Biosynthesis of polyunsaturated fatty acids in the developing brain: II. Metabolic transformations of intracranially administered [3-(14)C] Eicosatrienoic acid, evidence for lack of delta8 desaturase.

abstract：:The catfish, Ictalurus punctatus, is an important model for studying the biochemical mechanisms of taste at the peripheral level. The type, amount and metabolic activity of the lipids within this tissue play important roles in taste transduction by forming the matrix in which the receptors for taste stimuli are imbedd...

journal_title：Lipids

authors： Rabinowitz JL,Huque T,Brand JG,Bayley DL

更新日期：1990-04-01 00:00:00

abstract：:The contractions of three different regions of rat colon in response to platelet-activating factor (PAF) were compared. The ascending colon was found to be the most responsive. The slow contraction of the ascending colon induced by PAF was dependent on external Ca2+. CV-3988, a structural analog of PAF, slowly induced...

journal_title：Lipids

authors： Tokumura A,Yube N,Terao M,Tsukatani H

更新日期：1991-12-01 00:00:00

abstract：:Electron paramagnetic resonance (EPR) in conjunction with a slow-tumbling simulation was utilized for defining stratum corneum (SC) lipid structure. SC from the back of hairless mouse (HOS:HR-1) was stripped consecutively from one to three or four times using a glass plate coated with a cyanoacrylate resin. Aliphatic ...

journal_title：Lipids

authors： Nakagawa K,Anzai K

更新日期：2010-11-01 00:00:00

abstract：:The anesthetic potency of four derivatives of n-octane was measured by tadpole righting reflex and expressed as effective millimolar concentration of drug in membrane, EDM50. Potency diminished (ED50 increased) in this order: 1-octanol, EDM50 = 5.5; 1-(2-methoxyethoxy)octane, EDM50 = 28; 1-methoxyoctane, EDM50 = 61; a...

journal_title：Lipids

authors： Brockerhoff H,Brockerhoff S,Box LL

更新日期：1986-06-01 00:00:00

abstract：:In this study, we investigated the effect of various types of fats on heart lipid peroxidation status and on blood lipid parameters. Rats were fed either a low-fat diet (2.2% lard plus 2.2% corn oil), a corn oil diet (17%), a salmon oil diet (12.5%) supplemented with 4.5% corn oil, or a lard diet (15%) supplemented wi...

journal_title：Lipids

authors： Nalbone G,Leonardi J,Termine E,Portugal H,Lechene P,Pauli AM,Lafont H

更新日期：1989-03-01 00:00:00

abstract：:After administering the equivalent of 1 g of eicosapentaenoic acid (EPA) in four different chemical forms, the kinetics of EPA incorporation into plasma triglycerides (TG) were compared by gas liquid chromatography on a capillary column following separation of the lipid fraction by thin layer chromatography. EPA incor...

journal_title：Lipids

authors： el Boustani S,Colette C,Monnier L,Descomps B,Crastes de Paulet A,Mendy F

更新日期：1987-10-01 00:00:00

abstract：:An unidentified bacterial strain, SCRC-21406, isolated from the intestine of a marine fish, Glossanodon semifasciatus, produced docosahexaenoic acid at 23% (mol/mol) [= 28% (w/w)] of total fatty acids in a medium containing 0.5% (wt/vol) peptone and 0.1% (wt/vol) yeast extract at 12 degrees C under atmospheric pressur...

journal_title：Lipids

authors： Watanabe K,Ishikawa C,Ohtsuka I,Kamata M,Tomita M,Yazawa K,Muramatsu H

更新日期：1997-09-01 00:00:00

abstract：:In guinea pigs, total plasma cholesterol concentrations increased above the control values after single intravenous injections and after 3 days of continuous subcutaneous administration of neurotensin (NT). A high dose of NT (125 pmol/100 g body weight) induced tachycardia and severe respiratory distress; the lowest d...

journal_title：Lipids

authors： Peric-Golia L,Gardner CF,Wilson DE,Peric-Golia M

更新日期：1984-10-01 00:00:00

abstract：:Groups of C57Bl/6J mice, fed either a cis (C-Diet) or trans diet (T-Diet) were milked without preconditioning at 6, 8, 10 and 12 days postpartum. On day 10, groups of mice were also milked 4, 6 and 18 h after separation of the pups. Except for the 18-h separation, all T-Diet fed animals produced milk of lower fat cont...

journal_title：Lipids

authors： Teter BB,Sampugna J,Keeney M

更新日期：1992-11-01 00:00:00

abstract：:In order to further characterize low density lipoprotein (LDL)-platelet interaction, we investigated the effect of protease pretreatment of human platelets on the subsequent binding of iodinated LDL (125I-LDL). Our results showed that the platelet LDL receptor had a proteolytic susceptibility different from that of bo...

