High Sucrose Intake Ameliorates the Accumulation of Hepatic Triacylglycerol Promoted by Restraint Stress in Young Rats.

Abstract:

:Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disorder. Stress promotes the onset of the NAFLD with a concomitant increment in the activity of the hepatic 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD-1). However, the interaction between the stress and a carbohydrate-enriched diet for the development of NAFLD in young animals is unknown. In the present study, we evaluated the impact of chronic stress on the hepatic triacylglycerol level of young rats fed or not with a high sucrose-diet. For doing this, 21-day old male Wistar rats were allocated into 4 groups: control (C), chronic restraint stress (St), high-sucrose diet (S30), and chronic restraint stress plus a 30 % sucrose diet (St + S30). Chronic restraint stress consisted of 1-hour daily session, 5 days per week and for 4 weeks. Rats were fed with a standard chow and tap water (C group) or 30 % sucrose diluted in water (S30 group). The St + S30 groups consumed less solid food but had an elevated visceral fat accumulation in comparison with the St group. The St group showed a high level of serum corticosterone and a high activity of the hepatic 11β-HSD-1 concomitantly to the augmentation of hepatic steatosis signs, a high hepatic triacylglycerol content, and hepatic oxidative stress. Conversely, the high-sucrose intake in stressed rats (St + S30 group) reduced the hepatic 11β-HSD-1 activity, the level of serum corticosterone, and the hepatic triacylglycerol content. Present findings show that a high-sucrose diet ameliorates the triacylglycerol accumulation in liver promoted by the restraint stress in young male rats.

journal_name

Lipids

journal_title

Lipids

authors

Corona-Pérez A,Díaz-Muñoz M,Rodríguez IS,Cuevas E,Martínez-Gómez M,Castelán F,Rodríguez-Antolín J,Nicolás-Toledo L

doi

10.1007/s11745-015-4066-0

subject

Has Abstract

pub_date

2015-11-01 00:00:00

pages

1103-13

issue

11

eissn

0024-4201

issn

1558-9307

pii

10.1007/s11745-015-4066-0

journal_volume

50

pub_type

杂志文章

相关文献

LIPIDS文献大全
  • Rapid and improved method for the determination of bile acids in human feces using MS.

    abstract::A simple method for the determination of bile acids in adult human fecal samples using GC-MS is described. Bile acids are directly extracted from feces by ethanol (95%) containing 0.1 N NaOH. Extracts are purified by passage through a reversed-phase C18 silica cartridge and then analyzed by GC-MS. The present study ha...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/s11745-002-1005-0

    authors: Perwaiz S,Mignault D,Tuchweber B,Yousef IM

    更新日期:2002-11-01 00:00:00

  • Modeling of alpha-tocopherol loss and oxidation products formed during thermoxidation in triolein and tripalmitin mixtures.

    abstract::The degradation of alpha-tocopherol and the formation of alpha-tocopherol and triacylglycerol oxidation products at high temperatures (150-250 degrees C) over a heating period (0-4 h) for a model system ranging between triolein and tripalmitin were modeled by use of an experimental design. The oxidation products of al...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/s11745-001-0777-6

    authors: Verleyen T,Kamal-Eldin A,Dobarganes C,Verhe R,Dewettinck K,Huyghebaert A

    更新日期:2001-07-01 00:00:00

  • The effects of a dietary oxidized oil on lipid metabolism in rats.

    abstract::This study was carried out to investigate the effects of a dietary oxidized oil on lipid metabolism in rats, particularly the desaturation of fatty acids. Two groups of rats were fed initially for a period of 35 d diets containing 10% of either fresh oil or thermally treated oil (150 degrees C, 6 d). The dietary fats ...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/s11745-999-0418-0

    authors: Eder K

    更新日期:1999-07-01 00:00:00

  • Fatty acids of cerebrosides in different regions of the developing foetal brain.

    abstract::The fatty acid composition of cerebrosides of developing foetal human brain and regional variations, if any, during intrauterine life were studied. While palmitic and stearic acids were the predominant normal fatty acids throughout intrauterine life, long chain fatty acids, like lignoceric and nervonic acids, which we...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02533635

    authors: Rao PS

    更新日期:1977-04-01 00:00:00

  • Fish oil fatty acid esters of phytosterols alter plasma lipids but not red blood cell fragility in hamsters.

    abstract::In an attempt to combine the hypocholesterolemic properties of plant sterols with the hypotriglyceridemic action of fish oil FA, plant sterols have recently been esterified to fish oil n-3 PUFA. The objective of this study was to determine the effects of plant sterols esterified to n-3 PUFA on plasma lipid levels and ...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/s11745-005-1432-y

    authors: Demonty I,Ebine N,Jia X,Jones PJ

    更新日期:2005-07-01 00:00:00

  • Initiation of lipid peroxidation by a peroxidase/hydrogen peroxide/halide system.

