Effects of high alpha-linolenate and linoleate diets on erythrocyte deformability and hematological indices in rats.

Abstract:

:Rats were fed either a high alpha-linolenate diet or a high linoleate diet from weaning to 4 mon of age. Soybean oil was used as a control. Phospholipid compositions of erythrocytes from the three dietary groups were not significantly different. However, the difference in the alpha-linolenate (18:3n-3)/linoleate (18:2n-6) ratio of the diets was reflected in the n-3/n-6 ratios of the 20 and 22 carbon highly unsaturated fatty acids except for docosahexaenoic acid (22:6n-3) in the phospholipids. Despite the significant differences in the fatty acid compositions of phospholipids, no measurable differences were detectable in erythrocyte deformability, whole blood viscosity and hematological indices of the three dietary groups. These results indicate that the beneficial effects of the high alpha-linolenate diet, as compared with the high linoleate diet, are exerted without significant changes in these parameters.

journal_name

Lipids

journal_title

Lipids

authors

Sakai K,Okuyama H,Kon K,Maeda N,Sekiya M,Shiga T,Reitz RC

doi

10.1007/BF02535899

subject

Has Abstract

pub_date

1990-12-01 00:00:00

pages

793-7

issue

12

eissn

0024-4201

issn

1558-9307

journal_volume

25

pub_type

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