Effect of dietary fat on the lipid composition and utilization of short-chain fatty acids by rat colonocytes.

abstract：:cis-5,cis-9-Octadecadienoic acid (2.7%) andcis-5,cis-9,cis-12-octadecatrienoic acid (24.9%) are present in the seed oil ofLarix leptolepis. The double bond positions were identified by ozonolysis and by gas chromatography-mass spectrometry of methoxy derivatives. Small quantities of branched chain acids of various cha...

journal_title：Lipids

authors： Plattner RD,Spencer GF,Kleiman R

更新日期：1975-07-01 00:00:00

abstract：:Recently, lipases have been purified from mammalian, bacterial, fungal and plant sources by different methodologies. Purified lipases subsequently have been characterized for molecular size, metal binding capabilities, glycoside and phosphorus contents, and substrate specificities. Primary structures of several lipase...

journal_title：Lipids

authors： Antonian E

更新日期：1988-12-01 00:00:00

abstract：:Inflammatory disorders are associated with a decrease in iron absorption because of the blockade of iron in storage organs. Fish oils, rich in n-3 PUFA, are used to prevent and treat inflammatory disorders and increase iron absorption in noninflamed rats. Here we examine whether n-3 PUFA prevent inflammation-related h...

journal_title：Lipids

authors： Rodríguez MC,Sáiz MP,Mitjavila MT

更新日期：2003-08-01 00:00:00

abstract：:During our ongoing project on the biosynthesis of R-(+)-octane-1,3-diol the metabolism of linoleic acid was investigated in stored apples after injection of [1-14C]-, [9,10,12,13-3H]-,13C18- and unlabeled substrates. After different incubation periods the products were analyzed by gas chromatography-mass spectroscopy ...

journal_title：Lipids

authors： Beuerle T,Schwab W

更新日期：1999-04-01 00:00:00

abstract：:The lipid quality of ruminant products is largely determined by the extent of rumen microbial biohydrogenation (BH) of polyunsaturated fatty acids (FAs) and the substances formed thereby. In vitro batch incubations with mixed rumen bacteria were tracked over 24 h to characterize the profiles and kinetics of the BH pro...

journal_title：Lipids

authors： Jouany JP,Lassalas B,Doreau M,Glasser F

更新日期：2007-04-01 00:00:00

abstract：:The effects of 2-hexadecynoic acid on the growth and lipid metabolism of cultured 7288 (HTC) cells have been evaluated. Growth was inhibited by the acetylenic acid: the LD50 was 35-85 microM as determined by two methods at low and high cell densities. Reduced growth did not result from damaged plasma membranes as dete...

journal_title：Lipids

authors： Upreti GC,Matocha M,Wood R

更新日期：1981-05-01 00:00:00

abstract：:In an attempt to clarify the mechanism of lipid accumulation inMortierella ramanniana var.angulispora, diacylglycerol acyltransferase (DGAT) in the membrane fraction from this fungus was characterized. The enzyme had an optimum pH of 7.0-7.5, and enzyme activity was blocked by SH-reagents. Metal ions were not essentia...

journal_title：Lipids

authors： Kamisaka Y,Yokochi T,Nakahara T,Suzuki O

更新日期：1993-07-01 00:00:00

abstract：:Lifibrol, a new hypocholesterolemic agent with activity in humans, was examined in normal rats for its short-term and long-term effects on lipid homeostasis. Cholesterol (Chol) synthesis inhibition by lifibrol was demonstrated in vitro in liver minces from normal rats by following [1-14C]acetate ([14C]Ac) and DL-[2-14...

journal_title：Lipids

authors： Bell FP,St John LC

更新日期：1993-12-01 00:00:00

abstract：:Trans FA (TFA) have at least one trans double bond and comprise several isomers and types, including many of the CLA (e.g., c9,t11-18:2 CLA). Some TFA may have adverse effects (e.g., cardiovascular disease), whereas some are thought to have beneficial effects (e.g., anticarcinogenicity). The presence of TFA in human t...

journal_title：Lipids

authors： Shahin AM,McGuire MK,Anderson N,Williams J,McGuire MA

更新日期：2006-02-01 00:00:00

abstract：:For four weeks, groups of eight male and eight female F344/N rats were fed diets containing 15.5, 20, 30 or 40% of energy (en%) as fat. The fat was composed of corn oil and beef tallow with 9 en% from linoleate in all diets. Females had greater mean hepatic alpha-tocopherol levels, whereas males had greater plasma alp...

