Synthesis and in vitro cytotoxic activity of N-, F-, and S-ether derivatives of podophyllotoxin fatty acid adducts.

abstract：:Selected aspects of total parenteral nutrition in man are reviewed with emphasis on carbohydrate, lipid, and hormonal interactions. In an experiment to test for the essentiality of a specific amino acid, a normal adult man received all major and minor nutrients, except lipids, by intravenous alimentation for 48 days. ...

journal_title：Lipids

authors： Wixom RL,Sheng YB,Anderson HL,Yamanaka WK,Terry BE

更新日期：1976-04-01 00:00:00

abstract：:The distribution of dolichol in rat liver was studied. Upon high-speed centrifugation, 9% of the total tissue dolichol was recovered in the supernatant. Dolichol was enclosed in vesicles and in lipidic particles which were isolated by gel filtration and density gradient centrifugation. The particles had a diameter of ...

journal_title：Lipids

authors： Löw P,Peterson E,Edlund C,Brunk U,Appelkvist EL

更新日期：1992-01-01 00:00:00

abstract：:Two simple methods for the synthesis of phosphatidylcholine (lecithin) isotopically labeled in the methyl group of the choline moiety are described. Phosphatidylcholine is converted to phosphatidyl-ethanolamine by enzymic transphosphatidylation, and this is methylated using either methyl iodide or diazomethane to give...

journal_title：Lipids

authors： Smith GA,Montecucco C,Bennett JP

更新日期：1978-01-01 00:00:00

abstract：:In tests with purified menhaden oil at 37C and with squalene at 37C and 50C, unsubstituted tocol, 7,8-dimethyl tocol (gamma-tocol), and 8-methyl tocol (sigma-tocol) were superior antioxidants to 5,7-dimethyl tocol and 5,7,8-trimethyl tocol (alpha-tocol). In contrast to previous reports, there were no differences in th...

journal_title：Lipids

authors： Olcott HS,Van der Veen J

更新日期：1968-07-01 00:00:00

abstract：:The contents and compositions of the 1-O-alk-1'-enyl-2-acyl, 1-O-alkyl-2-acyl, and 1,2-diacyl glycerophospholipids in the muscle and viscera of the ascidian Halocynthia roretzi, and of the gonad of the sea urchin Strongylocentrotus intermedius, which are eaten to some extent in Alaska and in Asia, were analyzed by gas...

journal_title：Lipids

authors： Jeong BY,Ohshima T,Koizumi C

更新日期：1996-01-01 00:00:00

abstract：:Although migrating birds use stored triacylglycerol as their primary fuel for flight, they must retain sufficient stores of omega 6 and omega 3 fatty acids to sustain reproduction after the spring migration. Hepatic monoacylglycerol:acyl-coenzyme A acyltransferase (EC 2.3.1.22) (MGAT) activity is associated with physi...

journal_title：Lipids

authors： Mostafa N,Bhat BG,Coleman RA

更新日期：1994-11-01 00:00:00

abstract：:The growth inhibitory effects of 1-O-octadecyl-2-O-methyl-sn-glycero-3-phosphocholine (ET-18-OCH3) and various liposome compositions of ET-18-OCH3 were compared in a standardized growth inhibition assay utilizing a diverse tumor cell line panel including cell lines expressing multidrug resistance. ET-18-OCH3 and ELL-1...

journal_title：Lipids

authors： Peters AC,Ahmad I,Janoff AS,Pushkareva MY,Mayhew E

更新日期：1997-10-01 00:00:00

abstract：:Lifibrol, a new hypocholesterolemic agent with activity in humans, was examined in normal rats for its short-term and long-term effects on lipid homeostasis. Cholesterol (Chol) synthesis inhibition by lifibrol was demonstrated in vitro in liver minces from normal rats by following [1-14C]acetate ([14C]Ac) and DL-[2-14...

journal_title：Lipids

authors： Bell FP,St John LC

更新日期：1993-12-01 00:00:00

abstract：:Iron and ascorbic acid appear to be the normal catalytic components responsible for the lipid peroxidation reaction in aerobically incubated rat tissue homogenates. The amounts of each present in the catalytically-active fractions of rat liver, brain, testis, and kidney are appropriate to explain the lipid peroxidatio...

journal_title：Lipids

authors： Barber AA

更新日期：1966-03-01 00:00:00

abstract：:Commercial preparations of Candida rugosa lipase (CRL) are mixtures of lipase isoforms used for the hydrolysis and synthesis of various esters. The presence of variable isoforms and the amount of lipolytic protein in the crude lipase preparations lead to a lack of reproducibility of biocatalytic reactions. Purificatio...