    abstract::A lactoperoxidase/H2O2/halide system caused the initiation of linoleate peroxidation as indicated by diene conjugation. Coupled lipid peroxidation was accelerated by iodide, chloride and bromide ions at pH 4.0 and 6.2. No peroxidation occurred in the presence of H2O2 or lactoperoxidase alone. The rate of linoleate per...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02534549

    authors: Kanner J,Kinsella JE

    更新日期:1983-03-01 00:00:00

  • Decrease in alkaline triglyceride lipase in primary cultured hepatocytes from mice with sarcoma 180.

    abstract::Primary cultured hepatocytes from normal mice and mice with Sarcoma 180 were characterized. The viability of freshly isolated hepatocytes from both sources was over 90% and the cells had a relatively stable population of DNA for a minimum of three days. After incubation with (3H)leucine, the syntheses and secretions o...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02534229

    authors: Masuno H,Okuda H

    更新日期:1985-07-01 00:00:00

  • Structures of the ceramides from porcine palatal stratum corneum.

    abstract::Ceramides are the major type of lipid found in stratum corneum from the skin, gingiva and hard palate. The present study examined the ceramides of the stratum corneum from the hard palate. Six fractions of ceramides were isolated by preparative thin-layer chromatography. The least polar fraction contained an unusual a...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/s11745-009-3283-9

    authors: Hill JR,Wertz PW

    更新日期:2009-03-01 00:00:00

  • Glyceroglycolipids Affect Uptake of Carotenoids Solubilized in Mixed Micelles by Human Intestinal Caco-2 Cells.

    abstract::We previously reported that phospholipids markedly affected the uptake of carotenoids solubilized in mixed micelles by human intestinal Caco-2 cells. In the present study, we found that two classes of dietary glyceroglycolipids and the corresponding lysoglyceroglycolipids affected uptake of β-carotene and lutein by di...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/s11745-015-4033-9

    authors: Kotake-Nara E,Yonekura L,Nagao A

    更新日期:2015-09-01 00:00:00

  • Measurements of Singlet Oxygen-Quenching Activity of Vitamin E Homologs and Palm Oil and Soybean Extracts in a Micellar Solution.

    abstract::Recently, a new assay method that can quantify the singlet oxygen-absorption capacity (SOAC) of antioxidants (AO) and food extracts in homogeneous organic solvents has been proposed. In the present study, second-order rate constants (kQ ) for the reaction of singlet oxygen (1 O2 ) with vitamin E homologs (α-, β-, γ-, ...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1002/lipd.12053

    authors: Mukai K,Ishikawa E,Ouchi A,Nagaoka SI,Abe K,Suzuki T,Izumisawa K

    更新日期:2018-06-01 00:00:00

  • Conversion of linoleic acid hydroperoxide by soybean lipoxygenase in the presence of guaiacol: identification of the reaction products.

    abstract::Linoleic acid hydroperoxide formed by soybean lipoxygenase was metabolized by the same enzyme in the presence of guaiacol. The products of this reaction included, trihydroxyoctadecenoic acids, hydroperoxydihydroxyoctadecenoic acids, hydroxyepoxyoctadecenoic acids, dihydroxyoctadecenoic acids, hydroxyoctadecadienoic ac...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02532331

    authors: Streckert G,Stan HJ

    更新日期:1975-12-01 00:00:00

  • Preparation of defined molecular species of lactosylceramide by chemical deacylation and reacylation with N-succinimidyl fatty acid esters.

    abstract::A procedure for the preparation of specific molecular species of D-erythro-lactosylceramide involving deacylation and reacylation of lactosylceramide prepared from bovine brain gangliosides is described. Lactosylceramide was N-deacylated by alkaline hydrolysis and the resulting four lysolactosylceramides, which contai...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02538917

    authors: Kadowaki H,Grant MA

    更新日期:1994-10-01 00:00:00

  • A novel spectrophotometric assay for lipase activity utilizing cis-parinaric acid.

    abstract::A new spectrophotometric assay for determining the activity of acylglycerol hydrolases (lipases, E.C. 3.1.1.3) was developed and optimized for yeast lipase (Candida cylindracea). Studies with porcine pancreatic lipase were also conducted and the influence of various detergents and divalent cations on the assay was eva...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02535132

    authors: Rogel AM,Stone WL,Adebonojo FO

    更新日期:1989-06-01 00:00:00

  • Cyclic fatty acids found in frying oils are detoxified via classical drug metabolic pathway but also by β-oxidation and eliminated as conjugates in rats.

