Abstract:
:Lipids from bovine optic nerve were analyzed. The total content of 16.5% by weight included 27.2% nonpolar lipids, 26.1% glycolipids, and 46.7% phospholipids by weight. Free cholesterol was the major component of the nonpolar lipid fraction. The cerebrosides, 73.5% of total glycolipids, were separated by thin layer chromatography (TLC) into two bands (upper and lower) that were present in equal proportion. Cerebroside sulfates comprised about 27.5% of total glycolipids. Gangliosides were also detected in the glycolipid fraction. In order of predominance, choline glycerophospholipids, ethanolamine glycerophospholipids, ethanolamine plasmalogens, serine glycerophospholipids, sphingomyelins, and inositol glycerophospholipids were the major phospholipids. Palmitoyl (16:0), stearoyl (18:0), and oleoyl (18:1) groups were the major acyl groups in all neutral and phospholipid classes. However, ethanolamine glycerophospholipids, serine glycerophospholipids, and inositol glycerophospholipids contained a large percentage of 22:6 (docosahexaenoyl) group. The major alk-1-enyl groups of the plasmalogens were 16:0, 18:0, and 18:1. Steroyl (18:0), lignoceroyl (24:0), and nervonoyl (24:1) were the major acyl groups in all sphingolipids. Lower cerebroside band and cerebroside sulfates contained large amount of hydroxylignoceroyl (cerebronoyl) and hydroxynervonoyl groups.
journal_name
Lipidsjournal_title
Lipidsauthors
Das SK,Steen ME,McCullough MS,Bhattacharyya DKdoi
10.1007/BF02533745subject
Has Abstractpub_date
1978-10-01 00:00:00pages
679-84issue
10eissn
0024-4201issn
1558-9307journal_volume
13pub_type
杂志文章相关文献
LIPIDS文献大全abstract::The reaction products of alpha-tocopherol and its model compound, 2,2,5,7,8-pentamethylchroman-6-ol, during the autoxidation of methyl linoleate at 37 C were investigated. Two isomeric trimers were obtained as the major reaction products of alpha-tocopherol, and a trimer was obtained as that of its model chroman. The ...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/BF02536221
更新日期:1988-08-01 00:00:00
abstract::The objective of the present studies was to examine the effect of dietary fat on the lipid composition of rat colonocytes and their utilization of short-chain fatty acids (SCFA). Rats were fed 14% beef fat, fish oil or safflower oil plus 2% corn oil in a semi-synthetic base diet for 4 wk. Colonocytes were isolated and...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/BF02544340
更新日期:1990-06-01 00:00:00
abstract::In previous studies, zinc-deficient rats force-fed a diet with coconut oil as the major dietary fat developed a fatty liver, whereas zinc-deficient rats force-fed a diet with linseed oil did not. The present study was conducted to elucidate the reason for this phenomenon. In a bifactorial experiment, rats were fed zin...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/BF02537043
更新日期:1995-01-01 00:00:00
abstract::A simple and sensitive method to analyze mixtures of desmosterol, 7-dehydrocholesterol and cholesterol is described. The method involves the oxidative conversion of the sterols with cholesterol oxidase, followed by high performance liquid chromatographic (HPLC) analysis. A C18 reversed phase column (3 microns, 75 X 4....
