Relationship between mouse liver delta 9 desaturase activity and plasma lipids.

abstract：:Seventy-two surgically obtained Dupuytren's disease palmar-fat (DDPF) specimens and 18 location-matched specimens from patients not suffering from this disease (controls) were studied for their total lipid composition and de novo lipogenic activity. Incubation of "DDPF" with 1-[14C]acetate in oxygen produced [14C]palm...

journal_title：Lipids

authors： Rabinowitz JL,Ostermann L Jr,Bora FW,Staeffen J

更新日期：1983-05-01 00:00:00

abstract：:In order to determine the minimal amount of dietary 9-trans, 12-trans-linoleate which can decrease endoperoxide metabolites synthesized and their precursor in rat platelets, graded amounts (0, 0.1, 0.5, 1.0, 2.5%) of the trans-linoleate were fed to rats with a constant amount of all-cis-linoleate (2.5%) for 12 weeks. ...

journal_title：Lipids

authors： Hwang DH,Chanmugam P,Anding R

更新日期：1982-04-01 00:00:00

abstract：:Water and lipid contents, fatty acid distribution, and lipoprotein lipase activity were determined in 11 samples taken from the Omentum Majus of five dry Alpine goats. Samples were chosen to standardize sampling sites using geometric guide marks representative of different adipose tissue sites. Sample location explain...

journal_title：Lipids

authors： Bas P,Gallouin F,Morand-Fehr P

更新日期：1992-06-01 00:00:00

abstract：:The objective of this study was to examine whether whole body oxidation rates of dietary linoleic, alpha-linolenic and oleic acids differ when the acids are provided in identical quantities. Male rats were fed for 10 wk a 15% fat (w/w) diet containing equal amounts of linoleic, alpha-linolenic and oleic acids (22.7, 2...

journal_title：Lipids

authors： Jones PJ

更新日期：1994-07-01 00:00:00

abstract：:The cholesterol-suppressive action of the tocotrienol-rich-fraction (TRF) of palm oil may be due to the effect of its constituent tocotrienols on beta-hydroxy-beta-methylglutaryl coenzyme A (HMG-CoA) reductase activity. The tocotrienols, modulate HMG-CoA reductase activity via a post-transcriptional mechanism. As a co...

journal_title：Lipids

authors： Yu SG,Thomas AM,Gapor A,Tan B,Qureshi N,Qureshi AA

更新日期：2006-05-01 00:00:00

abstract：:This experiment was designed to evaluate the effects of dietary red wine phenolic compounds (WP) and cholesterol on lipid oxidation and transport in rats. For 5 wk, weanling rats were fed polyunsaturated fat diets (n-6/n-3 = 6.4) supplemented or not supplemented with either 3 g/kg diet of cholesterol, 5 g/kg diet of W...

journal_title：Lipids

authors： Frémont L,Gozzelino MT,Linard A

更新日期：2000-09-01 00:00:00

abstract：:Antioxidants may have a role in the prevention of atherosclerosis. In the present trial, we investigated the antioxidant properties of Palm Vitee, a gamma-tocotrienol-, and alpha-tocopherol enriched fraction of palm oil, in patients with carotid atherosclerosis. Serum lipids, fatty acid peroxides, platelet aggregation...

journal_title：Lipids

authors： Tomeo AC,Geller M,Watkins TR,Gapor A,Bierenbaum ML

更新日期：1995-12-01 00:00:00

abstract：:A recent study on the metabolism of 1-14C-alpha-linolenic acid in the guinea pig revealed that the fur had the highest specific activity of all tissues examined, 48 h after dosing. The present study investigated the pattern of tissue lipid labeling following an oral dose of 1-14C-linoleic acid after the animals had be...

journal_title：Lipids

authors： Fu Z,Attar-Bashi NM,Sinclair AJ

更新日期：2001-03-01 00:00:00

abstract：:This paper represents the first synthesis, spectroscopic characterization, and antitumor evaluation of F-, N-, and S-containing C4alpha-FA derivatives of podophyllotoxin. In a synthetic strategy, a FA unit of 4-O-podophyllotoxinyl 12-hydroxyoctadec-Z-9-enoate 2, a derivative of podophyllotoxin, was functionalized at t...

journal_title：Lipids

authors： Mustafa J,Khan SI,Ma G,Walker LA,Khan IA

更新日期：2005-04-01 00:00:00

abstract：:A simple and sensitive method to analyze mixtures of desmosterol, 7-dehydrocholesterol and cholesterol is described. The method involves the oxidative conversion of the sterols with cholesterol oxidase, followed by high performance liquid chromatographic (HPLC) analysis. A C18 reversed phase column (3 microns, 75 X 4....

