Sterospecific analysis of hepatoma, host liver, and normal rat liver triglycerides from animals on chow and fat free diets.

Abstract:

:Triglycerides from normal liver, host liver, and heptoma of rats maintained on chow and fat-free diets were subjected to sterospecific analysis. Normal and host liver triglycerides from animals on the same diet did not exhibit significant differences. Fat-free diet reduced polyunsaturated fatty acids in normal and in host liver triglycerides. Each position of hepatoma and liver triglyceride glycerol exhibited a characteristic fatty acid composition. Palmitate concentrations were reduced dramatically and stearate levels were increased significantly at the 1 position of hepatoma triglycerides, relative to the corresponding position of liver triglycerides which were affected little by diet ot tumor. Except for higher percentages of C-20 and higher fatty acids, common to all three positions, the composition of hepatoma triglycerides at the 2 position appeared normal. The 3 position of hepatoma triglycerides contained significantly higher percentages of stearate than liver. Data obtained previously for Ehrlich ascites cell triglycerides were in good agreement with this hepatoma. Data from these two neoplasms suggest that the metabolic system that regulates or controls the fatty acid composition at the 1 and 3 positions of normal tissue triglycerides does not function normally in neoplasms.

journal_name

Lipids

journal_title

Lipids

authors

Wood R

doi

10.1007/BF02532444

subject

Has Abstract

pub_date

1975-07-01 00:00:00

pages

404-8

issue

7

eissn

0024-4201

issn

1558-9307

journal_volume

10

pub_type

杂志文章

相关文献

LIPIDS文献大全
  • Cis-5-polyenoic acids inLarix leptolepis seed oil.

    abstract::cis-5,cis-9-Octadecadienoic acid (2.7%) andcis-5,cis-9,cis-12-octadecatrienoic acid (24.9%) are present in the seed oil ofLarix leptolepis. The double bond positions were identified by ozonolysis and by gas chromatography-mass spectrometry of methoxy derivatives. Small quantities of branched chain acids of various cha...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02532446

    authors: Plattner RD,Spencer GF,Kleiman R

    更新日期:1975-07-01 00:00:00

  • Modulation of prostaglandin synthesis in rat peritoneal macrophages with omega-3 fatty acids.

    abstract::In view of the findings that omega 3 fatty acids inhibit the synthesis of prostaglandins (PG) from arachidonic acid (20:4 omega 6) and that among immunologically active cells, the macrophage is a major producer of PG, we undertook a study of the effect of dietary alpha-linolenic acid (18:3 omega 3) on PG synthesis in ...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02535390

    authors: Magrum LJ,Johnston PV

    更新日期:1983-08-01 00:00:00

  • Intermembrane cholesterol transfer: role of sterol carrier proteins and phosphatidylserine.

    abstract::The effect of phosphatidylserine and sterol carrier proteins on cholesterol exchange was determined using an assay not requiring separation of donor and acceptor membrane vesicles. Sterol carrier protein-2 (SCP2, also called nonspecific lipid transfer protein), but not fatty acid binding protein (FABP, also called ste...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02544032

    authors: Schroeder F,Butko P,Hapala I,Scallen TJ

    更新日期:1990-11-01 00:00:00

  • Leaf wax of oats.

    abstract::Leaf wax of oats (Kelsey variety) consists of hydrocarbons (5%), esters (10%), free alcohols (45%), free acids (2.5%), β-diketone (5.5%), hydroxy-β-diketones (2.5%), and unidentified (29%). Wax on leaf blades contains more free alcohols than wax on leaf sheaths, and wax on the flag leaf sheath contains more β-diketone...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02533144

    authors: Tulloch AP,Hoffman LL

    更新日期:1973-11-01 00:00:00

  • Hydroxylation of secondary bile acids in the perfused prairie dog liver.

    abstract::Taurolithocholic acid and deoxycholic acid were perfused into isolated prairie dog livers. Taurolithocholic acid was 7 alpha-hydroxylated to form taurochenodeoxycholic acid, whereas deoxycholic acid was conjugated and 7 alpha-hydroxylated to form taurocholic acid. The low concentrations of secondary bile acids observe...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02534573

    authors: Cohen BI,Singhal AK,Mongelli J,Rothschild MA,McSherry CK,Mosbach EH

    更新日期:1983-12-01 00:00:00

  • Effects of parenteral nutrition with high doses of linoleate on the developing human liver and brain.

