Abstract:
:Neutral glycolipids (NGL) are promising diagnostic markers of human gliomas, but differences in NGL with age and sex have not been examined. Previous work demonstrated that ceramide dihexosides (CDH) levels in mouse kidney are age- and sex-dependent, probably due to levels of sex hormones. We quantitated CDH in 181 human gliomas and found significant differences with sex and age, particularly menopause and male puberty. This emphasizes the importance of assessing results of studies on glycolipids in disease states with respect to age and sex in order to avoid erroneous conclusions concerning the relationship of glycolipid composition with diagnosis and pathogenesis.
journal_name
Lipidsjournal_title
Lipidsauthors
Yates AJ,Franklin TK,Scheithauer BW,Burger PC,Pearl DKdoi
10.1007/s11745-999-330-7subject
Has Abstractpub_date
1999-01-01 00:00:00pages
1-4issue
1eissn
0024-4201issn
1558-9307journal_volume
34pub_type
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