alpha-Tocopherol oxidation mediated by superoxide anion (O2-). I. Reactions in aprotic and protic conditions.

abstract：:Many reports have shown the beneficial effects of consumption of pine seeds and pine seed oil. However, few studies have examined the biological effect of pinolenic acid (PNA; 5,9,12-18:3), the main fatty acid in pine seed oil. In this study, using murine macrophage RAW264.7 cells as a model, we examined the effect of...

journal_title：Lipids

authors： Chuang LT,Tsai PJ,Lee CL,Huang YS

更新日期：2009-03-01 00:00:00

abstract：:The effects of SMP-500, a novel ACAT inhibitor, on serum lipid levels, hepatic lipid secretion rate, and hepatic lipid disposition in rats were studied to clarify its lipid-lowering action. SMP-500 reduced the serum cholesterol level in a dose-dependent manner in rats fed a hypercholesterolemic diet. SMP-500 also redu...

journal_title：Lipids

authors： Ioriya K,Nishimura T,Ohashi N

更新日期：2002-04-01 00:00:00

abstract：:The prevalence of colorectal cancer (CRC) continues to increase. Treatment of CRC remains a significant clinical challenge, and effective therapies for advanced CRC are desperately needed. Increasing attention and ongoing research efforts have focused on krill oil that may provide health benefits to the human body. He...

journal_title：Lipids

authors： Jing W,Bi Y,Wang G,Zeng S,Han L,Yang H,Wang N,Zhao Y

更新日期：2020-09-15 00:00:00

abstract：:Lutein is an oxygenated carotenoid (xanthophyll) found in dark green leafy vegetables. High intakes of lutein may lower the risk of age-related macular degeneration. Current understanding of human lutein metabolism as it might occur in vivo is incomplete. Therefore, we conducted a feasibility study where we dosed a no...

journal_title：Lipids

authors： de Moura FF,Ho CC,Getachew G,Hickenbottom S,Clifford AJ

更新日期：2005-10-01 00:00:00

abstract：:The artificial rearing model was used to investigate the effects of short-term exposure to ethanol on growth and fatty acid composition of forebrain (FB) and cerebellum (CB) during the brain growth spurt in either n-3 fatty acid-adequate (AD) or n-3 deficient (DEF) rat pups. On postnatal day 5, offspring of female rat...

journal_title：Lipids

authors： Ward GR,Xing HC,Wainwright PE

更新日期：1999-11-01 00:00:00

abstract：:This review covers the work of our laboratory on the antineoplastic activity of some ether lipids and derivatives that are related to platelet-activating factor (PAF). Various 1-O-alkyl lysophospholipid derivatives (ALP) show therapeutic activity in mouse transplant tumor models and in metastatic 3-Lewis lung carcinom...

journal_title：Lipids

authors： Berdel WE

更新日期：1987-11-01 00:00:00

abstract：:The n-6 and n-3 fatty acid status of developing organs is the cumulative result of the diet lipid composition and many complex events of lipid metabolism. Little information is available, however, on the potential effects of the saturated fatty acid chain length (8:0-16:0) or oleic acid (18:1) content of the diet on t...

journal_title：Lipids

authors： Wall KM,Diersen-Schade D,Innis SM

更新日期：1992-12-01 00:00:00

abstract：:The effectiveness of different fatty acids as inhibitors of fatty acyl delta 5 desaturation activity in human skin fibroblasts has been investigated. When incubated with 2.25 microM [14C] eicosatrienoate (20:3 omega 6) in otherwise lipid-free medium, these cells rapidly incorporate the radiolabeled fatty acid into cel...

journal_title：Lipids

authors： Rosenthal MD,Doloresco MA

更新日期：1984-11-01 00:00:00

abstract：:The degradation of exogenous radioactively labeled fatty acids by 5-day-old barley shoots was examined. [1-(14)C] Linoleic acid was observed to be degraded 7 times faster than [1-(14)C] oleic acid and 5 times faster than [1-(14)C] palmitic acid. The pathway of degradation was determined by identifying the water-solubl...

journal_title：Lipids

authors： Nabors LA,Morgan MS,Newman DW,Jaworski JG

更新日期：1984-07-01 00:00:00

abstract：:Orally administered dihomo-gamma-linolenic acid (DHLA) is well absorbed in man; it appears in blood after ca. 4 hr first as triglyceride ester and later as phospholipid. After sustained-dosing, DHLA penetrated membrane pools and all phospholipid components but, depending on the dosage, reached a metabolic equilibrium ...