    abstract::The developmental changes in the fatty acid composition of ethanolamine phosphoglycerides (EPG) and choline phosphoglycerides (CPG) were studied in the liver and brain of 18 newborn infants with gestational ages ranging from 20 to 44 wk. A small group of five newborns receiving total parenteral nutrition (TPN) with hi...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02537290

    authors: Martínez M,Ballabriga A

    更新日期:1987-03-01 00:00:00

  • Protective Effect of Unsaturated Fatty Acids on Palmitic Acid-Induced Toxicity in Skeletal Muscle Cells is not Mediated by PPARδ Activation.

    abstract::Unsaturated free fatty acids (FFA) are able to prevent deleterious effects of saturated FFA in skeletal muscle cells although the mechanisms involved are still not completely understood. FFA act as endogenous ligands of peroxisome proliferator-activated receptors (PPAR), transcription factors regulating the expression...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/s11745-015-4058-0

    authors: Tumova J,Malisova L,Andel M,Trnka J

    更新日期:2015-10-01 00:00:00

  • Determination of the specific positions ofcis andtrans double bonds in polyenes.

    abstract::A method is described for the determination of the positions and geometric configurations of double bonds in polyunsaturated fatty acids. The procedure consists of three steps: 1) Partial reduction of the double bonds with hydrazine under conditions which give high yields of monoenes. 2) Isolation of thecis- and thetr...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02532998

    authors: Privett OS,Nickell EC

    更新日期:1966-03-01 00:00:00

  • Quantitative determination of alk-1-enyl- and alkyl-glyceryl ethers in neutral lipids and phospholipids.

    abstract::A quantitative method for the simultaneous determination of alk-l-enyl- and alkyl-glyceryl ethers is described. Complete hydrogenolysis of carboxylate and phosphate esters of neutral lipids and phospholipids was achieved with lithium aluminum hydride. The hydrogenolysis products of the glyceryl ether containing lipids...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02531729

    authors: Wood R,Snyder F

    更新日期:1968-03-01 00:00:00

  • The effect of neurotensin on the concentration of cholesterol and bile acids in the guinea pig.

    abstract::In guinea pigs, total plasma cholesterol concentrations increased above the control values after single intravenous injections and after 3 days of continuous subcutaneous administration of neurotensin (NT). A high dose of NT (125 pmol/100 g body weight) induced tachycardia and severe respiratory distress; the lowest d...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02534468

    authors: Peric-Golia L,Gardner CF,Wilson DE,Peric-Golia M

    更新日期:1984-10-01 00:00:00

  • The effect of various dietary factors on the size distribution of lymph fat particles in rat.

    abstract::By means of cellulose acetate electrophoresis and measurement of radio-activity, lipoproteins (d less than or equal to 1,006) of lymph collected from rats fed a diet containing fats added to labeled fatty acids for 20-24 hr, have been separated into two kinds differing in their size. Fats with different saturated and ...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02535449

    authors: Boquillon M,Paris R,Clement J

    更新日期:1977-06-01 00:00:00

  • Effects of administration of hypolipidemic agent, 2,2'''- [ (1-methyl-4, 4-diphenylbutylidene) bis (p-phenyleneoxy)] bistriethylamine oxalate (SQ 10,591) upon cholesterol esterification by aorta, adrenal, and testes of cholesterol-fed rabbits].

    abstract::Administration of 2,2'''-([1-methyl-4, 4-diphenylbutylidene] bis(p-phenyl-eneoxy]) bistriethylamine oxalate (SQ 10,591) at 20 mg/Kg daily for 5 days to cholesterol-fed rabbits resulted in no change in aortic microsomal cholesterol esterification with a palmitoyl coenzyme A substrate or of aortic mitochondrial choleste...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02532164

    authors: Morin RJ

    更新日期:1975-02-01 00:00:00

  • Identification of diacylglycerol acyltransferase inhibitors from Rosa centifolia petals.

    abstract::Diacylglycerol acyltransferase (DGAT) catalyzes the final step of triacylglycerol (TAG) synthesis, and is considered as a potential target to control hypertriglyceridemia or other metabolic disorders. In this study, we found that the extract of rose petals suppressed TAG synthesis in cultured cells, and that the extra...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/s11745-011-3559-8

    authors: Kondo H,Hashizume K,Shibuya Y,Hase T,Murase T

    更新日期:2011-08-01 00:00:00

  • Hyperthyroidism affects lipid metabolism in lactating and suckling rats.

    abstract::Two per thousand pregnant women have hyperthyroidism (HT), and although the symptoms are attenuated during pregnancy, they rebound after delivery, affecting infant development. To examine the effects of hyperthyroidism on lactation, we studied lipid metabolism in maternal mammary glands and livers of hyperthyroid rats...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/s11745-001-0787-4

    authors: Varas SM,Jahn GA,Giménez MS

    更新日期:2001-08-01 00:00:00

  • Maternal high-fat-diet programs rat offspring liver fatty acid metabolism.

