Abstract:
:Using an experimental model that enables the effects of alcohol to be distinguished from the effects of the nonalcoholic components present in wine, we determined whether wine has effects other than those of alcohol on the metabolism of cholesterol. Male rats were fed a standard diet and had free access to water and either wine or an equivalent alcohol solution for 45 d or 6 mon. Alcohol intake was similar in the two groups of animals. Consumption of the alcohol solution or wine did not influence plasma cholesterol or high density lipoprotein-cholesterol. At 45 d, the consumption both of wine and of alcohol solution reduced low density lipoprotein (LDL)-cholesterol and very low density lipoprotein cholesterol. At 6 mon, only the rats that consumed wine had reduced LDL-cholesterol. After 45 d of consuming alcohol solution, total cholesterol in the aorta was significantly increased mainly as a result of the rise in free cholesterol. In the aorta, the effect of wine consumption was similar to the effect of alcohol solution consumption, although it was less intense. The only clear effect that could be ascribed to the nonalcoholic components in wine was that the LDL-cholesterol was reduced in the long term, although aortic cholesterol was not.
journal_name
Lipidsjournal_title
Lipidsauthors
Cascón E,Roig R,Ardèvol A,Salvadó MJ,Arola L,Bladé Cdoi
10.1007/s11745-001-0732-6subject
Has Abstractpub_date
2001-04-01 00:00:00pages
383-8issue
4eissn
0024-4201issn
1558-9307journal_volume
36pub_type
杂志文章相关文献
LIPIDS文献大全abstract::Neuronal membranes are highly enriched with docosahexaenoic acid (22:6n-3), and its content can be altered by ethanol consumption. We have previously reported that the 22:6n-3 status in membrane affects the biosynthesis of phosphatidylserine (PS), a phospholipid class which contains an exceptionally high proportion of...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/BF02664769
更新日期:2000-02-01 00:00:00
abstract::Leaf wax of oats (Kelsey variety) consists of hydrocarbons (5%), esters (10%), free alcohols (45%), free acids (2.5%), β-diketone (5.5%), hydroxy-β-diketones (2.5%), and unidentified (29%). Wax on leaf blades contains more free alcohols than wax on leaf sheaths, and wax on the flag leaf sheath contains more β-diketone...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/BF02533144
更新日期:1973-11-01 00:00:00
abstract::A group of Angus beef cattle was removed from temperate pastures and fed a very low beta-carotene cereal-based ration in a feedlot for over 300 d. Half the group was supplemented weekly with retinyl palmitate (at the rate of 60,000 IU vitamin A/100 live weight (LW)/day), sufficient to offset clinical vitamin A deficie...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/s11745-006-5107-5
更新日期:2006-04-01 00:00:00
abstract::Cholesterol and cholesteryl esters were separated according to their carbon number and number of double bonds by high performance reversed-phase chromatography (HPRC) using acetonitrile/chloroform/methanol (1:1:1, v/v) as a mobile phase. It was found that within the same equivalent carbon number (ECN) category, choles...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/BF02534908
更新日期:1981-08-01 00:00:00
abstract::A 24-hr pretreatment of cultured human fibroblasts with trifluoperazine induced a marked increase in incorporation of saturated (stearic, palmitic) and unsaturated (oleic, arachidonic) fatty acids into phospholipids (1.5- to 2-fold for 5.10(-5) M trifluoperazine). Concomitantly, incorporation into cholesteryl esters w...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/BF02535513
更新日期:1988-05-01 00:00:00
abstract::To address the role of cell membrane neutral sphingomyelinase (EC 3.1.4.12; SMase) in the regulation of cholesterol metabolism in the liver parenchymal cell, we examined the effect of exogenous neutral SMase on the metabolism of cholesteryl esters and the secretion of VLDL and biliary lipids in isolated rat hepatocyte...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/s11745-003-1031-y
更新日期:2003-01-01 00:00:00
abstract::Saccharomyces cerevisiae cells were demonstrated to contain lysophosphatidylcholine (lysoPtdCho) acyltransferase (E.C. 2.3.1.23) activity. The enzyme displayed Km(app) of 69 microM for lysoPtdCho and 152 microM for oleoyl CoA. Enzyme activity was not affected by the addition of 1 mM Mg2+, Mn2+, Ca2+, or 200 mM EDTA. H...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/s11745-998-0328-1
更新日期:1998-12-01 00:00:00
abstract::Commercial fish oils and foods containing fish may contain trans and/or isomerized fatty acids (FA) produced during processing or as part of prepared foods. The current American Oil Chemists' Society (AOCS) official method for marine oils (method Ce 1i-07) is based on separation by use of poly(ethylene glycol) (PEG) c...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/s11745-011-3645-y
