Accumulation of docosahexaenoic acid in phosphatidylserine is selectively inhibited by chronic ethanol exposure in C-6 glioma cells.

abstract：:Previous studies from our laboratory have shown that retinitis pigmentosa (RP), a family of hereditary retinal degenerations, is often accompanied by abnormal levels of cholesterol or polyunsaturated fatty acids. The requirement of the retina for n-3 fatty acids is well known, and a defect in the supply of these lipid...

journal_title：Lipids

authors： Huq L,McLachlan T,Hammer HM,Bedford D,Packard CJ,Shepherd J,Converse CA

更新日期：1993-11-01 00:00:00

abstract：:Glucose-sensitive liposomes were prepared by incorporating hydrophobically modified glucose oxidase (EC 1.1.3.4.) into the liposomal bilayer of dioleoylphosphatidylethanolamine and cholesteryl hemisuccinate. For the release test, calcein, a fluorescence marker, was entrapped in the liposomes. The liposomes were stable...

journal_title：Lipids

authors： Jo SM,Lee HY,Kim JC

更新日期：2008-10-01 00:00:00

abstract：:Factors involved in reduced glutathione (GSH) and vitamin E-mediated inhibition of NADPH-dependent rat liver microsomal lipid peroxidation were examined. Lipid peroxidation was monitored over a time-course of 180 min by thiobarbituric acid reactive product formation. The addition of 5 mM GSH to the reaction system con...

journal_title：Lipids

authors： Graham KS,Reddy CC,Scholz RW

更新日期：1989-11-01 00:00:00

abstract：:Lipophilic toxins have been introduced into the environment both as functional compounds, such as pesticides, and as industrial waste from incineration or the manufacture of electrical transformer components. Among these substances are compounds that are carcinogenic and that affect the endocrine system. Accidental hi...

journal_title：Lipids

authors： Jandacek RJ,Tso P

更新日期：2001-12-01 00:00:00

abstract：:CLA mixtures are now commercially available. They differ from each other with respect to their content of CLA isomers and their degree of purification. As a group of natural FA, CLA have been widely assumed to be safe. However, the suspected presence of both impurities and particular isomers might induce undesirable s...

journal_title：Lipids

authors： Gaullier JM,Berven G,Blankson H,Gudmundsen O

更新日期：2002-11-01 00:00:00

abstract：:The aim of the present study was to develop a cell culture system for studying the proliferation and differentiation of preadipocytes isolated from Atlantic salmon adipose tissue. The expression of proliferating cell nuclear antigen (PCNA) was used as a marker for cell proliferation. The cells started to proliferate w...

journal_title：Lipids

authors： Vegusdal A,Sundvold H,Gjøen T,Ruyter B

更新日期：2003-03-01 00:00:00

abstract：:Epoxidation of the double bond in methyl oleate, octadec-11E-en-9-ynoate, ricinoleate (12-hydroxy-octadec-9Z-enoate), iso-ricinoleate (9-hydroxy-octadec-12Z-enoate), and 12-oxo-octadec-9Z-enoate with potassium peroxomonosulfate (oxone, 2 KHSO5.KHSO4.K2SO4) in the presence of trifluoroacetone or methyl pyruvate gave th...

journal_title：Lipids

authors： Lie Ken Jie MS,Pasha MK

更新日期：1998-06-01 00:00:00

abstract：:A maternal high fat diet (HFD) can have adverse effects on skeletal muscle development. Skeletal muscle PLIN proteins (PLIN2, 3 and 5) are thought to play critical roles in lipid metabolism, however effects of HFD on PLIN and lipases (HSL, ATGL, CGI-58) in mothers as well as their offspring have yet to be investigated...

journal_title：Lipids

authors： MacPherson RE,Castelli LM,Miotto PM,Frendo-Cumbo S,Milburn A,Roy BD,LeBlanc PJ,Ward WE,Peters SJ

更新日期：2015-02-01 00:00:00

abstract：:Bioassay-guided fractionation of a collection of Moorea bouillonii from Papua New Guinea led to the isolation of a new alkyl amide, mooreamide A (1), along with the cytotoxic apratoxins A-C and E. The planar structure of 1 was elucidated by NMR spectroscopy and mass spectrometry analysis. Structural homology between m...

journal_title：Lipids

authors： Mevers E,Matainaho T,Allara' M,Di Marzo V,Gerwick WH

更新日期：2014-11-01 00:00:00

abstract：:The sn-position of FA in membrane lipids has an influence on the physiological function of cells, is predictive for diseases, and therefore is useful for diagnostics. The current study compares the compositions of acyl chain substituents in the sn-1 and sn-2 positions of the glycerol backbones of phospholipids derived...

