abstract：:The prevalence of colorectal cancer (CRC) continues to increase. Treatment of CRC remains a significant clinical challenge, and effective therapies for advanced CRC are desperately needed. Increasing attention and ongoing research efforts have focused on krill oil that may provide health benefits to the human body. He...

journal_title：Lipids

authors： Jing W,Bi Y,Wang G,Zeng S,Han L,Yang H,Wang N,Zhao Y

更新日期：2020-09-15 00:00:00

abstract：:To better understand how docosahexaenoic acid (DHA) improves the effects of doxorubicin (DOX), we examined DHA ± DOX on changes in whole cell and lipid raft phospholipids (PL) of MDA-MB-231 and MCF-7 breast cancer cells. We sought to confirm whether the relative changes in PL DHA content of MDA-MB-231 cells could be e...

journal_title：Lipids

authors： Newell M,Patel D,Goruk S,Field CJ

更新日期：2020-09-01 00:00:00

abstract：:Vegetable oils are one of the main agricultural commodities. Demand has been increasing steadily over the last five decades and, with finite land available, it is vital that we increase productivity. My laboratory has focused on the regulation of plant lipid metabolism and, as part of this work, we identified diacylgl...

journal_title：Lipids

authors： Harwood JL

更新日期：2020-09-01 00:00:00

abstract：:In this study, to obtain further information on the structural diversity of non-methylene-interrupted (NMI) fatty acids (FA) in the gonads of the limpet Cellana toreuma, previously unreported minor NMI FA, fractionated by argentation thin-layer chromatography (TLC), in the ovaries were characterized by gas chromatogra...

journal_title：Lipids

authors： Kawashima H

更新日期：2020-05-01 00:00:00

abstract：:In the present study, the structural characteristics that impart antibacterial activity to C16 alkynoic fatty acids (aFA) were further investigated. The syntheses of hexadecynoic acids (HDA) containing triple bonds at C-3, C-6, C-8, C-9, C-10, and C-12 were carried out in four steps and with an overall yield of 34-78%...

journal_title：Lipids

authors： Sanabria-Ríos DJ,Morales-Guzmán C,Mooney J,Medina S,Pereles-De-León T,Rivera-Román A,Ocasio-Malavé C,Díaz D,Chorna N,Carballeira NM

更新日期：2020-03-01 00:00:00

abstract：:The growing prevalence of childhood obesity has become a serious health problem over the past few decades. Although the immune system is greatly affected by childhood obesity, whether obesity influences the T cell development in the thymus is poorly understood. In this study, we used a high-fat diet (HFD)-induced obes...

journal_title：Lipids

authors： Li H,Wetchapinant C,Zhang L,Wu K

更新日期：2020-01-01 00:00:00

abstract：:Specific inhibitors of diacylglycerol kinase (DGK) ζ can be promising anticancer medications via the activation of cancer immunity. Although the detection of cellular activities of target enzymes is essential for drug screening in addition to in vitro assays, it is difficult to detect the activity of DGKζ in cells. In...

journal_title：Lipids

authors： Honda S,Murakami C,Yamada H,Murakami Y,Ishizaki A,Sakane F

更新日期：2019-11-01 00:00:00

abstract：:The fatty acid (FA) profile of oysters generally reflects the dietary FA composition. Moreover, incorporation of FA into tissues is modulated by various metabolic factors, and final composition will depend upon the dietary sources, cumulative intake, and oysters' development stage. Thus, the aim of this study was to a...

journal_title：Lipids

authors： Rato A,Pereira LF,Joaquim S,Gomes R,Afonso C,Cardoso C,Machado J,Gonçalves JFM,Vaz-Pires P,Magnoni LJ,Matias AM,Matias D,Bandarra NM,Ozório ROA

更新日期：2019-09-01 00:00:00

abstract：:Exercise training not only improves the plasma lipid profile but also reduces risk of developing coronary heart disease. We investigate whether plasma lipids and high density lipoprotein (HDL) metabolism are affected by aerobic training and whether the high-density lipoprotein cholesterol (HDL-C) levels at baseline in...

