Isotopic labeling of phosphatidylcholine in the choline moiety.

abstract：:Dyslipoproteinemia of the Nagase analbuminemic rat (NAR) is characterized by elevated concentrations of VLDL and LDL attributed to increased rates of liver lipoprotein synthesis. Increased lysophosphatidylcholine (LPC) in NAR HDL has been attributed to high plasma LCAT activity. We show here that, as compared with Spr...

journal_title：Lipids

authors： Catanozi S,Rocha JC,Passarelli M,Mesquita CH,Suguiama VY,Guzzo ML,dos Santos Filho A,Quintão EC,Nakandakare ER

更新日期：2006-07-01 00:00:00

abstract：:The tissue distribution of newly synthesized 22:6n-3 and intermediate PUFA was examined in rainbow trout to further our understanding of the metabolism of this EFA in fish. Rainbow trout were fed a pulse of deuterated linolenic acid (D5-17,17,18,18,18-18:3n-3), and the tissue distribution of deuterated anabolites was ...

journal_title：Lipids

authors： Bell MV,Dick JR,Porter AE

更新日期：2003-09-01 00:00:00

abstract：:Hempseed products represent potential alternative feed ingredients for poultry. However, their usage is not currently approved due to a lack of data to support their safety and efficacy. In this regard, the current study was conducted to assess the impact of dietary concentration of hempseed (HS) products and duration...

journal_title：Lipids

authors： Neijat M,Suh M,Neufeld J,House JD

更新日期：2016-05-01 00:00:00

abstract：:Separation of thecis- andtrans-isomers of 1,2-benzylidene glyceryl esters has not yet been achieved by column or gas liquid chromatography. However these isomers were separated by thin layer chromatography in the present study and the parent cyclic alcohols regenerated by alkaline hydrolysis. ...

journal_title：Lipids

authors： Johnson CB

更新日期：1973-08-01 00:00:00

abstract：:A ubiquitously expressed member of the cytochrome P450 superfamily, CYP51, encodes lanosterol 14alpha-demethylase, the first step in the conversion of lanosterol into cholesterol in mammals. The biosynthetic intermediates of lanosterol 14alpha-demethylation are oxysterols, which inhibit HMG-CoA reductase and sterol sy...

journal_title：Lipids

authors： Gibbons GF

更新日期：2002-12-01 00:00:00

abstract：:Levels of serum lipids and lipoproteins, and the fatty acid composition of plasma phospholipids, were measured in two genetically comparable, but widely separated, populations. The 1975 mortality rates for ischemic heart disease were significantly higher in one of these populations, the Manitoban residents of pure Ice...

journal_title：Lipids

authors： Skúladóttir GV,Gudmundsdóttir S,Olafsson GB,Sigurdsson SB,Sigfússon N,Axelsson J

更新日期：1995-07-01 00:00:00

abstract：:The growing prevalence of childhood obesity has become a serious health problem over the past few decades. Although the immune system is greatly affected by childhood obesity, whether obesity influences the T cell development in the thymus is poorly understood. In this study, we used a high-fat diet (HFD)-induced obes...

journal_title：Lipids

authors： Li H,Wetchapinant C,Zhang L,Wu K

更新日期：2020-01-01 00:00:00

abstract：:The all-cis-5,9,12-heptadecatrienoic acid was identified in the cellular slime mold Polysphondylium pallidum. The structural elucidation was accomplished by capillary gas chromatography, argentation thin-layer chromatography, and gas chromatography/mass spectrometry. This fatty acid has not been reported previously. ...

journal_title：Lipids

authors： Saito T,Ochiai H

更新日期：1996-04-01 00:00:00

abstract：:The phospholipid composition of gill tissue from thermally acclimated rainbow trout, Salmo gairdneri, was determined by Iatroscan analysis following an initial development of the chromarods in a non-polar solvent to remove neutral lipids. Standard curves for all phospholipids, although linear through most of the conce...

journal_title：Lipids

authors： Hazel JR

更新日期：1985-08-01 00:00:00

abstract：:Saccharomyces cerevisiae cells were demonstrated to contain lysophosphatidylcholine (lysoPtdCho) acyltransferase (E.C. 2.3.1.23) activity. The enzyme displayed Km(app) of 69 microM for lysoPtdCho and 152 microM for oleoyl CoA. Enzyme activity was not affected by the addition of 1 mM Mg2+, Mn2+, Ca2+, or 200 mM EDTA. H...

