Ultra-Performance Liquid Chromatography-Mass Spectrometry Analysis of Free and Esterified Oxygenated Derivatives from Docosahexaenoic Acid in Rat Brain.

abstract：:The contents and compositions of the 1-O-alk-1'-enyl-2-acyl, 1-O-alkyl-2-acyl, and 1,2-diacyl glycerophospholipids in the muscle and viscera of the ascidian Halocynthia roretzi, and of the gonad of the sea urchin Strongylocentrotus intermedius, which are eaten to some extent in Alaska and in Asia, were analyzed by gas...

journal_title：Lipids

authors： Jeong BY,Ohshima T,Koizumi C

更新日期：1996-01-01 00:00:00

abstract：:Membrane phospholipid (PL) composition has been shown to affect cellular function by altering membrane physical structure. The sarcolemma plasma membrane (SLpm) is integral to skeletal muscle function and health. Previous studies assessing SLpm PL composition have demonstrated contamination from transverse (t)-tubule,...

journal_title：Lipids

authors： Fajardo VA,McMeekin L,Basic A,Lamb GD,Murphy RM,LeBlanc PJ

更新日期：2013-04-01 00:00:00

abstract：:Male Sprague-Dawley rats were fed diets for 1 or 16 weeks, containing 20% by weight vegetable oils differing widely in their oleic, linoleic and linolenic acid content. No significant changes were observed in the level of the cardiac lipid classes. The fatty acid composition of the 2 major phospholipids, phosphatidylc...

journal_title：Lipids

authors： Kramer JK

更新日期：1980-09-01 00:00:00

abstract：:By using reverse transcription-polymerase chain reaction technology (RT-PCR) and Northern blot analysis, the tissue-specific mRNA expression patterns of seven mouse lipoxygenases (LOX)--including 5S-, 8S-, three isoforms of 12S-, 12R-LOX, and a LOX of an as-of-yet unknown specificity, epidermis-type LOX-3 (e-LOX-3)--w...

journal_title：Lipids

authors： Heidt M,Fürstenberger G,Vogel S,Marks F,Krieg P

更新日期：2000-07-01 00:00:00

abstract：:Recently, a new assay method that can quantify the singlet oxygen-absorption capacity (SOAC) of antioxidants (AO) and food extracts in homogeneous organic solvents has been proposed. In the present study, second-order rate constants (kQ ) for the reaction of singlet oxygen (1 O2 ) with vitamin E homologs (α-, β-, γ-, ...

journal_title：Lipids

authors： Mukai K,Ishikawa E,Ouchi A,Nagaoka SI,Abe K,Suzuki T,Izumisawa K

更新日期：2018-06-01 00:00:00

abstract：:Fatty acid composition of plasma phospholipids (PL), triglycerides (TG), and sterol esters (STE) was determined by high-resolution capillary gas-liquid chromatography in 22 obese children (age: 13.7 +/- 1.4 y, body weight relative to normal weight for height: 170 +/- 24%, mean +/- SD) and compared with data obtained i...

journal_title：Lipids

authors： Decsi T,Molnár D,Koletzko B

更新日期：1996-03-01 00:00:00

abstract：:Four bacterial isolates, which produced polyunsaturated fatty acids (PUFA), were isolated from water samples of radioactive springs collected from Jáchymov spa. Jáchymov (Sankt Joachimsthal) is a city in northwestern Bohemia, where Marie and Pierre Curie isolated radium in 1898 from the mineral uraninite. To date, fou...

journal_title：Lipids

authors： Řezanka T,Gharwalová L,Nováková G,Kolouchová I,Uhlík O,Sigler K

更新日期：2019-02-01 00:00:00

abstract：:(8R)-Hydroperoxy-(9Z,12Z)-octadecadienoic acid (8-HPODE) is formed by aspergilli as an intermediate in biosynthesis of oxylipins with effects on sporulation. 8-HPODE is transformed by separate diol synthases to (5S,8R)-dihydroxy- and (8R,11S)-dihydroxy-(9Z,12Z)-octadecadienoic acids (5,8- and 8,11-DiHODE). The former ...

journal_title：Lipids

authors： Jernerén F,Oliw EH

更新日期：2012-07-01 00:00:00

abstract：:Iron and ascorbic acid appear to be the normal catalytic components responsible for the lipid peroxidation reaction in aerobically incubated rat tissue homogenates. The amounts of each present in the catalytically-active fractions of rat liver, brain, testis, and kidney are appropriate to explain the lipid peroxidatio...

journal_title：Lipids

authors： Barber AA

更新日期：1966-03-01 00:00:00

abstract：:The effect of SM-10661, a selective antagonist of platelet-activating factor (PAF), on passive anaphylactic bronchoconstriction was examined in guinea pigs. A challenge of ovalbumin to passively sensitized guinea pigs induced bronchoconstriction, which peaked at 4 min. When SM-10661 was administered intravenously 2 mi...

