropyl)galactose (1) has been utilized as a valuable probe for profiling proteins modified by O-GlcNAc. In this work, we developed a protocol for efficient synthesis of 1. Thus, 2-methallylgalactose derivative 11, a synthetic intermediate for the compound 1, was prepared by stereoselective iodination and ...

    journal_title:Glycoconjugate journal

    pub_type: 杂志文章

    doi:10.1007/s10719-015-9581-y

    authors: Sakamoto Y,Ohta T,Ito Y

    更新日期:2015-10-01 00:00:00

  • Glycan microarrays of fluorescently-tagged natural glycans.

    abstract::This review discusses the challenges facing research in 'functional glycomics' and the novel technologies that are being developed to advance the field. The structural complexity of glycans and glycoconjugates makes studies of both their structures and recognition difficult. However, these intricate structures can be ...

    journal_title:Glycoconjugate journal

    pub_type: 杂志文章,评审

    doi:10.1007/s10719-015-9584-8

    authors: Song X,Heimburg-Molinaro J,Smith DF,Cummings RD

    更新日期:2015-10-01 00:00:00

  • Salivary glyco-sialylation changes monitors oral carcinogenesis.

    abstract::Alterations in cell membrane glycosylation play important role in oral carcinogenesis. The present study evaluated salivary sialylation changes i.e. total sialic acid (TSA), sialidase activity, linkage specific (α2-3 and α2-6) sialoproteins and sialyl transferase (ST) activity in controls, patients with oral precancer...

    journal_title:Glycoconjugate journal

    pub_type: 杂志文章

    doi:10.1007/s10719-014-9561-7

    authors: Vajaria BN,Patel KR,Begum R,Patel JB,Shah FD,Joshi GM,Patel PS

    更新日期:2014-12-01 00:00:00

  • A polysaccharide from Grifola frondosa relieves insulin resistance of HepG2 cell by Akt-GSK-3 pathway.

    abstract::Grifola frondosa is an important fungal research resource. However, there was little report about hyperglycemic activity of Grifola frondosa polysaccharide on insulin resistance in vitro. In this study, the hypoglycemic activity of a polysaccharide obtained from Grifola frondosa (GFP) on HepG2 cell and hpyerglycemic m...

    journal_title:Glycoconjugate journal

    pub_type: 杂志文章

    doi:10.1007/s10719-014-9526-x

    authors: Ma X,Zhou F,Chen Y,Zhang Y,Hou L,Cao X,Wang C

    更新日期:2014-07-01 00:00:00

  • Early stage fetal neocortex exhibits a complex ganglioside profile as revealed by high resolution tandem mass spectrometry.

    abstract::In this study we report on the first mass spectrometric (MS) investigation of gangliosides and preliminary assessment of the expression and structure in normal fetal neocortex in early developmental stages: 14th (Neo14) and 16th (Neo16) gestational weeks. Ganglioside analysis was carried out using a hybrid quadrupole ...

    journal_title:Glycoconjugate journal

    pub_type: 杂志文章

    doi:10.1007/s10719-014-9517-y

    authors: Ghiulai RM,Sarbu M,Vukelić Ž,Ilie C,Zamfir AD

    更新日期:2014-04-01 00:00:00

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