Cigarette smoke affects lipolytic activity in isolated rat lungs.

Abstract:

:Isolated perfused rat lungs liberated fatty acids at a rate of 15 mumol/hr during perfusion of triglyceride-rich medium through the pulmonary vascular bed. About 80% of this activity seemed to result from lipoprotein lipase and 20% to hormone-sensitive lipase. Ventilation of the lungs with cigarette smoke instead of air during the perfusion reduced fatty acid liberation by 23%. Pre-exposure of rats to cigarette smoke for either 1 or 10 days did not cause significant changes in lung lipolytic activity compared to sham-exposed controls.

journal_name

Lipids

journal_title

Lipids

authors

Hartiala J,Viikari J,Hietanen E,Toivonen H,Uotila P

doi

10.1007/BF02534227

subject

Has Abstract

pub_date

1980-07-01 00:00:00

pages

539-43

issue

7

eissn

0024-4201

issn

1558-9307

journal_volume

15

pub_type

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