journal_title：Lipids

authors： Uchida M,Imanishi N,Sugasawa T,Morooka S

更新日期：1991-12-01 00:00:00

abstract：:Dietary lipids, in particular unsaturated fat, promote the development of many experimental tumors. However, no mechanisms to fully explain these effects have been elucidated. Recent reports, which we summarize here, suggest a role for gap junction-mediated intercellular communication in the process of tumor promotion...

journal_title：Lipids

authors： Aylsworth CF,Welsch CW,Kabara JJ,Trosko JE

更新日期：1987-06-01 00:00:00

abstract：:CLA has a range of biological properties, including effects on lipid metabolism and body composition in experimental animals. The prevalent isomer of CLA found in the human diet is 9c,11 t-CLA, and it is predominantly found in products containing fat from ruminant animals. This study investigated the effect of dietary...

journal_title：Lipids

authors： Hayman A,MacGibbon A,Pack RJ,Rutherfurd K,Green JH

更新日期：2002-07-01 00:00:00

abstract：:The present study was performed to investigate the effect of dietary conjugated linoleic acid (CLA) on the growth performance, immune parameters and disease resistance to Aeromonas hydrophila of juvenile Jian carp. A total of 900 juvenile Jian carp (10.71 +/- 0.02 g) were randomly allocated into six groups of each thr...

journal_title：Lipids

authors： Jiang J,Zhao MJ,Lin F,Yang L,Zhou XQ

更新日期：2010-06-01 00:00:00

abstract：:The effect of apo very low density lipoprotein (apo VLDL) and apoprotein C-II on the phospholipase A1 activity associated with lipoprotein lipase (E.C.3.1.1.3) was studied using purified bovine milk lipoprotein lipase. The enzyme degraded 14C phosphatidylcholine (PC) to 14C 2-acyl lysophosphatidylcholine at a rate of ...

journal_title：Lipids

authors： Stocks J,Galton DJ

更新日期：1980-03-01 00:00:00

abstract：:We have previously reported that the relative content of 18:3 omega 3 in adipose triglyceride (TG) of women was reduced following major weight loss while on a very low calorie diet (VLCD). In an attempt to prevent this loss of 18:3 omega 3 reserves, we have tested two VLCD supplemented with varying amounts of 18:3 ome...

journal_title：Lipids

authors： Tang AB,Nishimura KY,Phinney SD

更新日期：1993-11-01 00:00:00

abstract：:A simple method is described for the preparation of [6,7,7(-2)H3] sterols and steroids. The synthesis starts with a Δ(5)-sterol or steroid and involves preparation of the 6-oxo-3α,5α-cyclosteroid, base exchange in the presence of deuterium oxide to introduce two deuteriums at the C-7 position and sodium borodeuteride ...

journal_title：Lipids

authors： Goad LJ,Breen MA,Rendell NB,Rose ME,Duncan JN,Wade AP

更新日期：1982-12-01 00:00:00

abstract：:HMG-CoA reductase (HMGCR) is an enzyme involved in cholesterol synthesis. To investigate the contribution of the HMGCR gene to lipids and lipoprotein subfractions in different ethnicities, we performed an association study in the Multi-Ethnic Study of Atherosclerosis (MESA). In total, 2,444 MESA subjects [597 African-...

journal_title：Lipids

authors： Chen YC,Chen YD,Li X,Post W,Herrington D,Polak JF,Rotter JI,Taylor KD

更新日期：2009-08-01 00:00:00

abstract：:Jasmonic acid (JA) is synthesized from linolenic acid (18:3n-3) by sequential action of 13-lipoxygenase, allene oxide synthase (AOS), and allene oxide cyclase. The fungus Lasiodiplodia theobromae can produce large amounts of JA and was recently reported to form the JA precursor 12-oxophytodienoic acid. The objective o...

journal_title：Lipids

authors： Jernerén F,Eng F,Hamberg M,Oliw EH

更新日期：2012-01-01 00:00:00

abstract：:The effects of different dietary fats on ovine adipose tissue metabolism have been investigated. Six-month old sheep were fed for 6 weeks a control diet or diets supplemented with either tallow or a mixture of sunflower seed oil and soybean oil, treated to protect the fats from hydrolysis and hydrogenation in the rume...

journal_title：Lipids

authors： Vernon RG

更新日期：1976-09-01 00:00:00

abstract：:Oxidized low density lipoprotein (Ox-LDL) is a well-established risk factor in atherosclerosis and lysophosphatidylcholine (LysoPtdCho) is considered to be one of the major atherogenic component of Ox-LDL. The purpose of this work was to investigate the effects of two membrane n-3 long chain polyunsaturated fatty acid...

