Impact of Fabp1 Gene Ablation on Uptake and Degradation of Endocannabinoids in Mouse Hepatocytes.

abstract：:The effects of growth temperature on the fatty acid compositions of the phosphatidylcholine (PC), phosphatidylethanolamine (PE), and total lipid (TL) fractions of the free-living nematode Caenorhabditis elegans were investigated. A reduction in growth temperature from 25 to 15 degrees C caused the proportions of eicos...

journal_title：Lipids

authors： Tanaka T,Ikita K,Ashida T,Motoyama Y,Yamaguchi Y,Satouchi K

更新日期：1996-11-01 00:00:00

abstract：:The effect of phosphatidylserine and sterol carrier proteins on cholesterol exchange was determined using an assay not requiring separation of donor and acceptor membrane vesicles. Sterol carrier protein-2 (SCP2, also called nonspecific lipid transfer protein), but not fatty acid binding protein (FABP, also called ste...

journal_title：Lipids

authors： Schroeder F,Butko P,Hapala I,Scallen TJ

更新日期：1990-11-01 00:00:00

abstract：:Dietary fatty acids have different effects on fat deposition in pigs. To clarify the underlying mechanisms of this difference, we compared the metabolism of palmitic (PAM, saturated), oleic (OLA, monounsaturated) and linoleic acid (LNA, polyunsaturated) in porcine adipocytes treated with 100 μM PAM, OLA or LNA. We obs...

journal_title：Lipids

authors： Yu C,Xi L,Chen J,Jiang Q,Yi H,Wang Y,Wang X

更新日期：2017-11-01 00:00:00

abstract：:Pycnogenol (PYC), an extract of French maritime pine bark (Pinus pinaster), is a potent antioxidant with potential health benefits. Its bioavailabilty has previously been shown by urinary excretion studies of constituents and metabolites of PYC. The aim of this study was to test the effect of PYC supplementation on me...

journal_title：Lipids

authors： Devaraj S,Vega-López S,Kaul N,Schönlau F,Rohdewald P,Jialal I

更新日期：2002-10-01 00:00:00

abstract：:The enzyme(s) present in acetonedried powder of rat and rabbit aortas, which catalyzes the synthesis and hydrolysis of cholesteryl ester, was purified partially by acid precipitation, acetone fractionation, O-(diethylaminoethyl) cellulose chromatography, and Sephadex G-100 filtration. The synthetic activity was purifi...

journal_title：Lipids

authors： Kothari HV

更新日期：1975-06-01 00:00:00

abstract：:Experimental studies have suggested an important role of the spleen in lipid metabolism, although with controversial results. Our purpose was to analyze the effect of a nutritionally balanced (NB) diet and a diet containing pork fat (PF) as source of lipids on the lipid profile of rats submitted to splenic surgery. Si...

journal_title：Lipids

authors： Dinis AP,Marques RG,Simões FC,Diestel CF,Caetano CE,Secchin DJ,Neto JF,Portela MC

更新日期：2009-06-01 00:00:00

abstract：:Stearoyl-CoA desaturase (SCD) is a regulatory enzyme in lipogenesis, catalyzing the rate-limiting step in the overall de novo synthesis of monounsaturated FA, mainly oleate and palmitoleate from stearoyl- and palmitoyl-CoA, respectively. Oleate and palmitoleate are the major monounsaturated FA of membrane phospholipid...

journal_title：Lipids

authors： Ntambi JM,Miyazaki M,Dobrzyn A

更新日期：2004-11-01 00:00:00

abstract：:The accumulation of (1-palmitoyl)lysophosphatidylcholine, lysolecithin, in gallbladder bile was observed during the first week of cholesterol-induced experimental cholelithiasis using the prairie dog model for cholesterol gallstone formation. Gallbladder fluid transport function decreased as bile lysolecithin concentr...

journal_title：Lipids

authors： Rutledge FA 2nd,Hickman DM,Dunn JJ,Frey CF,Matson RS

更新日期：1981-10-01 00:00:00

abstract：:Plant diseases caused by Phytophthora species are serious threats to agriculture and the natural environment. Genome sequencing has revealed the lack of a gene for canonical phospholipase C (PLC), an enzyme that was hitherto thought to be ubiquitous in eukaryotes. PLC acts in the hydrolysis of phosphatidylinositol 4,5...

