Long-chain Acyl-CoA levels in liver from rats fed high-fat diets: is it of significance for an increased peroxisomal beta-oxidation?

abstract：:Primary amines (ammonia, methyl, propyl, octyl, octadecyl, phenyl, benzyl, phenethyl) including methyl esters of amino acids (glycine, DL-alanine, L-valine, L-leucine, L-tyrosine, and L-methionine), and secondary amines (dimethyl, diethyl, dipropyl, diisopropyl, dioctyl, and diphenyl) attack regiospecifically the cent...

journal_title：Lipids

authors： Jie MS,Lau MM

更新日期：2000-10-01 00:00:00

abstract：:Human chylomicron triglyceride (TG) kinetics has been difficult to determine directly owing to technical limitations. This report describes a new method for studying chylomicron metabolism. Healthy volunteers (n = 10) sipped a drink providing 175 mg fat x kg(-1) h(-1) for 7.5 h to produce a steady-state chylomicronemi...

journal_title：Lipids

authors： Park Y,Damron BD,Miles JM,Harris WS

更新日期：2001-02-01 00:00:00

abstract：:The pulp from unerupted calves' teeth was found to contain low levels of glycerol ester hydrolase activity. Solutions in Tris buffer cleared tributyrylglycerol agar and hydrolyzed emulsified olive oil. The average quantity of free fatty acids released in five assays with olive oil was: 2.8, S.D.+/-1.4. Specific activi...

journal_title：Lipids

authors： McMahon KE,Pitas RE,Jensen RG

更新日期：1977-02-01 00:00:00

abstract：:Taurolithocholic acid and deoxycholic acid were perfused into isolated prairie dog livers. Taurolithocholic acid was 7 alpha-hydroxylated to form taurochenodeoxycholic acid, whereas deoxycholic acid was conjugated and 7 alpha-hydroxylated to form taurocholic acid. The low concentrations of secondary bile acids observe...

journal_title：Lipids

authors： Cohen BI,Singhal AK,Mongelli J,Rothschild MA,McSherry CK,Mosbach EH

更新日期：1983-12-01 00:00:00

abstract：:Usually, the chemical structures of cerebrosides in sea creatures are more complicated than those from terrestrial plants and animals. Very little is known about the method for high-throughput molecular profiling of cerebrosides in sea cucumbers. In this study, cerebrosides from four species of edible sea cucumbers, s...

journal_title：Lipids

authors： Jia Z,Cong P,Zhang H,Song Y,Li Z,Xu J,Xue C

更新日期：2015-07-01 00:00:00

abstract：:During our ongoing project on the biosynthesis of R-(+)-octane-1,3-diol the metabolism of linoleic acid was investigated in stored apples after injection of [1-14C]-, [9,10,12,13-3H]-,13C18- and unlabeled substrates. After different incubation periods the products were analyzed by gas chromatography-mass spectroscopy ...

journal_title：Lipids

authors： Beuerle T,Schwab W

更新日期：1999-04-01 00:00:00

abstract：:Subcellular membranes were analyzed for their lipid composition and protein content at two developmental points representing the third instar wandering larvae and prepupal stages of Drosophila. At both stages, phosphatidylethanolamine (PE) and phosphatidylcholine (PC) were the major constituents with phosphatidylinosi...

journal_title：Lipids

authors： Jones HE,Harwood JL,Bowen ID,Griffiths G

更新日期：1992-12-01 00:00:00

abstract：:Hydrolysis of symmetrical acetylenic TG of type AAA [viz., glycerol tri-(4-decynoate), glycerol tri-(6-octadecynoate), glycerol tri-(9-octadecynoate), glycerol tri-(10-undecynoate), and glycerol tri-(13-docosynoate)] in the presence of eight microbial lipases was studied. Novozyme 435 (Candida antarctica), an efficien...

journal_title：Lipids

authors： Jie MS,Fua X,Lau MM,Chye ML

更新日期：2002-10-01 00:00:00

abstract：:Paraoxonase 1 (PON 1) has antioxidant and cardioprotective properties and is abnormally low in type 2 diabetic serum. This study aimed to determine the effect of type 2 diabetes and meals rich in saturated fat and oleic acid on PON1 activity in chylomicrons and very low density lipoproteins (VLDL). PON1 arylesterase a...

journal_title：Lipids

authors： Manning PJ,Jong SA,Ryalls AR,Sutherland WH

更新日期：2012-03-01 00:00:00

abstract：:Using the spectrofluorimetric method described by Wittenauer et al. [Wittenauer, L.A., Shirai, K., Jackson, R.L., and Johnson, J.D. (1984) Biochem. Biophys. Res. Commun. 118, 894-901] for phospholipase A2 (PLA2) measurement, we have detected a phospholipase activity in Ailsa Craig and in mutant rin tomatoes at their n...

