Identification of a novel all-cis-5,9,12-heptadecatrienoic acid in the cellular slime mold Polysphondylium pallidum.

abstract：:Yeast mutant strains auxotrophic for ergosterol and blocked in mevalonate diphosphate decarboxylase (erg19) and farnesyl diphosphate (FPP) synthetase (erg20) were isolated. The main feature of the mutants blocked in FPP synthetase is their ability to excrete prenyl alcohols, such as geraniol and farnesol. The isolatio...

journal_title：Lipids

authors： Chambon C,Ladeveze V,Servouse M,Blanchard L,Javelot C,Vladescu B,Karst F

更新日期：1991-08-01 00:00:00

abstract：:The incorporation of arachidonic acid (AA) as compared to eicosapentaenoic acid (EPA) into human platelet phospholipids was tested by incubating washed platelets with a known mixture of [3H]AA and [14C]EPA. Following incubation, the platelet lipids were extracted, the individual phospholipids--phosphatidylcholine (PC)...

journal_title：Lipids

authors： Weaver BJ,Holub BJ

更新日期：1985-11-01 00:00:00

abstract：:Omega-3 (n-3) long-chain polyunsaturated fatty acids (LC-PUFA) are essential components of the diet of all vertebrates. The major dietary source of n-3 LC-PUFA for humans has been fish and seafood but, paradoxically, farmed fish are also reliant on marine fisheries for fish meal and fish oil (FO), traditionally major ...

journal_title：Lipids

authors： Betancor MB,Sprague M,Montero D,Usher S,Sayanova O,Campbell PJ,Napier JA,Caballero MJ,Izquierdo M,Tocher DR

更新日期：2016-10-01 00:00:00

abstract：:A sucrose-rich diet (SRD) induces insulin resistance and dyslipidemia with impaired hepatic glucose production and gluconeogenesis, accompanied by altered post-receptor insulin signaling steps. The aim of this study was to examine the effectiveness of fish oil (FO) to reverse or improve the impaired hepatic glucose me...

journal_title：Lipids

authors： Hein GJ,Chicco A,Lombardo YB

更新日期：2012-02-01 00:00:00

abstract：:The effect of apo very low density lipoprotein (apo VLDL) and apoprotein C-II on the phospholipase A1 activity associated with lipoprotein lipase (E.C.3.1.1.3) was studied using purified bovine milk lipoprotein lipase. The enzyme degraded 14C phosphatidylcholine (PC) to 14C 2-acyl lysophosphatidylcholine at a rate of ...

journal_title：Lipids

authors： Stocks J,Galton DJ

更新日期：1980-03-01 00:00:00

abstract：:Previous studies from our laboratory have shown that retinitis pigmentosa (RP), a family of hereditary retinal degenerations, is often accompanied by abnormal levels of cholesterol or polyunsaturated fatty acids. The requirement of the retina for n-3 fatty acids is well known, and a defect in the supply of these lipid...

journal_title：Lipids

authors： Huq L,McLachlan T,Hammer HM,Bedford D,Packard CJ,Shepherd J,Converse CA

更新日期：1993-11-01 00:00:00

abstract：:The objective of this study was to establish the impact of caloric restriction on high fat diet-induced alterations on regulators of skeletal muscle growth. We hypothesized that caloric restriction would reverse the negative effects of high fat diet-induced obesity on REDD1 and mTOR-related signaling. Following an ini...

journal_title：Lipids

authors： Dungan CM,Li J,Williamson DL

更新日期：2016-08-01 00:00:00

abstract：:The beta-adrenergic system in cardiac muscle cells is influenced by the n-3 polyunsaturated fatty acid (PUFA) content in cell membranes. This study deals with the specific effect of docosahexaenoic acid (DHA) as compared to other n-3 PUFA, without modification of the arachidonic acid content. Increasing the DHA conten...

journal_title：Lipids

authors： Grynberg A,Fournier A,Sergiel JP,Athias P

更新日期：1996-03-01 00:00:00

abstract：:In a search for a preferred source of gamma-linolenic (all-cis-6,9,12-octadecatrienoic) acid, seed oils of 33 species of Boraginaceae were examined. The desired triene was found primarily in the subfamily Boraginoideae in amounts ranging from 0.2 to 18%. Oils of this subfamily also contain 0.2 to 15% of the tetraene, ...

journal_title：Lipids

authors： Miller RW,Earle FR,Wolff IA,Barclay AS

更新日期：1968-01-01 00:00:00

abstract：:Bile acid contents were determined for isolated rat hepatocytes. During the course of isolating the hepatocytes, perfusion of rat liver with buffer containing 2% albumin eluted a significant amount of bile acids. The elution was proportional to the volume of the buffer and attributable to albumin in the buffer. The is...

