Effects of ethionine and phenobarbital on the phosphatidylcholines of rat liver.

abstract：:Insulin and dietary fructose independently induce stearoyl-CoA desaturase 1 (SCD1) gene expression in diabetic mouse liver. In the present study, we again used diabetic mice and supplemented a high fructose diet with polyunsaturated fatty acids (PUFA) to determine the selective repression of SCD1 gene expression by di...

journal_title：Lipids

authors： Waters KM,Ntambi JM

更新日期：1996-03-01 00:00:00

abstract：:Hydrolysis of symmetrical acetylenic TG of type AAA [viz., glycerol tri-(4-decynoate), glycerol tri-(6-octadecynoate), glycerol tri-(9-octadecynoate), glycerol tri-(10-undecynoate), and glycerol tri-(13-docosynoate)] in the presence of eight microbial lipases was studied. Novozyme 435 (Candida antarctica), an efficien...

journal_title：Lipids

authors： Jie MS,Fua X,Lau MM,Chye ML

更新日期：2002-10-01 00:00:00

abstract：:Recent work in our lab has shown that the chemoprotective fatty acid, conjugated linoleic acid (CLA), inhibits phorbol ester skin tumor promotion in mice. Because little is known about the deposition of CLA into tissues as well as its biological activity, this study compared the incorporation and biological activity o...

journal_title：Lipids

authors： Liu KL,Belury MA

更新日期：1997-07-01 00:00:00

abstract：:A method has been developed for determination of individual long-chain fatty acyl-CoA esters from heart and skeletal muscle using high performance liquid chromatography (HPLC). The esters were extracted from freeze-clamped tissue of pig and rat hearts and rat skeletal muscle for analysis on a radially compressed C18 5...

journal_title：Lipids

authors： Molaparast-Saless F,Shrago E,Spennetta TL,Donatello S,Kneeland LM,Nellis SH,Liedtke AJ

更新日期：1988-05-01 00:00:00

abstract：:Male weanling rats were fed semi-synthetic diets high in saturated fat (beef tallow) vs high in linoleic acid (safflower oil) with or without high levels of alpha-linolenic acid (linseed oil) for a period of 28 days. The effect of feeding these diets on cholesterol content and fatty acid composition of serum and liver...

journal_title：Lipids

authors： Garg ML,Wierzbicki AA,Thomson AB,Clandinin MT

更新日期：1989-04-01 00:00:00

abstract：:Oxidative stress is thought to play an important role in atherogenesis. The statin group of cholesterol-lowering drugs have been shown to reduce cardiovascular events and possess antioxidant properties. We aimed to assess the effects of simvastatin on a novel measure of prooxidant-antioxidant balance (PAB) in dyslipid...

journal_title：Lipids

authors： Parizadeh SM,Azarpazhooh MR,Moohebati M,Nematy M,Ghayour-Mobarhan M,Tavallaie S,Rahsepar AA,Amini M,Sahebkar A,Mohammadi M,Ferns GA

更新日期：2011-04-01 00:00:00

abstract：:Lecithin-cholesterol acyltransferase (LCAT, EC 2.3.1.43) was assayed in vitro in plasma from normal man, rat, rabbit and dog by following the formation of 14C-cholesteryl esters subsequent to labeling the plasma with 14C-cholesterol in vitro. In all species examined, various local anesthetics were found to inhibit LCA...

journal_title：Lipids

authors： Bell FP,Hubert EV

更新日期：1980-10-01 00:00:00

abstract：:Gallstone formation and dissolution were studied in a prairie dog model of cholesterol (CH) cholelithiasis. Gallstones were induced in 49 prairie dogs by feeding 1.2% CH in a nutritionally adequate semisynthetic diet for 6 wk (period 1). At 6 wk, gallstones had developed in all animals examined. The diets were modifie...

journal_title：Lipids

authors： Cohen BI,Mosbach EH,McSherry CK,Rzigalinski B,Kuroki S

更新日期：1986-09-01 00:00:00

abstract：:Cholesterol itself has very few structural/chemical features suitable for real-time imaging in living cells. Thus, the advent of dehydroergosterol [ergosta-5,7,9(11),22-tetraen-3beta-ol, DHE] the fluorescent sterol most structurally and functionally similar to cholesterol to date, has proven to be a major asset for re...

journal_title：Lipids

authors： McIntosh AL,Atshaves BP,Huang H,Gallegos AM,Kier AB,Schroeder F

更新日期：2008-12-01 00:00:00

abstract：:Peroxisome proliferator-activated receptor alpha (PPARalpha) belongs to the nuclear receptor superfamily that regulates multiple target genes involved in lipid metabolism. Cholesterol ester transfer protein (CETP) is a secreted glycoprotein that modifies high-density lipoprotein (HDL) particles. In humans, plasma CETP...