journal_title：Lipids

authors： Pedreño J,Fernández R

更新日期：1995-10-01 00:00:00

abstract：:Interest in malondialdehyde (MDA) metabolism stems from its formation as a product of lipid peroxidation in the diet and in the tissues; its reactivity with functional groups of nucleic acid bases, proteins and phospholipids; its mutagenicity in bacteria, and its reported skin and liver carcinogenicity in animals. Adm...

journal_title：Lipids

authors： Draper HH,McGirr LG,Hadley M

更新日期：1986-04-01 00:00:00

abstract：:Plasma fatty acid (FA) composition is known to be an indicator of dietary fat quality, but the associations of other dietary factors with plasma FA composition remain unknown in children. We investigated the cross-sectional associations of food consumption with the proportions of FA and estimated desaturase activities...

journal_title：Lipids

authors： Venäläinen T,Schwab U,Ågren J,de Mello V,Lindi V,Eloranta AM,Kiiskinen S,Laaksonen D,Lakka TA

更新日期：2014-05-01 00:00:00

abstract：:A novel phospholipid containing a chromanol structure at its polar head group was synthesized from egg yolk phosphatidylcholine and 2,5,7,8-tetramethyl-6-hydroxy-2-(hydroxyethyl)chroman by transphosphatidylation catalyzed by phospholipase D from Streptomyces lydicus. The structure of the product synthesized was shown ...

journal_title：Lipids

authors： Koga T,Nagao A,Terao J,Sawada K,Mukai K

更新日期：1994-02-01 00:00:00

abstract：:The contents and compositions of the 1-O-alk-1'-enyl-2-acyl, 1-O-alkyl-2-acyl, and 1,2-diacyl glycerophospholipids in the muscle and viscera of the ascidian Halocynthia roretzi, and of the gonad of the sea urchin Strongylocentrotus intermedius, which are eaten to some extent in Alaska and in Asia, were analyzed by gas...

journal_title：Lipids

authors： Jeong BY,Ohshima T,Koizumi C

更新日期：1996-01-01 00:00:00

abstract：:Sterols, which are biosynthesized via the cytoplasmic mevalonate (MVA) pathway, are important structural components of the plasma membrane and precursors of steroid hormones in both vertebrates and plants. Ergosterol and cholesterol are the major sterols in yeast and vertebrates, respectively. In contrast, plants prod...

journal_title：Lipids

authors： Suzuki M,Muranaka T

更新日期：2007-02-01 00:00:00

abstract：:Cholesterol biosynthesis from acetate-2-(14)C by the livers of suckling rats, which is known to be relatively slow, was increased 2-3-fold within 24 hours after severing the bile duct. Cholesterol synthesis by sham-operated litter mates showed no change under similar treatment. Mevalonate biosynthesis from acetate-2-(...

journal_title：Lipids

authors： Harris RA,Rivera ER,Villemez CL Jr,Quackenbush FW

更新日期：1967-03-01 00:00:00

abstract：:The particular interest in supplementing human foods with n-3 fatty acids has arisen from the findings that this series of polyunsaturated fatty acids (PUFA) have an impact on neuronal functions. Indeed vertebrates, including humans, preferentially use docosahexaenoic acid (DHA, 22:6n-3) over other long-chain n-3 PUFA...

journal_title：Lipids

authors： Pifferi F,Perret M,Guesnet P,Aujard F,Alessandri JM

更新日期：2012-08-01 00:00:00

abstract：:Saturated fatty acids are the most abundant fatty acids in the brain, however, there has been some debate regarding the ability of intact dietary saturated fatty acids to be incorporated into the brain. In the present study, we use compound specific isotope analysis to measure the natural abundance carbon isotopic sig...

journal_title：Lipids

authors： Lacombe RJS,Giuliano V,Chouinard-Watkins R,Bazinet RP

更新日期：2018-05-01 00:00:00

abstract：:Taurolithocholic acid and deoxycholic acid were perfused into isolated prairie dog livers. Taurolithocholic acid was 7 alpha-hydroxylated to form taurochenodeoxycholic acid, whereas deoxycholic acid was conjugated and 7 alpha-hydroxylated to form taurocholic acid. The low concentrations of secondary bile acids observe...

journal_title：Lipids

authors： Cohen BI,Singhal AK,Mongelli J,Rothschild MA,McSherry CK,Mosbach EH

更新日期：1983-12-01 00:00:00

abstract：:The presence of leptin receptors in white adipose tissue (WAT) suggests a type of peripheral control during the development of obesity and other metabolic disorders. Both diet composition and exercise influence serum leptin; however, the effect of their combination on long-term WAT leptin metabolism is unknown. In thi...

