Ether lipids and analogs in experimental cancer therapy. A brief review of the Munich experience.

abstract：:The purpose of this study was to investigate in healthy humans the effect of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) intake, alone or in combination with dL-alpha-tocopherol acetate (vitamin E) supplements on lipid peroxidation. Eighty men were randomly assigned in a double-blind fashion to take dai...

journal_title：Lipids

authors： Allard JP,Kurian R,Aghdassi E,Muggli R,Royall D

更新日期：1997-05-01 00:00:00

abstract：:Changes of lipoprotein composition have been mainly reported in conditions of sepsis. This study characterized compositional changes in LDL and HDL during the acute phase response following cardiac surgery with cardiopulmonary bypass. Twenty-one patients undergoing cardiac surgery were included in this study. Blood sa...

journal_title：Lipids

authors： Hacquebard M,Ducart A,Schmartz D,Malaisse WJ,Carpentier YA

更新日期：2007-12-01 00:00:00

abstract：:The antioxidant effects of natural estrogens (estrone, E1; 17 beta-estradiol), synthetic estrogens (17 alpha-ethynylestradiol, EE2; mestranol, MES; diethylstilbestrol, DES) and catecholestrogens (2-hydroxyestradiol; 4-hydroxyestradiol, 4-OHE2) on lipid peroxidation induced by different means in rat liver microsomes we...

journal_title：Lipids

authors： Lacort M,Leal AM,Liza M,Martín C,Martínez R,Ruiz-Larrea MB

更新日期：1995-02-01 00:00:00

abstract：:In vivo intestinal perfusion was used to follow the absorption of three different choline glycerophospholipids (CGP) in guinea pig. These included 1-[3H]palmitoyl-2-acyl-sn-glycero-3-phosphocholine (diacyl-GPC), 1-[3H]-O-hexadecyl-2-acyl-sn-glycero-3-phosphocholine (alkylacyl-GPC) and 1,2-di-O-hexadecyl-sn-glycero-3-p...

journal_title：Lipids

authors： Diagne A,Mitjavila S,Fauvel J,Chap H,Douste-Blazy L

更新日期：1987-01-01 00:00:00

abstract：:Developing rat brain has the capacity for either delta 9 or delta 6 desaturation of fatty acids. In liver, evidence supports the existence of separate enzymes for each reaction, but it is not known whether in brain delta 9 or delta 6 desaturation of saturated fatty acids involves distinct enzymes. We have used fatty a...

journal_title：Lipids

authors： Cook HW

更新日期：1979-09-01 00:00:00

abstract：:Two novel lipopeptides, which have the peptide ligands [alpha-melanocyte stimulating hormone (alpha-MSH)] sequence and repeated [Gly-Arg-Gly-Asp-Se (GRGDS) sequence], are designed, synthesized by the solid-phase method, and introduced into liposome membranes by the freeze-thaw method. These liposomes bearing the pepti...

journal_title：Lipids

authors： Yagi N,Ogawa Y,Kodaka M,Okada T,Tomohiro T,Konakahara T,Okuno H

更新日期：2000-06-01 00:00:00

abstract：:Current methods for determining the regiochemistry of monoacylglycerols are lengthy, tedious and aggravated by the ready isomerization of 2-acyl-sn-glycerols. A new method employs a very rapid adsorption chromatography step in which isomerization is kept to a minimum, followed by formation of the isopropylidene deriva...

journal_title：Lipids

authors： Dawe RD,Wright JJ

更新日期：1988-04-01 00:00:00

abstract：:An improved method was developed for measuring malondialdehyde (MDA) as its thiobarbituric acid (TBA) complex. Samples were initially incubated with 1% potassium iodide and 0.1% butylated hydroxytoluene at 50 degrees C for 20 min, and then with 0.4% TBA at 60 degrees C for 60 min. The MDA-TBA complex formed was extrac...

journal_title：Lipids

authors： Li XY,Chow CK

更新日期：1994-01-01 00:00:00

abstract：:Sphingomyelin was isolated from cysts of the brine shrimp Artemia franciscana using QAE-Sephadex A25, Florisil and Iatrobeads column chromatographies. The chemical structure was identified using thin-layer chromatography, gas-liquid chromatography, infrared spectroscopy and matrix-assisted laser desorption ionization ...

journal_title：Lipids

authors： Kojima H,Inoue T,Sugita M,Itonori S,Ito M

更新日期：2010-07-01 00:00:00

abstract：:We examined growth performance and the lipid content in juvenile cobia, Rachycentron canadum, fed a taurine supplemented (1.5 %), plant protein based diet with two fish oil replacements. The first fish oil replacement was a thraustochytrid meal (TM + SOY) plus soybean oil (~9 % CL) and the second was a canola oil supp...