journal_title：Lipids

authors： Hashimoto S,Uchida K,Hirata M

更新日期：1982-03-01 00:00:00

abstract：:The subcellular distribution of the enzymes of triacylglycerol biosynthesis has been studied in developing oilseed rape. All in vitro enzymatic activities from oleoyl-CoA to triacylglycerol were sufficient to account for the known rate of oleate deposition in triacylglycerol in vivo. The enzymatic activities from oleo...

journal_title：Lipids

authors： Murphy DJ

更新日期：1988-03-01 00:00:00

abstract：:New methods and analytical approaches are important to challenge and/or validate established beliefs in any field including the metabolism of polyunsaturated fatty acids (PUFA; polyunsaturates). Four methods that have recently been applied toward obtaining a better understanding of the homeostasis of PUFA include the ...

journal_title：Lipids

authors： Cunnane SC

更新日期：2001-09-01 00:00:00

abstract：:We evaluated whether CETP and LCAT gene polymorphisms are statistically associated with the high-density lipoprotein (HDL) size distribution, the cholesterol level of HDL subclasses, and the acute coronary syndrome (ACS) susceptibility. Two CETP gene polymorphisms (rs4783961 and rs708272) and one LCAT polymorphism (rs...

journal_title：Lipids

authors： Vargas-Alarcon G,Perez-Mendez O,Herrera-Maya G,Garcia-Sanchez C,Martinez-Rios MA,Peña-Duque MA,Posadas-Sanchez R,Posadas-Romero C,Escobedo G,Fragoso JM

更新日期：2018-02-01 00:00:00

abstract：:Sphingomyelin was isolated from cysts of the brine shrimp Artemia franciscana using QAE-Sephadex A25, Florisil and Iatrobeads column chromatographies. The chemical structure was identified using thin-layer chromatography, gas-liquid chromatography, infrared spectroscopy and matrix-assisted laser desorption ionization ...

journal_title：Lipids

authors： Kojima H,Inoue T,Sugita M,Itonori S,Ito M

更新日期：2010-07-01 00:00:00

abstract：:The molecular species of sphingoid bases were tagged with the fluorescent amino group reagent, 4-fluoro-7-nitrobenzofurazan (NBD-F). The NBD-sphingoid bases were analyzed by a highly selective and sensitive liquid chromatography-electrospray ionization tandem mass spectrometry (LC-ESI-MS/MS) technique capable of relia...

journal_title：Lipids

authors： Ishikawa T,Imai H,Maki KY

更新日期：2014-03-01 00:00:00

abstract：:Palm oil is one of the most important edible oils in the world. Its composition (rich in palmitate and oleate) make it suitable for general food uses but its utility could be increased if its fatty acid quality could be varied. In this study, we have modified a palm olein fraction by transesterification with the n-3 p...

journal_title：Lipids

authors： Zainal Z,Longman AJ,Hurst S,Duggan K,Hughes CE,Caterson B,Harwood JL

更新日期：2009-07-01 00:00:00

abstract：:Ceramides are a family of signalling lipids with diverse physiological functions that include pro-differentiative and pro-apoptotic signalling. Ceramides and their derivatives are major constituents of myelin, maintaining neuronal conductivity. Ceramides are synthesized by ceramide synthases, of which there are six is...

journal_title：Lipids

authors： Couttas TA,Lim XY,Don AS

更新日期：2015-01-01 00:00:00

abstract：:Accurate quantification of the major classes and subfractions of human serum lipoproteins is an important analytical need in the characterization and evaluation of therapy of lipid and lipoprotein abnormalities. For calibrating the analytic ultracentrifuge (AnUC), we routinely use a Beckman calibration wedge cell with...

journal_title：Lipids

authors： Kahlon TS,Adamson GL,Glines LA,Lindgren FT,Laskaris MA,Shore VG

更新日期：1984-07-01 00:00:00

abstract：:Human chylomicron triglyceride (TG) kinetics has been difficult to determine directly owing to technical limitations. This report describes a new method for studying chylomicron metabolism. Healthy volunteers (n = 10) sipped a drink providing 175 mg fat x kg(-1) h(-1) for 7.5 h to produce a steady-state chylomicronemi...

journal_title：Lipids

authors： Park Y,Damron BD,Miles JM,Harris WS

更新日期：2001-02-01 00:00:00

abstract：:Three groups of male rats were fed either a corn oil-enriched diet (17%, w/w), a salmon oil-enriched diet (12.5%) supplemented with corn oil (4.5%) or a low-fat diet (4.4%) for eight wk to investigate the possible relationships between dietary fatty acids and lipid composition, and prostaglandin E2 level and phospholi...