journal_title：Lipids

authors： Beermann C,Möbius M,Winterling N,Schmitt JJ,Boehm G

更新日期：2005-02-01 00:00:00

abstract：:This study reports the cloning, functional characterization, tissue expression, and nutritional regulation of a delta6 fatty acyl desaturase of Atlantic cod (Gadus morhua). PCR primers were designed based on the sequences of conserved motifs in available fish desaturases and used to isolate a cDNA fragment from cod li...

journal_title：Lipids

authors： Tocher DR,Zheng X,Schlechtriem C,Hastings N,Dick JR,Teale AJ

更新日期：2006-11-01 00:00:00

abstract：:FA ethyl esters (FAEE) are nonoxidative metabolites of ethanol produced by the esterification of FA and ethanol. FAEE have been implicated as mediators of ethanol-induced organ damage in vivo and in vitro, and are markers of ethanol intake. Upon ethanol intake, FAEE are synthesized in the liver and pancreas in signifi...

journal_title：Lipids

authors： Hasaba A,Cluette-Brown JE,Laposata M

更新日期：2003-10-01 00:00:00

abstract：:The distribution of dolichol in rat liver was studied. Upon high-speed centrifugation, 9% of the total tissue dolichol was recovered in the supernatant. Dolichol was enclosed in vesicles and in lipidic particles which were isolated by gel filtration and density gradient centrifugation. The particles had a diameter of ...

journal_title：Lipids

authors： Löw P,Peterson E,Edlund C,Brunk U,Appelkvist EL

更新日期：1992-01-01 00:00:00

abstract：:The proximate and fatty acid compositions of the commercially important fish species (Engraulis encrasicolus, Alosa alosa, Belone belone, Scorpaena porcus, Pomatomus saltatrix, Mullus barbatus) from the Sinop region of the Black Sea were examined. The fat contents ranged from 1.26% (for scorpion fish) to 18.12% (for s...

journal_title：Lipids

authors： Kocatepe D,Turan H

更新日期：2012-06-01 00:00:00

abstract：:The mechanism of the self-assembly of the lamellar structure of natural stratum corneum lipids (SCL) has been a subject of considerable interest. We have examined this question by using a synthetic pseudo-ceramide (sphingolipid E, SLE) which was analogous to the naturally occurring ceramide type 2. The thermotropic pr...

journal_title：Lipids

authors： Mizushima H,Fukasawa J,Suzuki T

更新日期：1995-04-01 00:00:00

abstract：:In their diversity, speciation, and sheer numerical superiority, few should question that insects are the dominant life-form on earth. Their utilization of the multifunctional isopentenoids to regulate their life processes is equally diverse. To catalog or even summarize the contribution of isopentenoids in the regula...

journal_title：Lipids

authors： Bowers WS

更新日期：1978-10-01 00:00:00

abstract：:Earlier studies showed that during the first 20 to 25 seconds of aggregation induced by thrombin (0.1 U/mL) or adenosine diphosphate (ADP) (2 microM) of rabbit or human platelets prelabeled with [3H]palmitic acid, labeled lipid became associated with the cytoskeleton (isolated after lysis with 1% Triton X-100, 5 mM EG...

journal_title：Lipids

authors： Packham MA,Guccione MA,Bryant NL,Livne A

更新日期：1991-07-01 00:00:00

abstract：:The presence of leptin receptors in white adipose tissue (WAT) suggests a type of peripheral control during the development of obesity and other metabolic disorders. Both diet composition and exercise influence serum leptin; however, the effect of their combination on long-term WAT leptin metabolism is unknown. In thi...

journal_title：Lipids

authors： de Queiroz KB,Guimarães JB,Coimbra CC,Rodovalho GV,Carneiro CM,Evangelista EA,Guerra-Sá R

更新日期：2014-01-01 00:00:00

abstract：:The effects of droplet size and emulsifiers on oxidative stability of polyunsaturated TAG in oil-in-water (o/w) emulsions with droplet sizes of 0.806 +/- 0.0690, 3.28 +/- 0.0660, or 10.7 +/- 0.106 microm (mean +/- SD) were investigated. Hydroperoxide contents in the emulsion with a mean droplet size of 0.831 microm we...

journal_title：Lipids

authors： Nakaya K,Ushio H,Matsukawa S,Shimizu M,Ohshima T

更新日期：2005-05-01 00:00:00

abstract：:Recent work in our lab has shown that the chemoprotective fatty acid, conjugated linoleic acid (CLA), inhibits phorbol ester skin tumor promotion in mice. Because little is known about the deposition of CLA into tissues as well as its biological activity, this study compared the incorporation and biological activity o...