journal_title：Lipids

authors： Goh EH,Colles SM,Otte KD

更新日期：1989-07-01 00:00:00

abstract：:The incorporation of arachidonic acid (AA) as compared to eicosapentaenoic acid (EPA) into human platelet phospholipids was tested by incubating washed platelets with a known mixture of [3H]AA and [14C]EPA. Following incubation, the platelet lipids were extracted, the individual phospholipids--phosphatidylcholine (PC)...

journal_title：Lipids

authors： Weaver BJ,Holub BJ

更新日期：1985-11-01 00:00:00

abstract：:Oxidized LDL (oxLDL) has been shown to activate the sphingomyelinase pathway producing ceramide in vascular smooth muscle cells. Therefore ceramide, which is a biologically active lipid causing apoptosis in a variety of cells, may be involved in the apoptotic action of oxLDL. In this study, we examined whether cholest...

journal_title：Lipids

authors： Ichi I,Takashima Y,Adachi N,Nakahara K,Kamikawa C,Harada-Shiba M,Kojo S

更新日期：2007-10-01 00:00:00

abstract：:31P Nuclear magnetic resonance (NMR) spectra of human erythrocyte lysates dissolved in sodium cholate were acquired. The narrow resonances of phospholipids were mostly well resolved, allowing identification and accurate quantitative analysis of phospholipid classes of the erythrocyte membranes. The ether-linked phosph...

journal_title：Lipids

authors： Nouri-Sorkhabi MH,Wright LC,Sullivan DR,Kuchel PW

更新日期：1996-07-01 00:00:00

abstract：:Apolipoprotein (apoB) plays a fundamental role in the transport and metabolism of plasma triacylglycerols (TAGs) and cholesterol. Several apoB polymorphic sites have been studied for their potential use as markers for coronary heart disease in the population. In view of the importance of apoB in postprandial metabolis...

journal_title：Lipids

authors： Pérez-Martínez P,Pérez-Jiménez F,Ordovás JM,Moreno JA,Marín C,Moreno R,Jiménez-Gómez Y,Paniagua JA,López-Miranda J

更新日期：2007-03-01 00:00:00

abstract：:This study reports the cloning, functional characterization, tissue expression, and nutritional regulation of a delta6 fatty acyl desaturase of Atlantic cod (Gadus morhua). PCR primers were designed based on the sequences of conserved motifs in available fish desaturases and used to isolate a cDNA fragment from cod li...

journal_title：Lipids

authors： Tocher DR,Zheng X,Schlechtriem C,Hastings N,Dick JR,Teale AJ

更新日期：2006-11-01 00:00:00

abstract：:In tests with purified menhaden oil at 37C and with squalene at 37C and 50C, unsubstituted tocol, 7,8-dimethyl tocol (gamma-tocol), and 8-methyl tocol (sigma-tocol) were superior antioxidants to 5,7-dimethyl tocol and 5,7,8-trimethyl tocol (alpha-tocol). In contrast to previous reports, there were no differences in th...

journal_title：Lipids

authors： Olcott HS,Van der Veen J

更新日期：1968-07-01 00:00:00

abstract：:A method was developed to analyze and quantify volatile fatty acids (VFA) such as acetic, propionic, butyric, isobutyric, valeric and isovaleric acids in biological specimens. To obtain good sample transfer into the chromatographic system an organic solvent had to be used together with an aqueous milieu, thus improvin...

journal_title：Lipids

authors： Fleming SE,Traitler H,Koellreuter B

更新日期：1987-03-01 00:00:00

abstract：:De novo synthesis and mitochondrial elongation of fatty acids have been demonstrated in subcellular fractions from hog and human aorta. Microsomal fatty acid elongation has been shown in hog aorta. The activity catalyzing the formation of fatty acids from acetyl and malonyl CoA was associated with a high molecular wei...

journal_title：Lipids

authors： Slakey LL,Ferrick TJ,Ness GC,Porter JW

更新日期：1979-05-01 00:00:00

abstract：:In a detailed sterol analysis of the marine diatom Phaeodactylum tricornutum, free sterols as well as esterified and glycosylated conjugates were found. When the alga was grown under standard conditions (i.e., at 13 degrees C under white light), 64% of total sterols were steryl glycosides. In all sterol classes, excep...

journal_title：Lipids

authors： Véron B,Billard C,Dauguet JC,Hartmann MA

更新日期：1996-09-01 00:00:00

abstract：:Treatment of (13S,9Z,11E)-13-hydroperoxy-9,11-octadecadienoic acid (13S-HPODE) with strong alkali resulted in the formation of about 75% of the corresponding hydroxy acid, (13S,9Z,11E)-13-hydroxy-9,11-octadecadienoic acid (13S-HODE), and the remaining 25% of products was a mixture of several oxidized fatty acids, the ...