更新日期:2012-03-01 00:00:00
abstract::A method is described for the separation, identification, and quantitative estimation of the individual molecular species occurring in natural lecithin mixtures. Purified lecithin preparations are converted into diglyceride acetates by enzymic dephosphorylation and acetylation. The diglyceride acetates are separated o...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/BF02532559
更新日期:1967-05-01 00:00:00
abstract::The cholesterol-suppressive action of the tocotrienol-rich-fraction (TRF) of palm oil may be due to the effect of its constituent tocotrienols on beta-hydroxy-beta-methylglutaryl coenzyme A (HMG-CoA) reductase activity. The tocotrienols, modulate HMG-CoA reductase activity via a post-transcriptional mechanism. As a co...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/s11745-006-5119-1
更新日期:2006-05-01 00:00:00
abstract::Synthetic activators of peroxisome proliferator-activated receptors (PPAR)-alpha and -gamma are capable of reducing macrophage foam cell cholesterol accumulation through the activation of genes involved in cholesterol homeostasis. Since conjugated linoleic acids (CLA) were also demonstrated to activate PPARalpha and P...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/s11745-008-3226-x
更新日期:2008-10-01 00:00:00
abstract::Cholesterol biosynthesis from acetate-2-(14)C by the livers of suckling rats, which is known to be relatively slow, was increased 2-3-fold within 24 hours after severing the bile duct. Cholesterol synthesis by sham-operated litter mates showed no change under similar treatment. Mevalonate biosynthesis from acetate-2-(...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/BF02530913
更新日期:1967-03-01 00:00:00
abstract::In the present study we evaluated the uptake of ALA and its conversion to EPA + DHA in rats given linseed oil (LSO) in native form or as a microemulsion in whey protein or in lipoid. In a single oral dose study in which rats maintained on rodent pellets deficient in ω-3 fatty acids were intubated with 0.35 g LSO in li...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/s11745-013-3873-4
更新日期:2014-03-01 00:00:00
abstract::The source of free fatty acids (FFA) and the pathways contributing to the accumulation of neutral fats in livers of rats fed a cholesterol-enriched diet were investigated in this report. Supplementation with 1% cholesterol in the diet for four weeks resulted in hepatomegaly in the rats. The contents of cholesterol and...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/BF02537027
更新日期:1995-06-01 00:00:00
abstract::Because of the known advantages of coupling high performance liquid chromatography with mass spectrometry (HPLC-MS) in biological fluids, studies on the reversed-phase HPLC-MS system for direct analysis of conjugated bile acids in human bile samples are described. Ten samples of gallbladder bile of apparently healthy ...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/BF02534697
更新日期:1983-01-01 00:00:00
abstract::The aim of the present study was to identify the effects of dehydroepiandrosterone (DHEA) on hepatic lipid metabolism parameters and lipogenic gene mRNA expression in broiler chickens. A total of 72 1-day-old broiler chicks received a common basal diet with DHEA added at either 0 (control), 5 or 20 mg/kg feed. In the ...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/s11745-007-3104-y
更新日期:2007-11-01 00:00:00
abstract::The uptake of lipid from the yolk by the yolk sac membrane of the chick embryo is accompanied by the rapid esterification of a large proportion of the yolk cholesterol. This could arise from enhanced acyl-CoA:cholesterol acyltransferase (ACAT) activity and/or inhibition of cholesteryl ester hydrolase (CEH) activity. T...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/BF02536056
更新日期:1993-07-01 00:00:00
abstract::9-Hydroxy-2E-decenoic acid (9-HDA) is a precursor of the queen-produced substance, 9-oxo-2E-decenoic acid (9-ODA), which has various important functions and roles for caste maintenance in honeybee colonies (Apis mellifera). 9-HDA in royal jelly is considered to be a metabolite of 9-ODA produced by worker bees, and it ...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/s11745-010-3497-x
更新日期:2011-03-01 00:00:00
abstract::A method is described for the determination of the positions and geometric configurations of double bonds in polyunsaturated fatty acids. The procedure consists of three steps: 1) Partial reduction of the double bonds with hydrazine under conditions which give high yields of monoenes. 2) Isolation of thecis- and thetr...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/BF02532998