journal_title：Lipids

authors： Howard JM,Beech PL,Callahan DL

更新日期：2018-08-01 00:00:00

abstract：:Analysis of cheek cell lipids has been suggested as a noninvasive method for monitoring the fatty acid composition of diets in humans. In a pilot study conducted to determine the validity of the method, cheek cell samples were collected from subjects consuming a low fat (20% of calories) diet consisting of fatty acids...

journal_title：Lipids

authors： Sampugna J,Light L,Enig MG,Jones DY,Judd JT,Lanza E

更新日期：1988-02-01 00:00:00

abstract：:Using primary rat hepatocyte cultures, the potency of several garlic-derived organosulfur compounds to inhibit cholesterol biosynthesis in toto as well as at early and late steps of this metabolic pathway was compared. Concerning early steps, allicin significantly inhibited incorporation of [14C]acetate into nonsaponi...

journal_title：Lipids

authors： Gebhardt R,Beck H

更新日期：1996-12-01 00:00:00

abstract：:Naturally occurring tetraalkylsubstituted furan fatty acids (F-acids) were tested as potential substrates for soybean lipoxygenase-1. For this purpose, F-acid methyl ester and phosphatidylcholines containing F-acids at the sn-2 position of the glycerol residue were incubated with the enzyme. Oxidation of F-acids only ...

journal_title：Lipids

authors： Batna A,Spiteller G

更新日期：1994-06-01 00:00:00

abstract：:The tissue distribution of newly synthesized 22:6n-3 and intermediate PUFA was examined in rainbow trout to further our understanding of the metabolism of this EFA in fish. Rainbow trout were fed a pulse of deuterated linolenic acid (D5-17,17,18,18,18-18:3n-3), and the tissue distribution of deuterated anabolites was ...

journal_title：Lipids

authors： Bell MV,Dick JR,Porter AE

更新日期：2003-09-01 00:00:00

abstract：:Oxidized lipoprotein(a) (oxLp(a)) is a more potent marker of atherogenesis than native Lp(a). However, the molecular mechanisms of oxLp(a) activity are not clear. Reactive oxygen species (ROS) have recently been suggested as acting as intracellular second messengers. In this study, the effects of oxLp(a) on endothelia...

journal_title：Lipids

authors： Wei DH,Zhang XL,Wang R,Zeng JF,Zhang K,Yang J,Li S,Lin XL,Jiang ZS,Wang GX,Wang Z

更新日期：2013-06-01 00:00:00

abstract：:(8R)-Hydroperoxy-(9Z,12Z)-octadecadienoic acid (8-HPODE) is formed by aspergilli as an intermediate in biosynthesis of oxylipins with effects on sporulation. 8-HPODE is transformed by separate diol synthases to (5S,8R)-dihydroxy- and (8R,11S)-dihydroxy-(9Z,12Z)-octadecadienoic acids (5,8- and 8,11-DiHODE). The former ...

journal_title：Lipids

authors： Jernerén F,Oliw EH

更新日期：2012-07-01 00:00:00

abstract：:Plasma and liver lipids were studied in male weanling rats fed diets containing moderate levels of fat (6% by weight) as sunflower oil (SF diet, rich in linoleic acid), salmon oil (SM diet, rich in long-chain n-3 fatty acids), or a blend of peanut and rapeseed oil (PR diet, rich in oleic acid). After nine weeks of fee...

journal_title：Lipids

authors： Frémont L,Gozzelino MT

更新日期：1996-08-01 00:00:00

abstract：:The degradation of alpha-tocopherol and the formation of alpha-tocopherol and triacylglycerol oxidation products at high temperatures (150-250 degrees C) over a heating period (0-4 h) for a model system ranging between triolein and tripalmitin were modeled by use of an experimental design. The oxidation products of al...

journal_title：Lipids

authors： Verleyen T,Kamal-Eldin A,Dobarganes C,Verhe R,Dewettinck K,Huyghebaert A

更新日期：2001-07-01 00:00:00

abstract：:The total lipids, total neutral lipids, and total phospholipids from Aedes aegypti and aedes albopictus cells cultivated in vitro in a medium containing fetal calf serum were analyzed. The mosquito cells were harvested in the logarithmic and stationary phases of growth. The fatty acid profiles of the lipids showed dif...

