Abstract:
:Primary cultured hepatocytes from normal mice and mice with Sarcoma 180 were characterized. The viability of freshly isolated hepatocytes from both sources was over 90% and the cells had a relatively stable population of DNA for a minimum of three days. After incubation with (3H)leucine, the syntheses and secretions of (3H)labeled trichloracetic acid-insoluble materials by hepatocytes from both normal and tumor-bearing mice increased similarly. However, the alkaline triglyceride lipase activity of a homogenate of freshly isolated hepatocytes from tumor-bearing mice was one-third that of cells from normal mice. The activity of hepatocytes from tumor-bearing mice increased less during culture than did the activity of cells isolated from normal mice.
journal_name
Lipidsjournal_title
Lipidsauthors
Masuno H,Okuda Hdoi
10.1007/BF02534229subject
Has Abstractpub_date
1985-07-01 00:00:00pages
399-403issue
7eissn
0024-4201issn
1558-9307journal_volume
20pub_type
杂志文章相关文献
LIPIDS文献大全abstract::Fatty acid compositions of polar lipids and triacylglycerols isolated from eggs of the sea urchin, Arbacia punctulata, were examined before and 15 min after insemination. The main fatty acids present in polar lipids and triacylglycerols were palmitate, palmitoleate, eicosaenoate, arachidonate and eicosapentaenoate, wh...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/BF02533484
更新日期:1978-11-01 00:00:00
abstract::Feline omental lipid extracts, previously reported to be angiogenic in the cornea of rabbits, were fractionated and the major lipid components characterized. Approximately 97% of the chloroform/methanol extract consisted of triglycerides containing primarily 16:0, 18:0, 18:1 and 18:2 fatty acids. Trace quantities of f...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/BF02533984
更新日期:1987-04-01 00:00:00
abstract::Iron and ascorbic acid appear to be the normal catalytic components responsible for the lipid peroxidation reaction in aerobically incubated rat tissue homogenates. The amounts of each present in the catalytically-active fractions of rat liver, brain, testis, and kidney are appropriate to explain the lipid peroxidatio...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/BF02533008
更新日期:1966-03-01 00:00:00
abstract::An analysis of the lipids in swine influenza vaccines was performed, comparing six different lots of swine influenza, other influenza and noninfluenza vaccines. Cholesterol content and phospholipid content varied greatly, but there were no major differences between the types of vaccines. Appreciable amounts of phospha...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/BF02535698
更新日期:1986-05-01 00:00:00
abstract::The effect of SM-10661, a selective antagonist of platelet-activating factor (PAF), on passive anaphylactic bronchoconstriction was examined in guinea pigs. A challenge of ovalbumin to passively sensitized guinea pigs induced bronchoconstriction, which peaked at 4 min. When SM-10661 was administered intravenously 2 mi...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/BF02536553
更新日期:1991-12-01 00:00:00
abstract::Plasma lipidomic studies using high performance liquid chromatography and mass spectroscopy offer detailed insights into metabolic processes. Taking the example of the most abundant plasma lipid class (phosphatidylcholines) we used the rich phenotypic and lipidomic data from the ongoing San Antonio Family Heart Study ...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/s11745-013-3781-7
更新日期:2013-05-01 00:00:00
abstract::Several water soluble and organic solvent soluble fluorescent peaks were observed in extracts of uteri from vitamin E deficient or supplemented rats following Sephadex column chromatography and spectrophotofluorometric analysis. Levels of one of the organic and two of the water soluble fluorescent peaks were found to ...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/BF02534725
更新日期:1984-12-01 00:00:00
abstract::It has been shown that different lysophosphatidylcholines (LPC) possess relaxing properties in vascular strips. We report on the effect of intraatrial injection of LPC micelles into white New Zealand rabbits. Changes in renal and coronary flow were determined by radioactive microspheres. Coronary blood flow increased ...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/BF02543975
更新日期:1991-03-01 00:00:00
abstract::Although hypocholesterolemia is a reported finding in sickle cell disease (SCD), low-density lipoprotein (LDL)/high-density lipoprotein (HDL) subfractions and HDL-associated enzymes have not been determined in SCD patients. Blood was collected from 38 hemoglobin (Hb)A volunteers and 45 homozygous HbSS patients who had...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/s11745-013-3849-4
更新日期:2013-12-01 00:00:00