journal_title：Lipids

authors： Akoh CC,Lee GC,Shaw JF

更新日期：2004-06-01 00:00:00

abstract：:Weanling rats were fed essential fatty acid-deficient diets, either completely fat-free, or with partially hydrogenated fish oil (PHFO, 28 wt %), or with fractions derived from PHFO containing primarily positional isomers of trans-eicosenoate (20:1, 3 wt %) or trans-docosenoate (22:1, 3 wt %). Control animals were fed...

journal_title：Lipids

authors： Jensen B

更新日期：1976-03-01 00:00:00

abstract：:Exercise training not only improves the plasma lipid profile but also reduces risk of developing coronary heart disease. We investigate whether plasma lipids and high density lipoprotein (HDL) metabolism are affected by aerobic training and whether the high-density lipoprotein cholesterol (HDL-C) levels at baseline in...

journal_title：Lipids

authors： da Silva JL,Maranhão RC,Silva MSM,Dias RG,Freitas FR,Bolani W,Lemos Junior JR,Alves CR,Oliveira PA,Alves GB,Oliveira EM,Negrao CE,Krieger JE,Pereira AC,Silva GA,Souza JP,Vinagre CGC

更新日期：2019-06-01 00:00:00

abstract：:Insulin and dietary fructose independently induce stearoyl-CoA desaturase 1 (SCD1) gene expression in diabetic mouse liver. In the present study, we again used diabetic mice and supplemented a high fructose diet with polyunsaturated fatty acids (PUFA) to determine the selective repression of SCD1 gene expression by di...

journal_title：Lipids

authors： Waters KM,Ntambi JM

更新日期：1996-03-01 00:00:00

abstract：:We recently reported the presence of various cyclopropane fatty acids-among them, cyclopropaneoctanoic acid 2-hexyl-in the adipose tissue of obese women. The aim of this study was to verify whether the presence of cyclopropaneoctanoic acid 2-hexyl in human serum was associated with obesity or chronic kidney disease (b...

journal_title：Lipids

authors： Mika A,Stepnowski P,Chmielewski M,Malgorzewicz S,Kaska L,Proczko M,Ratnicki-Sklucki K,Sledzinski M,Sledzinski T

更新日期：2016-07-01 00:00:00

abstract：:Levels of serum lipids and lipoproteins, and the fatty acid composition of plasma phospholipids, were measured in two genetically comparable, but widely separated, populations. The 1975 mortality rates for ischemic heart disease were significantly higher in one of these populations, the Manitoban residents of pure Ice...

journal_title：Lipids

authors： Skúladóttir GV,Gudmundsdóttir S,Olafsson GB,Sigurdsson SB,Sigfússon N,Axelsson J

更新日期：1995-07-01 00:00:00

abstract：:Dietary fat intake influences plasma glucose concentration through modifying glucose uptake and utilization by adipose and skeletal muscle tissues. In this paper, we studied the effects of a low-fat diet on diaphragm GLUT4 expression and fatty acid composition in control and streptozotocin-induced diabetic rats. Contr...

journal_title：Lipids

authors： Girón MD,Salto R,Hortelano P,Periago JL,Vargas AM,Suárez MD

更新日期：1999-08-01 00:00:00

abstract：:Cholesterol biosynthesis from acetate-2-(14)C by the livers of suckling rats, which is known to be relatively slow, was increased 2-3-fold within 24 hours after severing the bile duct. Cholesterol synthesis by sham-operated litter mates showed no change under similar treatment. Mevalonate biosynthesis from acetate-2-(...

journal_title：Lipids

authors： Harris RA,Rivera ER,Villemez CL Jr,Quackenbush FW

更新日期：1967-03-01 00:00:00

abstract：:Conjugated linoleic acid (CLA) is a collective term that describes different isomers of linoleic acid with conjugated double bonds. Although the main dietary isomer is 9cis,11trans-18:2, which is present in dairy products and ruminant fat, the biological effects of CLA generally have been studied using mixtures in whi...

journal_title：Lipids

authors： Sébédio JL,Angioni E,Chardigny JM,Grégoire S,Juanéda P,Berdeaux O

更新日期：2001-06-01 00:00:00

abstract：:This study was undertaken to determine the effect of various lipid emulsions on the hepato-biliary system in rats. Rats were randomly divided into six groups and infused continuously for 48 hr with either long-chain triglycerides (LCT), medium-chain triglycerides (MCT) or a mixture of MCT and LCT. One group infused wi...

journal_title：Lipids

authors： Rubin M,Halpern Z,Livoff A,Wennberg A,Tietz A,Antebi E,Lichtenberg D

更新日期：1992-05-01 00:00:00

abstract：:Five groups of salmon, of initial mean weight 127 +/- 3 g, were fed increasing levels of dietary linseed oil (LO) in a regression design. The control diet contained capelin oil (FO) only, and the same oil was blended with LO to provide the experimental diets. After an initial period of 40 wk, all groups were switched ...