    abstract::Cyclic fatty acid monomers (CFAM) are mainly formed during heat treatments, such as frying, of edible oils. These fatty acids are mixtures of disubstituted five- or six-carbon-membered ring structures. Some earlier studies have suggested that some of these molecules could be metabolized and detoxified, but so far, nei...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/s11745-015-3997-9

    authors: Desmarais A,Pujos-Guillot E,Lyan B,Martin JF,Leblanc N,Angers P,Sébédio JL

    更新日期:2015-04-01 00:00:00

  • Analysis of conjugated bile acids by high performance liquid chromatography and mass spectrometry.

    abstract::Because of the known advantages of coupling high performance liquid chromatography with mass spectrometry (HPLC-MS) in biological fluids, studies on the reversed-phase HPLC-MS system for direct analysis of conjugated bile acids in human bile samples are described. Ten samples of gallbladder bile of apparently healthy ...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02534697

    authors: Mingrone G,Greco AV,Boniforti L,Passi S

    更新日期:1983-01-01 00:00:00

  • Diminished macrophage cholesterol removal rate by the altered HDL metabolism in the Nagase analbuminemic rat.

    abstract::Dyslipoproteinemia of the Nagase analbuminemic rat (NAR) is characterized by elevated concentrations of VLDL and LDL attributed to increased rates of liver lipoprotein synthesis. Increased lysophosphatidylcholine (LPC) in NAR HDL has been attributed to high plasma LCAT activity. We show here that, as compared with Spr...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/s11745-006-5017-6

    authors: Catanozi S,Rocha JC,Passarelli M,Mesquita CH,Suguiama VY,Guzzo ML,dos Santos Filho A,Quintão EC,Nakandakare ER

    更新日期:2006-07-01 00:00:00

  • Maternally-supplied fish oil alters piglet immune cell fatty acid profile and eicosanoid production.

    abstract::This study was designed to examine the incorporation of omega-3 (n-3) fatty acids into the immune tissues of pigs nursing fish oil-fed sows and to determine the effect of maternal dietary n-3 consumption on in vitro immune cell eicosanoid production. On day 107 of gestation, 12 sows were randomly allotted to a diet co...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02535986

    authors: Fritsche KL,Alexander DW,Cassity NA,Huang SC

    更新日期:1993-08-01 00:00:00

  • Derivatization of keto fatty acids, X: Synthesis of thiazanones.

    abstract::The synthesis of alkyl chain-substituted thiazanones from oxo fatty esters and a long chain aldehyde is reported. Four oxo compounds-methyl 10-oxoundecanoate, methyl 9-oxooctadecanoate, methyl 9,10-dioxooctadecanoate and octadecanal-were allowed to react with β-mercaptopropionic acid in the presence of ammonium carbon...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02537284

    authors: Khan A,Husain SR,Ahmad F,Siddiqui MS,Pimlott W

    更新日期:1987-08-01 00:00:00

  • Short-term effects of 3-hydroxy-3-methylglutaryl-CoA reductase inhibitor on cholesterol and bile acid synthesis in humans.

    abstract::Competitive inhibitors of 3-hydroxy-3-methylglutaryl-CoA reductase improve hypercholesterolemia. However, reports about the effects of these agents on bile acid synthesis, the metabolic pathway of cholesterol, are conflicting. We studied the short-term effect on one of these agents, pravastatin, on bile acid synthesis...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/s11745-997-0112-2

    authors: Yoshida T,Honda A,Shoda J,Abei M,Matsuzaki Y,Tanaka N,Miyazaki H,Osuga T

    更新日期:1997-08-01 00:00:00

  • Regulatory function of pyruvate dehydrogenase and the mitochondrion in lipogenesis.

    abstract::The activity of pyruvate dehydrogenase from freshly isolated mitochondria was shown to be dependent upon the nutritional and metabolic state of the animal prior to sacrifice, such that mitochondria from the livers of 48 hr starved, diabetic, or high fat fed rats had lower enzyme activity than normal, chow fed rats. Th...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02532317

    authors: Mapes JP,Harris RA

    更新日期:1975-12-01 00:00:00

  • Atherogenesis in swine fed several types of lipid-cholesterol diets.

    abstract::Eighteen-month-old Nebraska strain minipigs were fed diets containing 2% cholesterol and 20% corn oil, lard, or coconut oil for 12 to 18 months. Concentrations of serum total lipid, total cholesterol, and total phospholipid increased 200 to 300% with each diet. Changes in serum concentrations of Sf 20+ and Sf 0-20 lip...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02533395

    authors: Goldsmith DP,Jacob HP

    更新日期:1978-03-01 00:00:00

  • Enteral absorption in man of eicosapentaenoic acid in different chemical forms.