journal_title：Lipids

authors： Grataroli R,Léonardi J,Charbonnier M,Lafont R,Lafont H,Nalbone G

更新日期：1988-07-01 00:00:00

abstract：:This study examined the effects of sesamin inclusion in vegetable oil-based diets fed to Atlantic salmon (Salmo salar L.). The diets used differed in n-6/n-3 fatty acid (FA) ratio (0.5 and 1) and sesamin content (high 5.8 g/kg, low 1.16 g/kg and no sesamin). The oils used in the feeds were a mixture of rapeseed, linse...

journal_title：Lipids

authors： Schiller Vestergren A,Wagner L,Pickova J,Rosenlund G,Kamal-Eldin A,Trattner S

更新日期：2012-09-01 00:00:00

abstract：:Recently, a new assay method that can quantify the singlet oxygen-absorption capacity (SOAC) of antioxidants (AO) and food extracts in homogeneous organic solvents has been proposed. In the present study, second-order rate constants (kQ ) for the reaction of singlet oxygen (1 O2 ) with vitamin E homologs (α-, β-, γ-, ...

journal_title：Lipids

authors： Mukai K,Ishikawa E,Ouchi A,Nagaoka SI,Abe K,Suzuki T,Izumisawa K

更新日期：2018-06-01 00:00:00

abstract：:This study analyses the effects of dietary lipid level and source on lipid absorption and metabolism in Senegalese sole (Solea senegalensis). Juvenile fish were fed 4 experimental diets containing either 100 % fish oil (FO) or 25 % FO and 75 % vegetable oil (VO; rapeseed, linseed and soybean oils) at two lipid levels ...

journal_title：Lipids

authors： Bonacic K,Estévez A,Bellot O,Conde-Sieira M,Gisbert E,Morais S

更新日期：2016-01-01 00:00:00

abstract：:Material dealing with the chemistry, biochemistry, and biological activities of oxysterols is reviewed for the period 1987-1995. Particular attention is paid to the presence of oxysterols in tissues and foods and to their physiological relevance. ...

journal_title：Lipids

authors： Smith LL

更新日期：1996-05-01 00:00:00

abstract：:The effect of a saturated fat diet on the apoprotein composition and radioiodination properties of plasma very low density lipoprotein (VLDL) was studied in rats. After feeding the diet for 10 days, the proportion of 125I attached to VLDL lipid decreased from 50% (control animals) to 8%, the remainder (92%) being boun...

journal_title：Lipids

authors： Poulis P,Fidge NH

更新日期：1977-03-01 00:00:00

abstract：:Several experimental approaches were used to determine whether rat liver and testes express an acyl-CoA-dependent delta8 desaturase. When [1-14C]5,11,14-eicosatrienoic acid was injected via the tail vein, or directly into testes, it was incorporated into liver and testes phospholipids, but it was not metabolized to ot...

journal_title：Lipids

authors： Chen Q,Yin FQ,Sprecher H

更新日期：2000-08-01 00:00:00

abstract：:Although hypocholesterolemia is a reported finding in sickle cell disease (SCD), low-density lipoprotein (LDL)/high-density lipoprotein (HDL) subfractions and HDL-associated enzymes have not been determined in SCD patients. Blood was collected from 38 hemoglobin (Hb)A volunteers and 45 homozygous HbSS patients who had...

journal_title：Lipids

authors： Ozturk OH,Can Y,Yonden Z,Motor S,Oktay G,Kaya H,Aslan M

更新日期：2013-12-01 00:00:00

abstract：:Sterols, which are biosynthesized via the cytoplasmic mevalonate (MVA) pathway, are important structural components of the plasma membrane and precursors of steroid hormones in both vertebrates and plants. Ergosterol and cholesterol are the major sterols in yeast and vertebrates, respectively. In contrast, plants prod...

journal_title：Lipids

authors： Suzuki M,Muranaka T

更新日期：2007-02-01 00:00:00

abstract：:The kinetics of in vivo clearance of apolipoprotein (apo) A-I radioiodinated by the iodine monochloride (ICI) method of McFarlane [McFarlane, A.S. (1958) Efficient Trace-Labelling of Proteins with Iodine, Nature 182, 53] as modified by Bilheimer and co-workers [Bilheimer, D.W., Eisenberg, S., and Levy, R.I. (1972) The...

journal_title：Lipids

authors： Zhang B,Shimoji E,Tanaka H,Saku K

更新日期：2003-03-01 00:00:00

abstract：:The initial steps in the autoxidation of CLA methyl ester are poorly understood. The aim of this study was to determine the stereochemistry of the hydroperoxides formed during autoxidation of CLA methyl ester in the presence of a good hydrogen atom donor. For this purpose, 9-cis,11-trans CLA methyl ester was autoxidiz...

journal_title：Lipids

authors： Hämäläinen TI,Sundberg S,Hase T,Hopia A

更新日期：2002-06-01 00:00:00