journal_title：Lipids

authors： Gardner HW,Simpson TD,Hamberg M

更新日期：1996-10-01 00:00:00

abstract：:Using the spectrofluorimetric method described by Wittenauer et al. [Wittenauer, L.A., Shirai, K., Jackson, R.L., and Johnson, J.D. (1984) Biochem. Biophys. Res. Commun. 118, 894-901] for phospholipase A2 (PLA2) measurement, we have detected a phospholipase activity in Ailsa Craig and in mutant rin tomatoes at their n...

journal_title：Lipids

authors： Rouet-Mayer MA,Valentova O,Simond-Côte E,Daussant J,Thévenot C

更新日期：1995-08-01 00:00:00

abstract：:A protocol using a dry column method was modified for the extraction of total lipids and the simultaneous separation and quantitation of neutral and polar lipids in human milk. The triacylglycerol, cholesterol, phospholipid and vitamin E contents of the lipid extracts were determined and compared with lipids extracted...

journal_title：Lipids

authors： Collins SE,Jackson MB,Lammi-Keefe CJ,Jensen RG

更新日期：1989-08-01 00:00:00

abstract：:Arachidonic acid was reduced by hydrazine to yield isomeric eicosatrienoic acids with other products. Methylcis,cis,cis-5,8,11-eicosatrienoate was isolated from the products by silver ion chromatography and preparative gas liquid chromatography in 8% yield. The structure was confirmed by spectral studies and oxidative...

journal_title：Lipids

authors： Ghosh A,Koley M,Dutta J

更新日期：1982-04-01 00:00:00

abstract：:The metabolic fate of high density lipoprotein (HDL) sphingomyelin in plasma was studied in rats over a 24-hr period after injection of HDL containing sphingomyelin which was 14C-labeled in the stearic (18:0) or lignoceric acid (24:0) moiety and 3H-labeled in the choline methyl groups. Decay of label in plasma followe...

journal_title：Lipids

authors： Bentejac M,Bugaut M,Delachambre MC,Lecerf J

更新日期：1990-10-01 00:00:00

abstract：:The impact of starch sources differing in their velocities of ruminal degradation on the milk fat of dairy cows was studied. The animals received diets containing a slowly degradable (potatoes) or rapidly degradable (wheat) starch concentrate (40% of the dry matter) in a total mixed diet. Milk fat was the only animal ...

journal_title：Lipids

authors： Jurjanz S,Monteils V,Juaneda P,Laurent F

更新日期：2004-01-01 00:00:00

abstract：:In the present paper, problems in connection with assay of the activity of magnesium-dependent rat liver phosphatidate phosphohydrolase (PAP) are discussed. PAP activity is usually measured by following the production of diacylglycerol or inorganic phosphate from the substrate phosphatidate. These two methods may give...

journal_title：Lipids

authors： Stark M,Humble E

更新日期：1996-10-01 00:00:00

abstract：:This study was carried out to investigate the effects of a dietary oxidized oil on lipid metabolism in rats, particularly the desaturation of fatty acids. Two groups of rats were fed initially for a period of 35 d diets containing 10% of either fresh oil or thermally treated oil (150 degrees C, 6 d). The dietary fats ...

journal_title：Lipids

authors： Eder K

更新日期：1999-07-01 00:00:00

abstract：:The effect of lecithin on jejunal absorption of fatty acids and octadecenoylglycerol was studied in healthy volunteers with a jejunal perfusion system which excluded pancreatic and biliary secretions from the test segment. Lecithin significantly reduced the absorption of oleic acid (P less than 0.05) and octadecenoylg...

journal_title：Lipids

authors： Ammon HV,Thomas PJ,Phillipis SF

更新日期：1979-04-01 00:00:00

abstract：:Dyslipoproteinemia of the Nagase analbuminemic rat (NAR) is characterized by elevated concentrations of VLDL and LDL attributed to increased rates of liver lipoprotein synthesis. Increased lysophosphatidylcholine (LPC) in NAR HDL has been attributed to high plasma LCAT activity. We show here that, as compared with Spr...

journal_title：Lipids

authors： Catanozi S,Rocha JC,Passarelli M,Mesquita CH,Suguiama VY,Guzzo ML,dos Santos Filho A,Quintão EC,Nakandakare ER

更新日期：2006-07-01 00:00:00

abstract：:The physiological role of long-chain fatty acyl-CoA is thought to be primarily in intermediary metabolism of fatty acids. However, recent data show that nM to microM levels of these lipophilic molecules are potent regulators of cell functions in vitro. Although long-chain fatty acyl-CoA are present at several hundred ...

journal_title：Lipids

authors： Gossett RE,Frolov AA,Roths JB,Behnke WD,Kier AB,Schroeder F

更新日期：1996-09-01 00:00:00