Activation of the phospholipase A1 activity of lipoprotein lipase by apoprotein C-II.

Abstract:

:The effect of apo very low density lipoprotein (apo VLDL) and apoprotein C-II on the phospholipase A1 activity associated with lipoprotein lipase (E.C.3.1.1.3) was studied using purified bovine milk lipoprotein lipase. The enzyme degraded 14C phosphatidylcholine (PC) to 14C 2-acyl lysophosphatidylcholine at a rate of 0.28 +/- 0.01 nmol/min/ml and triolein at a rate of 20.3 +/- 0.4 nmol/min/ml in mixed emulsions of PC and triolein. The phospholipase activity and triacylglycerol lipase activity were both increased by the addition of apo VLDL and apoprotein C-II. After maximal activation, the rate of PC degradation was 1.19 +/- 0.02 nmol/min/ml and triolein degradation 64.4 +/- 0.4 nmol/min/ml. Activation of phospholipase A1 activity and triacylglycerol lipase activity occurred in parallel.

journal_name

Lipids

journal_title

Lipids

authors

Stocks J,Galton DJ

doi

10.1007/BF02540967

subject

Has Abstract

pub_date

1980-03-01 00:00:00

pages

186-90

issue

3

eissn

0024-4201

issn

1558-9307

journal_volume

15

pub_type

杂志文章

相关文献

LIPIDS文献大全
  • Dietary alpha-linolenic acid alters tissue fatty acid composition, but not blood lipids, lipoproteins or coagulation status in humans.

    abstract::We examined the effect of dietary alpha-linolenic acid (ALA) on the indices of lipid and coagulation status and on the fatty acid composition of serum and peripheral blood mononuclear cell (PBMNC) lipids in ten healthy men (age 21-37 yr) who consumed all their meals at the Western Human Nutrition Research Center for 1...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02536085

    authors: Kelley DS,Nelson GJ,Love JE,Branch LB,Taylor PC,Schmidt PC,Mackey BE,Iacono JM

    更新日期:1993-06-01 00:00:00

  • Proximate and fatty acid composition of some commercially important fish species from the Sinop region of the Black Sea.

    abstract::The proximate and fatty acid compositions of the commercially important fish species (Engraulis encrasicolus, Alosa alosa, Belone belone, Scorpaena porcus, Pomatomus saltatrix, Mullus barbatus) from the Sinop region of the Black Sea were examined. The fat contents ranged from 1.26% (for scorpion fish) to 18.12% (for s...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/s11745-012-3658-1

    authors: Kocatepe D,Turan H

    更新日期:2012-06-01 00:00:00

  • An in vitro method for studying the proliferation and differentiation of Atlantic salmon preadipocytes.

    abstract::The aim of the present study was to develop a cell culture system for studying the proliferation and differentiation of preadipocytes isolated from Atlantic salmon adipose tissue. The expression of proliferating cell nuclear antigen (PCNA) was used as a marker for cell proliferation. The cells started to proliferate w...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/s11745-003-1063-3

    authors: Vegusdal A,Sundvold H,Gjøen T,Ruyter B

    更新日期:2003-03-01 00:00:00

  • Influence of hypo- and hyperthyroidism on rat liver glycerophospholipid metabolism.

    abstract::The effects of hyper- and hypothyroidism on enzyme activities involved in phospholipid metabolism in the rat liver were studied. Hyperthyroidism significantly decreases activities of both microsomal acyl-CoA:glycero-3-phosphate acyltransferase (GPAT) (34%, p less than 0.01) and microsomal acyl-CoA:1-acylglycero-3-phos...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02534774

    authors: Dang AQ,Faas FH,Carter WJ

    更新日期:1985-12-01 00:00:00

  • Docosahexaenoic Acid Incorporation Is Not Affected by Doxorubicin Chemotherapy in either Whole Cell or Lipid Raft Phospholipids of Breast Cancer Cells in vitro and Tumor Phospholipids in vivo.

    abstract::To better understand how docosahexaenoic acid (DHA) improves the effects of doxorubicin (DOX), we examined DHA ± DOX on changes in whole cell and lipid raft phospholipids (PL) of MDA-MB-231 and MCF-7 breast cancer cells. We sought to confirm whether the relative changes in PL DHA content of MDA-MB-231 cells could be e...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1002/lipd.12252

    authors: Newell M,Patel D,Goruk S,Field CJ

    更新日期:2020-09-01 00:00:00

  • Effect of lactation on lipolysis in rat adipose tissue.

    abstract::The concentrations of nonesterified fatty acids and glycerol in rat parametrial adipose tissue increased at peak lactation. Adipose tissue from lactating rats showed higher rates of release of nonesterified fatty acids and glycerol when incubated in vitro than did tissue from nonlactating rats, but there was a substan...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02532850

    authors: Smith RW,Walsh A

    更新日期:1976-05-01 00:00:00

  • Glucose Uptake and Triacylglycerol Synthesis Are Increased in Barth Syndrome Lymphoblasts.