abstract::By means of cellulose acetate electrophoresis and measurement of radio-activity, lipoproteins (d less than or equal to 1,006) of lymph collected from rats fed a diet containing fats added to labeled fatty acids for 20-24 hr, have been separated into two kinds differing in their size. Fats with different saturated and ...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/BF02535449
更新日期:1977-06-01 00:00:00
abstract::The synthesis of alkyl chain-substituted thiazanones from oxo fatty esters and a long chain aldehyde is reported. Four oxo compounds-methyl 10-oxoundecanoate, methyl 9-oxooctadecanoate, methyl 9,10-dioxooctadecanoate and octadecanal-were allowed to react with β-mercaptopropionic acid in the presence of ammonium carbon...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/BF02537284
更新日期:1987-08-01 00:00:00
abstract::Biosynthesis of peripheral nerve cholesterol was investigated by the in vivo and in vitro incorporation of [1-14C]-acetate into sciatic endoneurium of normal rats during development, degeneration and regeneration. Labeled sterols were rapidly formed (less than 10 min) within the endoneurial portion of sciatic nerve af...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/BF02536205
更新日期:1988-09-01 00:00:00
abstract::Chlorpromazine (CPZ), a major tranquilizer, was found to be a potent inhibitor of lecithin:cholesterol acyltransferase (LCAT, EC 2.3.1.43) in the plasma of normal man, rat, rabbit and dog in vitro. The inhibitory effect of CPZ reached 35-50% at 0.5 mM depending on species; dog plasma LCAT appeared to be somewhat more ...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/BF02535035
更新日期:1981-11-01 00:00:00
abstract::The activity of lysosomal acid cholesteryl ester hydrolase (acid CEH, EC 3.1.1.13) in rat liver was determined at 3, 5, 7, 10 and 20 wk following birth. The levels of acid CEH activity showed a marked decrease as rats grew older, whereas those of other lysosomal marker enzymes, such as acid phosphatase, beta-glucuroni...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/BF02533950
更新日期:1987-09-01 00:00:00
abstract::To better understand how docosahexaenoic acid (DHA) improves the effects of doxorubicin (DOX), we examined DHA ± DOX on changes in whole cell and lipid raft phospholipids (PL) of MDA-MB-231 and MCF-7 breast cancer cells. We sought to confirm whether the relative changes in PL DHA content of MDA-MB-231 cells could be e...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1002/lipd.12252
更新日期:2020-09-01 00:00:00
abstract::The purpose of this study was to assess changes in the degree of fatty acid unsaturation in rat liver after partial hepatectomy. This is the first study in which liver fatty acid unsaturation has been analyzed over a long period of regeneration until day 28 after operation. The relationship between changes in unsatura...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/s11745-000-543-9
更新日期:2000-04-01 00:00:00
abstract::Diets that contain high levels of n-3 fatty acids from fish oil have been shown to significantly effect macrophage cytolytic capacity, tumor necrosis factor alpha production and eicosanoid production. The present study was undertaken to determine whether n-3 fatty acids from vegetable origin [linseed oil (LIN)] would ...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/BF02536100
更新日期:1994-09-01 00:00:00
abstract::The conversion of labeled palmitic, linoleic, arachidonic and docosahexaenoic acids to their respective acyl CoA's was studied in homogenates and microsomes of rat tissues. The highest activity, both in homogenates and microsomes, was seen in liver and heart. There was moderate activity in retina, brain, lung, kidney ...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/BF02534740
更新日期:1984-12-01 00:00:00
abstract::A group of Angus beef cattle was removed from temperate pastures and fed a very low beta-carotene cereal-based ration in a feedlot for over 300 d. Half the group was supplemented weekly with retinyl palmitate (at the rate of 60,000 IU vitamin A/100 live weight (LW)/day), sufficient to offset clinical vitamin A deficie...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/s11745-006-5107-5
更新日期:2006-04-01 00:00:00
abstract::Cholesteryl esterase activities were determined in homogenates of rat heart (ventricles), isolated, calcium-tolerant, cardiac myocytes and aortic tissue and were compared with acid and neutral triglyceride lipase activities in these fractions. Using cholesteryl oleate/phosphatidylcholine/taurocholate emulsions and dig...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/BF02534862
更新日期:1987-02-01 00:00:00
abstract::Since it was first suggested that high dietary fat is a risk factor in colon cancer, there have been several studies to test this hypothesis. Epidemiologic studies suggested a positive association between dietary fat and colon cancer. Laboratory animal model studies demonstrated that not only the amount of fat, but al...
