Lysophosphatidylcholine acyltransferase activity in Saccharomyces cerevisiae: regulation by a high-affinity Zn2+ binding site.

abstract：:Rats were fed semipurified diets containing olive oil or partially hydrogenated corn oil at the 5 or 20% level for ca. 30 days. These fat diets contained the same amount of octadecenoate but differed in the geometry with respect to each fat level. Contents of t-18:1 were 26% and 41% of total fatty acids, respectively....

journal_title：Lipids

authors： Watanabe M,Cho YJ,Ide T,Sugano M

更新日期：1984-02-01 00:00:00

abstract：:The purpose of the present investigation was to test whether permanent skeletal muscle cells (rat L6 cells) could serve as an in vitro model for alpha-tocopherol (alphaTocH) biodiscrimination studies. L6 cells were incubated in the presence of high density lipoprotein (HDL), low density lipoprotein (LDL), and very low...

journal_title：Lipids

authors： Nakamura T,Reicher H,Sattler W

更新日期：1998-10-01 00:00:00

abstract：:Male and female weanling rats that were born to dams fed a diet low in linolenic acid received diets of 15% lipids by weight containing 45% elaidic acid (as trielaidin) and 8.5% or 0.1% linolenic acid for 10 weeks. Four other groups, in which palmitic or oleic acid replaced elaidic acid in the diet, served as controls...

journal_title：Lipids

authors： Astorg PO,Chevalier J

更新日期：1987-12-01 00:00:00

abstract：:Fatty acid compositions of polar lipids and triacylglycerols isolated from eggs of the sea urchin, Arbacia punctulata, were examined before and 15 min after insemination. The main fatty acids present in polar lipids and triacylglycerols were palmitate, palmitoleate, eicosaenoate, arachidonate and eicosapentaenoate, wh...

journal_title：Lipids

authors： Metzman MS,Mastroianni A,Strauss JF

更新日期：1978-11-01 00:00:00

abstract：:A 10-hydroxy stearic acid-containing lipid from Cryptosporidium parvum was purified by thin-layer chromatography and analyzed by infrared spectroscopy, fast-atom bombardment mass spectrometry, 1H and 31P nuclear magnetic resonance spectroscopy, and was identified as phosphatidyl-ethanolamine. ...

journal_title：Lipids

authors： Schrum DP,Alugupalli S,Kelly ST,White DC,Fayer R

更新日期：1997-07-01 00:00:00

abstract：:The aim of the present study was to identify the effects of dehydroepiandrosterone (DHEA) on hepatic lipid metabolism parameters and lipogenic gene mRNA expression in broiler chickens. A total of 72 1-day-old broiler chicks received a common basal diet with DHEA added at either 0 (control), 5 or 20 mg/kg feed. In the ...

journal_title：Lipids

authors： Tang X,Ma H,Zou S,Chen W

更新日期：2007-11-01 00:00:00

abstract：:After two months feeding either an (n-3) or an (n-6) fatty acid-rich diet, two groups of trout were switched to the (n-6) or the (n-3) fatty acid-rich diet, respectively. Half of each group was treated with 0.03% 5,8,11,14-eicosatetraynoic acid (ETYA) in the diet. Liver and intestinal brush border membrane lipids were...

journal_title：Lipids

authors： Pelletier X,Leray C

更新日期：1987-12-01 00:00:00

abstract：:Commercial fish oils and foods containing fish may contain trans and/or isomerized fatty acids (FA) produced during processing or as part of prepared foods. The current American Oil Chemists' Society (AOCS) official method for marine oils (method Ce 1i-07) is based on separation by use of poly(ethylene glycol) (PEG) c...

journal_title：Lipids

authors： Santercole V,Delmonte P,Kramer JK

更新日期：2012-03-01 00:00:00

abstract：:The conversion of labeled palmitic, linoleic, arachidonic and docosahexaenoic acids to their respective acyl CoA's was studied in homogenates and microsomes of rat tissues. The highest activity, both in homogenates and microsomes, was seen in liver and heart. There was moderate activity in retina, brain, lung, kidney ...

journal_title：Lipids

authors： Reddy TS,Bazan NG

更新日期：1984-12-01 00:00:00

abstract：:Chloroquine is shown to be a potent inhibitor of cholesterol biosynthesis by isolated rat hepatocytes. Half-maximal inhibition of cholesterogenesis occurs at ca. 10 micro M chloroquine. Chloroquine does not affect fatty acid synthesis by isolated hepatocytes. This suggests that chloroquine acts on the cholesterol bios...

