Abstract:
:An increased amount of phospholipids remained attached on delipidated apolipoprotein B originated from oxidized low density lipoprotein (LDL). 31P nuclear magnetic resonance analysis of such apolipoprotein showed an organic phosphorus peak at -0.55 ppm, which suggests the formation of adducts (most probably Schiff bases) of oxidized phospholipids with apolipoprotein B. The above reaction occurs in parallel with the hydrolysis of oxidized phospholipids, catalyzed by the LDL-attached platelet-activating factor acetylhydrolase, and may contribute to the proatherogenic effect of oxidatively modified low density lipoprotein.
journal_name
Lipidsjournal_title
Lipidsauthors
Karakatsani AI,Liapikos TA,Troganis AN,Tsoukatos DCdoi
10.1007/s11745-998-0318-3subject
Has Abstractpub_date
1998-12-01 00:00:00pages
1159-62issue
12eissn
0024-4201issn
1558-9307journal_volume
33pub_type
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