journal_title：Lipids

authors： Stone KJ,Willis AL,Hart WM,Kirtland SJ,Kernoff PB,McNicol GP

更新日期：1979-02-01 00:00:00

abstract：:The cleavage products formed by autoxidation of lycopene were evaluated in order to elucidate possible oxidation products of lycopene in biological tissues. Lycopene solubilized at 50 microM in toluene, aqueous Tween 40, or liposomal suspension was oxidized by incubating at 37 degrees C for 72 h. Among a number of oxi...

journal_title：Lipids

authors： Kim SJ,Nara E,Kobayashi H,Terao J,Nagao A

更新日期：2001-02-01 00:00:00

abstract：:The biosynthesis of 3R-hydroxy-5Z, 8Z, 11Z,14Z-eicosatetraenoic acid (3R-HETE) from arachidonic acid (20:4n-6) by the hyphal-forming yeast, Dipodascopsis uninucleata, in cell-free enzyme extracts required CoASH, ATP, NAD+ and Mg2+; 3R-HETE was present as the CoA derivative in enzyme extracts and its biosynthesis was a...

journal_title：Lipids

authors： Fox SR,Hamberg M,Friend J,Ratledge C

更新日期：2000-11-01 00:00:00

abstract：:Most CLA chicken feeding trials used cis,trans (c,t) and trans,cis (t,c) CLA isomers to produce CLA-rich eggs, while reports of trans,trans (t,t) CLA enrichment in egg yolks are limited. The CLA yolk fatty acid profile changes and the 10-12 days of feeding needed for maximum CLA are well documented, but there is no in...

journal_title：Lipids

authors： Shinn SE,Gilley AD,Proctor A,Anthony NB

更新日期：2015-04-01 00:00:00

abstract：:In a detailed sterol analysis of the marine diatom Phaeodactylum tricornutum, free sterols as well as esterified and glycosylated conjugates were found. When the alga was grown under standard conditions (i.e., at 13 degrees C under white light), 64% of total sterols were steryl glycosides. In all sterol classes, excep...

journal_title：Lipids

authors： Véron B,Billard C,Dauguet JC,Hartmann MA

更新日期：1996-09-01 00:00:00

abstract：:The effect of essential fatty acid (EFA) deficiency on rat-brain myelin proteins was studied. Rats were maintained on a lipid-free diet and compared with control rats fed the same diet supplemented with 3% corn oil. At 17 days of age, each pup was injected with [3H]leucine and rats from each group were killed over a p...

journal_title：Lipids

authors： Miller SL,Klurfeld DM,Loftus B,Kritchevsky D

更新日期：1984-06-01 00:00:00

abstract：:Recently, a new assay method that can quantify the singlet oxygen-absorption capacity (SOAC) of antioxidants (AO) and food extracts in homogeneous organic solvents has been proposed. In the present study, second-order rate constants (kQ ) for the reaction of singlet oxygen (1 O2 ) with vitamin E homologs (α-, β-, γ-, ...

journal_title：Lipids

authors： Mukai K,Ishikawa E,Ouchi A,Nagaoka SI,Abe K,Suzuki T,Izumisawa K

更新日期：2018-06-01 00:00:00

abstract：:Insulin and dietary fructose independently induce stearoyl-CoA desaturase 1 (SCD1) gene expression in diabetic mouse liver. In the present study, we again used diabetic mice and supplemented a high fructose diet with polyunsaturated fatty acids (PUFA) to determine the selective repression of SCD1 gene expression by di...

journal_title：Lipids

authors： Waters KM,Ntambi JM

更新日期：1996-03-01 00:00:00

abstract：:Dyslipoproteinemia of the Nagase analbuminemic rat (NAR) is characterized by elevated concentrations of VLDL and LDL attributed to increased rates of liver lipoprotein synthesis. Increased lysophosphatidylcholine (LPC) in NAR HDL has been attributed to high plasma LCAT activity. We show here that, as compared with Spr...

journal_title：Lipids

authors： Catanozi S,Rocha JC,Passarelli M,Mesquita CH,Suguiama VY,Guzzo ML,dos Santos Filho A,Quintão EC,Nakandakare ER

更新日期：2006-07-01 00:00:00

abstract：:De novo synthesis and mitochondrial elongation of fatty acids have been demonstrated in subcellular fractions from hog and human aorta. Microsomal fatty acid elongation has been shown in hog aorta. The activity catalyzing the formation of fatty acids from acetyl and malonyl CoA was associated with a high molecular wei...

journal_title：Lipids

authors： Slakey LL,Ferrick TJ,Ness GC,Porter JW

更新日期：1979-05-01 00:00:00

abstract：:The effect of dexamethasone on the incorporation and conversion of [1-14C]eicosa-8,11,14-trienoic acid to arachidonic acid in isolated hepatocytes and in hepatoma tissue culture (HTC) cells was studied. In both kinds of cells, no changes in the exogenous acid incorporation were found when the hormone was added to the ...