journal_title：Lipids

authors： Rouet-Mayer MA,Valentova O,Simond-Côte E,Daussant J,Thévenot C

更新日期：1995-08-01 00:00:00

abstract：:Membrane lipids of photosynthetic organisms consist of glycerophospholipids and glyceroglycolipids. We investigated a method for the simultaneous quantitative analysis of neutral and acidic lipids using HPLC-ELSD, and quantified monogalactosyldiacylglycerol (MGDG), digalactosyldiacylglycerol (DGDG) and sulfoquinovosyl...

journal_title：Lipids

authors： Yunoki K,Sato M,Seki K,Ohkubo T,Tanaka Y,Ohnishi M

更新日期：2009-01-01 00:00:00

abstract：:Pulmonary surfactant, the major surface-active component of which in the adult is dipalmitoylglycerophosphocholine, can be obtained by lavaging lungs with physiological saline. We have previously shown that there is an increase in the amount of phosphatidylcholine in fetal rabbit lung lavage during the latter part of ...

journal_title：Lipids

authors： Rooney SA,Gobran LI

更新日期：1977-12-01 00:00:00

abstract：:Geometric and positional isomers of [1-14C] octadecenoic acids have been synthesized by modifications of published procedures. Positional isomers of octadecynoic acids also have been synthesized to obtain the geometric and positional isomers of the unlabeled octadecenoic acid analogs. The syntheses were accomplished b...

journal_title：Lipids

authors： Valicenti AJ,Pusch FJ,Holman RT

更新日期：1985-04-01 00:00:00

abstract：:The conversion of labeled palmitic, linoleic, arachidonic and docosahexaenoic acids to their respective acyl CoA's was studied in homogenates and microsomes of rat tissues. The highest activity, both in homogenates and microsomes, was seen in liver and heart. There was moderate activity in retina, brain, lung, kidney ...

journal_title：Lipids

authors： Reddy TS,Bazan NG

更新日期：1984-12-01 00:00:00

abstract：:The hypolipidemic drug clofibrate is known to affect the hepatic transport of various organic anions including bilirubin, fatty acids and sulfobromophthalein. Changes in the rate of metabolism and/or intracellular transport have been claimed responsible for the effect. To evaluate these possibilities, the transport of...

journal_title：Lipids

authors： Sorrentino D,Weisiger RA,Bass NM,Licko V

更新日期：1989-05-01 00:00:00

abstract：:The activity of lysosomal acid cholesteryl ester hydrolase (acid CEH, EC 3.1.1.13) in rat liver was determined at 3, 5, 7, 10 and 20 wk following birth. The levels of acid CEH activity showed a marked decrease as rats grew older, whereas those of other lysosomal marker enzymes, such as acid phosphatase, beta-glucuroni...

journal_title：Lipids

authors： Tanaka M,Iio T,Tabata T

更新日期：1987-09-01 00:00:00

abstract：:Multifactorial etiology is involved in premature atherosclerosis related to diabetes. Most of the mechanisms that are responsible for the etiology in diabetes have remained unsolved so far. Type 1 diabetes is associated with a favorable lipid pattern and with microangiopathy, which is not true for type 2 diabetes, whi...

journal_title：Lipids

authors： Gambino R,Pisu E,Pagano G,Cassader M

更新日期：2006-06-01 00:00:00

abstract：:Intact washed human platelets aggregated in response to paf-acether (paf) and did not metabolize [3H]paf at concentrations up to 10 nM. However, when platelets were lysed by exposure to pH 9.5, resulting in 37.5 +/- 2.5% (mean +/- SD, n = 3) lactic dehydrogenase (LDH) release, 20.5 +/- 5.7% of the radioactivity was de...

journal_title：Lipids

authors： Korth R,Bidault J,Palmantier R,Benveniste J,Ninio E

更新日期：1993-03-01 00:00:00

abstract：:This study investigated the influence of PUFA on the properties of mouse skin. Mice (3 wk old) were given free access to oils high in linoleic acid, CLA, or DHA for 4 wk. At the end of the experiment, their skins were compared by both biochemical and histological methods. No significant differences in lipid and collag...

journal_title：Lipids

authors： Oikawa D,Nakanishi T,Nakamura Y,Takahashi Y,Yamamoto T,Shiba N,Tobisa M,Takagi T,Iwamoto H,Tachibana T,Furuse M

更新日期：2003-06-01 00:00:00

abstract：:The purpose of this study was to examine the influence of long-term feeding of dietary fat rich in either n-3 or n-6 fatty acids on the availability of arachidonic acid (20:4n-6) in major phospholipids of gastric mucosa in rats. Three groups of male Wistar rats were fed either a standard diet, a cod liver oil-enriched...