    abstract::Barth syndrome (BTHS) is an X-linked genetic disease resulting in loss of cardiolipin (Ptd2Gro). Patients may be predisposed to hypoglycemia and exhibit increases in whole-body glucose disposal rates and a higher fat mass percentage. We examined the reasons for this in BTHS lymphoblasts. BTHS lymphoblasts exhibited a ...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/s11745-017-4232-7

    authors: Mejia EM,Zinko JC,Hauff KD,Xu FY,Ravandi A,Hatch GM

    更新日期:2017-02-01 00:00:00

  • Inhibition of lymphocyte capping by fatty acids in mouse and man.

    abstract::Lipid-enriched diets have been related to a high cancer incidence in experimental animals for many years, and more recently, to assorted defects on the immune response. We investigated the effect of incubating human or murine (C3H/HEJ) lymphocytes with saturated (16:0) and unsaturated (18:1, 18:2, 18:3, 20:4) fatty ac...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02534659

    authors: Santiago-Delpín EA,Román-Franco AA,Colón JI

    更新日期:1982-10-01 00:00:00

  • Enzymatic acylation of ether and ester lysophospholipids in rat liver microsomes.

    abstract::The acylation of lysophospholipids by rat liver acyltransferases was studied. A comparison between ester and ether lysophospholipids as substrates revealed large differences in substrate properties. For instance, oleic acid from oleoyl-CoA and arachidonic acid from arachidonoyl-CoA were not incorporated into 1-O-octad...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02535535

    authors: Neumüller W,Fleer EA,Unger C,Eibl H

    更新日期:1987-11-01 00:00:00

  • Impact of Fabp1 Gene Ablation on Uptake and Degradation of Endocannabinoids in Mouse Hepatocytes.

    abstract::Liver fatty-acid-binding protein (FABP1, L-FABP) is the major cytosolic binding/chaperone protein for both precursor arachidonic acid (ARA) and the endocannabinoid (EC) products N-arachidonoylethanolamine (AEA) and 2-arachidonoylglycerol (2-AG). Although FABP1 regulates hepatic uptake and metabolism of ARA, almost not...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1002/lipd.12071

    authors: McIntosh AL,Huang H,Landrock D,Martin GG,Li S,Kier AB,Schroeder F

    更新日期:2018-06-01 00:00:00

  • Delayed conversion of squalene to sterols during development of Pinus pinea seeds.

    abstract::During germination of seeds of the gymnosperm, Pinus pinea, radioactivity from [2-14C]-mevalonate proceeded principally through the anaerobic reactions leading to squalene in the first 24 hr in both the haploid endosperm and the diploid embryo, and only with succeeding time (3-9 days) in both cases was label transferr...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02533642

    authors: McKean ML,Nes WR

    更新日期:1977-04-01 00:00:00

  • Changes in lipid content, fatty acid composition and lipoprotein lipase activity in dry goat omental adipose tissue according to tissue site.

    abstract::Water and lipid contents, fatty acid distribution, and lipoprotein lipase activity were determined in 11 samples taken from the Omentum Majus of five dry Alpine goats. Samples were chosen to standardize sampling sites using geometric guide marks representative of different adipose tissue sites. Sample location explain...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02536391

    authors: Bas P,Gallouin F,Morand-Fehr P

    更新日期:1992-06-01 00:00:00

  • CETP and LCAT Gene Polymorphisms Are Associated with High-Density Lipoprotein Subclasses and Acute Coronary Syndrome.

    abstract::We evaluated whether CETP and LCAT gene polymorphisms are statistically associated with the high-density lipoprotein (HDL) size distribution, the cholesterol level of HDL subclasses, and the acute coronary syndrome (ACS) susceptibility. Two CETP gene polymorphisms (rs4783961 and rs708272) and one LCAT polymorphism (rs...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1002/lipd.12017

    authors: Vargas-Alarcon G,Perez-Mendez O,Herrera-Maya G,Garcia-Sanchez C,Martinez-Rios MA,Peña-Duque MA,Posadas-Sanchez R,Posadas-Romero C,Escobedo G,Fragoso JM

    更新日期:2018-02-01 00:00:00

  • The effect of conjugated linoleic acid isomers on fatty acid profiles of liver and adipose tissues and their conversion to isomers of 16:2 and 18:3 conjugated fatty acids in rats.

