Biosynthesis of membrane cholesterol during peripheral nerve development, degeneration and regeneration.

abstract：:Levels of serum lipids and lipoproteins, and the fatty acid composition of plasma phospholipids, were measured in two genetically comparable, but widely separated, populations. The 1975 mortality rates for ischemic heart disease were significantly higher in one of these populations, the Manitoban residents of pure Ice...

journal_title：Lipids

authors： Skúladóttir GV,Gudmundsdóttir S,Olafsson GB,Sigurdsson SB,Sigfússon N,Axelsson J

更新日期：1995-07-01 00:00:00

abstract：:Barth syndrome (BTHS) is an X-linked genetic disease resulting in loss of cardiolipin (Ptd2Gro). Patients may be predisposed to hypoglycemia and exhibit increases in whole-body glucose disposal rates and a higher fat mass percentage. We examined the reasons for this in BTHS lymphoblasts. BTHS lymphoblasts exhibited a ...

journal_title：Lipids

authors： Mejia EM,Zinko JC,Hauff KD,Xu FY,Ravandi A,Hatch GM

更新日期：2017-02-01 00:00:00

abstract：:A method is described for the separation, identification, and quantitative estimation of the individual molecular species occurring in natural lecithin mixtures. Purified lecithin preparations are converted into diglyceride acetates by enzymic dephosphorylation and acetylation. The diglyceride acetates are separated o...

journal_title：Lipids

authors： Kuksis A,Marai L

更新日期：1967-05-01 00:00:00

abstract：:Some studies focused on the effect of the dietary glycemic index on lipoproteins and apolipoproteins in adults; however, little evidence exists among adolescents regarding the effect of a low glycemic index (LGI) diet on apolipoproteins and lipoprotein (a) (Lpa). This study was conducted to evaluate the effect of an L...

journal_title：Lipids

authors： Rouhani MH,Kelishadi R,Hashemipour M,Esmaillzadeh A,Azadbakht L

更新日期：2013-12-01 00:00:00

abstract：:Examination of organelle- and membrane-specific processes such as signal transduction necessitates the use of plasma membrane vesicles with cytoplasmic side-in orientation. We are interested in the structural identity and subcellular localization of in vivo [32P]phosphoric acid ([32Pi])-labeled phosphoinositides, incl...

journal_title：Lipids

authors： Robbins KM,Bhuvarahamurthy N,Pliska-Matyshak G,Murthy PP

更新日期：1999-01-01 00:00:00

abstract：:Vegetable oils are an extremely important agricultural commodity. Their use has risen inexorably for the last 50 years and will undoubtedly be even more prevalent in the future. They have a role not only in foodstuffs but also as renewable chemicals. However, our understanding of their metabolism, and particularly its...

journal_title：Lipids

authors： Chen G,Woodfield HK,Pan X,Harwood JL,Weselake RJ

更新日期：2015-11-01 00:00:00

abstract：:The importance of n-6 and n-3 polyunsaturated fatty acids (PUFA) in neonatal development, particularly with respect to the developing brain and retina, is well known. This review combines recent information from basic science and clinical studies to highlight recent advances in knowledge on PUFA metabolism and areas w...

journal_title：Lipids

authors： Innis SM,Sprecher H,Hachey D,Edmond J,Anderson RE

更新日期：1999-02-01 00:00:00

abstract：:Two unusual lipid classes were detected by thin-layer chromatography in the neutral lipids derived from goat cauda-epididymal sperm plasma membrane. The lipids were identified as wax esters and 1-O-alkyl-2,3-diacylglycerols based on chromatographic properties, identity of their hydrolysis products, and infrared/1H nuc...

journal_title：Lipids

authors： Rana AP,Majumder GC,Misra S,Ghosh A

更新日期：1992-01-01 00:00:00

abstract：:Triglycerides from normal liver, host liver, and heptoma of rats maintained on chow and fat-free diets were subjected to sterospecific analysis. Normal and host liver triglycerides from animals on the same diet did not exhibit significant differences. Fat-free diet reduced polyunsaturated fatty acids in normal and i...

journal_title：Lipids

authors： Wood R

更新日期：1975-07-01 00:00:00

abstract：:Recent work in our lab has shown that the chemoprotective fatty acid, conjugated linoleic acid (CLA), inhibits phorbol ester skin tumor promotion in mice. Because little is known about the deposition of CLA into tissues as well as its biological activity, this study compared the incorporation and biological activity o...

journal_title：Lipids

authors： Liu KL,Belury MA

更新日期：1997-07-01 00:00:00

abstract：:Developing rat brain has the capacity for either delta 9 or delta 6 desaturation of fatty acids. In liver, evidence supports the existence of separate enzymes for each reaction, but it is not known whether in brain delta 9 or delta 6 desaturation of saturated fatty acids involves distinct enzymes. We have used fatty a...