journal_title：Lipids

authors： Liu KL,Belury MA

更新日期：1997-07-01 00:00:00

abstract：:Apolipoprotein E (apo E) plays an essential role in lipoprotein metabolism, where it is involved in the clearance of chylomicrons and very low density lipoproteins. Apart from some rare variants, apo E exists in three common isoforms (E2, E3, and E4). The different isoforms have not only been associated with different...

journal_title：Lipids

authors： Wiebe C,Holzem G,Wielckens K,Klingler KR

更新日期：2000-01-01 00:00:00

abstract：:The naturally occurring (6Z)-(±)-2-methoxy-6-hexadecenoic acid (1) and (6Z)-(±)-2-methoxy-6-octadecenoic acid (2) were synthesized in 7-8 steps with 38 and 13% overall yields, respectively, by using an acetylide coupling approach, which made it possible to obtain a 100% cis-stereochemistry for the double bonds. In a s...

journal_title：Lipids

authors： Carballeira NM,Montano N,Morales C,Mooney J,Torres X,Díaz D,Sanabria-Rios DJ

更新日期：2017-06-01 00:00:00

abstract：:This study was designed to determine the nutritional lipid requirement of Manchurian trout and to investigate the effects of lipid concentrations on the antioxidant status in larvae with experimental diets with different lipid levels. Oxidative stress differences between different organs and tissues were also assessed...

journal_title：Lipids

authors： Zhang H,Mu Z,Xu L,Xu G,Liu M,Shan A

更新日期：2009-07-01 00:00:00

abstract：:Lipids from bovine optic nerve were analyzed. The total content of 16.5% by weight included 27.2% nonpolar lipids, 26.1% glycolipids, and 46.7% phospholipids by weight. Free cholesterol was the major component of the nonpolar lipid fraction. The cerebrosides, 73.5% of total glycolipids, were separated by thin layer ch...

journal_title：Lipids

authors： Das SK,Steen ME,McCullough MS,Bhattacharyya DK

更新日期：1978-10-01 00:00:00

abstract：:The artificial rearing model was used to investigate the effects of short-term exposure to ethanol on growth and fatty acid composition of forebrain (FB) and cerebellum (CB) during the brain growth spurt in either n-3 fatty acid-adequate (AD) or n-3 deficient (DEF) rat pups. On postnatal day 5, offspring of female rat...

journal_title：Lipids

authors： Ward GR,Xing HC,Wainwright PE

更新日期：1999-11-01 00:00:00

abstract：:Serum opacity factor (SOF) is a streptococcal protein that disrupts the structure of human high density lipoproteins (HDL) releasing lipid-free apo A-I while forming a large cholesteryl ester-rich particle and a small neo HDL. Given its low cholesterol and high phospholipid contents, we tested the hypotheses that neo ...

journal_title：Lipids

authors： Tchoua U,Rosales C,Tang D,Gillard BK,Vaughan A,Lin HY,Courtney HS,Pownall HJ

更新日期：2010-12-01 00:00:00

abstract：:Male and female weanling rats that were born to dams fed a diet low in linolenic acid received diets of 15% lipids by weight containing 45% elaidic acid (as trielaidin) and 8.5% or 0.1% linolenic acid for 10 weeks. Four other groups, in which palmitic or oleic acid replaced elaidic acid in the diet, served as controls...

journal_title：Lipids

authors： Astorg PO,Chevalier J

更新日期：1987-12-01 00:00:00

abstract：:The purpose of the present study was to investigate the effects of gamma linolenic acid (GLA) on cardiovascular responses to psychosocial stress (isolation) and to pressor hormones in the genetically borderline hypertensive rat (SHR X WKY). Adult male SHR X WKY were divided into two groups following five weeks of grou...

journal_title：Lipids

authors： Mills DE,Summers MR,Ward RP

更新日期：1985-09-01 00:00:00

abstract：:If an increased consumption of alpha-linolenic acid (ALA) is to be promoted in parallel with that of n-3 long-chain-rich food, it is necessary to consider to what extent dietary ALA can be absorbed, transported, stored, and converted into long-chain derivatives. We investigated these processes in male hamsters, over a...

journal_title：Lipids

authors： Morise A,Combe N,Boué C,Legrand P,Catheline D,Delplanque B,Fénart E,Weill P,Hermier D

更新日期：2004-04-01 00:00:00

abstract：:Studies are reported on the capacity of isolated rat renal papilla (inner medulla) to synthesize and release prostaglandin (PG) E from endogenous and exogenous precursor(s) during development of an essential fatty acid (EFA) deficiency in the rat. Weanling (21-day-old) male Sprague-Dawley rats were fed a fat-free diet...

journal_title：Lipids

authors： Dunham EW,Balasingam M,Privett OS,Nickell EC

更新日期：1978-12-01 00:00:00