journal_title：Lipids

authors： Chen HW,Cook LR,Hendrich S

更新日期：1992-11-01 00:00:00

abstract：:With the passage of the U.S. Dietary Supplement Health and Education Act of 1994, dehydroepiandrosterone (DHEA, 5-androsten-3beta-ol-17-one) has become widely available, and a large and growing market has developed for this "fountain of youth." DHEA has been shown to have significant beneficial effects in animals, whi...

journal_title：Lipids

authors： Williams JR

更新日期：2000-03-01 00:00:00

abstract：:The levels of long-chain acyl-CoA in the livers of rats given diets containing various amounts of dietary oils were investigated. Increasing the amount of soybean oil in the diet from 5% to 25% (w/w) led to a 40% increase in long-chain acyl-CoA. With partially hydrogenated marine oil, a sigmoidal dose-response curve w...

journal_title：Lipids

authors： Nilsson A,Thomassen MS,Christiansen E

更新日期：1984-03-01 00:00:00

abstract：:Decreased triacylglycerol synthesis within hepatocytes due to decreased diacylglycerol acyltransferase (DGAT) activity has been suggested to be an important mechanism by which diets rich in fish oil lower plasma triacylglycerol levels. New findings suggest that eicosapentaenoic acid (EPA), and not docosahexaenoic acid...

journal_title：Lipids

authors： Madsen L,Rustan AC,Vaagenes H,Berge K,Dyrøy E,Berge RK

更新日期：1999-09-01 00:00:00

abstract：:Triacylglycerols containing linoleate and linolenate found in vegetable oils were synthesized in gram quantities for oxidation studies. Two acylation methods were examined to convert diacylglycerols or monoacylglycerols to the desired triacylglycerols. Acylations with fatty acid and 1,1'-dicyclohexylcarbodiimide in th...

journal_title：Lipids

authors： Awl RA,Frankel EN,Weisleder D

更新日期：1989-10-01 00:00:00

abstract：:Cnidaria (Calycopsis borchgrevinki, Diphyes antarctica, Stygiomedusa gigantea, Atolla wyvillei, Dimophyes arctica) and Ctenophora (Beroe cucumis, B. forskalii, Pleurobrachia pileus, Bolinopsis infundibulum) were collected near Elephant Island, South Shetland Islands, during January and February 1997 and 1998. Total li...

journal_title：Lipids

authors： Nelson MM,Phleger CF,Mooney BD,Nichols PD

更新日期：2000-05-01 00:00:00

abstract：:Fatty acid compositions of polar lipids and triacylglycerols isolated from eggs of the sea urchin, Arbacia punctulata, were examined before and 15 min after insemination. The main fatty acids present in polar lipids and triacylglycerols were palmitate, palmitoleate, eicosaenoate, arachidonate and eicosapentaenoate, wh...

journal_title：Lipids

authors： Metzman MS,Mastroianni A,Strauss JF

更新日期：1978-11-01 00:00:00

abstract：:A protocol, based on the use of Pseudomonas lipase, is presented to measure quantitatively the amount of triacylglycerols in extracts from cultured cells of tissues. Since the lipase also acts on di- and monoacylglycerols, separation of the extracts by thin-layer chromatography is recommended. In order to allow the li...

journal_title：Lipids

authors： Van Veldhoven PP,Swinnen JV,Esquenet M,Verhoeven G

更新日期：1997-12-01 00:00:00

abstract：:Subjects with echolucent carotid plaques have an increased risk of ischemic cerebrovascular events independent of degree of stenosis. Low plasma lipoprotein lipase (LPL) activity promotes a proatherogenic lipid profile, and delayed chylomicron clearance is a risk factor for atherosclerosis. This study was conducted to...

journal_title：Lipids

authors： Notø AT,Mathiesen EB,Brox J,Björkegren J,Hansen JB

更新日期：2008-04-01 00:00:00

abstract：:This work reports the effect of the apolipoproteins A-I and A-II (apoA-I and apoA-II) on the release of tumor necrosis factor (TNF)-alpha, interleukin (IL)-1beta, IL-8, and IL-1 receptor antagonist (IL-1Ra) and on the oxidative burst of human neutrophils. By themselves, apoA-I and apoA-II do not affect the basal liber...

journal_title：Lipids

authors： Furlaneto CJ,Ribeiro FP,Hatanaka E,Souza GM,Cassatella MA,Campa A

更新日期：2002-09-01 00:00:00

abstract：:Oxidized LDL (oxLDL) may contribute to the accumulation of apoptotic cells in atherosclerotic plaques. Although it is well established in monophasic chemical systems that the highly unsaturated EPA and DHA will oxidize more readily than FA that contain fewer double bonds, our previous studies showed that enrichment of...