journal_title：Lipids

authors： Marra CA,de Alaniz MJ,Brenner RR

更新日期：1986-03-01 00:00:00

abstract：:Separation of thecis- andtrans-isomers of 1,2-benzylidene glyceryl esters has not yet been achieved by column or gas liquid chromatography. However these isomers were separated by thin layer chromatography in the present study and the parent cyclic alcohols regenerated by alkaline hydrolysis. ...

journal_title：Lipids

authors： Johnson CB

更新日期：1973-08-01 00:00:00

abstract：:The purpose of this study was to investigate in healthy humans the effect of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) intake, alone or in combination with dL-alpha-tocopherol acetate (vitamin E) supplements on lipid peroxidation. Eighty men were randomly assigned in a double-blind fashion to take dai...

journal_title：Lipids

authors： Allard JP,Kurian R,Aghdassi E,Muggli R,Royall D

更新日期：1997-05-01 00:00:00

abstract：:The conversion of labeled palmitic, linoleic, arachidonic and docosahexaenoic acids to their respective acyl CoA's was studied in homogenates and microsomes of rat tissues. The highest activity, both in homogenates and microsomes, was seen in liver and heart. There was moderate activity in retina, brain, lung, kidney ...

journal_title：Lipids

authors： Reddy TS,Bazan NG

更新日期：1984-12-01 00:00:00

abstract：:[1-14C]alpha-Linolenic acid was incubated with a particulate fraction of homogenate of leaves of the meadow buttercup (Ranunculus acris L.). The main product was a divinyl ether fatty acid, which was identified as 12-[1'(Z),3'(Z)-hexadienyloxy]-9(Z),11(E)-dodecadienoic acid. Addition of glutathione peroxidase and redu...

journal_title：Lipids

authors： Hamberg M

更新日期：1998-11-01 00:00:00

abstract：:Changes of lipoprotein composition have been mainly reported in conditions of sepsis. This study characterized compositional changes in LDL and HDL during the acute phase response following cardiac surgery with cardiopulmonary bypass. Twenty-one patients undergoing cardiac surgery were included in this study. Blood sa...

journal_title：Lipids

authors： Hacquebard M,Ducart A,Schmartz D,Malaisse WJ,Carpentier YA

更新日期：2007-12-01 00:00:00

abstract：:To test the effects of eicosapentaenoic acid (EPA) infusion on pulmonary edema induced by coronary ligation and reperfusion, extravascular lung water (EVLW) was measured in situ by the thermal-dye double indicator dilution method in dogs. In the control group of five dogs, 30 mL of a 10% soybean oil emulsion was infus...

journal_title：Lipids

authors： Izuoka T,Kimura Y,Hamazaki T,Tamura T,Kitashiro S,Sugiura T,Jikuhara T,Iwasaka T

更新日期：1997-01-01 00:00:00

abstract：:Membrane phospholipid (PL) composition has been shown to affect cellular function by altering membrane physical structure. The sarcolemma plasma membrane (SLpm) is integral to skeletal muscle function and health. Previous studies assessing SLpm PL composition have demonstrated contamination from transverse (t)-tubule,...

journal_title：Lipids

authors： Fajardo VA,McMeekin L,Basic A,Lamb GD,Murphy RM,LeBlanc PJ

更新日期：2013-04-01 00:00:00

abstract：:All fatty acids have important functions, but the term "essential" is applied only to those polyunsaturated fatty acids (PUFA) that are necessary for good health and cannot be completely synthesized in the body. The need for arachidonic acid, which is utilized for eicosanoid synthesis and is a constituent of membrane ...

journal_title：Lipids

authors： Spector AA

更新日期：1999-01-01 00:00:00

abstract：:Plant sterols were found by gas liquid chromatography in the sterols of five species of aquatic vertebrates; mackerel (Scomber japonicus), rainbow trout (Salmo gairdnerii), smelt (Osmerus dentex), sardine (Sardinops melanosticta) and chimera (Chimera phantasma). The sterols of chimera liver, sardine flesh and sardine ...

journal_title：Lipids

authors： Takagi T,Sakai A,Hayashi K,Itabashi Y

更新日期：1979-01-01 00:00:00

abstract：:The purpose of this study was to examine the effects of two purified isomers of CLA (c9,t11-CLA and t10,c12-CLA) on the weights and FA compositions of hepatic TG, phospholipids, cholesterol esters, and FFA. Eight-week-old female mice (n = 6/group) were fed either a control diet or diets supplemented with 0.5% c9,t11-C...

journal_title：Lipids

authors： Kelley DS,Bartolini GL,Warren JM,Simon VA,Mackey BE,Erickson KL

更新日期：2004-02-01 00:00:00