journal_title：Lipids

authors： Watson AM,Barrows FT,Place AR

更新日期：2013-09-01 00:00:00

abstract：:Triglycerides from normal liver, host liver, and heptoma of rats maintained on chow and fat-free diets were subjected to sterospecific analysis. Normal and host liver triglycerides from animals on the same diet did not exhibit significant differences. Fat-free diet reduced polyunsaturated fatty acids in normal and i...

journal_title：Lipids

authors： Wood R

更新日期：1975-07-01 00:00:00

abstract：:Lysophosphatidic acid (lysoPtdOH), a lysophospholipid mediator, exerts diverse physiological effects, including angiogenesis, through its specific G-protein-coupled receptors. Previously, we showed that unfertilized hen egg white contains polyunsaturated fatty acid-rich lysoPtdOH and lysophospholipase D (lysoPLD). Her...

journal_title：Lipids

authors： Morishige J,Uto Y,Hori H,Satouchi K,Yoshiomoto T,Tokumura A

更新日期：2013-03-01 00:00:00

abstract：:Oxidized low density lipoprotein (Ox-LDL) is a well-established risk factor in atherosclerosis and lysophosphatidylcholine (LysoPtdCho) is considered to be one of the major atherogenic component of Ox-LDL. The purpose of this work was to investigate the effects of two membrane n-3 long chain polyunsaturated fatty acid...

journal_title：Lipids

authors： Tardivel S,Gousset-Dupont A,Robert V,Pourci ML,Grynberg A,Lacour B

更新日期：2009-03-01 00:00:00

abstract：:Feline omental lipid extracts, previously reported to be angiogenic in the cornea of rabbits, were fractionated and the major lipid components characterized. Approximately 97% of the chloroform/methanol extract consisted of triglycerides containing primarily 16:0, 18:0, 18:1 and 18:2 fatty acids. Trace quantities of f...

journal_title：Lipids

authors： McCluer RH,Evans JE,Williams M,Griffith AL,Catsimpoolas N

更新日期：1987-04-01 00:00:00

abstract：:The biosynthesis of 3R-hydroxy-5Z, 8Z, 11Z,14Z-eicosatetraenoic acid (3R-HETE) from arachidonic acid (20:4n-6) by the hyphal-forming yeast, Dipodascopsis uninucleata, in cell-free enzyme extracts required CoASH, ATP, NAD+ and Mg2+; 3R-HETE was present as the CoA derivative in enzyme extracts and its biosynthesis was a...

journal_title：Lipids

authors： Fox SR,Hamberg M,Friend J,Ratledge C

更新日期：2000-11-01 00:00:00

abstract：:Obesity and type 2 diabetes have reached epidemic proportions in the United States. It is well-established that increasing physical activity plays an important role in reducing risk of obesity and diabetes. Few studies, however, have examined the association between sedentary behaviors such as prolonged television (TV...

journal_title：Lipids

authors： Hu FB

更新日期：2003-02-01 00:00:00

abstract：:Acetate supplementation increases plasma acetate, brain acetyl-CoA, histone acetylation, phosphocreatine levels, and is anti-inflammatory in models of neuroinflammation and neuroborreliosis. Although radiolabeled acetate is incorporated into the cellular lipid pools, the effect that acetate supplementation has on lipi...

journal_title：Lipids

authors： Bhatt DP,Rosenberger TA

更新日期：2014-07-01 00:00:00

abstract：:We have developed cultures of smooth muscle cells (SMC) isolated from arterial hypercholesterolemic chicks (cholesterol-SMC). These cultures are suitable for the study at the molecular level of the changes in arterial SMC induced by a cholesterol diet. By using a strong dose of cholesterol (5%) for 10 d, we obtained v...

journal_title：Lipids

authors： Carazo A,Alejandre J,Diaz R,Ríos A,Castillo M,Linares A

更新日期：1998-02-01 00:00:00

abstract：:Tetramethylammonium hydroxide has been used in the extraction and pyrolysis methylation of the carboxylic acids produced by periodate-permanganate oxidation of monounsaturated fatty acid methyl esters. This modification of the von Rudloff procedure allows rapid determination of double-bond positions and analysis of mi...

journal_title：Lipids

authors： Downing DT,Greene RS

更新日期：1968-01-01 00:00:00

abstract：:The use of the organic cosolvents tetrahydrofuran and dimethylsulfoxide was found to be unsuitable for prostate tumor cell cultures because of solvent cytotoxicity and the poor solubility and instability of lycopene. For example, the half-life of lycopene in organic/aqueous solution was found to be less than 2 h. Ther...

journal_title：Lipids

authors： Xu X,Wang Y,Constantinou AI,Stacewicz-Sapuntzakis M,Bowen PE,van Breemen RB

