Activation of acyl-CoA cholesterol acyltransferase: redistribution in microsomal fragments of cholesterol and its facilitated movement by methyl-beta-cyclodextrin.

abstract：:Neuronal membranes are highly enriched with docosahexaenoic acid (22:6n-3), and its content can be altered by ethanol consumption. We have previously reported that the 22:6n-3 status in membrane affects the biosynthesis of phosphatidylserine (PS), a phospholipid class which contains an exceptionally high proportion of...

journal_title：Lipids

authors： Kim HY,Hamilton J

更新日期：2000-02-01 00:00:00

abstract：:The beta-adrenergic system in cardiac muscle cells is influenced by the n-3 polyunsaturated fatty acid (PUFA) content in cell membranes. This study deals with the specific effect of docosahexaenoic acid (DHA) as compared to other n-3 PUFA, without modification of the arachidonic acid content. Increasing the DHA conten...

journal_title：Lipids

authors： Grynberg A,Fournier A,Sergiel JP,Athias P

更新日期：1996-03-01 00:00:00

abstract：:In this paper, evidence is presented on the capacity of Ehrlich ascites cells to synthesize in vitro monounsaturated fatty acids from radioactive palmitate. Localization of the double bond was determined by ozonolysis and subsequent reduction of the ozonides to aldesters followed by gas liquid chromatography. These re...

journal_title：Lipids

authors： Mercuri O,De Tomás ME,de Antueno RJ

更新日期：1981-12-01 00:00:00

abstract：:The artificial rearing model was used to investigate the effects of short-term exposure to ethanol on growth and fatty acid composition of forebrain (FB) and cerebellum (CB) during the brain growth spurt in either n-3 fatty acid-adequate (AD) or n-3 deficient (DEF) rat pups. On postnatal day 5, offspring of female rat...

journal_title：Lipids

authors： Ward GR,Xing HC,Wainwright PE

更新日期：1999-11-01 00:00:00

abstract：:The suppression of plasma very low density lipoprotein (VLDL) triglyceride levels by dietary fish oils rich in polyunsaturated n-3 fatty acids has been attributed to decreased hepatic VLDL secretion. To investigate the effect of n-3 fatty acids on lipid metabolism and VLDL secretion in a tissue culture system, we incu...

journal_title：Lipids

authors： Benner KG,Sasaki A,Gowen DR,Weaver A,Connor WE

更新日期：1990-09-01 00:00:00

abstract：:Intact washed human platelets aggregated in response to paf-acether (paf) and did not metabolize [3H]paf at concentrations up to 10 nM. However, when platelets were lysed by exposure to pH 9.5, resulting in 37.5 +/- 2.5% (mean +/- SD, n = 3) lactic dehydrogenase (LDH) release, 20.5 +/- 5.7% of the radioactivity was de...

journal_title：Lipids

authors： Korth R,Bidault J,Palmantier R,Benveniste J,Ninio E

更新日期：1993-03-01 00:00:00

abstract：:Levels of serum lipids and lipoproteins, and the fatty acid composition of plasma phospholipids, were measured in two genetically comparable, but widely separated, populations. The 1975 mortality rates for ischemic heart disease were significantly higher in one of these populations, the Manitoban residents of pure Ice...

journal_title：Lipids

authors： Skúladóttir GV,Gudmundsdóttir S,Olafsson GB,Sigurdsson SB,Sigfússon N,Axelsson J

更新日期：1995-07-01 00:00:00

abstract：:Greatly increasing the amounts of flaxseed oil [rich in alpha-linolenic acid (ALNA)] or fish oil (FO); [rich in eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA)] in the diet can decrease inflammatory cell functions and so might impair host defense. The objective of this study was to determine the effect of d...

journal_title：Lipids

authors： Thies F,Miles EA,Nebe-von-Caron G,Powell JR,Hurst TL,Newsholme EA,Calder PC

更新日期：2001-11-01 00:00:00

abstract：:The amount of docosahexaenoate (22:6n-3)-containing phospholipid species decreases with aging in the rat retina. Most lipids, but especially choline and serine glycerophospholipids, show a significant fall in 22:6n-3, which is not compensated by increases in other polyenoic fatty acids. The decrease not only affects 2...

journal_title：Lipids

authors： Rotstein NP,Ilincheta de Boschero MG,Giusto NM,Aveldaño MI

更新日期：1987-04-01 00:00:00

abstract：:In plants, two pathways are utilized for the synthesis of isopentenyl diphosphate (IPP), the universal precursor for isoprenoid biosynthesis. In this paper we review findings and observations made primarily with tobacco BY-2 cells (TBY-2), which have proven to be an excellent system in which to study the two biosynthe...