    abstract::Conjugated linoleic acid (CLA) is a collective term that describes different isomers of linoleic acid with conjugated double bonds. Although the main dietary isomer is 9cis,11trans-18:2, which is present in dairy products and ruminant fat, the biological effects of CLA generally have been studied using mixtures in whi...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/s11745-001-0759-8

    authors: Sébédio JL,Angioni E,Chardigny JM,Grégoire S,Juanéda P,Berdeaux O

    更新日期:2001-06-01 00:00:00

  • Rapid determination of double-bond positions in monoenoic fatty acids by periodate-permanganate oxidation.

    abstract::Tetramethylammonium hydroxide has been used in the extraction and pyrolysis methylation of the carboxylic acids produced by periodate-permanganate oxidation of monounsaturated fatty acid methyl esters. This modification of the von Rudloff procedure allows rapid determination of double-bond positions and analysis of mi...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02530977

    authors: Downing DT,Greene RS

    更新日期:1968-01-01 00:00:00

  • Lipid and fatty acid compositions of a novel docosahexaenoic acid-producing marine bacterium.

    abstract::An unidentified bacterial strain, SCRC-21406, isolated from the intestine of a marine fish, Glossanodon semifasciatus, produced docosahexaenoic acid at 23% (mol/mol) [= 28% (w/w)] of total fatty acids in a medium containing 0.5% (wt/vol) peptone and 0.1% (wt/vol) yeast extract at 12 degrees C under atmospheric pressur...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/s11745-997-0127-8

    authors: Watanabe K,Ishikawa C,Ohtsuka I,Kamata M,Tomita M,Yazawa K,Muramatsu H

    更新日期:1997-09-01 00:00:00

  • Comparison of RRR-alpha- and all-rac-alpha-tocopherol uptake by permanent rat skeletal muscle myoblasts (L6 cells): effects of exogenous lipoprotein lipase.

    abstract::The purpose of the present investigation was to test whether permanent skeletal muscle cells (rat L6 cells) could serve as an in vitro model for alpha-tocopherol (alphaTocH) biodiscrimination studies. L6 cells were incubated in the presence of high density lipoprotein (HDL), low density lipoprotein (LDL), and very low...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/s11745-998-0298-3

    authors: Nakamura T,Reicher H,Sattler W

    更新日期:1998-10-01 00:00:00

  • Working with Randy: The Diacylglycerol Acyltransferase Story.

    abstract::Vegetable oils are one of the main agricultural commodities. Demand has been increasing steadily over the last five decades and, with finite land available, it is vital that we increase productivity. My laboratory has focused on the regulation of plant lipid metabolism and, as part of this work, we identified diacylgl...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1002/lipd.12267

    authors: Harwood JL

    更新日期:2020-09-01 00:00:00

  • Involvement of phospholipids in apolipoprotein B modification during low density lipoprotein oxidation.

    abstract::An increased amount of phospholipids remained attached on delipidated apolipoprotein B originated from oxidized low density lipoprotein (LDL). 31P nuclear magnetic resonance analysis of such apolipoprotein showed an organic phosphorus peak at -0.55 ppm, which suggests the formation of adducts (most probably Schiff bas...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/s11745-998-0318-3

    authors: Karakatsani AI,Liapikos TA,Troganis AN,Tsoukatos DC

    更新日期:1998-12-01 00:00:00

  • Stereospecific analysis of triacylglycerols rich in long-chain polyunsaturated fatty acids.

    abstract::Six oils of marine, algal, and microbial origin were analyzed for stereospecific distribution of component fatty acids. The general procedure involved preparation of sn-1,2-(2,3)-diacylglycerols by partial deacylation with ethylmagnesium bromide or pancreatic lipase, separation of X-1,3- and sn-1,2(2,3)-diacylglycerol...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02522622

    authors: Myher JJ,Kuksis A,Geher K,Park PW,Diersen-Schade DA

    更新日期:1996-02-01 00:00:00

  • Chemical composition of subcellular particles from cultured cells of human tissue.

    abstract::Chemical composition of subcellular components of HeLa, KB, human heart and liver tissue-culture cell lines have been studied.The concentration of RNA, protein and phospholipid (mug/mug of DNA) of total subcellular particles was similar for all four cell lines studied. The greatest RNA concentration and lowest protein...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02531999

    authors: Tsao SS,Cornatzer WE

    更新日期:1967-01-01 00:00:00

  • Formation of trimers of alpha-tocopherol and its model compound, 2,2,5,7,8-pentamethylchroman-6-ol, in autoxidizing methyl linoleate.

    abstract::The reaction products of alpha-tocopherol and its model compound, 2,2,5,7,8-pentamethylchroman-6-ol, during the autoxidation of methyl linoleate at 37 C were investigated. Two isomeric trimers were obtained as the major reaction products of alpha-tocopherol, and a trimer was obtained as that of its model chroman. The ...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02536221

    authors: Yamauchi R,Kato K,Ueno Y

    更新日期:1988-08-01 00:00:00

  • Nonmembrane associated dolichol in rat liver.