journal_title:Lipids
pub_type: 杂志文章,评审
doi:10.1007/BF02535855
更新日期:1992-10-01 00:00:00
abstract::Tetramethylammonium hydroxide has been used in the extraction and pyrolysis methylation of the carboxylic acids produced by periodate-permanganate oxidation of monounsaturated fatty acid methyl esters. This modification of the von Rudloff procedure allows rapid determination of double-bond positions and analysis of mi...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/BF02530977
更新日期:1968-01-01 00:00:00
abstract::Binding antibodies to surface membranes stimulated incorporation of fatty acids (FA) into phospholipids of L cells. Antibodies stimulated at least a 3.4-fold greater incorporation of arachidonic acid into phosphatidylinositol than into any other class of phospholipid when compared on a molar basis (p less than 0.003)....
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/BF02534451
更新日期:1984-04-01 00:00:00
abstract::The minimum requirement of linoleic acid to prevent effects of dietary C18 trans fatty acids on eicosanoid biosynthesis in rats was assessed. In a first experiment, six groups of animals were fed diets with a high content of trans fatty acids [20% of energy (en%)], and increasing amounts of linoleic acid (0.4 to 7.1 e...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/BF02535138
更新日期:1989-06-01 00:00:00
abstract::The monoazaaromatics, pyridine (1), hexyl nicotinate (2), and quinoline (3) and diazaaromatics, pyrimidine (4) and purine (5), readily act as photo-initiators for the peroxidation of methyl linoleate in 0.50 M SDS at 37 degrees C giving free radical chain oxidations of linoleate. Quantitative kinetic runs on the order...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/s11745-997-0030-3
更新日期:1997-03-01 00:00:00
abstract::Tris(N,N-dimethyl)amide of phosphorous acid activated by addition of iodine at an optimal molar ratio of 1.05:0.05 was used as a phosphorylating reagent to synthesize cholecalciferyl-3-O-(1-2-isopropylidene-rac-glycero-3-O-)-thiophos phate and cholecalciferyl-3-O-(1,2-dipalmitoyl-rac-glycero-3-O-)thiophosphat e of met...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/BF02536388
更新日期:1992-06-01 00:00:00
abstract::The oils from sclerotia or from suitable mycelial cultures ofClaviceps purpurea (ergot) contain up to 44% of ricinoleic acid but no free hydroxyl groups. This is due to the presence of, besides normal triglycerides, tetra-acid, penta-acid and hexa-acid triglycerides. These contain respectively one, two and three ricin...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/BF02531871
更新日期:1966-05-01 00:00:00
abstract::A recent study on the metabolism of 1-14C-alpha-linolenic acid in the guinea pig revealed that the fur had the highest specific activity of all tissues examined, 48 h after dosing. The present study investigated the pattern of tissue lipid labeling following an oral dose of 1-14C-linoleic acid after the animals had be...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/s11745-001-0715-7
更新日期:2001-03-01 00:00:00
abstract::Five groups of salmon, of initial mean weight 127 +/- 3 g, were fed increasing levels of dietary linseed oil (LO) in a regression design. The control diet contained capelin oil (FO) only, and the same oil was blended with LO to provide the experimental diets. After an initial period of 40 wk, all groups were switched ...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/s11745-004-1223-5
更新日期:2004-03-01 00:00:00
abstract::Studies are reported on the capacity of isolated rat renal papilla (inner medulla) to synthesize and release prostaglandin (PG) E from endogenous and exogenous precursor(s) during development of an essential fatty acid (EFA) deficiency in the rat. Weanling (21-day-old) male Sprague-Dawley rats were fed a fat-free diet...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/BF02533845
更新日期:1978-12-01 00:00:00