journal_title：Lipids

authors： Bell JG,Henderson RJ,Tocher DR,Sargent JR

更新日期：2004-03-01 00:00:00

abstract：:Antioxidants may have a role in the prevention of atherosclerosis. In the present trial, we investigated the antioxidant properties of Palm Vitee, a gamma-tocotrienol-, and alpha-tocopherol enriched fraction of palm oil, in patients with carotid atherosclerosis. Serum lipids, fatty acid peroxides, platelet aggregation...

journal_title：Lipids

authors： Tomeo AC,Geller M,Watkins TR,Gapor A,Bierenbaum ML

更新日期：1995-12-01 00:00:00

abstract：:Naturally occurring tetraalkylsubstituted furan fatty acids (F-acids) were tested as potential substrates for soybean lipoxygenase-1. For this purpose, F-acid methyl ester and phosphatidylcholines containing F-acids at the sn-2 position of the glycerol residue were incubated with the enzyme. Oxidation of F-acids only ...

journal_title：Lipids

authors： Batna A,Spiteller G

更新日期：1994-06-01 00:00:00

abstract：:Active lipases were isolated from the culture supernatant of the basidiomycetous fungus Pleurotus sapidus by foam fractionation. The pH value, the gas flow, and the foaming period were systematically varied to optimize the transport of the enzymes into the foam phase. On a 70-mL scale, a maximum recovery of hydrolytic...

journal_title：Lipids

authors： Linke D,Zorn H,Gerken B,Parlar H,Berger RG

更新日期：2005-03-01 00:00:00

abstract：:In experiments on dogs, i.v. administration of platelet-activating factor (PAF) (500 ng/kg) was shown to induce hypotension which, apart from decreased myocardial contractility, was characterized by blood pooling in veins (82.6 +/- 6.8 mL/kg). This was accompanied by restriction of venous return to the heart and reduc...

journal_title：Lipids

authors： Sagach VF,Dmitrieva AV,Braquet P

更新日期：1991-12-01 00:00:00

abstract：:Lutein is an oxygenated carotenoid (xanthophyll) found in dark green leafy vegetables. High intakes of lutein may lower the risk of age-related macular degeneration. Current understanding of human lutein metabolism as it might occur in vivo is incomplete. Therefore, we conducted a feasibility study where we dosed a no...

journal_title：Lipids

authors： de Moura FF,Ho CC,Getachew G,Hickenbottom S,Clifford AJ

更新日期：2005-10-01 00:00:00

abstract：:The diglyceride species of phosphatidylcholines from livers of male rats after treatment of the animals with ethionine (1 mg/g divided among 4 doses 2 hr apart), phenobarbital (80 mg/kg each day for 3 days), or a combination of the two drugs were determined using gas chromatography. Ethionine treatment greatly elevate...

journal_title：Lipids

authors： Dyer RA,Klopfenstein WE

更新日期：1977-11-01 00:00:00

abstract：:Fish easily accumulate n-3 PUFA of exogenous origin, but the underlying mechanisms are not well established in the whole animal. This study was undertaken to investigate whether this feature was physiologically associated with mitochondrial and peroxisomal capacities that differentially affect FA oxidation. For this p...

journal_title：Lipids

authors： Du ZY,Demizieux L,Degrace P,Gresti J,Moindrot B,Liu YJ,Tian LX,Cao JM,Clouet P

更新日期：2004-09-01 00:00:00

abstract：:Palm oil is one of the most important edible oils in the world. Its composition (rich in palmitate and oleate) make it suitable for general food uses but its utility could be increased if its fatty acid quality could be varied. In this study, we have modified a palm olein fraction by transesterification with the n-3 p...

journal_title：Lipids

authors： Zainal Z,Longman AJ,Hurst S,Duggan K,Hughes CE,Caterson B,Harwood JL

更新日期：2009-07-01 00:00:00

abstract：:Excessive or inappropriate inflammation and immunosuppression are components of the response to surgery, trauma, injury, and infection in some individuals and these can lead, progressively, to sepsis and septic shock. The hyperinflammation is characterized by the production of inflammatory cytokines, arachidonic acid-...

journal_title：Lipids

authors： Calder PC

更新日期：2004-12-01 00:00:00

abstract：:The activity of lysosomal acid cholesteryl ester hydrolase (acid CEH, EC 3.1.1.13) in rat liver was determined at 3, 5, 7, 10 and 20 wk following birth. The levels of acid CEH activity showed a marked decrease as rats grew older, whereas those of other lysosomal marker enzymes, such as acid phosphatase, beta-glucuroni...

journal_title：Lipids

authors： Tanaka M,Iio T,Tabata T

更新日期：1987-09-01 00:00:00