journal_title：Lipids

authors： Beynen AC,van der Molen AJ,Geelen MJ

更新日期：1981-06-01 00:00:00

abstract：:The synthesis of phosphoglycerides is reviewed. Emphasis is placed upon precursor and intermediate compounds, phosphatidic acid, phosphatidyl choline, phosphatidyl ethanolamine, phosphatidyl serine, monoacylphosphoglycerides, purification and proof of structure. Suggestions are made for large scale synthesis of phosph...

journal_title：Lipids

authors： Jensen RG,Gordon DT

更新日期：1972-09-01 00:00:00

abstract：:Although migrating birds use stored triacylglycerol as their primary fuel for flight, they must retain sufficient stores of omega 6 and omega 3 fatty acids to sustain reproduction after the spring migration. Hepatic monoacylglycerol:acyl-coenzyme A acyltransferase (EC 2.3.1.22) (MGAT) activity is associated with physi...

journal_title：Lipids

authors： Mostafa N,Bhat BG,Coleman RA

更新日期：1994-11-01 00:00:00

abstract：:A group of Angus beef cattle was removed from temperate pastures and fed a very low beta-carotene cereal-based ration in a feedlot for over 300 d. Half the group was supplemented weekly with retinyl palmitate (at the rate of 60,000 IU vitamin A/100 live weight (LW)/day), sufficient to offset clinical vitamin A deficie...

journal_title：Lipids

authors： Siebert BD,Kruk ZA,Davis J,Pitchford WS,Harper GS,Bottema CD

更新日期：2006-04-01 00:00:00

abstract：:Liver fatty-acid-binding protein (FABP1, L-FABP) is the major cytosolic binding/chaperone protein for both precursor arachidonic acid (ARA) and the endocannabinoid (EC) products N-arachidonoylethanolamine (AEA) and 2-arachidonoylglycerol (2-AG). Although FABP1 regulates hepatic uptake and metabolism of ARA, almost not...

journal_title：Lipids

authors： McIntosh AL,Huang H,Landrock D,Martin GG,Li S,Kier AB,Schroeder F

更新日期：2018-06-01 00:00:00

abstract：:The effects of increasing concentrations of eicosapentaenoic acid (20:5n-3; EPA) and oleic acid (18:1n-9; OA) on esterification to triacylglycerols (TG) and phospholipids (PL), and the relationship to formation and secretion of the very low density lipoproteins (VLDL) were compared in the isolated perfused rat liver. ...

journal_title：Lipids

authors： Zhang ZJ,Wilcox HG,Castellani L,Fungwe TV,Elam MB,Heimberg M

更新日期：1993-05-01 00:00:00

abstract：:Normal phase high performance liquid chromatography methods are described for the separation of neutral lipid, fatty acid and five phospholipid classes using spectrophotometric detection at 206 nm. Separations were accomplished in less than 10 min for each lipid class. A mobile phase consisting of hexane/methyltertiar...

journal_title：Lipids

authors： Hamilton JG,Comai K

更新日期：1988-12-01 00:00:00

abstract：:(8R)-Hydroperoxy-(9Z,12Z)-octadecadienoic acid (8-HPODE) is formed by aspergilli as an intermediate in biosynthesis of oxylipins with effects on sporulation. 8-HPODE is transformed by separate diol synthases to (5S,8R)-dihydroxy- and (8R,11S)-dihydroxy-(9Z,12Z)-octadecadienoic acids (5,8- and 8,11-DiHODE). The former ...

journal_title：Lipids

authors： Jernerén F,Oliw EH

更新日期：2012-07-01 00:00:00

abstract：:Steroids bearing ketone functionality at carbon-7 are found commonly in nature, and the most prevalent of these are the 7-keto-delta5-sterols. These substances have diverse biological properties and are present in biological samples and food products. For the purpose of studying this class of oxysterols, many chemical...

journal_title：Lipids

authors： Parish EJ,Kizito SA,Qiu Z

更新日期：2004-08-01 00:00:00

abstract：:The effect of hydroperoxy and hydroxy derivatives of various fatty acids on human platelet aggregation was determined to delineate potencies and structure-activity function. In this regard, the 22-carbon n-3 fatty acids are the most potent inhibitors in comparison to the n-6 lipoxygenase derivatives. Submicromolar lev...

journal_title：Lipids

authors： Karanian JW,Kim HY,Salem N Jr

更新日期：1996-03-01 00:00:00

abstract：:The initial steps in the autoxidation of CLA methyl ester are poorly understood. The aim of this study was to determine the stereochemistry of the hydroperoxides formed during autoxidation of CLA methyl ester in the presence of a good hydrogen atom donor. For this purpose, 9-cis,11-trans CLA methyl ester was autoxidiz...

journal_title：Lipids

authors： Hämäläinen TI,Sundberg S,Hase T,Hopia A

更新日期：2002-06-01 00:00:00

abstract：:The gut microbiota is proposed as a "metabolic organ" involved in energy utilization and is associated with obesity. Dietary intervention is one of the approaches for obesity management. Changes in dietary components have significant impacts on host metabolism and gut microbiota. In the present study, we examined the ...

