Modulation of prostaglandin synthesis in rat peritoneal macrophages with omega-3 fatty acids.

abstract：:A new spectrophotometric assay for determining the activity of acylglycerol hydrolases (lipases, E.C. 3.1.1.3) was developed and optimized for yeast lipase (Candida cylindracea). Studies with porcine pancreatic lipase were also conducted and the influence of various detergents and divalent cations on the assay was eva...

journal_title：Lipids

authors： Rogel AM,Stone WL,Adebonojo FO

更新日期：1989-06-01 00:00:00

abstract：:Southern bluefin tuna (SBT, Thunnus maccoyii) aquaculture is a highly valuable industry, but research on these fish is hampered by strict catch quotas and the limited success of captive breeding. To address these limitations, we have developed a SBT cell line (SBT-E1) and here we report on fatty acid metabolism in thi...

journal_title：Lipids

authors： Scholefield AM,Schuller KA

更新日期：2014-07-01 00:00:00

abstract：:FA ethyl esters (FAEE) are nonoxidative metabolites of ethanol produced by the esterification of FA and ethanol. FAEE have been implicated as mediators of ethanol-induced organ damage in vivo and in vitro, and are markers of ethanol intake. Upon ethanol intake, FAEE are synthesized in the liver and pancreas in signifi...

journal_title：Lipids

authors： Hasaba A,Cluette-Brown JE,Laposata M

更新日期：2003-10-01 00:00:00

abstract：:Lipoprotein(a) [Lp(a)] represents a class of lipoprotein particles having as a protein moiety apoB-100 linked by a single disulfide bond to apolipoprotein(a) [apo(a)], a multikringle structure with a high degree of homology with plasminogen. A recognized feature of Lp(a) is its instability on storage caused by attenda...

journal_title：Lipids

authors： Scanu AM,Hinman J,Pfaffinger D,Edelstein C

更新日期：2004-06-01 00:00:00

abstract：:The purpose of this study was to examine the effect of dietary docosahexaenoic acid (DHA), in the absence of eicosapentaenoic acid, on human immune response (IR). A 120-d study with 11 healthy men was conducted at the Metabolic Research Unit of the Western Human Nutrition Research Center. Four subjects (control group)...

journal_title：Lipids

authors： Kelley DS,Taylor PC,Nelson GJ,Mackey BE

更新日期：1998-06-01 00:00:00

abstract：:Incorporation of [14C] from acetoacetate, D(-)- and L(+)-3-hydroxybutyrate, glucose, glutamine, acetate and palmitate in cellular lipids were studied in cultures in human diploid fibroblasts (HDF). The results showed that acetoacetate was 2-10 times more effective as a lipogenic precursor than was either D- or L-3-hyd...

journal_title：Lipids

authors： Reed WD,Zielke HR,Baab PJ,Ozand PT

更新日期：1981-09-01 00:00:00

abstract：:In the present study we evaluated the uptake of ALA and its conversion to EPA + DHA in rats given linseed oil (LSO) in native form or as a microemulsion in whey protein or in lipoid. In a single oral dose study in which rats maintained on rodent pellets deficient in ω-3 fatty acids were intubated with 0.35 g LSO in li...

journal_title：Lipids

authors： Sugasini D,Devaraj VC,Ramesh M,Lokesh BR

更新日期：2014-03-01 00:00:00

abstract：:In offspring exposed in utero to a maternal diet high in fat (HF), we have previously demonstrated that despite similar birth weights, HF adult offspring at 6 months of age had significantly higher body weights, greater adiposity, and increased triacylglycerol (TAG) levels as compared to controls. We hypothesized that...

journal_title：Lipids

authors： Seet EL,Yee JK,Jellyman JK,Han G,Ross MG,Desai M

更新日期：2015-06-01 00:00:00

abstract：:Biosynthesis of peripheral nerve cholesterol was investigated by the in vivo and in vitro incorporation of [1-14C]-acetate into sciatic endoneurium of normal rats during development, degeneration and regeneration. Labeled sterols were rapidly formed (less than 10 min) within the endoneurial portion of sciatic nerve af...

journal_title：Lipids

authors： Yao JK

更新日期：1988-09-01 00:00:00

abstract：:Apolipoprotein (apoB) plays a fundamental role in the transport and metabolism of plasma triacylglycerols (TAGs) and cholesterol. Several apoB polymorphic sites have been studied for their potential use as markers for coronary heart disease in the population. In view of the importance of apoB in postprandial metabolis...

journal_title：Lipids

authors： Pérez-Martínez P,Pérez-Jiménez F,Ordovás JM,Moreno JA,Marín C,Moreno R,Jiménez-Gómez Y,Paniagua JA,López-Miranda J