    abstract::In offspring exposed in utero to a maternal diet high in fat (HF), we have previously demonstrated that despite similar birth weights, HF adult offspring at 6 months of age had significantly higher body weights, greater adiposity, and increased triacylglycerol (TAG) levels as compared to controls. We hypothesized that...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/s11745-015-4018-8

    authors: Seet EL,Yee JK,Jellyman JK,Han G,Ross MG,Desai M

    更新日期:2015-06-01 00:00:00

  • Mechanism of anesthesia: the potency of four derivatives of octane corresponds to their hydrogen bonding capacity.

    abstract::The anesthetic potency of four derivatives of n-octane was measured by tadpole righting reflex and expressed as effective millimolar concentration of drug in membrane, EDM50. Potency diminished (ED50 increased) in this order: 1-octanol, EDM50 = 5.5; 1-(2-methoxyethoxy)octane, EDM50 = 28; 1-methoxyoctane, EDM50 = 61; a...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02534936

    authors: Brockerhoff H,Brockerhoff S,Box LL

    更新日期:1986-06-01 00:00:00

  • Dietary guar gum reduces lymph flow and diminishes lipid transport in thoracic duct-cannulated rats.

    abstract::Guar gum has a well-recognized hypolipidemic effect. This effect is thought to be due to the physicochemical properties of guar gum, which may cause changes in adsorption of lipids or the viscosity of the intestinal contents. Guar gum is a non-specific absorption inhibitor of any type of lipid-soluble compound. Perman...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/s11745-011-3570-0

    authors: Shirouchi B,Kawamura S,Matsuoka R,Baba S,Nagata K,Shiratake S,Tomoyori H,Imaizumi K,Sato M

    更新日期:2011-08-01 00:00:00

  • Effects of beta-lactam antibiotics on intestinal microflora and bile acid metabolism in rats.

    abstract::Wistar male rats were treated for six days with broad spectrum beta-lactam antibiotics, latamoxef, and cefotaxime. On the seventh day, the number of fecal anaerobic microbes decreased, total fecal bile acids decreased, and bile acid pools increased. Secondary bile acids such as beta-hyocholic, hyodeoxycholic, lithocho...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02523830

    authors: Hashimoto S,Igimi H,Uchida K,Satoh T,Benno Y,Takeuchi N

    更新日期:1996-06-01 00:00:00

  • Nonmembrane associated dolichol in rat liver.

    abstract::The distribution of dolichol in rat liver was studied. Upon high-speed centrifugation, 9% of the total tissue dolichol was recovered in the supernatant. Dolichol was enclosed in vesicles and in lipidic particles which were isolated by gel filtration and density gradient centrifugation. The particles had a diameter of ...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02537050

    authors: Löw P,Peterson E,Edlund C,Brunk U,Appelkvist EL

    更新日期:1992-01-01 00:00:00

  • Accumulation of docosahexaenoic acid in phosphatidylserine is selectively inhibited by chronic ethanol exposure in C-6 glioma cells.

    abstract::Neuronal membranes are highly enriched with docosahexaenoic acid (22:6n-3), and its content can be altered by ethanol consumption. We have previously reported that the 22:6n-3 status in membrane affects the biosynthesis of phosphatidylserine (PS), a phospholipid class which contains an exceptionally high proportion of...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02664769

    authors: Kim HY,Hamilton J

    更新日期:2000-02-01 00:00:00

  • Triticale dried distillers' grain increases alpha-linolenic acid in subcutaneous fat of beef cattle fed oilseeds.

    abstract::This study investigated the effect of triticale dried distillers' grain with solubles (DDGS), flax (FS) and sunflower (SS) seed on growth and the fatty acid profile of subcutaneous (SQ) fat in individually housed steers (n = 15 per diet) fed ad libitum (DM basis); (1) control (CON) 90% barley grain + 10% barley silage...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/s11745-012-3720-z

    authors: He ML,Sultana H,Oba M,Kastelic JP,Dugan ME,McKinnon JJ,McAllister TA

    更新日期:2012-12-01 00:00:00

  • Composition of lipids of bovine optic nerve.

    abstract::Lipids from bovine optic nerve were analyzed. The total content of 16.5% by weight included 27.2% nonpolar lipids, 26.1% glycolipids, and 46.7% phospholipids by weight. Free cholesterol was the major component of the nonpolar lipid fraction. The cerebrosides, 73.5% of total glycolipids, were separated by thin layer ch...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02533745

    authors: Das SK,Steen ME,McCullough MS,Bhattacharyya DK

    更新日期:1978-10-01 00:00:00

  • Isoprenoid fatty acids from marine sponges. Are sponges selective?