journal_title：Lipids

authors： da Silva JL,Maranhão RC,Silva MSM,Dias RG,Freitas FR,Bolani W,Lemos Junior JR,Alves CR,Oliveira PA,Alves GB,Oliveira EM,Negrao CE,Krieger JE,Pereira AC,Silva GA,Souza JP,Vinagre CGC

更新日期：2019-06-01 00:00:00

abstract：:Four bacterial isolates, which produced polyunsaturated fatty acids (PUFA), were isolated from water samples of radioactive springs collected from Jáchymov spa. Jáchymov (Sankt Joachimsthal) is a city in northwestern Bohemia, where Marie and Pierre Curie isolated radium in 1898 from the mineral uraninite. To date, fou...

journal_title：Lipids

authors： Řezanka T,Gharwalová L,Nováková G,Kolouchová I,Uhlík O,Sigler K

更新日期：2019-02-01 00:00:00

abstract：:The aim of the present work was to study the effect of season on phospholipids and triacylglycerols (TAG) of mantle and tentacles of female and male wild Sepia officinalis. The identified phospholipids were phosphatidylethanolamine (PtdEtn), phosphatidylcholine (PtdCho), phosphatidylserine (PtdSer), and phosphatidylin...

journal_title：Lipids

authors： Tir M,El Cafsi I,Ammar RB,Mejri H,Tlili N,El Cafsi M

更新日期：2019-02-01 00:00:00

abstract：:Previous reports have suggested that cargo-free cationic nanoparticles (cNP) consisting of cationic monovalent lipids, such as 1,2-oleoyl-3-trimethylammonium-propane (DOTAP), induce reactive oxygen species (ROS) generation and toxicity in cells. In addition, cNP containing six lysine residues (6K) and cargo (6K-cNP) e...

journal_title：Lipids

authors： Bae CS,Ahn T

更新日期：2018-11-01 00:00:00

abstract：:Fatty acids are involved in the regulation of inflammatory responses in obesity. However, despite being the largest dietary fatty-acid class, effects of 18-carbon fatty acids with different degrees of saturation on inflammatory, metabolic, and thermogenic markers have not been well studied. Therefore, the objective of...

journal_title：Lipids

authors： Shin S,Ajuwon KM

更新日期：2018-09-01 00:00:00

abstract：:A method for the direct preparation of fatty-acid methyl esters (FAME) was simplified for fatty-acid analysis of a single fish larva using gas chromatography (GC). The method included the isolation of a larval trunk and drying in a glass vial, followed by saponification of all the contents without prior lipid extracti...

journal_title：Lipids

authors： Matsumoto Y,Ando Y,Hiraoka Y,Tawa A,Ohshimo S

更新日期：2018-09-01 00:00:00

abstract：:Plant diseases caused by Phytophthora species are serious threats to agriculture and the natural environment. Genome sequencing has revealed the lack of a gene for canonical phospholipase C (PLC), an enzyme that was hitherto thought to be ubiquitous in eukaryotes. PLC acts in the hydrolysis of phosphatidylinositol 4,5...

journal_title：Lipids

authors： Howard JM,Beech PL,Callahan DL

更新日期：2018-08-01 00:00:00

abstract：:Recently, a new assay method that can quantify the singlet oxygen-absorption capacity (SOAC) of antioxidants (AO) and food extracts in homogeneous organic solvents has been proposed. In the present study, second-order rate constants (kQ ) for the reaction of singlet oxygen (1 O2 ) with vitamin E homologs (α-, β-, γ-, ...

journal_title：Lipids

authors： Mukai K,Ishikawa E,Ouchi A,Nagaoka SI,Abe K,Suzuki T,Izumisawa K

更新日期：2018-06-01 00:00:00

abstract：:Cis-9-conjugated, trans-11-conjugated linoleic acid (CLA) is known for its positive activities on human health. The synthesis of cis-9, trans-11 CLA in mammary glands is generally thought to be catalyzed by stearoyl-CoA desaturase 1 (SCD1), but this has not been rigorously established. In this study, we hypothesized t...