journal_title：Lipids

authors： Olafsson SO,Hallgrimsson J,Gudbjarnason S

更新日期：2000-06-01 00:00:00

abstract：:The effects of 11-deoxycorticosterone and aldosterone on liver delta 5 desaturase activity were examined. Both steroid hormones significantly depressed the conversion of [1-14C] eicosatrienoic acid to arachidonic acid. However, the mechanism of action of each of these hormones was different. The effect of 11-deoxycort...

journal_title：Lipids

authors： de Alaniz MJ,Marra CA

更新日期：1992-08-01 00:00:00

abstract：:Male and female weanling rats that were born to dams fed a diet low in linolenic acid received diets of 15% lipids by weight containing 45% elaidic acid (as trielaidin) and 8.5% or 0.1% linolenic acid for 10 weeks. Four other groups, in which palmitic or oleic acid replaced elaidic acid in the diet, served as controls...

journal_title：Lipids

authors： Astorg PO,Chevalier J

更新日期：1987-12-01 00:00:00

abstract：:We describe a method for the quantitative analysis of molecular species of diacylglycerol and alkylacylglycerol as their diradylglycerobenzoate derivatives. Synthetic internal standards were used to provide quantitative determinations of the low levels of diacylglycerol and alkylacylglycerol and their individual molec...

journal_title：Lipids

authors： Warne TR,Robinson M

更新日期：1990-11-01 00:00:00

abstract：:The present study enumerates the synthesis, spectroscopic characterization, and evaluation of anticancer potential of esters of two n-9 fatty acids viz., oleic acid (OLA) and ricinoleic acid (RCA) with 2,4- or 2,6-diisopropylphenol. The synthesis strategy involved esterification of the hydroxyl group of diisopropylphe...

journal_title：Lipids

authors： Khan AA,Husain A,Jabeen M,Mustafa J,Owais M

更新日期：2012-10-01 00:00:00

abstract：:A sucrose-rich diet (SRD) induces insulin resistance and dyslipidemia with impaired hepatic glucose production and gluconeogenesis, accompanied by altered post-receptor insulin signaling steps. The aim of this study was to examine the effectiveness of fish oil (FO) to reverse or improve the impaired hepatic glucose me...

journal_title：Lipids

authors： Hein GJ,Chicco A,Lombardo YB

更新日期：2012-02-01 00:00:00

abstract：:trans-10,cis-12-CLA (t10,c12-CLA) inhibits lipid deposition in adipose tissue of many species, but it also enhances lipid deposition in liver. We evaluated effects of dietary t10,c12-CLA content and gender on carcass composition, FA profile of selected tissues, and expression of FA synthase (FAS) and stearoyl-CoA desa...

journal_title：Lipids

authors： Viswanadha S,McGilliard ML,Herbein JH

更新日期：2006-08-01 00:00:00

abstract：:SRI 62-834, an analog of the antitumor agent ET-18-OCH3 in which the oxygen atom at carbon atom 2 has been incorporated into a five-membered heterocycle, has been prepared and evaluated as an antitumor agent. The compound exhibited good cytotoxicity in vitro against a variety of tumor cell lines and was as effective a...

journal_title：Lipids

authors： Houlihan WJ,Lee ML,Munder PG,Nemecek GM,Handley DA,Winslow CM,Happy J,Jaeggi C

更新日期：1987-11-01 00:00:00

abstract：:Fatty acid synthetase purified (20 times) from lactating bovine mammary tissue had an approximate mot wt of 485,000. The enzyme had a high content of acidic and hydrophobic amino acid residues; 62±4 sulhydryl groups and one 4' phosphopantetheine residue/mole of enzyme. The enzyme was relatively stable when stored (3 m...

journal_title：Lipids

authors： Kinsella JE,Bruns D,Infante JP

更新日期：1975-04-01 00:00:00

abstract：:Three series of experiments demonstrated that sesame seed and its lignans cause significant elevation of alpha-tocopherol content in rats. In Experiment 1, 20% sesame seed (with a negligible amount of alpha-tocopherol) supplementing 10 (low), 50 (normal), or 250 (high) mg/kg alpha-tocopherol diets (protein and fat con...

journal_title：Lipids

authors： Yamashita K,Iizuka Y,Imai T,Namiki M

更新日期：1995-11-01 00:00:00

abstract：:This study was undertaken to investigate the total plasma fatty acid composition and the relationship between plasma triacylglycerol (TG) levels and liver delta 9 desaturase activity in mice fed n-3 and/or n-6 fatty acid or hydrogenated coconut oil (HCO) (maximum 25 mg/g) supplemented diets. Generally, plasma TG level...

journal_title：Lipids

authors： de Antueno RJ,Cantrill RC,Huang YS,Elliot M,Horrobin DF

更新日期：1993-04-01 00:00:00