journal_title：Lipids

authors： Cook HW

更新日期：1979-09-01 00:00:00

abstract：:Because of the known advantages of coupling high performance liquid chromatography with mass spectrometry (HPLC-MS) in biological fluids, studies on the reversed-phase HPLC-MS system for direct analysis of conjugated bile acids in human bile samples are described. Ten samples of gallbladder bile of apparently healthy ...

journal_title：Lipids

authors： Mingrone G,Greco AV,Boniforti L,Passi S

更新日期：1983-01-01 00:00:00

abstract：:Wistar male rats were treated for six days with broad spectrum beta-lactam antibiotics, latamoxef, and cefotaxime. On the seventh day, the number of fecal anaerobic microbes decreased, total fecal bile acids decreased, and bile acid pools increased. Secondary bile acids such as beta-hyocholic, hyodeoxycholic, lithocho...

journal_title：Lipids

authors： Hashimoto S,Igimi H,Uchida K,Satoh T,Benno Y,Takeuchi N

更新日期：1996-06-01 00:00:00

abstract：:The degradation of alpha-tocopherol and the formation of alpha-tocopherol and triacylglycerol oxidation products at high temperatures (150-250 degrees C) over a heating period (0-4 h) for a model system ranging between triolein and tripalmitin were modeled by use of an experimental design. The oxidation products of al...

journal_title：Lipids

authors： Verleyen T,Kamal-Eldin A,Dobarganes C,Verhe R,Dewettinck K,Huyghebaert A

更新日期：2001-07-01 00:00:00

abstract：:We evaluated whether CETP and LCAT gene polymorphisms are statistically associated with the high-density lipoprotein (HDL) size distribution, the cholesterol level of HDL subclasses, and the acute coronary syndrome (ACS) susceptibility. Two CETP gene polymorphisms (rs4783961 and rs708272) and one LCAT polymorphism (rs...

journal_title：Lipids

authors： Vargas-Alarcon G,Perez-Mendez O,Herrera-Maya G,Garcia-Sanchez C,Martinez-Rios MA,Peña-Duque MA,Posadas-Sanchez R,Posadas-Romero C,Escobedo G,Fragoso JM

更新日期：2018-02-01 00:00:00

abstract：:In plants, two pathways are utilized for the synthesis of isopentenyl diphosphate (IPP), the universal precursor for isoprenoid biosynthesis. In this paper we review findings and observations made primarily with tobacco BY-2 cells (TBY-2), which have proven to be an excellent system in which to study the two biosynthe...

journal_title：Lipids

authors： Hemmerlin A,Gerber E,Feldtrauer JF,Wentzinger L,Hartmann MA,Tritsch D,Hoeffler JF,Rohmer M,Bach TJ

更新日期：2004-08-01 00:00:00

abstract：:This study investigated a possible role for the epidermal growth factor (EGF) receptor protein tyrosine kinase in phosphoinositide metabolism with plasma membrane vesicles from human epidermoid carcinoma (A431) cells. We found a novel chloroform-soluble product radiolabeled with [gamma-32P]ATP that did not migrate fro...

journal_title：Lipids

authors： Brautigan DL,Randazzo P,Shriner C,Fain JN

更新日期：1985-07-01 00:00:00

abstract：:Triacylglycerols containing linoleate and linolenate found in vegetable oils were synthesized in gram quantities for oxidation studies. Two acylation methods were examined to convert diacylglycerols or monoacylglycerols to the desired triacylglycerols. Acylations with fatty acid and 1,1'-dicyclohexylcarbodiimide in th...

journal_title：Lipids

authors： Awl RA,Frankel EN,Weisleder D

更新日期：1989-10-01 00:00:00

abstract：:Lipases catalyze the hydrolysis and synthesis of triglycerides and their reactions are widely used in industry. The use of ionic liquids has been explored in order to improve their catalytic properties. However, the effect of these compounds on kinetic parameters of lipases has been poorly understood. A study of the k...

journal_title：Lipids

authors： Muñoz PA,Correa-Llantén DN,Blamey JM

更新日期：2015-01-01 00:00:00

abstract：:Recently, lipases have been purified from mammalian, bacterial, fungal and plant sources by different methodologies. Purified lipases subsequently have been characterized for molecular size, metal binding capabilities, glycoside and phosphorus contents, and substrate specificities. Primary structures of several lipase...

journal_title：Lipids

authors： Antonian E

更新日期：1988-12-01 00:00:00

abstract：:The present study determined alpha-tocopherol mass transfer from an alpha-tocopherol-rich emulsion to LDL and HDL, and assessed the potential of different mechanisms to modulate alpha-tocopherol transfers. Emulsion particles rich in alpha-tocopherol were incubated in vitro with physiological concentrations of LDL or H...