journal_title：Lipids

authors： Wang T,Lee H,Zhen Y

更新日期：2018-06-01 00:00:00

abstract：:Liver fatty-acid-binding protein (FABP1, L-FABP) is the major cytosolic binding/chaperone protein for both precursor arachidonic acid (ARA) and the endocannabinoid (EC) products N-arachidonoylethanolamine (AEA) and 2-arachidonoylglycerol (2-AG). Although FABP1 regulates hepatic uptake and metabolism of ARA, almost not...

journal_title：Lipids

authors： McIntosh AL,Huang H,Landrock D,Martin GG,Li S,Kier AB,Schroeder F

更新日期：2018-06-01 00:00:00

abstract：:Saturated fatty acids are the most abundant fatty acids in the brain, however, there has been some debate regarding the ability of intact dietary saturated fatty acids to be incorporated into the brain. In the present study, we use compound specific isotope analysis to measure the natural abundance carbon isotopic sig...

journal_title：Lipids

authors： Lacombe RJS,Giuliano V,Chouinard-Watkins R,Bazinet RP

更新日期：2018-05-01 00:00:00

abstract：:Freshwater bryozoan Pectinatella magnifica was collected from a sand pit (South Bohemia). The total lipids after extraction from lyophilized bryozoans were analyzed using high-performance liquid chromatography/high-resolution negative tandem electrospray mass spectrometry. A total of 19 lipid classes were identified, ...

journal_title：Lipids

authors： Řezanka T,Vítová M,Lukavský J,Sigler K

更新日期：2018-04-01 00:00:00

abstract：:We evaluated whether CETP and LCAT gene polymorphisms are statistically associated with the high-density lipoprotein (HDL) size distribution, the cholesterol level of HDL subclasses, and the acute coronary syndrome (ACS) susceptibility. Two CETP gene polymorphisms (rs4783961 and rs708272) and one LCAT polymorphism (rs...

journal_title：Lipids

authors： Vargas-Alarcon G,Perez-Mendez O,Herrera-Maya G,Garcia-Sanchez C,Martinez-Rios MA,Peña-Duque MA,Posadas-Sanchez R,Posadas-Romero C,Escobedo G,Fragoso JM

更新日期：2018-02-01 00:00:00

abstract：:Left ventricular (LV) remodeling after myocardial infarction constitutes the structural basis for ventricular dysfunction and heart failure. The characterization underlying the expression of lipoprotein receptors in cardiac dysfunction is scarcely explored. The aim of this study was to analyze the status of lipoprotei...

journal_title：Lipids

authors： de Lima AD,Guido MC,Tavares ER,Carvalho PO,Marques AF,de Melo MDT,Salemi VMC,Kalil-Filho R,Maranhão RC

更新日期：2018-02-01 00:00:00

abstract：:N6 -methyladenosine (m6 A) regulates gene expression and affects cellular metabolism. In this study, we checked whether the regulation of lipid metabolism by curcumin is associated with m6 A RNA methylation. We investigated the effects of dietary curcumin supplementation on lipopolysaccharide (LPS)-induced liver injur...

journal_title：Lipids

authors： Lu N,Li X,Yu J,Li Y,Wang C,Zhang L,Wang T,Zhong X

更新日期：2018-01-01 00:00:00

abstract：:Docosahexaenoic acid (DHA), a prominent long-chain fatty acid of the omega-3 family, is present at high amount in brain tissues, especially in membrane phospholipids. This polyunsaturated fatty acid is the precursor of various oxygenated lipid mediators involved in diverse physiological and pathophysiological processe...

journal_title：Lipids

authors： Jouvène C,Fourmaux B,Géloën A,Balas L,Durand T,Lagarde M,Létisse M,Guichardant M