journal_title：Lipids

authors： Shang Y,Khafipour E,Derakhshani H,Sarna LK,Woo CW,Siow YL,O K

更新日期：2017-06-01 00:00:00

abstract：:We evaluated whether CETP and LCAT gene polymorphisms are statistically associated with the high-density lipoprotein (HDL) size distribution, the cholesterol level of HDL subclasses, and the acute coronary syndrome (ACS) susceptibility. Two CETP gene polymorphisms (rs4783961 and rs708272) and one LCAT polymorphism (rs...

journal_title：Lipids

authors： Vargas-Alarcon G,Perez-Mendez O,Herrera-Maya G,Garcia-Sanchez C,Martinez-Rios MA,Peña-Duque MA,Posadas-Sanchez R,Posadas-Romero C,Escobedo G,Fragoso JM

更新日期：2018-02-01 00:00:00

abstract：:Hepatocytes isolated from rainbow trout fed on diets containing either fish oil or olive oil were incubated with individual odd-chain length unsaturated fatty acids (19:1n-9, 19:2n-6, 19:3n-3, 21:2n-6, 21:3n-6, 21:4n-6, 21:3n-3, and 21:5n-3) to examine whether these fatty acids were substrates for modification by desa...

journal_title：Lipids

authors： Rodríguez C,Henderson RJ,Porter AE,Dick JR

更新日期：1997-06-01 00:00:00

abstract：:A ubiquitously expressed member of the cytochrome P450 superfamily, CYP51, encodes lanosterol 14alpha-demethylase, the first step in the conversion of lanosterol into cholesterol in mammals. The biosynthetic intermediates of lanosterol 14alpha-demethylation are oxysterols, which inhibit HMG-CoA reductase and sterol sy...

journal_title：Lipids

authors： Gibbons GF

更新日期：2002-12-01 00:00:00

abstract：:This study investigated a possible role for the epidermal growth factor (EGF) receptor protein tyrosine kinase in phosphoinositide metabolism with plasma membrane vesicles from human epidermoid carcinoma (A431) cells. We found a novel chloroform-soluble product radiolabeled with [gamma-32P]ATP that did not migrate fro...

journal_title：Lipids

authors： Brautigan DL,Randazzo P,Shriner C,Fain JN

更新日期：1985-07-01 00:00:00

abstract：:The present studies tested the hypothesis that some effects of tumor necrosis factor-alpha (TNF-alpha) are mediated by activation of sphingomyelinases and the production of ceramides. Differentiated 3T3-L1 adipocytes were incubated with short-chain ceramide analogs, (C2- and C6-ceramides: N-acetyl- and N-hexanoyl-sphi...

journal_title：Lipids

authors： Brindley DN,Wang CN,Mei J,Xu J,Hanna AN

更新日期：1999-01-01 00:00:00

abstract：:The levels of long-chain acyl-CoA in the livers of rats given diets containing various amounts of dietary oils were investigated. Increasing the amount of soybean oil in the diet from 5% to 25% (w/w) led to a 40% increase in long-chain acyl-CoA. With partially hydrogenated marine oil, a sigmoidal dose-response curve w...

journal_title：Lipids

authors： Nilsson A,Thomassen MS,Christiansen E

更新日期：1984-03-01 00:00:00

abstract：:In offspring exposed in utero to a maternal diet high in fat (HF), we have previously demonstrated that despite similar birth weights, HF adult offspring at 6 months of age had significantly higher body weights, greater adiposity, and increased triacylglycerol (TAG) levels as compared to controls. We hypothesized that...

journal_title：Lipids

authors： Seet EL,Yee JK,Jellyman JK,Han G,Ross MG,Desai M

更新日期：2015-06-01 00:00:00

abstract：:Linoleic acid was efficiently converted into the two major components of conjugated linoleic acid, 9Z,11E-octadecadienoic (1a) and 10E,12Z-octadecadienoic acid (1b) using either the superbase (n-butyllithium/potassium tert-butoxide) or by simply refluxing with KOH in 1-butanol. In turn, 1a and 1b were separated from e...

journal_title：Lipids

authors： Chen CA,Lu W,Sih CJ

更新日期：1999-08-01 00:00:00

abstract：:Inflammatory disorders are associated with a decrease in iron absorption because of the blockade of iron in storage organs. Fish oils, rich in n-3 PUFA, are used to prevent and treat inflammatory disorders and increase iron absorption in noninflamed rats. Here we examine whether n-3 PUFA prevent inflammation-related h...

journal_title：Lipids

authors： Rodríguez MC,Sáiz MP,Mitjavila MT

更新日期：2003-08-01 00:00:00