Reduced glutathione effects on alpha-tocopherol concentration of rat liver microsomes undergoing NADPH-dependent lipid peroxidation.

abstract：:An increased amount of phospholipids remained attached on delipidated apolipoprotein B originated from oxidized low density lipoprotein (LDL). 31P nuclear magnetic resonance analysis of such apolipoprotein showed an organic phosphorus peak at -0.55 ppm, which suggests the formation of adducts (most probably Schiff bas...

journal_title：Lipids

authors： Karakatsani AI,Liapikos TA,Troganis AN,Tsoukatos DC

更新日期：1998-12-01 00:00:00

abstract：:Mitochondrial cytochrome P450 enzymes (CYP or P450, EC 1.14.13.15) play an important role in metabolism of cholesterol. CYP27A1 hydroxylates cholesterol at position 27 and, thus, initiates cholesterol removal from many extrahepatic tissues. CYP11A1 is a steroidogenic P450 that converts cholesterol to pregnenolone, the...

journal_title：Lipids

authors： Pikuleva IA,Mast N,Liao WL,Turko IV

更新日期：2008-12-01 00:00:00

abstract：:Various physical fractions of the barley kernel were fed to one-day-old female and male chickens to determine their effect on hepatic beta-hydroxy-beta-methylglutaryl coenzyme A (HMG-CoA) reductase, cholesterol 7 alpha-hydroxylase and the lipogenic enzymes, acetyl-CoA carboxylase (ACX), malic enzyme (ME), citrate-clea...

journal_title：Lipids

authors： Burger WC,Qureshi AA,Prentice N,Elson CE

更新日期：1982-12-01 00:00:00

abstract：:Stearoyl-CoA desaturase (SCD) is a regulatory enzyme in lipogenesis, catalyzing the rate-limiting step in the overall de novo synthesis of monounsaturated FA, mainly oleate and palmitoleate from stearoyl- and palmitoyl-CoA, respectively. Oleate and palmitoleate are the major monounsaturated FA of membrane phospholipid...

journal_title：Lipids

authors： Ntambi JM,Miyazaki M,Dobrzyn A

更新日期：2004-11-01 00:00:00

abstract：:[1-14C]alpha-Linolenic acid was incubated with a particulate fraction of homogenate of leaves of the meadow buttercup (Ranunculus acris L.). The main product was a divinyl ether fatty acid, which was identified as 12-[1'(Z),3'(Z)-hexadienyloxy]-9(Z),11(E)-dodecadienoic acid. Addition of glutathione peroxidase and redu...

journal_title：Lipids

authors： Hamberg M

更新日期：1998-11-01 00:00:00

abstract：:Experimental studies have suggested an important role of the spleen in lipid metabolism, although with controversial results. Our purpose was to analyze the effect of a nutritionally balanced (NB) diet and a diet containing pork fat (PF) as source of lipids on the lipid profile of rats submitted to splenic surgery. Si...

journal_title：Lipids

authors： Dinis AP,Marques RG,Simões FC,Diestel CF,Caetano CE,Secchin DJ,Neto JF,Portela MC

更新日期：2009-06-01 00:00:00

abstract：:Several ions in the mass spectra of wax esters were related to the molecular structures. Assigned structures of ions were confirmed by deuterium labeling. A simple, direct method for quantititive analyses of mixtures was developed. The method involved a comparison of sets of three ions, RCO2H(+), RCO2H2 (+) and [R'-1]...

journal_title：Lipids

authors： Aasen AJ,Hofstetter HH,Iyengar BT,Holman RT

更新日期：1971-07-01 00:00:00

abstract：:[3-(14)C] Eicosatrienoic acid (delta11,14,17) chemically synthesized from [-(14)C] linolenic acid was injected intracranially into 14-day old rats and sacrificed 8 hr later. The analysis of brain fatty acids by radio-gas liquid chromatography before and after ozonolysis showed that the tetraene fraction consisted of a...

journal_title：Lipids

authors： Dhopeshiwarkar GA,Subramanian C

更新日期：1976-09-01 00:00:00

abstract：:Human chylomicron triglyceride (TG) kinetics has been difficult to determine directly owing to technical limitations. This report describes a new method for studying chylomicron metabolism. Healthy volunteers (n = 10) sipped a drink providing 175 mg fat x kg(-1) h(-1) for 7.5 h to produce a steady-state chylomicronemi...

journal_title：Lipids

authors： Park Y,Damron BD,Miles JM,Harris WS

更新日期：2001-02-01 00:00:00

abstract：:A protocol using a dry column method was modified for the extraction of total lipids and the simultaneous separation and quantitation of neutral and polar lipids in human milk. The triacylglycerol, cholesterol, phospholipid and vitamin E contents of the lipid extracts were determined and compared with lipids extracted...