journal_title：Lipids

authors： Hacquebard M,Vandenbranden M,Malaisse WJ,Ruysschaert JM,Deckelbaum RJ,Carpentier YA

更新日期：2008-07-01 00:00:00

abstract：:The effects of feeding CLA to hens on newly hatched chick hepatic and carcass lipid content, liver TAG accumulation, and FA incorporation in chick tissues such as liver, heart, brain, and adipose were studied. These tissues were selected owing to their respective roles in lipid assimilation (liver), as a major oxidati...

journal_title：Lipids

authors： Cherian G,Ai W,Goeger MP

更新日期：2005-02-01 00:00:00

abstract：:Gallstone formation and dissolution were studied in a prairie dog model of cholesterol (CH) cholelithiasis. Gallstones were induced in 49 prairie dogs by feeding 1.2% CH in a nutritionally adequate semisynthetic diet for 6 wk (period 1). At 6 wk, gallstones had developed in all animals examined. The diets were modifie...

journal_title：Lipids

authors： Cohen BI,Mosbach EH,McSherry CK,Rzigalinski B,Kuroki S

更新日期：1986-09-01 00:00:00

abstract：:Experimental studies have suggested an important role of the spleen in lipid metabolism, although with controversial results. Our purpose was to analyze the effect of a nutritionally balanced (NB) diet and a diet containing pork fat (PF) as source of lipids on the lipid profile of rats submitted to splenic surgery. Si...

journal_title：Lipids

authors： Dinis AP,Marques RG,Simões FC,Diestel CF,Caetano CE,Secchin DJ,Neto JF,Portela MC

更新日期：2009-06-01 00:00:00

abstract：:Plasma lipidomic studies using high performance liquid chromatography and mass spectroscopy offer detailed insights into metabolic processes. Taking the example of the most abundant plasma lipid class (phosphatidylcholines) we used the rich phenotypic and lipidomic data from the ongoing San Antonio Family Heart Study ...

journal_title：Lipids

authors： Kulkarni H,Meikle PJ,Mamtani M,Weir JM,Barlow CK,Jowett JB,Bellis C,Dyer TD,Johnson MP,Rainwater DL,Almasy L,Mahaney MC,Comuzzie AG,Blangero J,Curran JE

更新日期：2013-05-01 00:00:00

abstract：:A sucrose-rich diet (SRD) induces insulin resistance and dyslipidemia with impaired hepatic glucose production and gluconeogenesis, accompanied by altered post-receptor insulin signaling steps. The aim of this study was to examine the effectiveness of fish oil (FO) to reverse or improve the impaired hepatic glucose me...

journal_title：Lipids

authors： Hein GJ,Chicco A,Lombardo YB

更新日期：2012-02-01 00:00:00

abstract：:The schweinfurthins have potent antiproliferative activity in multiple glioblastoma multiforme (GBM) cell lines; however, the mechanism by which growth is impeded is not fully understood. Previously, we demonstrated that the schweinfurthins reduce the level of key isoprenoid intermediates in the cholesterol biosynthet...

journal_title：Lipids

authors： Kuder CH,Weivoda MM,Zhang Y,Zhu J,Neighbors JD,Wiemer DF,Hohl RJ

更新日期：2015-12-01 00:00:00

abstract：:The current study evaluated the composition and relationships of polyunsaturated fatty acid biohydrogenation products (PUFA-BHP) from the perirenal (PRF) and subcutaneous fat (SCF) of yearling steers fed a 70 % grass hay diet with concentrates containing either sunflower-seed (SS) or flaxseed (FS). Analysis of varianc...

journal_title：Lipids

authors： Mapiye C,Aalhus JL,Turner TD,Rolland DC,Basarab JA,Baron VS,McAllister TA,Block HC,Proctor SD,Dugan ME

更新日期：2014-03-01 00:00:00

abstract：:A specific radioimmunoassay for platelet-activating factor (PAF) sensitive in the range 10-1000 pg (0.02-2 pmoles) has been developed. Detailed quantitative hapten inhibition studies showed specificity for the acetyl group at C-2 of PAF, a requirement for the ether linkage at C-1 and some tolerance for substituents on...

journal_title：Lipids

authors： Baldo BA,Smal MA,McCaskill AC

更新日期：1991-12-01 00:00:00

abstract：:Type 2 diabetes and dyslipidemia are risk factors for cardiovascular disease. However, mechanisms by which hypertriglyceridemia influences atherogenesis remain unclear. We examined effects of dyslipidemic diabetic serum on macrophage lipid accumulation as a model of foam cell formation. Normal human macrophages were c...

journal_title：Lipids

authors： Wong BX,Kyle RA,Myhill PC,Croft KD,Quinn CM,Jessup W,Yeap BB

更新日期：2011-10-01 00:00:00