更新日期:1966-03-01 00:00:00
abstract::The contractions of three different regions of rat colon in response to platelet-activating factor (PAF) were compared. The ascending colon was found to be the most responsive. The slow contraction of the ascending colon induced by PAF was dependent on external Ca2+. CV-3988, a structural analog of PAF, slowly induced...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/BF02536563
更新日期:1991-12-01 00:00:00
abstract::Oxidized LDL (oxLDL) has been shown to activate the sphingomyelinase pathway producing ceramide in vascular smooth muscle cells. Therefore ceramide, which is a biologically active lipid causing apoptosis in a variety of cells, may be involved in the apoptotic action of oxLDL. In this study, we examined whether cholest...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/s11745-007-3067-z
更新日期:2007-10-01 00:00:00
abstract::Mitochondrial cytochrome P450 enzymes (CYP or P450, EC 1.14.13.15) play an important role in metabolism of cholesterol. CYP27A1 hydroxylates cholesterol at position 27 and, thus, initiates cholesterol removal from many extrahepatic tissues. CYP11A1 is a steroidogenic P450 that converts cholesterol to pregnenolone, the...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/s11745-008-3234-x
更新日期:2008-12-01 00:00:00
abstract::This report deals with the fluorometric determination of fatty alcohols generated by the reduction of the ester linkage of lipids with NaBH4, and with the limitations of the reduction method for assaying oxidized lipids. Optimum conditions for the fluorometric analysis of primary and secondary alcohols using 1-anthroy...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/BF02537169
更新日期:1990-09-01 00:00:00
abstract::A procedure for the preparation of specific molecular species of D-erythro-lactosylceramide involving deacylation and reacylation of lactosylceramide prepared from bovine brain gangliosides is described. Lactosylceramide was N-deacylated by alkaline hydrolysis and the resulting four lysolactosylceramides, which contai...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/BF02538917
更新日期:1994-10-01 00:00:00
abstract::The fatty acid (FA) profile of oysters generally reflects the dietary FA composition. Moreover, incorporation of FA into tissues is modulated by various metabolic factors, and final composition will depend upon the dietary sources, cumulative intake, and oysters' development stage. Thus, the aim of this study was to a...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1002/lipd.12177
更新日期:2019-09-01 00:00:00
abstract::The present study enumerates the synthesis, spectroscopic characterization, and evaluation of anticancer potential of esters of two n-9 fatty acids viz., oleic acid (OLA) and ricinoleic acid (RCA) with 2,4- or 2,6-diisopropylphenol. The synthesis strategy involved esterification of the hydroxyl group of diisopropylphe...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/s11745-012-3707-9
更新日期:2012-10-01 00:00:00
abstract::The effect of age and dietary fat type on tocopherol status was investigated using young and old C57BL/6Nia mice fed semipurified diets containing 5% (by weight) fish, corn or coconut oils and supplemented with 30, 100 or 500 ppm dl-alpha-tocopheryl acetate for 6 wk. Tocopherol levels in the diets, plasma, liver, kidn...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/BF02534004
更新日期:1987-05-01 00:00:00
abstract::Mycobacterium fortuitum utilizes certain stereoisometric mixtures of individual multimethyl branched alkanes as sole carbon source, including 2,6(R), 10(S), 14(RS)-tetramethylhexadecane; 2.6(R), 10(S), 14(RS)-tetramethylheptadecane; 2,6(RS), 10(RS)-trimethyltetradecane, and 2,6(R), 10(S)-trimethylpentadecane. Products...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/BF02532587
更新日期:1976-01-01 00:00:00
abstract::Cholesterol itself has very few structural/chemical features suitable for real-time imaging in living cells. Thus, the advent of dehydroergosterol [ergosta-5,7,9(11),22-tetraen-3beta-ol, DHE] the fluorescent sterol most structurally and functionally similar to cholesterol to date, has proven to be a major asset for re...
journal_title:Lipids
pub_type: 杂志文章,评审
doi:10.1007/s11745-008-3194-1
更新日期:2008-12-01 00:00:00
abstract::Many reports have shown the beneficial effects of consumption of pine seeds and pine seed oil. However, few studies have examined the biological effect of pinolenic acid (PNA; 5,9,12-18:3), the main fatty acid in pine seed oil. In this study, using murine macrophage RAW264.7 cells as a model, we examined the effect of...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/s11745-008-3276-0
更新日期:2009-03-01 00:00:00