更新日期：2018-01-01 00:00:00

abstract：:A fast and efficient shotgun lipidomics strategy was applied to analyze phospholipids (PL) in the oyster Crassostrea plicatula, including 29 species of phosphatidylcholine (PtdCho), 23 species of phosphatidylethanolamine (PtdEtn), 11 species of phosphatidylserine (PtdSer), 6 species of phosphatidylinositol (PtdIns), a...

journal_title：Lipids

authors： Chen Q,Wang X,Cong P,Liu Y,Wang Y,Xu J,Xue C

更新日期：2017-12-01 00:00:00

abstract：:Dietary fatty acids have different effects on fat deposition in pigs. To clarify the underlying mechanisms of this difference, we compared the metabolism of palmitic (PAM, saturated), oleic (OLA, monounsaturated) and linoleic acid (LNA, polyunsaturated) in porcine adipocytes treated with 100 μM PAM, OLA or LNA. We obs...

journal_title：Lipids

authors： Yu C,Xi L,Chen J,Jiang Q,Yi H,Wang Y,Wang X

更新日期：2017-11-01 00:00:00

abstract：:Previous studies show that long term variations in dietary fat consumption impact circulating fatty acid ethanolamide (FAE) concentrations, however, few studies have investigated short term effects of dietary fat feeding on FAE levels. The trial's objective was to explore the effect of acute feeding of varying amounts...

journal_title：Lipids

authors： Olatinsu AO,Sihag J,Jones PJH

更新日期：2017-11-01 00:00:00

abstract：:The tail gland of the red fox (Vulpes vulpes) secretes lipids containing volatile terpenes used in social communication. We have analysed lipids extracted from fur of the tail gland, body (flanks) and muzzle of foxes. GC-MS showed a novel group of iso-valerate and tiglate monoesters of alkane-1,2-diols (C18:0-22:0). T...

journal_title：Lipids

authors： McLean S,Davies NW,Nichols DS

更新日期：2017-07-01 00:00:00

abstract：:The naturally occurring (6Z)-(±)-2-methoxy-6-hexadecenoic acid (1) and (6Z)-(±)-2-methoxy-6-octadecenoic acid (2) were synthesized in 7-8 steps with 38 and 13% overall yields, respectively, by using an acetylide coupling approach, which made it possible to obtain a 100% cis-stereochemistry for the double bonds. In a s...

journal_title：Lipids

authors： Carballeira NM,Montano N,Morales C,Mooney J,Torres X,Díaz D,Sanabria-Rios DJ

更新日期：2017-06-01 00:00:00

abstract：:The gut microbiota is proposed as a "metabolic organ" involved in energy utilization and is associated with obesity. Dietary intervention is one of the approaches for obesity management. Changes in dietary components have significant impacts on host metabolism and gut microbiota. In the present study, we examined the ...

journal_title：Lipids

authors： Shang Y,Khafipour E,Derakhshani H,Sarna LK,Woo CW,Siow YL,O K

更新日期：2017-06-01 00:00:00

abstract：:Ceramide 2-aminoethylphosphonate (CAEP), a sphingophosphonolipid containing a carbon-phosphorus bond, is frequently found in marine organisms and has a unique triene type of sphingoid base in its structure. CAEP has not been evaluated as a food ingredient, although it is generally contained in Mollusca organisms such ...

journal_title：Lipids

authors： Tomonaga N,Manabe Y,Sugawara T

更新日期：2017-04-01 00:00:00

abstract：:Barth syndrome (BTHS) is an X-linked genetic disease resulting in loss of cardiolipin (Ptd2Gro). Patients may be predisposed to hypoglycemia and exhibit increases in whole-body glucose disposal rates and a higher fat mass percentage. We examined the reasons for this in BTHS lymphoblasts. BTHS lymphoblasts exhibited a ...