journal_title：Lipids

authors： Hemmerlin A,Gerber E,Feldtrauer JF,Wentzinger L,Hartmann MA,Tritsch D,Hoeffler JF,Rohmer M,Bach TJ

更新日期：2004-08-01 00:00:00

abstract：:Male Wistar rats were fed semipurifed diets containing 20% fat for 25 weeks. Ten different oils or oil blends were employed, including rapessed oils, simulated rapeseed-type oils, and modified rapeseed-type oils. Safflower, soybean, and hydrogenated coconut oils served as control oils. Histopathological examination of...

journal_title：Lipids

authors： McCutcheon JS,Umermura T,Bhatnager MK,Walker BL

更新日期：1976-07-01 00:00:00

abstract：:Fish easily accumulate n-3 PUFA of exogenous origin, but the underlying mechanisms are not well established in the whole animal. This study was undertaken to investigate whether this feature was physiologically associated with mitochondrial and peroxisomal capacities that differentially affect FA oxidation. For this p...

journal_title：Lipids

authors： Du ZY,Demizieux L,Degrace P,Gresti J,Moindrot B,Liu YJ,Tian LX,Cao JM,Clouet P

更新日期：2004-09-01 00:00:00

abstract：:In the wild, nutrients from plants provide for the requirements of all herbivores and ultimately all animals, yet little work has been published on how such nutrients change with environmental conditions. Plant lipids are nutritionally important for browsing mammals, initially with respect to taste and palatability, b...

journal_title：Lipids

authors： Davidson BC

更新日期：1998-01-01 00:00:00

abstract：:A new method of isoelectric focusing (IEF) and pH gradient electrophoresis, using thin layers of agarose gel beads, was devised to investigate chylomicrons and very low density lipoproteins (VLDL). pH gradient stability and cathodal gradient drift were similar to those of polyacrylamide gel IEF, and linearity of gradi...

journal_title：Lipids

authors： Vost A,Pocock DM,Pleet S

更新日期：1979-10-01 00:00:00

abstract：:Male weanling rats were fed semi-synthetic diets high in saturated fat (beef tallow) vs high in linoleic acid (safflower oil) with or without high levels of alpha-linolenic acid (linseed oil) for a period of 28 days. The effect of feeding these diets on cholesterol content and fatty acid composition of serum and liver...

journal_title：Lipids

authors： Garg ML,Wierzbicki AA,Thomson AB,Clandinin MT

更新日期：1989-04-01 00:00:00

abstract：:Several ions in the mass spectra of wax esters were related to the molecular structures. Assigned structures of ions were confirmed by deuterium labeling. A simple, direct method for quantititive analyses of mixtures was developed. The method involved a comparison of sets of three ions, RCO2H(+), RCO2H2 (+) and [R'-1]...

journal_title：Lipids

authors： Aasen AJ,Hofstetter HH,Iyengar BT,Holman RT

更新日期：1971-07-01 00:00:00

abstract：:Soy isoflavones may impede atherogenic processes associated with cardiovascular disease. Research suggests that the postprandial generation of TG-rich remnants contributes to the development of atherosclerosis. The purpose of the current study was to determine if 39 g soy (85 mg aglycone isoflavones, treatment) compar...

journal_title：Lipids

authors： Campbell CG,Brown BD,Dufner D,Thorland WG

更新日期：2006-03-01 00:00:00

abstract：:The sn-position of FA in membrane lipids has an influence on the physiological function of cells, is predictive for diseases, and therefore is useful for diagnostics. The current study compares the compositions of acyl chain substituents in the sn-1 and sn-2 positions of the glycerol backbones of phospholipids derived...

journal_title：Lipids

authors： Beermann C,Möbius M,Winterling N,Schmitt JJ,Boehm G

更新日期：2005-02-01 00:00:00

abstract：:Studies investigated the effects of dietary fatty acid composition and saturation on the regulation of very low density lipoprotein (VLDL) apo B flux, clearance, and conversion to low density lipoprotein (LDL) in guinea pigs fed semipurified diets containing 15% (w/w) corn oil (CO), lard (LA), or palm kernel oil (PK)....

journal_title：Lipids

authors： Abdel-Fattah G,Fernandez ML,McNamara DJ

更新日期：1998-01-01 00:00:00

abstract：:The current state of knowledge concerning the absorption and transport of dietary fat with emphasis on long-chain polyunsaturated n-3 fatty acids in mammals is reviewed. It is apparent that long-chain polyunsaturated n-3 fatty acids, either as free acids or as part of triglycerides, are readily absorbed in the gut and...