更新日期：2007-03-01 00:00:00

abstract：:Isolated perfused rat lungs liberated fatty acids at a rate of 15 mumol/hr during perfusion of triglyceride-rich medium through the pulmonary vascular bed. About 80% of this activity seemed to result from lipoprotein lipase and 20% to hormone-sensitive lipase. Ventilation of the lungs with cigarette smoke instead of a...

journal_title：Lipids

authors： Hartiala J,Viikari J,Hietanen E,Toivonen H,Uotila P

更新日期：1980-07-01 00:00:00

abstract：:The oxidation of free DHA, DHA mixed with PC, and DHA incorporated into PC, PE, or TG was evaluated to determine which lipid provided DHA with the best protection against oxidation. DHA was either situated at the sn-1 position, sn-2 position, or both positions of the phospholipid, whereas the TG contained DHA at all p...

journal_title：Lipids

authors： Lyberg AM,Fasoli E,Adlercreutz P

更新日期：2005-09-01 00:00:00

abstract：:Insulin and dietary fructose independently induce stearoyl-CoA desaturase 1 (SCD1) gene expression in diabetic mouse liver. In the present study, we again used diabetic mice and supplemented a high fructose diet with polyunsaturated fatty acids (PUFA) to determine the selective repression of SCD1 gene expression by di...

journal_title：Lipids

authors： Waters KM,Ntambi JM

更新日期：1996-03-01 00:00:00

abstract：:New methods and analytical approaches are important to challenge and/or validate established beliefs in any field including the metabolism of polyunsaturated fatty acids (PUFA; polyunsaturates). Four methods that have recently been applied toward obtaining a better understanding of the homeostasis of PUFA include the ...

journal_title：Lipids

authors： Cunnane SC

更新日期：2001-09-01 00:00:00

abstract：:The stereochemistry of fat digestion and absorption was investigated in rats with thoracic duct fistulas, after feeding synthetic triacylglycerol or alkyldiacylglycerol. After feeding 1,2-dilauroyl-3-oleoyl-sn-glycerol, dilauroyloleoylglycerol and lauroyldioleoylglycerol were the most abundant chyle triacylglycerols. ...

journal_title：Lipids

authors： Akesson B,Gronowitz S,Herslof B,Ohlson R

更新日期：1978-05-01 00:00:00

abstract：:A methodology combining finger-pricked blood sampling, microwave accelerated fatty acid assay, fast gas chromatography data acquisition, and automated data processing was developed, evaluated and applied to a population study. Finger-pricked blood was collected on filter paper previously impregnated with 0.05 mg of th...

journal_title：Lipids

authors： Lin YH,Hanson JA,Strandjord SE,Salem NM,Dretsch MN,Haub MD,Hibbeln JR

更新日期：2014-08-01 00:00:00

abstract：:Fatty acid compositions of polar lipids and triacylglycerols isolated from eggs of the sea urchin, Arbacia punctulata, were examined before and 15 min after insemination. The main fatty acids present in polar lipids and triacylglycerols were palmitate, palmitoleate, eicosaenoate, arachidonate and eicosapentaenoate, wh...

journal_title：Lipids

authors： Metzman MS,Mastroianni A,Strauss JF

更新日期：1978-11-01 00:00:00

abstract：:The accumulation of (1-palmitoyl)lysophosphatidylcholine, lysolecithin, in gallbladder bile was observed during the first week of cholesterol-induced experimental cholelithiasis using the prairie dog model for cholesterol gallstone formation. Gallbladder fluid transport function decreased as bile lysolecithin concentr...

journal_title：Lipids

authors： Rutledge FA 2nd,Hickman DM,Dunn JJ,Frey CF,Matson RS

更新日期：1981-10-01 00:00:00

abstract：:CDPcholine:1,2-diacylglycerol cholinephosphotransferase (EC 2.7.8.2) is located on the cytoplasmic side of the endoplasmic reticulum, and catalyzes the final step in the synthesis of phosphatidylcholine via the CDPcholine pathway. The enzyme was solubilized from hamster liver microsomes by 3% Triton QS-15, and partial...

journal_title：Lipids

authors： O KM,Choy PC

更新日期：1990-02-01 00:00:00

abstract：:Two unusual lipid classes were detected by thin-layer chromatography in the neutral lipids derived from goat cauda-epididymal sperm plasma membrane. The lipids were identified as wax esters and 1-O-alkyl-2,3-diacylglycerols based on chromatographic properties, identity of their hydrolysis products, and infrared/1H nuc...

journal_title：Lipids

authors： Rana AP,Majumder GC,Misra S,Ghosh A

更新日期：1992-01-01 00:00:00

abstract：:Peroxidation of intact human erythrocytes by t-butylhydroperoxide (tBHP)) was studied. By incubation of the erythrocytes with 1 mM tBHP, reduced glutathione (GSH) was exhausted within 1 min, and tocopherols (Toc) and phospholipids (PL) decreased to nearly their lowest levels (in this study) within 5 min. The rate of d...