    abstract::The burrowing sponges Anthosigmella varians and Spheciospongia vesparium were found to be rich in the isoprenoid phospholipid fatty acid 4,8,12-trimethyltridecanoic (5.2% and 23%, respectively, of the total fatty acid composition), while the burrowing sponge Chondrilla nucula and the demosponge Agelas dispar contained...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02533980

    authors: Carballeira NM,Maldonado L,Porras B

    更新日期:1987-10-01 00:00:00

  • Effect of low vitamin A status on fat deposition and fatty acid desaturation in beef cattle.

    abstract::A group of Angus beef cattle was removed from temperate pastures and fed a very low beta-carotene cereal-based ration in a feedlot for over 300 d. Half the group was supplemented weekly with retinyl palmitate (at the rate of 60,000 IU vitamin A/100 live weight (LW)/day), sufficient to offset clinical vitamin A deficie...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/s11745-006-5107-5

    authors: Siebert BD,Kruk ZA,Davis J,Pitchford WS,Harper GS,Bottema CD

    更新日期:2006-04-01 00:00:00

  • Dietary TAG source and level affect performance and lipase expression in larval sea bass (Dicentrarchus labrax).

    abstract::The influence of dietary TAG source (fish oil, triolein, and coconut oil) and level (7.5 and 15% of the diet) on growth, lipase activity, and mRNA level was studied in sea bass larvae, from mouth opening until day 24 and from day 37 to 52. Fish oil and triolein induced better growth in both experiments, this being sig...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/s11745-004-1250-2

    authors: Morais S,Cahu C,Zambonino-Lnfante JL,Robin J,Rønnestad I,Dinis MT,Conceição LE

    更新日期:2004-05-01 00:00:00

  • Biochemical modifications and transcriptional alterations attendant to sterol feeding in Phytophthora parasitica.

    abstract::Phytophthora species are eukaryotic sterol auxotrophs that possess the ability to grow, albeit poorly, in the complete absence of sterols. Growth of Phytophthora is often improved substantially when an exogenous source of sterol is provided. Additionally, sterols may be required for sexual and asexual sporulation in P...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/s11745-000-0519-9

    authors: Dotson WD,Tove SR,Parks LW

    更新日期:2000-03-01 00:00:00

  • Epicoprostanol found in adipocere from five human autopsies.

    abstract::Adipocere formation is well known as a later postmortem change. We collected adipocere from five male victims which had been submerged under the sea or fresh water for 1 mon to 4 yr. Fresh subcutaneous fat of a male victim who died from a cerebral contusion was used as the control. The samples were homogenized, and th...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/s11745-997-0148-3

    authors: Adachi J,Ueno Y,Miwa A,Asano M,Nishimura A,Tatsuno Y

    更新日期:1997-11-01 00:00:00

  • Apolipoprotein E polymorphism: automated determination of apolipoprotein E2, E3, and E4 isoforms.

    abstract::Apolipoprotein E (apo E) plays an essential role in lipoprotein metabolism, where it is involved in the clearance of chylomicrons and very low density lipoproteins. Apart from some rare variants, apo E exists in three common isoforms (E2, E3, and E4). The different isoforms have not only been associated with different...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/s11745-000-0500-7

    authors: Wiebe C,Holzem G,Wielckens K,Klingler KR

    更新日期:2000-01-01 00:00:00

  • Uptake and metabolism of exogenous eicosa-8,11,14-trienoic acid in minimal deviation hepatoma 7288 C cells.

    abstract::Minimal deviation hepatoma 7288 C cells were cultured in Swim's medium containing 10% serum for 48 hr. The growth medium was replaced with serum free media containing different concentrations of [1-14C] eicosa-8,11,14-trienoic acid and the cells were incubated for 24 hr. Incorporation into cell lipids, oxidation to CO...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02532312

    authors: Gaspar G,de Alaniz MJ,Brenner RR

    更新日期:1975-12-01 00:00:00

  • Conjugated linoleic acids and CLA-containing phospholipids inhibit NO formation in aortic endothelial cells.

    abstract::This study examined the effects of five CLA isomers and the non-conjugated LA on nitric oxide (NO) production, an important modulator of vasodilation, inflammation, and cytotoxicity. Bovine aortic endothelial cells (BAECs) were pretreated with pure CLAs (c9, c11-, c9, t11-, t9, t11-, t10, c12-, c11, c13-CLA) and the n...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/s11745-008-3160-y

    authors: Jenko KJ,Vanderhoek JY

    更新日期:2008-04-01 00:00:00