    abstract::After administering the equivalent of 1 g of eicosapentaenoic acid (EPA) in four different chemical forms, the kinetics of EPA incorporation into plasma triglycerides (TG) were compared by gas liquid chromatography on a capillary column following separation of the lipid fraction by thin layer chromatography. EPA incor...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02533970

    authors: el Boustani S,Colette C,Monnier L,Descomps B,Crastes de Paulet A,Mendy F

    更新日期:1987-10-01 00:00:00

  • The effects of phenobarbital on biliary lipid metabolism in cholesterol gallstone subjects.

    abstract::The effect of 1.7-2.2 mg/day oral phenobarbital over short (1 MO) and long term (6-24 MO) treatment on primary bile acid (BA) secretion, composition, synthesis, pool size, and enterohepatic cycling rates as well as phospholipid (PL) and cholesterol (C) secretion rates and biliary composition was determined in 12 asymp...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02533915

    authors: Redinger RN

    更新日期:1979-03-01 00:00:00

  • Tocopherol-phospholipid liposomes: maximum content and stability to serum proteins.

    abstract::This study addresses two questions: 1) what is the maximum amount of tocopherol that can be contained in egg phosphatidylcholine liposomes, and 2) what is the stability of these vesicles in the presence of serum proteins? These liposomes, made with a French pressure cell, can contain no more than 33 mol% of tocopherol...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02534254

    authors: Halks-Miller M,Guo LS,Hamilton RL Jr

    更新日期:1985-03-01 00:00:00

  • Dynamic features of the rumen metabolism of linoleic acid, linolenic acid and linseed oil measured in vitro.

    abstract::The lipid quality of ruminant products is largely determined by the extent of rumen microbial biohydrogenation (BH) of polyunsaturated fatty acids (FAs) and the substances formed thereby. In vitro batch incubations with mixed rumen bacteria were tracked over 24 h to characterize the profiles and kinetics of the BH pro...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/s11745-007-3032-x

    authors: Jouany JP,Lassalas B,Doreau M,Glasser F

    更新日期:2007-04-01 00:00:00

  • Isoprenoid fatty acids from marine sponges. Are sponges selective?

    abstract::The burrowing sponges Anthosigmella varians and Spheciospongia vesparium were found to be rich in the isoprenoid phospholipid fatty acid 4,8,12-trimethyltridecanoic (5.2% and 23%, respectively, of the total fatty acid composition), while the burrowing sponge Chondrilla nucula and the demosponge Agelas dispar contained...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02533980

    authors: Carballeira NM,Maldonado L,Porras B

    更新日期:1987-10-01 00:00:00

  • Conjugated linoleic acids and CLA-containing phospholipids inhibit NO formation in aortic endothelial cells.

    abstract::This study examined the effects of five CLA isomers and the non-conjugated LA on nitric oxide (NO) production, an important modulator of vasodilation, inflammation, and cytotoxicity. Bovine aortic endothelial cells (BAECs) were pretreated with pure CLAs (c9, c11-, c9, t11-, t9, t11-, t10, c12-, c11, c13-CLA) and the n...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/s11745-008-3160-y

    authors: Jenko KJ,Vanderhoek JY

    更新日期:2008-04-01 00:00:00

  • Effect of dietary fats on ovine adipose tissue metabolism.

    abstract::The effects of different dietary fats on ovine adipose tissue metabolism have been investigated. Six-month old sheep were fed for 6 weeks a control diet or diets supplemented with either tallow or a mixture of sunflower seed oil and soybean oil, treated to protect the fats from hydrolysis and hydrogenation in the rume...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02532883

    authors: Vernon RG

    更新日期:1976-09-01 00:00:00

  • Effects of high levels of dietary fats on the growth of azaserine-induced foci in the rat pancreas.

    abstract::Azaserine induced two phenotypically different populations of foci, namely, acidophilic and basophilic foci. The effects of dietary modification during the post-initiation phase of carcinogenesis were examined. A diet of 20% (w/w) unsaturated fat (unsat) compared to a 20% saturated fat (sat) diet or a control diet (5%...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02536413

    authors: Roebuck BD

    更新日期:1986-04-01 00:00:00

  • Inhibition of 12- and 15-lipoxygenase activities and protection of human and tilapia low density lipoprotein oxidation by I-Tiao-Gung (Glycine tomentella).

    abstract::I-Tiao-Gung, Glycine tomentella, has been used extensively as a traditional herbal medicine to relieve physical pain, but its bioactivity has not been studied systematically. Ninety-five percent ethanol extracts of G. tomentella (GT-E) showed antioxidant activity in human plasma by prolonging the lag phase (+Tlag) of ...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/s11745-005-1482-1

    authors: Chen TY,Shiao MS,Pan BS

    更新日期:2005-11-01 00:00:00