journal_title：Lipids

authors： Tardivel S,Gousset-Dupont A,Robert V,Pourci ML,Grynberg A,Lacour B

更新日期：2009-03-01 00:00:00

abstract：:Normal phase high performance liquid chromatography methods are described for the separation of neutral lipid, fatty acid and five phospholipid classes using spectrophotometric detection at 206 nm. Separations were accomplished in less than 10 min for each lipid class. A mobile phase consisting of hexane/methyltertiar...

journal_title：Lipids

authors： Hamilton JG,Comai K

更新日期：1988-12-01 00:00:00

abstract：:The importance of n-6 and n-3 polyunsaturated fatty acids (PUFA) in neonatal development, particularly with respect to the developing brain and retina, is well known. This review combines recent information from basic science and clinical studies to highlight recent advances in knowledge on PUFA metabolism and areas w...

journal_title：Lipids

authors： Innis SM,Sprecher H,Hachey D,Edmond J,Anderson RE

更新日期：1999-02-01 00:00:00

abstract：:We examined the effect of dietary alpha-linolenic acid (ALA) on the indices of lipid and coagulation status and on the fatty acid composition of serum and peripheral blood mononuclear cell (PBMNC) lipids in ten healthy men (age 21-37 yr) who consumed all their meals at the Western Human Nutrition Research Center for 1...

journal_title：Lipids

authors： Kelley DS,Nelson GJ,Love JE,Branch LB,Taylor PC,Schmidt PC,Mackey BE,Iacono JM

更新日期：1993-06-01 00:00:00

abstract：:Synthetic activators of peroxisome proliferator-activated receptors (PPAR)-alpha and -gamma are capable of reducing macrophage foam cell cholesterol accumulation through the activation of genes involved in cholesterol homeostasis. Since conjugated linoleic acids (CLA) were also demonstrated to activate PPARalpha and P...

journal_title：Lipids

authors： Ringseis R,Wen G,Saal D,Eder K

更新日期：2008-10-01 00:00:00

abstract：:Primary cultured hepatocytes from normal mice and mice with Sarcoma 180 were characterized. The viability of freshly isolated hepatocytes from both sources was over 90% and the cells had a relatively stable population of DNA for a minimum of three days. After incubation with (3H)leucine, the syntheses and secretions o...

journal_title：Lipids

authors： Masuno H,Okuda H

更新日期：1985-07-01 00:00:00

abstract：:A simple and sensitive method to analyze mixtures of desmosterol, 7-dehydrocholesterol and cholesterol is described. The method involves the oxidative conversion of the sterols with cholesterol oxidase, followed by high performance liquid chromatographic (HPLC) analysis. A C18 reversed phase column (3 microns, 75 X 4....

journal_title：Lipids

authors： Goh EH,Colles SM,Otte KD

更新日期：1989-07-01 00:00:00

abstract：:The phospholipid composition of gill tissue from thermally acclimated rainbow trout, Salmo gairdneri, was determined by Iatroscan analysis following an initial development of the chromarods in a non-polar solvent to remove neutral lipids. Standard curves for all phospholipids, although linear through most of the conce...

journal_title：Lipids

authors： Hazel JR

更新日期：1985-08-01 00:00:00

abstract：:Phospholipids are integral constituents of the milk fat globule membranes and they play a central role in infants' immune and inflammatory responses. A methodology employing liquid chromatography coupled with evaporative light scattering detector has been optimized and validated to quantify the major phospholipids cla...

journal_title：Lipids

authors： Giuffrida F,Cruz-Hernandez C,Flück B,Tavazzi I,Thakkar SK,Destaillats F,Braun M

更新日期：2013-10-01 00:00:00

abstract：:The eicosapentaenoic acid (EPA) synthesis gene cluster from an EPA-producing bacterium, Shewanella sp. SCRC-2738, was cloned into a broad-host range vector, pJRD215, and then introduced into a marine cyanobacterium, Synechococcus sp. NKBG15041c, by conjugation. The transconjugant cyanobacteria produced 3.7 +/- 0.2% (2...

journal_title：Lipids

authors： Yu R,Yamada A,Watanabe K,Yazawa K,Takeyama H,Matsunaga T,Kurane R

更新日期：2000-10-01 00:00:00

abstract：:The compositions of the fatty acids in the 1, 2 and 3 positions of the principal glycerolipids and their various stereoisomers were determined. Fatty acids in the 1 and 3 positions of triglycerides were similar in composition and less unsaturated than those in the 2 position. Fatty acids in the 1,2-, 1,3- and 2,3-digl...

journal_title：Lipids

authors： Arunga RO,Morrison WR

更新日期：1971-10-01 00:00:00