journal_title：Lipids

authors： de Queiroz KB,Guimarães JB,Coimbra CC,Rodovalho GV,Carneiro CM,Evangelista EA,Guerra-Sá R

更新日期：2014-01-01 00:00:00

abstract：:Previous reports have suggested that cargo-free cationic nanoparticles (cNP) consisting of cationic monovalent lipids, such as 1,2-oleoyl-3-trimethylammonium-propane (DOTAP), induce reactive oxygen species (ROS) generation and toxicity in cells. In addition, cNP containing six lysine residues (6K) and cargo (6K-cNP) e...

journal_title：Lipids

authors： Bae CS,Ahn T

更新日期：2018-11-01 00:00:00

abstract：:The purpose of this study was to examine the influence of long-term feeding of dietary fat rich in either n-3 or n-6 fatty acids on the availability of arachidonic acid (20:4n-6) in major phospholipids of gastric mucosa in rats. Three groups of male Wistar rats were fed either a standard diet, a cod liver oil-enriched...

journal_title：Lipids

authors： Olafsson SO,Hallgrimsson J,Gudbjarnason S

更新日期：2000-06-01 00:00:00

abstract：:The acylation of lysophospholipids by rat liver acyltransferases was studied. A comparison between ester and ether lysophospholipids as substrates revealed large differences in substrate properties. For instance, oleic acid from oleoyl-CoA and arachidonic acid from arachidonoyl-CoA were not incorporated into 1-O-octad...

journal_title：Lipids

authors： Neumüller W,Fleer EA,Unger C,Eibl H

更新日期：1987-11-01 00:00:00

abstract：:Separation of thecis- andtrans-isomers of 1,2-benzylidene glyceryl esters has not yet been achieved by column or gas liquid chromatography. However these isomers were separated by thin layer chromatography in the present study and the parent cyclic alcohols regenerated by alkaline hydrolysis. ...

journal_title：Lipids

authors： Johnson CB

更新日期：1973-08-01 00:00:00

abstract：:A simple and sensitive method to analyze mixtures of desmosterol, 7-dehydrocholesterol and cholesterol is described. The method involves the oxidative conversion of the sterols with cholesterol oxidase, followed by high performance liquid chromatographic (HPLC) analysis. A C18 reversed phase column (3 microns, 75 X 4....

journal_title：Lipids

authors： Goh EH,Colles SM,Otte KD

更新日期：1989-07-01 00:00:00

abstract：:The synthesis of thioether phospholipids, which represent a new class of antitumor agents, is reported here. In particular, the route of synthesis of 3-hexadecylmercapto-2-methoxymethylpropyl-2'-trimethylammoni o-ethyl phosphate (BM 41.440, Ilmofosine), one of the most potent cytostatic/cytotoxic derivatives, is descr...

journal_title：Lipids

authors： Bosies E,Herrmann DB,Bicker U,Gall R,Pahlke W

更新日期：1987-11-01 00:00:00

abstract：:Subjects with echolucent carotid plaques have an increased risk of ischemic cerebrovascular events independent of degree of stenosis. Low plasma lipoprotein lipase (LPL) activity promotes a proatherogenic lipid profile, and delayed chylomicron clearance is a risk factor for atherosclerosis. This study was conducted to...

journal_title：Lipids

authors： Notø AT,Mathiesen EB,Brox J,Björkegren J,Hansen JB

更新日期：2008-04-01 00:00:00

abstract：:The eicosapentaenoic acid (EPA) synthesis gene cluster from an EPA-producing bacterium, Shewanella sp. SCRC-2738, was cloned into a broad-host range vector, pJRD215, and then introduced into a marine cyanobacterium, Synechococcus sp. NKBG15041c, by conjugation. The transconjugant cyanobacteria produced 3.7 +/- 0.2% (2...

journal_title：Lipids

authors： Yu R,Yamada A,Watanabe K,Yazawa K,Takeyama H,Matsunaga T,Kurane R

更新日期：2000-10-01 00:00:00

abstract：:Facile procedures are described for nearly quantitative conversion of saturated and unsaturated fatty aldehydes to their dimethyl acetals, and vice versa, at low temperatures. The methods are based on the chemical behavior of aldehydes and dimethyl acetals in 100% sulfuric acid. Under the experimental conditions descr...

journal_title：Lipids

authors： Mahadevan V,Viswanathan CV,Lundberg WO

更新日期：1966-09-01 00:00:00

abstract：:Total lipids from whole pig adrenal glands as well as from their mitochondria, microsomes, liposomes, and cell sap were extracted and fractionated first into neutral lipids and phospholipids. The highest percentage of neutral lipids was found in the cell sap, and the lowest in the microsomal fraction. Neutral lipids w...

journal_title：Lipids

authors： Cmelik SH,Ley H

更新日期：1975-11-01 00:00:00