journal_title：Lipids

authors： Beyer TP,Chen Y,Porter RK,Lu D,Schmidt RJ,Mantlo NB,Konrad RJ,Cao G

更新日期：2008-07-01 00:00:00

abstract：:A group of Angus beef cattle was removed from temperate pastures and fed a very low beta-carotene cereal-based ration in a feedlot for over 300 d. Half the group was supplemented weekly with retinyl palmitate (at the rate of 60,000 IU vitamin A/100 live weight (LW)/day), sufficient to offset clinical vitamin A deficie...

journal_title：Lipids

authors： Siebert BD,Kruk ZA,Davis J,Pitchford WS,Harper GS,Bottema CD

更新日期：2006-04-01 00:00:00

abstract：:We evaluated the effects of dietary lipid class (phospholipid vs. neutral lipid) and level of n-3 long-chain PUFA (LC-PUFA) on the growth, digestive enzymatic activity, and histological organization of the intestine and liver in European sea bass larvae. Fish were fed from the onset of exogenous feeding at 7 to 37 d p...

journal_title：Lipids

authors： Gisbert E,Villeneuve L,Zambonino-Infante JL,Quazuguel P,Cahu CL

更新日期：2005-06-01 00:00:00

abstract：:The permeability of an N-oleoyldihydrosphingomyelin bilayer against glycerol was similar to that of a bilayer of phosphatidylcholine with identical effective hydrophobic chain length. Cholesterol at 1:1 molar ratio reduced the permeability, and also reduced the energy of activation of glycerol penetration, an effect n...

journal_title：Lipids

authors： Tirri LJ,Ayengar NK,Lipton LC,Chatterjie N,Brockerhoff H

更新日期：1978-04-01 00:00:00

abstract：:Groups of C57Bl/6J mice, fed either a cis (C-Diet) or trans diet (T-Diet) were milked without preconditioning at 6, 8, 10 and 12 days postpartum. On day 10, groups of mice were also milked 4, 6 and 18 h after separation of the pups. Except for the 18-h separation, all T-Diet fed animals produced milk of lower fat cont...

journal_title：Lipids

authors： Teter BB,Sampugna J,Keeney M

更新日期：1992-11-01 00:00:00

abstract：:In the present study we evaluated the uptake of ALA and its conversion to EPA + DHA in rats given linseed oil (LSO) in native form or as a microemulsion in whey protein or in lipoid. In a single oral dose study in which rats maintained on rodent pellets deficient in ω-3 fatty acids were intubated with 0.35 g LSO in li...

journal_title：Lipids

authors： Sugasini D,Devaraj VC,Ramesh M,Lokesh BR

更新日期：2014-03-01 00:00:00

abstract：:Linoleic acid was efficiently converted into the two major components of conjugated linoleic acid, 9Z,11E-octadecadienoic (1a) and 10E,12Z-octadecadienoic acid (1b) using either the superbase (n-butyllithium/potassium tert-butoxide) or by simply refluxing with KOH in 1-butanol. In turn, 1a and 1b were separated from e...

journal_title：Lipids

authors： Chen CA,Lu W,Sih CJ

更新日期：1999-08-01 00:00:00

abstract：:Acetate supplementation increases plasma acetate, brain acetyl-CoA, histone acetylation, phosphocreatine levels, and is anti-inflammatory in models of neuroinflammation and neuroborreliosis. Although radiolabeled acetate is incorporated into the cellular lipid pools, the effect that acetate supplementation has on lipi...

journal_title：Lipids

authors： Bhatt DP,Rosenberger TA

更新日期：2014-07-01 00:00:00

abstract：:Type 2 diabetes and dyslipidemia are risk factors for cardiovascular disease. However, mechanisms by which hypertriglyceridemia influences atherogenesis remain unclear. We examined effects of dyslipidemic diabetic serum on macrophage lipid accumulation as a model of foam cell formation. Normal human macrophages were c...

journal_title：Lipids

authors： Wong BX,Kyle RA,Myhill PC,Croft KD,Quinn CM,Jessup W,Yeap BB

更新日期：2011-10-01 00:00:00

abstract：:Administration of 2,2'''-([1-methyl-4, 4-diphenylbutylidene] bis(p-phenyl-eneoxy]) bistriethylamine oxalate (SQ 10,591) at 20 mg/Kg daily for 5 days to cholesterol-fed rabbits resulted in no change in aortic microsomal cholesterol esterification with a palmitoyl coenzyme A substrate or of aortic mitochondrial choleste...

journal_title：Lipids

authors： Morin RJ

更新日期：1975-02-01 00:00:00

abstract：:The effect of 4,4'-diethylamino-ethoxyhexestrol (DH) on acid esterase in rat liver was studied in vivo and in vitro. The acid esterase activity in the livers of rats treated with 0.125% DH for 1 week was found to decrease more than 60% as compared with that in untreated rats. The addition of DH to the incubation mediu...