更新日期：1999-10-01 00:00:00

abstract：:Rats were fed either a high alpha-linolenate diet or a high linoleate diet from weaning to 4 mon of age. Soybean oil was used as a control. Phospholipid compositions of erythrocytes from the three dietary groups were not significantly different. However, the difference in the alpha-linolenate (18:3n-3)/linoleate (18:2...

journal_title：Lipids

authors： Sakai K,Okuyama H,Kon K,Maeda N,Sekiya M,Shiga T,Reitz RC

更新日期：1990-12-01 00:00:00

abstract：:This study was undertaken to determine the effect of various lipid emulsions on the hepato-biliary system in rats. Rats were randomly divided into six groups and infused continuously for 48 hr with either long-chain triglycerides (LCT), medium-chain triglycerides (MCT) or a mixture of MCT and LCT. One group infused wi...

journal_title：Lipids

authors： Rubin M,Halpern Z,Livoff A,Wennberg A,Tietz A,Antebi E,Lichtenberg D

更新日期：1992-05-01 00:00:00

abstract：:We evaluated the effects of dietary lipid class (phospholipid vs. neutral lipid) and level of n-3 long-chain PUFA (LC-PUFA) on the growth, digestive enzymatic activity, and histological organization of the intestine and liver in European sea bass larvae. Fish were fed from the onset of exogenous feeding at 7 to 37 d p...

journal_title：Lipids

authors： Gisbert E,Villeneuve L,Zambonino-Infante JL,Quazuguel P,Cahu CL

更新日期：2005-06-01 00:00:00

abstract：:Leaf wax of oats (Kelsey variety) consists of hydrocarbons (5%), esters (10%), free alcohols (45%), free acids (2.5%), β-diketone (5.5%), hydroxy-β-diketones (2.5%), and unidentified (29%). Wax on leaf blades contains more free alcohols than wax on leaf sheaths, and wax on the flag leaf sheath contains more β-diketone...

journal_title：Lipids

authors： Tulloch AP,Hoffman LL

更新日期：1973-11-01 00:00:00

abstract：:Plasma and liver lipids were studied in male weanling rats fed diets containing moderate levels of fat (6% by weight) as sunflower oil (SF diet, rich in linoleic acid), salmon oil (SM diet, rich in long-chain n-3 fatty acids), or a blend of peanut and rapeseed oil (PR diet, rich in oleic acid). After nine weeks of fee...

journal_title：Lipids

authors： Frémont L,Gozzelino MT

更新日期：1996-08-01 00:00:00

abstract：:Phytophthora species are eukaryotic sterol auxotrophs that possess the ability to grow, albeit poorly, in the complete absence of sterols. Growth of Phytophthora is often improved substantially when an exogenous source of sterol is provided. Additionally, sterols may be required for sexual and asexual sporulation in P...

journal_title：Lipids

authors： Dotson WD,Tove SR,Parks LW

更新日期：2000-03-01 00:00:00

abstract：:Phosphatidylinositol (PtdIns) and phosphatidylinositol 4-phosphate (PtdIns4P) kinase activities in plasma membranes isolated from canine left ventricle were partially characterized, and their sensitivity to a number of intracellular variables was established. PtdIns and PtdIns4P kinase activities were estimated by the...

journal_title：Lipids

authors： Kasinathan C,Xu ZC,Kirchberger MA

更新日期：1989-09-01 00:00:00

abstract：:This study evaluated the effects of conjugated linoleic acids (CLA) on tissue fatty acid composition and ex vivo prostaglandin E2 (PGE2) production in rats given diets varying in n-6 and n-3 fatty acids. Four groups of rats were given a basal semipurified diet (AIN-93G) containing 70 g/kg of added fat for 42 d. The fa...

journal_title：Lipids

authors： Li Y,Watkins BA

更新日期：1998-04-01 00:00:00

abstract：:According to the model of "response to injury," the arterial endothelium is occasionally injured in hyperlipidemia, hypertension, diabetes mellitus and in other states known as risk factors. The ensuing inflammatory response is modulated by cytokines and growth factors, among them platelet-derived growth factor (PDGF)...

journal_title：Lipids

authors： von Schacky C,Baumann K,Angerer P

更新日期：2001-01-01 00:00:00

abstract：:The present study examined the effect of varying dietary linoleate intake (0.01, 0.24, 2.4, 24, 80 or 160 g/kg diet) for 24 weeks on the distribution of triacylglycerol (TG) molecular species in rat epididymal adipose tissue. Adipose TG fractions were purified by thin-layer chromatography and separated into different ...

journal_title：Lipids

authors： Huang YS,Lin X,Smith RS,Redden PR,Jenkins DK,Horrobin DF

更新日期：1992-09-01 00:00:00