    abstract::The distribution of dolichol in rat liver was studied. Upon high-speed centrifugation, 9% of the total tissue dolichol was recovered in the supernatant. Dolichol was enclosed in vesicles and in lipidic particles which were isolated by gel filtration and density gradient centrifugation. The particles had a diameter of ...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02537050

    authors: Löw P,Peterson E,Edlund C,Brunk U,Appelkvist EL

    更新日期:1992-01-01 00:00:00

  • Isoprenoid fatty acids from marine sponges. Are sponges selective?

    abstract::The burrowing sponges Anthosigmella varians and Spheciospongia vesparium were found to be rich in the isoprenoid phospholipid fatty acid 4,8,12-trimethyltridecanoic (5.2% and 23%, respectively, of the total fatty acid composition), while the burrowing sponge Chondrilla nucula and the demosponge Agelas dispar contained...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02533980

    authors: Carballeira NM,Maldonado L,Porras B

    更新日期:1987-10-01 00:00:00

  • Validation of a single-isotope-labeled cholesterol tracer approach for measuring human cholesterol absorption.

    abstract::Cholesterol absorption is frequently determined using the plasma dual stable-isotope ratio method (PDSIRM). However, this method involves intravenous injection of stable-isotope-labeled cholesterol with simultaneous oral administration of differently labeled cholesterol, which results in high study costs and involves ...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/s11745-004-1206-6

    authors: Wang Y,Vanstone CA,Parsons WD,Jones PJ

    更新日期:2004-01-01 00:00:00

  • Replacement of Marine Fish Oil with de novo Omega-3 Oils from Transgenic Camelina sativa in Feeds for Gilthead Sea Bream (Sparus aurata L.).

    abstract::Omega-3 (n-3) long-chain polyunsaturated fatty acids (LC-PUFA) are essential components of the diet of all vertebrates. The major dietary source of n-3 LC-PUFA for humans has been fish and seafood but, paradoxically, farmed fish are also reliant on marine fisheries for fish meal and fish oil (FO), traditionally major ...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/s11745-016-4191-4

    authors: Betancor MB,Sprague M,Montero D,Usher S,Sayanova O,Campbell PJ,Napier JA,Caballero MJ,Izquierdo M,Tocher DR

    更新日期:2016-10-01 00:00:00

  • Lysophosphatidic acid produced by hen egg white lysophospholipase D induces vascular development on extraembryonic membranes.

    abstract::Lysophosphatidic acid (lysoPtdOH), a lysophospholipid mediator, exerts diverse physiological effects, including angiogenesis, through its specific G-protein-coupled receptors. Previously, we showed that unfertilized hen egg white contains polyunsaturated fatty acid-rich lysoPtdOH and lysophospholipase D (lysoPLD). Her...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/s11745-013-3765-7

    authors: Morishige J,Uto Y,Hori H,Satouchi K,Yoshiomoto T,Tokumura A

    更新日期:2013-03-01 00:00:00

  • Separation and quantitation of mono-, di-, and triglycerides and free oleic acid using thin-layer chromatography with flame-ionization detection.

    abstract::alpha-Monoolein was prepared from glycidol and oleic acid by the regioselective opening of glycidol in the presence of an anionic resin. During the reaction, the lipochemical synthesis medium becomes enriched in monoolein, the effective emulsifying agent. This mixture can be analyzed by thin-layer chromatography coupl...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02522406

    authors: Peyrou G,Rakotondrazafy V,Mouloungui Z,Gaset A

    更新日期:1996-01-01 00:00:00

  • Mooreamide A: a cannabinomimetic lipid from the marine cyanobacterium Moorea bouillonii.

    abstract::Bioassay-guided fractionation of a collection of Moorea bouillonii from Papua New Guinea led to the isolation of a new alkyl amide, mooreamide A (1), along with the cytotoxic apratoxins A-C and E. The planar structure of 1 was elucidated by NMR spectroscopy and mass spectrometry analysis. Structural homology between m...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/s11745-014-3949-9

    authors: Mevers E,Matainaho T,Allara' M,Di Marzo V,Gerwick WH

    更新日期:2014-11-01 00:00:00

  • Lactation curves and effect of pup removal on milk fat of C57Bl/6J mice fed different diet fats.

    abstract::Groups of C57Bl/6J mice, fed either a cis (C-Diet) or trans diet (T-Diet) were milked without preconditioning at 6, 8, 10 and 12 days postpartum. On day 10, groups of mice were also milked 4, 6 and 18 h after separation of the pups. Except for the 18-h separation, all T-Diet fed animals produced milk of lower fat cont...

    journal_title:Lipids

    pub_type: 杂志文章

    doi:10.1007/BF02535872

    authors: Teter BB,Sampugna J,Keeney M

    更新日期:1992-11-01 00:00:00