journal_title：Lipids

authors： Wu T,Geigerman C,Lee YS,Wander RC

更新日期：2002-08-01 00:00:00

abstract：:The effects of different dietary fats on ovine adipose tissue metabolism have been investigated. Six-month old sheep were fed for 6 weeks a control diet or diets supplemented with either tallow or a mixture of sunflower seed oil and soybean oil, treated to protect the fats from hydrolysis and hydrogenation in the rume...

journal_title：Lipids

authors： Vernon RG

更新日期：1976-09-01 00:00:00

abstract：:A group of homologous, nonmethylene-interrupted dienoic fatty acids (NMID) recently reported in oysters has been found in several other shellfish species and also in other marine phyla. The distribution of most other "normal" fatty acids among several species of shellfish is basically similar but mantle lipids from tw...

journal_title：Lipids

authors： Paradis M,Ackman RG

更新日期：1977-02-01 00:00:00

abstract：:Excessive or inappropriate inflammation and immunosuppression are components of the response to surgery, trauma, injury, and infection in some individuals and these can lead, progressively, to sepsis and septic shock. The hyperinflammation is characterized by the production of inflammatory cytokines, arachidonic acid-...

journal_title：Lipids

authors： Calder PC

更新日期：2004-12-01 00:00:00

abstract：:Policosanol is a poorly absorbed nutritional supplement used primarily for cholesterol management. Findings from previous trials evaluating the effects of policosanol are mixed with early data reporting positive lipid effects while more recent studies indicate negligible efficacy. We hypothesized that re-formulating p...

journal_title：Lipids

authors： Backes JM,Gibson CA,Ruisinger JF,Moriarty PM

更新日期：2011-10-01 00:00:00

abstract：:A recent study on the metabolism of 1-14C-alpha-linolenic acid in the guinea pig revealed that the fur had the highest specific activity of all tissues examined, 48 h after dosing. The present study investigated the pattern of tissue lipid labeling following an oral dose of 1-14C-linoleic acid after the animals had be...

journal_title：Lipids

authors： Fu Z,Attar-Bashi NM,Sinclair AJ

更新日期：2001-03-01 00:00:00

abstract：:In the present study, changes in phospholipid compositions of liver microsomes, erythrocyte membranes, platelets, aorta, cardiac muscle and brain of rats fed olive oil were compared with those of rats fed sunflower oil. Four groups of rats starting at weaning were fed for four weeks a basal diet containing 5 or 25% ol...

journal_title：Lipids

authors： Navarro MD,Periago JL,Pita ML,Hortelano P

更新日期：1994-12-01 00:00:00

abstract：:The aim of this study was to develop a simple method for simultaneous determination of selected cis/cis PUFA-LNA (18:2), ALA (18:3), GLA (18:3), EPA (20:5), and DHA (22:6) by silver ion high-performance liquid chromatography coupled to a diode array detector (Ag-HPLC-DAD). The separation was performed on three Luna SC...

journal_title：Lipids

authors： Czajkowska-Mysłek A,Siekierko U,Gajewska M

更新日期：2016-04-01 00:00:00

abstract：:The amount and composition of lysophosphatidate present in different rat tissues have been estimated by an internal standard method in which a synthetic unnatural isomer (1-heptadecanoyl-rac-glycerol-3-phosphate) was added to the total lipid extracts, and the fatty acid composition of purified lysophosphatidate was de...

journal_title：Lipids

authors： Das AK,Hajra AK

更新日期：1989-04-01 00:00:00

abstract：:In an attempt to combine the hypocholesterolemic properties of plant sterols with the hypotriglyceridemic action of fish oil FA, plant sterols have recently been esterified to fish oil n-3 PUFA. The objective of this study was to determine the effects of plant sterols esterified to n-3 PUFA on plasma lipid levels and ...

journal_title：Lipids

authors： Demonty I,Ebine N,Jia X,Jones PJ

更新日期：2005-07-01 00:00:00

abstract：:A new spectrophotometric assay for determining the activity of acylglycerol hydrolases (lipases, E.C. 3.1.1.3) was developed and optimized for yeast lipase (Candida cylindracea). Studies with porcine pancreatic lipase were also conducted and the influence of various detergents and divalent cations on the assay was eva...

journal_title：Lipids

authors： Rogel AM,Stone WL,Adebonojo FO

更新日期：1989-06-01 00:00:00