journal_title：Lipids

authors： Collins SE,Jackson MB,Lammi-Keefe CJ,Jensen RG

更新日期：1989-08-01 00:00:00

abstract：:The physiological role of long-chain fatty acyl-CoA is thought to be primarily in intermediary metabolism of fatty acids. However, recent data show that nM to microM levels of these lipophilic molecules are potent regulators of cell functions in vitro. Although long-chain fatty acyl-CoA are present at several hundred ...

journal_title：Lipids

authors： Gossett RE,Frolov AA,Roths JB,Behnke WD,Kier AB,Schroeder F

更新日期：1996-09-01 00:00:00

abstract：:Dietary fat intake influences plasma glucose concentration through modifying glucose uptake and utilization by adipose and skeletal muscle tissues. In this paper, we studied the effects of a low-fat diet on diaphragm GLUT4 expression and fatty acid composition in control and streptozotocin-induced diabetic rats. Contr...

journal_title：Lipids

authors： Girón MD,Salto R,Hortelano P,Periago JL,Vargas AM,Suárez MD

更新日期：1999-08-01 00:00:00

abstract：:In experiments with 4 different types of cells, we evaluated the cholesterogenic activity by incorporation of 14C-acetic acid into cholesterol and digitonin-precipitable sterols. In every case, the cholesterogenesis appeared considerably faster when expressed as digitonid than when expressed as real cholesterol produc...

journal_title：Lipids

authors： Tabacik C,Aliau S,Crastes de Paulet A

更新日期：1983-09-01 00:00:00

abstract：:Two simple methods for the synthesis of phosphatidylcholine (lecithin) isotopically labeled in the methyl group of the choline moiety are described. Phosphatidylcholine is converted to phosphatidyl-ethanolamine by enzymic transphosphatidylation, and this is methylated using either methyl iodide or diazomethane to give...

journal_title：Lipids

authors： Smith GA,Montecucco C,Bennett JP

更新日期：1978-01-01 00:00:00

abstract：:During germination of seeds of the gymnosperm, Pinus pinea, radioactivity from [2-14C]-mevalonate proceeded principally through the anaerobic reactions leading to squalene in the first 24 hr in both the haploid endosperm and the diploid embryo, and only with succeeding time (3-9 days) in both cases was label transferr...

journal_title：Lipids

authors： McKean ML,Nes WR

更新日期：1977-04-01 00:00:00

abstract：:The total lipid content, composition of main lipid classes, composition of sterols and composition of fatty acids in the main glycerolipids of Perna viridis were analyzed through four seasons using TLC-FID and GLC. Mussel samples were collected during different seasons between 2003 and 2004 from Shengsi Island, Zhejia...

journal_title：Lipids

authors： Li D,Zhang Y,Sinclair AJ

更新日期：2007-08-01 00:00:00

abstract：:The calcium ionophore A23187 stimulates release of free [3H]arachidonic acids from radiolabeled cultures of MEPM cells which are growing, but not from those which are confluent. However, when confluent MEPM cells are pretreated with EGF or PMA, release of [3H]arachidonic acids does occur in response to A23187. Since n...

journal_title：Lipids

authors： Chepenik KP

更新日期：1989-09-01 00:00:00

abstract：:An effective resolution of intact phosphatidylserines on the basis of unsaturation has been achieved by conventional argentation thin layer chromatography (TLC) following trifluoracetylaction. The trifluoroacetamides are prepared by treatment with trifluoroacetic anhydride or N-methyl-bis-trifluoroacetamide. The aceta...

journal_title：Lipids

authors： Yeung SK,Kuksis A,Marai L,Myher JJ

更新日期：1977-07-01 00:00:00

abstract：:This study was designed to determine the nutritional lipid requirement of Manchurian trout and to investigate the effects of lipid concentrations on the antioxidant status in larvae with experimental diets with different lipid levels. Oxidative stress differences between different organs and tissues were also assessed...

journal_title：Lipids

authors： Zhang H,Mu Z,Xu L,Xu G,Liu M,Shan A

更新日期：2009-07-01 00:00:00

abstract：:The triacylglycerols of very low density lipoproteins (VLDL-TG) were analyzed in samples from normal subjects and patients with Frederickson's Type III and Type IV hyperlipoproteinemia. VLDL were obtained by conventional ultracentrifugation, and the triacylglycerols were isolated by thin-layer chromatography (TLC). Re...