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/BF02535083
更新日期:1989-07-01 00:00:00
abstract::Treatment of (13S,9Z,11E)-13-hydroperoxy-9,11-octadecadienoic acid (13S-HPODE) with strong alkali resulted in the formation of about 75% of the corresponding hydroxy acid, (13S,9Z,11E)-13-hydroxy-9,11-octadecadienoic acid (13S-HODE), and the remaining 25% of products was a mixture of several oxidized fatty acids, the ...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/BF02522458
更新日期:1996-10-01 00:00:00
abstract::A ubiquitously expressed member of the cytochrome P450 superfamily, CYP51, encodes lanosterol 14alpha-demethylase, the first step in the conversion of lanosterol into cholesterol in mammals. The biosynthetic intermediates of lanosterol 14alpha-demethylation are oxysterols, which inhibit HMG-CoA reductase and sterol sy...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/s11745-002-1016-x
更新日期:2002-12-01 00:00:00
abstract::The degradation of alpha-tocopherol and the formation of alpha-tocopherol and triacylglycerol oxidation products at high temperatures (150-250 degrees C) over a heating period (0-4 h) for a model system ranging between triolein and tripalmitin were modeled by use of an experimental design. The oxidation products of al...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/s11745-001-0777-6
更新日期:2001-07-01 00:00:00
abstract::I-Tiao-Gung, Glycine tomentella, has been used extensively as a traditional herbal medicine to relieve physical pain, but its bioactivity has not been studied systematically. Ninety-five percent ethanol extracts of G. tomentella (GT-E) showed antioxidant activity in human plasma by prolonging the lag phase (+Tlag) of ...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/s11745-005-1482-1
更新日期:2005-11-01 00:00:00
abstract::The evaluation of antioxidant activity in vivo is difficult. In this study, the effects of dietary natural and synthetic antioxidants on the lipid peroxidation in mice were assessed using a biomarker, total hydroxyoctadecadienoic acid (tHODE). Biological samples such as plasma, erythrocytes, and tissues were first red...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/s11745-007-3043-7
更新日期:2007-05-01 00:00:00
abstract::We have examined the possibility that human polymorphonuclear cells exposed to IgA immune complexes can mediate the production of platelet-activating factor (PAF) and oxygen radicals. We found that human IgA and IgG immune aggregates stimulated, to a similar extent, PAF and O2- production by human polymorphonuclear ce...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/BF02536538
更新日期:1991-12-01 00:00:00
abstract::Microtiter plate methods were developed for the enzymatic determination of serum total cholesterol (TC), high density lipoprotein cholesterol (HDL-C) and triglyceride (TG), and for the turbidometric determination of apolipoproteins. The micromethods resulted in accurate, precise values that were in good agreement with...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/BF02535780
更新日期:1993-02-01 00:00:00
abstract::For three weeks, male Sprague-Dawley rats at either four weeks (young) or eight months (adult) of age were pair-fed one of the purified diets free of or containing either 0.2% of oxidized cholesterol mixture (cholesterol oxidation products) or 0.2% of cholesterol. Although the food intake was similar, dietary oxidized...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/BF02536298
更新日期:1995-05-01 00:00:00
abstract::In their diversity, speciation, and sheer numerical superiority, few should question that insects are the dominant life-form on earth. Their utilization of the multifunctional isopentenoids to regulate their life processes is equally diverse. To catalog or even summarize the contribution of isopentenoids in the regula...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/BF02533754
更新日期:1978-10-01 00:00:00
abstract::The importance of n-6 and n-3 polyunsaturated fatty acids (PUFA) in neonatal development, particularly with respect to the developing brain and retina, is well known. This review combines recent information from basic science and clinical studies to highlight recent advances in knowledge on PUFA metabolism and areas w...
journal_title:Lipids
pub_type: 杂志文章,评审
doi:10.1007/s11745-999-0348-x
更新日期:1999-02-01 00:00:00
abstract::Because of the known advantages of coupling high performance liquid chromatography with mass spectrometry (HPLC-MS) in biological fluids, studies on the reversed-phase HPLC-MS system for direct analysis of conjugated bile acids in human bile samples are described. Ten samples of gallbladder bile of apparently healthy ...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/BF02534697
更新日期:1983-01-01 00:00:00
abstract::The artificial rearing model was used to investigate the effects of short-term exposure to ethanol on growth and fatty acid composition of forebrain (FB) and cerebellum (CB) during the brain growth spurt in either n-3 fatty acid-adequate (AD) or n-3 deficient (DEF) rat pups. On postnatal day 5, offspring of female rat...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/s11745-999-0469-2
更新日期:1999-11-01 00:00:00
abstract::Using the spectrofluorimetric method described by Wittenauer et al. [Wittenauer, L.A., Shirai, K., Jackson, R.L., and Johnson, J.D. (1984) Biochem. Biophys. Res. Commun. 118, 894-901] for phospholipase A2 (PLA2) measurement, we have detected a phospholipase activity in Ailsa Craig and in mutant rin tomatoes at their n...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/BF02537801
更新日期:1995-08-01 00:00:00
abstract::Pycnogenol (PYC), an extract of French maritime pine bark (Pinus pinaster), is a potent antioxidant with potential health benefits. Its bioavailabilty has previously been shown by urinary excretion studies of constituents and metabolites of PYC. The aim of this study was to test the effect of PYC supplementation on me...
