Enteral absorption in man of eicosapentaenoic acid in different chemical forms.

Abstract:

:After administering the equivalent of 1 g of eicosapentaenoic acid (EPA) in four different chemical forms, the kinetics of EPA incorporation into plasma triglycerides (TG) were compared by gas liquid chromatography on a capillary column following separation of the lipid fraction by thin layer chromatography. EPA incorporation into plasma TG was markedly smaller and later when EPA was administered as an ethyl ester rather than as EPA free fatty acid, EPA arginine salt or 1,3-dioctanoyl-2-eicosapentaenoyl glycerol (2-EPA). Our results and the data in the literature are compatible with the hypothesis that 2-EPA is absorbed with minimum hydrolysis and escapes random distribution between the other positions of the glycerol molecule during the absorption process.

journal_name

Lipids

journal_title

Lipids

authors

el Boustani S,Colette C,Monnier L,Descomps B,Crastes de Paulet A,Mendy F

doi

10.1007/BF02533970

subject

Has Abstract

pub_date

1987-10-01 00:00:00

pages

711-4

issue

10

eissn

0024-4201

issn

1558-9307

journal_volume

22

pub_type

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