journal_title：Lipids

authors： Mejia EM,Zinko JC,Hauff KD,Xu FY,Ravandi A,Hatch GM

更新日期：2017-02-01 00:00:00

abstract：:During ruminal biohydrogenation of α-linolenic acid, a non-conjugated non-methylene interrupted dienoic acid is formed containing a t10 double bond, namely t10,c15-18:2. The present study was designed to examine whether t10,c15-18:2 would exert similar anti-adipogenic effects compared to t10,c12-18:2 in 3T3-L1 adipocy...

journal_title：Lipids

authors： Vahmani P,Meadus WJ,Rolland DC,Duff P,Dugan ME

更新日期：2016-11-01 00:00:00

abstract：:Omega-3 (n-3) long-chain polyunsaturated fatty acids (LC-PUFA) are essential components of the diet of all vertebrates. The major dietary source of n-3 LC-PUFA for humans has been fish and seafood but, paradoxically, farmed fish are also reliant on marine fisheries for fish meal and fish oil (FO), traditionally major ...

journal_title：Lipids

authors： Betancor MB,Sprague M,Montero D,Usher S,Sayanova O,Campbell PJ,Napier JA,Caballero MJ,Izquierdo M,Tocher DR

更新日期：2016-10-01 00:00:00

abstract：:Flaxseed oil is an alpha linolenic acid source important in the growth and body development stage; furthermore, this acid acts on adipose tissue and bone health. The aim of this study was to evaluate body composition, fatty acid composition, hormone profile, retroperitoneal adipocyte area and femur structure of pups a...

journal_title：Lipids

authors： Pereira AD,Ribeiro DC,de Santana FC,de Sousa Dos Santos A,Mancini-Filho J,do Nascimento-Saba CC,Velarde LG,da Costa CA,Boaventura GT

更新日期：2016-08-01 00:00:00

abstract：:The objective of this study was to establish the impact of caloric restriction on high fat diet-induced alterations on regulators of skeletal muscle growth. We hypothesized that caloric restriction would reverse the negative effects of high fat diet-induced obesity on REDD1 and mTOR-related signaling. Following an ini...

journal_title：Lipids

authors： Dungan CM,Li J,Williamson DL

更新日期：2016-08-01 00:00:00

abstract：:We recently reported the presence of various cyclopropane fatty acids-among them, cyclopropaneoctanoic acid 2-hexyl-in the adipose tissue of obese women. The aim of this study was to verify whether the presence of cyclopropaneoctanoic acid 2-hexyl in human serum was associated with obesity or chronic kidney disease (b...

journal_title：Lipids

authors： Mika A,Stepnowski P,Chmielewski M,Malgorzewicz S,Kaska L,Proczko M,Ratnicki-Sklucki K,Sledzinski M,Sledzinski T

更新日期：2016-07-01 00:00:00

abstract：:Hempseed products represent potential alternative feed ingredients for poultry. However, their usage is not currently approved due to a lack of data to support their safety and efficacy. In this regard, the current study was conducted to assess the impact of dietary concentration of hempseed (HS) products and duration...

journal_title：Lipids

authors： Neijat M,Suh M,Neufeld J,House JD

更新日期：2016-05-01 00:00:00

abstract：:Dysregulation of adipokines is a hallmark of obesity. Polyunsaturated fatty acids in fish oil may exert anti-inflammatory effects on adipose tissue mitigating the dysregulation of adipokines thereby preventing obesity. This study investigated the effects of high-fat diets containing different amounts of n3 polyunsatur...

journal_title：Lipids

authors： Sundaram S,Bukowski MR,Lie WR,Picklo MJ,Yan L

更新日期：2016-05-01 00:00:00

abstract：:The aim of this study was to develop a simple method for simultaneous determination of selected cis/cis PUFA-LNA (18:2), ALA (18:3), GLA (18:3), EPA (20:5), and DHA (22:6) by silver ion high-performance liquid chromatography coupled to a diode array detector (Ag-HPLC-DAD). The separation was performed on three Luna SC...

journal_title：Lipids

authors： Czajkowska-Mysłek A,Siekierko U,Gajewska M

更新日期：2016-04-01 00:00:00