journal_title：Lipids

authors： Mawatari S,Murakami K

更新日期：2001-01-01 00:00:00

abstract：:Meal fatty acids have been shown to modulate the size and composition of triacylglycerol (TAG)-rich lipoproteins influencing the magnitude and duration of the postprandial plasma TAG response. As a result there is considerable interest in the origin of these meal fatty-acid induced differences in particle composition....

journal_title：Lipids

authors： Jackson KG,Bateman PA,Yaqoob P,Williams CM

更新日期：2009-12-01 00:00:00

abstract：:Facile procedures are described for nearly quantitative conversion of saturated and unsaturated fatty aldehydes to their dimethyl acetals, and vice versa, at low temperatures. The methods are based on the chemical behavior of aldehydes and dimethyl acetals in 100% sulfuric acid. Under the experimental conditions descr...

journal_title：Lipids

authors： Mahadevan V,Viswanathan CV,Lundberg WO

更新日期：1966-09-01 00:00:00

abstract：:Primary amines (ammonia, methyl, propyl, octyl, octadecyl, phenyl, benzyl, phenethyl) including methyl esters of amino acids (glycine, DL-alanine, L-valine, L-leucine, L-tyrosine, and L-methionine), and secondary amines (dimethyl, diethyl, dipropyl, diisopropyl, dioctyl, and diphenyl) attack regiospecifically the cent...

journal_title：Lipids

authors： Jie MS,Lau MM

更新日期：2000-10-01 00:00:00

abstract：:Adipocere formation is well known as a later postmortem change. We collected adipocere from five male victims which had been submerged under the sea or fresh water for 1 mon to 4 yr. Fresh subcutaneous fat of a male victim who died from a cerebral contusion was used as the control. The samples were homogenized, and th...

journal_title：Lipids

authors： Adachi J,Ueno Y,Miwa A,Asano M,Nishimura A,Tatsuno Y

更新日期：1997-11-01 00:00:00

abstract：:Using the spectrofluorimetric method described by Wittenauer et al. [Wittenauer, L.A., Shirai, K., Jackson, R.L., and Johnson, J.D. (1984) Biochem. Biophys. Res. Commun. 118, 894-901] for phospholipase A2 (PLA2) measurement, we have detected a phospholipase activity in Ailsa Craig and in mutant rin tomatoes at their n...

journal_title：Lipids

authors： Rouet-Mayer MA,Valentova O,Simond-Côte E,Daussant J,Thévenot C

更新日期：1995-08-01 00:00:00

abstract：:Dietary fat intake influences plasma glucose concentration through modifying glucose uptake and utilization by adipose and skeletal muscle tissues. In this paper, we studied the effects of a low-fat diet on diaphragm GLUT4 expression and fatty acid composition in control and streptozotocin-induced diabetic rats. Contr...

journal_title：Lipids

authors： Girón MD,Salto R,Hortelano P,Periago JL,Vargas AM,Suárez MD

更新日期：1999-08-01 00:00:00

abstract：:Twenty-three of 86 strains of lactic acid bacteria transformed linoleic acid into hydroxy FA. Two distinct conversion pathways were in operation. Two strains of Lactobacillus acidophilus and a strain of Pediococcus pentosaceus produced 13(S)-hydroxy-9-octadecenoic acid 113(S)-OH 18:11 and 10,13dihydroxyoctadecanoic ac...

journal_title：Lipids

authors： Kishimoto N,Yamamoto I,Toraishi K,Yoshioka S,Saito K,Masuda H,Fujita T

更新日期：2003-12-01 00:00:00

abstract：:Neutral glycolipids (NGL) are promising diagnostic markers of human gliomas, but differences in NGL with age and sex have not been examined. Previous work demonstrated that ceramide dihexosides (CDH) levels in mouse kidney are age- and sex-dependent, probably due to levels of sex hormones. We quantitated CDH in 181 hu...

journal_title：Lipids

authors： Yates AJ,Franklin TK,Scheithauer BW,Burger PC,Pearl DK

更新日期：1999-01-01 00:00:00

abstract：:Factors involved in reduced glutathione (GSH) and vitamin E-mediated inhibition of NADPH-dependent rat liver microsomal lipid peroxidation were examined. Lipid peroxidation was monitored over a time-course of 180 min by thiobarbituric acid reactive product formation. The addition of 5 mM GSH to the reaction system con...

journal_title：Lipids

authors： Graham KS,Reddy CC,Scholz RW

更新日期：1989-11-01 00:00:00