journal_title：Lipids

authors： Kasama K,Yoshida K,Takeda S,Tsujimura R,Hasegawa S

更新日期：1976-10-01 00:00:00

abstract：:cis-5,cis-9-Octadecadienoic acid (2.7%) andcis-5,cis-9,cis-12-octadecatrienoic acid (24.9%) are present in the seed oil ofLarix leptolepis. The double bond positions were identified by ozonolysis and by gas chromatography-mass spectrometry of methoxy derivatives. Small quantities of branched chain acids of various cha...

journal_title：Lipids

authors： Plattner RD,Spencer GF,Kleiman R

更新日期：1975-07-01 00:00:00

abstract：:The total lipid content, composition of main lipid classes, composition of sterols and composition of fatty acids in the main glycerolipids of Perna viridis were analyzed through four seasons using TLC-FID and GLC. Mussel samples were collected during different seasons between 2003 and 2004 from Shengsi Island, Zhejia...

journal_title：Lipids

authors： Li D,Zhang Y,Sinclair AJ

更新日期：2007-08-01 00:00:00

abstract：:Neutrophils play a major role in inflammation by releasing large amounts of reactive oxygen species (ROS) produced by NADPH oxidase (NOX) and myeloperoxidase (MPO). This ROS overproduction is mediated by phosphorylation of the NOX subunits in an uncontrolled manner. Therefore, targeting neutrophil subunits would repre...

journal_title：Lipids

authors： Liu M,Boussetta T,Makni-Maalej K,Fay M,Driss F,El-Benna J,Lagarde M,Guichardant M

更新日期：2014-01-01 00:00:00

abstract：:A 24-hr pretreatment of cultured human fibroblasts with trifluoperazine induced a marked increase in incorporation of saturated (stearic, palmitic) and unsaturated (oleic, arachidonic) fatty acids into phospholipids (1.5- to 2-fold for 5.10(-5) M trifluoperazine). Concomitantly, incorporation into cholesteryl esters w...

journal_title：Lipids

authors： Mazière C,Mazière JC,Mora L,Auclair M,Polonovski J

更新日期：1988-05-01 00:00:00

abstract：:Mitochondrial cytochrome P450 enzymes (CYP or P450, EC 1.14.13.15) play an important role in metabolism of cholesterol. CYP27A1 hydroxylates cholesterol at position 27 and, thus, initiates cholesterol removal from many extrahepatic tissues. CYP11A1 is a steroidogenic P450 that converts cholesterol to pregnenolone, the...

journal_title：Lipids

authors： Pikuleva IA,Mast N,Liao WL,Turko IV

更新日期：2008-12-01 00:00:00

abstract：:The effects of feeding CLA to hens on newly hatched chick hepatic and carcass lipid content, liver TAG accumulation, and FA incorporation in chick tissues such as liver, heart, brain, and adipose were studied. These tissues were selected owing to their respective roles in lipid assimilation (liver), as a major oxidati...

journal_title：Lipids

authors： Cherian G,Ai W,Goeger MP

更新日期：2005-02-01 00:00:00

abstract：:The purpose of this study was to examine the effect of dietary docosahexaenoic acid (DHA), in the absence of eicosapentaenoic acid, on human immune response (IR). A 120-d study with 11 healthy men was conducted at the Metabolic Research Unit of the Western Human Nutrition Research Center. Four subjects (control group)...

journal_title：Lipids

authors： Kelley DS,Taylor PC,Nelson GJ,Mackey BE

更新日期：1998-06-01 00:00:00

abstract：:The aim of this study was to determine the fatty acid composition and trans fatty acid and fatty acid contents of breast milk in Turkish women and to find the effect of breastfeeding mothers' diet on trans fatty acid and fatty acid composition. Mature milk samples obtained from 50 Turkish nursing women were analyzed. ...

journal_title：Lipids

authors： Samur G,Topcu A,Turan S

更新日期：2009-05-01 00:00:00

abstract：:Potato tuber lipoxygenase (ptLOX) has been shown to catalyze the aerobic formation of at least four major oxygenated derivatives of DHA. Two of the products--7,17(S)- and 10,17(S)-dihydro(pero)xy-DHA [7,17- and 10,17-diH(P)DHA]--were formed from soybean 15-LOX-derived 17(S)-hydro(pero)xy-DHA [17(S)-H(P)DHA], whereas t...

journal_title：Lipids

authors： Butovich IA,Hamberg M,Rådmark O

更新日期：2005-03-01 00:00:00

abstract：:The beta-adrenergic system in cardiac muscle cells is influenced by the n-3 polyunsaturated fatty acid (PUFA) content in cell membranes. This study deals with the specific effect of docosahexaenoic acid (DHA) as compared to other n-3 PUFA, without modification of the arachidonic acid content. Increasing the DHA conten...

journal_title：Lipids

authors： Grynberg A,Fournier A,Sergiel JP,Athias P

更新日期：1996-03-01 00:00:00