journal_title：Lipids

authors： Nelson GJ,Ackman RG

更新日期：1988-11-01 00:00:00

abstract：:Normal phase high performance liquid chromatography methods are described for the separation of neutral lipid, fatty acid and five phospholipid classes using spectrophotometric detection at 206 nm. Separations were accomplished in less than 10 min for each lipid class. A mobile phase consisting of hexane/methyltertiar...

journal_title：Lipids

authors： Hamilton JG,Comai K

更新日期：1988-12-01 00:00:00

abstract：:Mitochondrial cytochrome P450 enzymes (CYP or P450, EC 1.14.13.15) play an important role in metabolism of cholesterol. CYP27A1 hydroxylates cholesterol at position 27 and, thus, initiates cholesterol removal from many extrahepatic tissues. CYP11A1 is a steroidogenic P450 that converts cholesterol to pregnenolone, the...

journal_title：Lipids

authors： Pikuleva IA,Mast N,Liao WL,Turko IV

更新日期：2008-12-01 00:00:00

abstract：:In the present study we evaluated the uptake of ALA and its conversion to EPA + DHA in rats given linseed oil (LSO) in native form or as a microemulsion in whey protein or in lipoid. In a single oral dose study in which rats maintained on rodent pellets deficient in ω-3 fatty acids were intubated with 0.35 g LSO in li...

journal_title：Lipids

authors： Sugasini D,Devaraj VC,Ramesh M,Lokesh BR

更新日期：2014-03-01 00:00:00

abstract：:The burrowing sponges Anthosigmella varians and Spheciospongia vesparium were found to be rich in the isoprenoid phospholipid fatty acid 4,8,12-trimethyltridecanoic (5.2% and 23%, respectively, of the total fatty acid composition), while the burrowing sponge Chondrilla nucula and the demosponge Agelas dispar contained...

journal_title：Lipids

authors： Carballeira NM,Maldonado L,Porras B

更新日期：1987-10-01 00:00:00

abstract：:Microsomal and myelin membrane fractions were prepared from the brains of warm-adapted (room temperature) and hibernating Syrian Hamsters (Mesocricetus auratus). Ethanolamineglycerophospholipids were isolated and subjected to a fractionation scheme to separate the fatty acids of the plasmenylethanolamine and the phosp...

journal_title：Lipids

authors： Blaker WD,Moscatelli EA

更新日期：1979-12-01 00:00:00

abstract：:Milk fatty acids consist of about 20-25% palmitic acid (16:0), with about 70% of 16:0 esterified to the sn-2 position of the milk triacylglycerols. Hydrolysis of dietary triacylglycerols by endogeneous lipases produces sn-2 monoacylglycerols and free fatty acids, which are absorbed, reesterified, and then secreted int...

journal_title：Lipids

authors： Innis SM,Dyer R,Nelson CM

更新日期：1994-08-01 00:00:00

abstract：:The Ca and Mg content of flax and corn phosphatidyl inositol fractions has been determined. Procedures were devised to prepare various salt forms of phosphatidyl inositol. The divalent cations were exchanged for monovalent ions (Na or K) on chelating resin columns. With the Folch wash procedure the Na or K forms of ph...

journal_title：Lipids

authors： Carter HE,Weber EJ

更新日期：1966-01-01 00:00:00

abstract：:The fatty acid (FA) profile of oysters generally reflects the dietary FA composition. Moreover, incorporation of FA into tissues is modulated by various metabolic factors, and final composition will depend upon the dietary sources, cumulative intake, and oysters' development stage. Thus, the aim of this study was to a...

journal_title：Lipids

authors： Rato A,Pereira LF,Joaquim S,Gomes R,Afonso C,Cardoso C,Machado J,Gonçalves JFM,Vaz-Pires P,Magnoni LJ,Matias AM,Matias D,Bandarra NM,Ozório ROA

更新日期：2019-09-01 00:00:00

abstract：:All fatty acids have important functions, but the term "essential" is applied only to those polyunsaturated fatty acids (PUFA) that are necessary for good health and cannot be completely synthesized in the body. The need for arachidonic acid, which is utilized for eicosanoid synthesis and is a constituent of membrane ...

journal_title：Lipids

authors： Spector AA

更新日期：1999-01-01 00:00:00

abstract：:The particular interest in supplementing human foods with n-3 fatty acids has arisen from the findings that this series of polyunsaturated fatty acids (PUFA) have an impact on neuronal functions. Indeed vertebrates, including humans, preferentially use docosahexaenoic acid (DHA, 22:6n-3) over other long-chain n-3 PUFA...

journal_title：Lipids

authors： Pifferi F,Perret M,Guesnet P,Aujard F,Alessandri JM

更新日期：2012-08-01 00:00:00