journal_title：Lipids

authors： Richard MG,McMaster CR

更新日期：1998-12-01 00:00:00

abstract：:Chloroquine is shown to be a potent inhibitor of cholesterol biosynthesis by isolated rat hepatocytes. Half-maximal inhibition of cholesterogenesis occurs at ca. 10 micro M chloroquine. Chloroquine does not affect fatty acid synthesis by isolated hepatocytes. This suggests that chloroquine acts on the cholesterol bios...

journal_title：Lipids

authors： Beynen AC,van der Molen AJ,Geelen MJ

更新日期：1981-06-01 00:00:00

abstract：:Serum high density lipoprotein is increasingly recognized as a negative risk for cardiovascular disease. The distribution and interrelationship of serum lipids, lipoproteins, anthropometric measurements and blood pressures were determined in some 5,000 children. Children had mean +/- S.D. alpha-lipoprotein cholesterol...

journal_title：Lipids

authors： Berenson GS,Srinivasan SR,Frerichs RR,Webber LS

更新日期：1979-01-01 00:00:00

abstract：:Lipases catalyze the hydrolysis and synthesis of triglycerides and their reactions are widely used in industry. The use of ionic liquids has been explored in order to improve their catalytic properties. However, the effect of these compounds on kinetic parameters of lipases has been poorly understood. A study of the k...

journal_title：Lipids

authors： Muñoz PA,Correa-Llantén DN,Blamey JM

更新日期：2015-01-01 00:00:00

abstract：:Lipids were extracted from four dog adipose tissue sites, perirenal, pericardial, inguinal subcutaneous, and mesenteric. The triglycerides were purified by thin-layer chromatography and the sub-classes separated by silver nitrate-silica gel plates. Gas chromatography was used to delineate the fatty acid composition of...

journal_title：Lipids

authors： Gold M

更新日期：1968-11-01 00:00:00

abstract：:The lipid quality of ruminant products is largely determined by the extent of rumen microbial biohydrogenation (BH) of polyunsaturated fatty acids (FAs) and the substances formed thereby. In vitro batch incubations with mixed rumen bacteria were tracked over 24 h to characterize the profiles and kinetics of the BH pro...

journal_title：Lipids

authors： Jouany JP,Lassalas B,Doreau M,Glasser F

更新日期：2007-04-01 00:00:00

abstract：:Exercise training not only improves the plasma lipid profile but also reduces risk of developing coronary heart disease. We investigate whether plasma lipids and high density lipoprotein (HDL) metabolism are affected by aerobic training and whether the high-density lipoprotein cholesterol (HDL-C) levels at baseline in...

journal_title：Lipids

authors： da Silva JL,Maranhão RC,Silva MSM,Dias RG,Freitas FR,Bolani W,Lemos Junior JR,Alves CR,Oliveira PA,Alves GB,Oliveira EM,Negrao CE,Krieger JE,Pereira AC,Silva GA,Souza JP,Vinagre CGC

更新日期：2019-06-01 00:00:00

abstract：:The anesthetic potency of four derivatives of n-octane was measured by tadpole righting reflex and expressed as effective millimolar concentration of drug in membrane, EDM50. Potency diminished (ED50 increased) in this order: 1-octanol, EDM50 = 5.5; 1-(2-methoxyethoxy)octane, EDM50 = 28; 1-methoxyoctane, EDM50 = 61; a...

journal_title：Lipids

authors： Brockerhoff H,Brockerhoff S,Box LL

更新日期：1986-06-01 00:00:00

abstract：:The physiological role of long-chain fatty acyl-CoA is thought to be primarily in intermediary metabolism of fatty acids. However, recent data show that nM to microM levels of these lipophilic molecules are potent regulators of cell functions in vitro. Although long-chain fatty acyl-CoA are present at several hundred ...

journal_title：Lipids

authors： Gossett RE,Frolov AA,Roths JB,Behnke WD,Kier AB,Schroeder F

更新日期：1996-09-01 00:00:00

abstract：:Neutrophils play a major role in inflammation by releasing large amounts of reactive oxygen species (ROS) produced by NADPH oxidase (NOX) and myeloperoxidase (MPO). This ROS overproduction is mediated by phosphorylation of the NOX subunits in an uncontrolled manner. Therefore, targeting neutrophil subunits would repre...

journal_title：Lipids

authors： Liu M,Boussetta T,Makni-Maalej K,Fay M,Driss F,El-Benna J,Lagarde M,Guichardant M

更新日期：2014-01-01 00:00:00

abstract：:Liver fatty-acid-binding protein (FABP1, L-FABP) is the major cytosolic binding/chaperone protein for both precursor arachidonic acid (ARA) and the endocannabinoid (EC) products N-arachidonoylethanolamine (AEA) and 2-arachidonoylglycerol (2-AG). Although FABP1 regulates hepatic uptake and metabolism of ARA, almost not...