journal_title:Lipids
pub_type: 临床试验,杂志文章
doi:10.1007/s11745-006-0982-3
更新日期:2002-10-01 00:00:00
abstract::Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disorder. Stress promotes the onset of the NAFLD with a concomitant increment in the activity of the hepatic 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD-1). However, the interaction between the stress and a carbohydrate-enriched diet for t...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/s11745-015-4066-0
更新日期:2015-11-01 00:00:00
abstract::Serum high density lipoprotein is increasingly recognized as a negative risk for cardiovascular disease. The distribution and interrelationship of serum lipids, lipoproteins, anthropometric measurements and blood pressures were determined in some 5,000 children. Children had mean +/- S.D. alpha-lipoprotein cholesterol...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/BF02533576
更新日期:1979-01-01 00:00:00
abstract::Bioassay-guided fractionation of a collection of Moorea bouillonii from Papua New Guinea led to the isolation of a new alkyl amide, mooreamide A (1), along with the cytotoxic apratoxins A-C and E. The planar structure of 1 was elucidated by NMR spectroscopy and mass spectrometry analysis. Structural homology between m...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/s11745-014-3949-9
更新日期:2014-11-01 00:00:00
abstract::Conjugated linoleic acid (CLA) has been shown to cause a reduction in obesity in several species. CLA-induced body fat loss is enhanced when mice are fed coconut oil (CO) and involves increased lipolysis. The objective of this paper was to determine if the CLA-induced lipolysis in mice fed with different oil sources w...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/s11745-013-3835-x
更新日期:2013-11-01 00:00:00
abstract::The effect of hydroperoxy and hydroxy derivatives of various fatty acids on human platelet aggregation was determined to delineate potencies and structure-activity function. In this regard, the 22-carbon n-3 fatty acids are the most potent inhibitors in comparison to the n-6 lipoxygenase derivatives. Submicromolar lev...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/BF02637097
更新日期:1996-03-01 00:00:00
abstract::Using primary rat hepatocyte cultures, the potency of several garlic-derived organosulfur compounds to inhibit cholesterol biosynthesis in toto as well as at early and late steps of this metabolic pathway was compared. Concerning early steps, allicin significantly inhibited incorporation of [14C]acetate into nonsaponi...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/BF02587912
更新日期:1996-12-01 00:00:00
abstract::In vivo intestinal perfusion was used to follow the absorption of three different choline glycerophospholipids (CGP) in guinea pig. These included 1-[3H]palmitoyl-2-acyl-sn-glycero-3-phosphocholine (diacyl-GPC), 1-[3H]-O-hexadecyl-2-acyl-sn-glycero-3-phosphocholine (alkylacyl-GPC) and 1,2-di-O-hexadecyl-sn-glycero-3-p...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/BF02534872
更新日期:1987-01-01 00:00:00
abstract::Both diacyl GPC (glycerylphosphorylcholine) and diacyl GPE (glycerylphosphorylethanolamine) are synthesized in human placental tissue from their respective monoacyl precursors. The origin of the monacyl phosphatides is apparently not the result of placental phosphatide acyl-hydrolase activity. The most likely source i...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/BF02531854
更新日期:1967-09-01 00:00:00
abstract::The effects of hyper- and hypothyroidism on enzyme activities involved in phospholipid metabolism in the rat liver were studied. Hyperthyroidism significantly decreases activities of both microsomal acyl-CoA:glycero-3-phosphate acyltransferase (GPAT) (34%, p less than 0.01) and microsomal acyl-CoA:1-acylglycero-3-phos...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/BF02534774
更新日期:1985-12-01 00:00:00
abstract::Studies are reported on the effects of dietary trans fatty acids on the 6- and 9-acyl desaturase activities in the liver microsomes of rats fed essential fatty acid (EFA)-deficient and non-EFA-deficient diets. In experiment I, weanling male rats were fed a semisynthetic diet with either 10% safflower oil (SAF) or 10% ...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/BF02535118
更新日期:1982-01-01 00:00:00
abstract::The present study was performed to investigate the effect of dietary conjugated linoleic acid (CLA) on the growth performance, immune parameters and disease resistance to Aeromonas hydrophila of juvenile Jian carp. A total of 900 juvenile Jian carp (10.71 +/- 0.02 g) were randomly allocated into six groups of each thr...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/s11745-010-3425-0
更新日期:2010-06-01 00:00:00
abstract::A method was developed to analyze and quantify volatile fatty acids (VFA) such as acetic, propionic, butyric, isobutyric, valeric and isovaleric acids in biological specimens. To obtain good sample transfer into the chromatographic system an organic solvent had to be used together with an aqueous milieu, thus improvin...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/BF02537302
更新日期:1987-03-01 00:00:00