journal_title：Lipids

authors： Myher JJ,Kuksis A,Breckenridge WC,Little JA

更新日期：1984-09-01 00:00:00

abstract：:This study investigated a possible role for the epidermal growth factor (EGF) receptor protein tyrosine kinase in phosphoinositide metabolism with plasma membrane vesicles from human epidermoid carcinoma (A431) cells. We found a novel chloroform-soluble product radiolabeled with [gamma-32P]ATP that did not migrate fro...

journal_title：Lipids

authors： Brautigan DL,Randazzo P,Shriner C,Fain JN

更新日期：1985-07-01 00:00:00

abstract：:The particular interest in supplementing human foods with n-3 fatty acids has arisen from the findings that this series of polyunsaturated fatty acids (PUFA) have an impact on neuronal functions. Indeed vertebrates, including humans, preferentially use docosahexaenoic acid (DHA, 22:6n-3) over other long-chain n-3 PUFA...

journal_title：Lipids

authors： Pifferi F,Perret M,Guesnet P,Aujard F,Alessandri JM

更新日期：2012-08-01 00:00:00

abstract：:The suppression of plasma very low density lipoprotein (VLDL) triglyceride levels by dietary fish oils rich in polyunsaturated n-3 fatty acids has been attributed to decreased hepatic VLDL secretion. To investigate the effect of n-3 fatty acids on lipid metabolism and VLDL secretion in a tissue culture system, we incu...

journal_title：Lipids

authors： Benner KG,Sasaki A,Gowen DR,Weaver A,Connor WE

更新日期：1990-09-01 00:00:00

abstract：:Seventy-two surgically obtained Dupuytren's disease palmar-fat (DDPF) specimens and 18 location-matched specimens from patients not suffering from this disease (controls) were studied for their total lipid composition and de novo lipogenic activity. Incubation of "DDPF" with 1-[14C]acetate in oxygen produced [14C]palm...

journal_title：Lipids

authors： Rabinowitz JL,Ostermann L Jr,Bora FW,Staeffen J

更新日期：1983-05-01 00:00:00

abstract：:Trilinoleoylglycerol (LLL), trilinolenoylglycerol (LnLnLn) and four synthetic triacylglycerols were autoxidized and the volatile products were investigated to determine the effect of fatty acid glyceride position on the mechanism of hydroperoxide decomposition. Capillary gas chromatography provided a sensitive method ...

journal_title：Lipids

authors： Frankel EN,Selke E,Neff WE,Miyashita K

更新日期：1992-06-01 00:00:00

abstract：:The aim of the present study was to characterize plasma lipids and lipoprotein cholesterol and glucose concentrations in hamsters fed either cis-9,trans-11 CLA (9c,11 tCLA); trans-10,cis-12 CLA (10t,12c CLA); or linoleic acid (LA) on the accumulation of aortic cholesterol in hypercholesterolemic hamsters. One hundred ...

journal_title：Lipids

authors： Wilson TA,Nicolosi RJ,Saati A,Kotyla T,Kritchevsky D

更新日期：2006-01-01 00:00:00

abstract：:Trans FA (TFA) have at least one trans double bond and comprise several isomers and types, including many of the CLA (e.g., c9,t11-18:2 CLA). Some TFA may have adverse effects (e.g., cardiovascular disease), whereas some are thought to have beneficial effects (e.g., anticarcinogenicity). The presence of TFA in human t...

journal_title：Lipids

authors： Shahin AM,McGuire MK,Anderson N,Williams J,McGuire MA

更新日期：2006-02-01 00:00:00

abstract：:The effect of phosphatidylserine and sterol carrier proteins on cholesterol exchange was determined using an assay not requiring separation of donor and acceptor membrane vesicles. Sterol carrier protein-2 (SCP2, also called nonspecific lipid transfer protein), but not fatty acid binding protein (FABP, also called ste...

journal_title：Lipids

authors： Schroeder F,Butko P,Hapala I,Scallen TJ

更新日期：1990-11-01 00:00:00

abstract：:Steroids bearing ketone functionality at carbon-7 are found commonly in nature, and the most prevalent of these are the 7-keto-delta5-sterols. These substances have diverse biological properties and are present in biological samples and food products. For the purpose of studying this class of oxysterols, many chemical...

journal_title：Lipids

authors： Parish EJ,Kizito SA,Qiu Z

更新日期：2004-08-01 00:00:00

abstract：:The farnesoid X receptor (FXR, NR1H4) has been recognized as an attractive therapeutic target because it is a nuclear hormone receptor that controls the expression level of cholesterol-7alpha-hydroxylase, which in turn regulates bile acid production and cholesterol excretion. To compare receptor activity between each ...

journal_title：Lipids

authors： Cho KH,Park JY,Han JI,Jeong TS

更新日期：2003-11-01 00:00:00