journal_title：Lipids

authors： McIntosh AL,Huang H,Landrock D,Martin GG,Li S,Kier AB,Schroeder F

更新日期：2018-06-01 00:00:00

abstract：:The pyrrolidide and picolinyl ester derivatives of the fatty acids in two natural lipid samples rich in unsaturated fatty acids, pig testis lipids and cod liver oil were satisfactorily resolved on capillary columns of fused silica coated with stationary phases of varying polarity. The picolinyl esters, in particular, ...

journal_title：Lipids

authors： Christie WW,Brechany EY,Johnson SB,Holman RT

更新日期：1986-10-01 00:00:00

abstract：:The oxidation of free DHA, DHA mixed with PC, and DHA incorporated into PC, PE, or TG was evaluated to determine which lipid provided DHA with the best protection against oxidation. DHA was either situated at the sn-1 position, sn-2 position, or both positions of the phospholipid, whereas the TG contained DHA at all p...

journal_title：Lipids

authors： Lyberg AM,Fasoli E,Adlercreutz P

更新日期：2005-09-01 00:00:00

abstract：:The hypolipidemic drug clofibrate is known to affect the hepatic transport of various organic anions including bilirubin, fatty acids and sulfobromophthalein. Changes in the rate of metabolism and/or intracellular transport have been claimed responsible for the effect. To evaluate these possibilities, the transport of...

journal_title：Lipids

authors： Sorrentino D,Weisiger RA,Bass NM,Licko V

更新日期：1989-05-01 00:00:00

abstract：:Fatty acid compositions of polar lipids and triacylglycerols isolated from eggs of the sea urchin, Arbacia punctulata, were examined before and 15 min after insemination. The main fatty acids present in polar lipids and triacylglycerols were palmitate, palmitoleate, eicosaenoate, arachidonate and eicosapentaenoate, wh...

journal_title：Lipids

authors： Metzman MS,Mastroianni A,Strauss JF

更新日期：1978-11-01 00:00:00

abstract：:A new method of isoelectric focusing (IEF) and pH gradient electrophoresis, using thin layers of agarose gel beads, was devised to investigate chylomicrons and very low density lipoproteins (VLDL). pH gradient stability and cathodal gradient drift were similar to those of polyacrylamide gel IEF, and linearity of gradi...

journal_title：Lipids

authors： Vost A,Pocock DM,Pleet S

更新日期：1979-10-01 00:00:00

abstract：:The aim of this study was to determine the fatty acid composition and trans fatty acid and fatty acid contents of breast milk in Turkish women and to find the effect of breastfeeding mothers' diet on trans fatty acid and fatty acid composition. Mature milk samples obtained from 50 Turkish nursing women were analyzed. ...

journal_title：Lipids

authors： Samur G,Topcu A,Turan S

更新日期：2009-05-01 00:00:00

abstract：:The Hordaland Homocysteine Study is a population-based screening of total plasma homocysteine (tHcy) in approximately 18,000 men and women aged 40-67 yr that took place in 1992-1993 in the county of Hordaland in Western Norway. In this cohort, tHcy was associated with several physiologic and life-style factors, includ...

journal_title：Lipids

authors： Ueland PM,Nygård O,Vollset SE,Refsum H

更新日期：2001-01-01 00:00:00

abstract：:The biosynthesis of [14C] CDP-diglyceride was studied using rat liver microsomes which were endogenously labeled with [14C] phosphatidic acid by preincubation of unlabeled microsomes with sn-[14C] glycerol-3-phosphate and appropriate cofactors. The formation of CDP-diglyceride from radioactive phosphatidate showed an ...

journal_title：Lipids

authors： Holub BJ,Piekarski J

更新日期：1976-04-01 00:00:00

abstract：:1,2-Diacylglycerol, which has been recognized as one of the intracellular second messengers, was measured quantitatively in the lipid extract from rat hearts using the thin layer chromatography and flame ionization detection (TLC/FID) method. Cholesterol acetate was added to the tissue as an internal standard, and the...

journal_title：Lipids

authors： Okumura K,Hashimoto H,Ito T,Ogawa K,Satake T

更新日期：1988-03-01 00:00:00

abstract：:The permeability of an N-oleoyldihydrosphingomyelin bilayer against glycerol was similar to that of a bilayer of phosphatidylcholine with identical effective hydrophobic chain length. Cholesterol at 1:1 molar ratio reduced the permeability, and also reduced the energy of activation of glycerol penetration, an effect n...

journal_title：Lipids

authors： Tirri LJ,Ayengar NK,Lipton LC,Chatterjie N,Brockerhoff H

更新日期：1978-04-01 00:00:00