journal_title：Lipids

authors： McMeans E,Yang TK,Anderson LE,Jenkin HM

更新日期：1975-02-01 00:00:00

abstract：:1-O-Hexadecyl-2-O-acetyl-sn-glycero-3-phosphocholine (platelet-activating factor, PAF) is known to stimulate platelet aggregation and serotonin release in concentrations ranging from 10(-10)-10(-5) M. Since a variety of synthetic PAF analogues are potent antineoplastic agents in vitro and in vivo, it was the aim of th...

journal_title：Lipids

authors： Söling U,Eibl H,Nagel GA,Unger C

更新日期：1987-11-01 00:00:00

abstract：:Trans FA (TFA) have at least one trans double bond and comprise several isomers and types, including many of the CLA (e.g., c9,t11-18:2 CLA). Some TFA may have adverse effects (e.g., cardiovascular disease), whereas some are thought to have beneficial effects (e.g., anticarcinogenicity). The presence of TFA in human t...

journal_title：Lipids

authors： Shahin AM,McGuire MK,Anderson N,Williams J,McGuire MA

更新日期：2006-02-01 00:00:00

abstract：:We studied the actions of oxysterols on fatty acid distribution and lipid synthesis in cultured bovine aortic smooth muscle cells. Cultures were labeled with [1-14C]arachidonate or [1-14C]oleate. During a 24-hr incubation, 25- or 22R-hydroxycholesterol enhanced the incorporation of label into triglycerides, concomitan...

journal_title：Lipids

authors： Seillan C

更新日期：1990-03-01 00:00:00

abstract：:Chemical ionization (CI) mass spectra of various natural and synthetic steroids have been studied using methane, isobutane, ammonia, trideuterioammonia and hydroxy anion as reagent gases. The CI spectra of steroids give simple and well characterized ions, which provide information about molicular weight as well as fun...

journal_title：Lipids

authors： Lin YY

更新日期：1980-09-01 00:00:00

abstract：:Carbohydrate response element binding protein (ChREBP) regulates insulin-independent de novo lipogenesis. Recently, a novel ChREBPβ isoform was identified. The purpose of the current study was to define the effect of dietary carbohydrates (CHO) and obesity on the transcriptional activity of ChREBP isoforms and their r...

journal_title：Lipids

authors： Stamatikos AD,da Silva RP,Lewis JT,Douglas DN,Kneteman NM,Jacobs RL,Paton CM

更新日期：2016-01-01 00:00:00

abstract：:The purpose of this study was to examine the influence of long-term feeding of dietary fat rich in either n-3 or n-6 fatty acids on the availability of arachidonic acid (20:4n-6) in major phospholipids of gastric mucosa in rats. Three groups of male Wistar rats were fed either a standard diet, a cod liver oil-enriched...

journal_title：Lipids

authors： Olafsson SO,Hallgrimsson J,Gudbjarnason S

更新日期：2000-06-01 00:00:00

abstract：:The objective of this study was to establish the impact of caloric restriction on high fat diet-induced alterations on regulators of skeletal muscle growth. We hypothesized that caloric restriction would reverse the negative effects of high fat diet-induced obesity on REDD1 and mTOR-related signaling. Following an ini...

journal_title：Lipids

authors： Dungan CM,Li J,Williamson DL

更新日期：2016-08-01 00:00:00

abstract：:Observational evidence suggests that in populations consuming low levels of n-3 highly unsaturated fatty acids, women have higher blood levels of docosahexaenoic acid (DHA; 22:3n-6) as compared with men. Increased conversion of alpha-linolenic acid (ALA; 18:3n-3) to DHA by females has been confirmed in fatty acid stab...

journal_title：Lipids

authors： Kitson AP,Stroud CK,Stark KD

更新日期：2010-03-01 00:00:00

abstract：:The resolution of a series of racemic 1-alkyl-3-trityl-rac-glycerols and 1-alkyl-2-benzyl-rac-glycerols into their enantiomers by high-performance liquid chromatography (HPLC) was investigated. Of the racemic glycerol derivatives studied, only three (1,2-0-isopropylidene-rac-glycerol, 1,2-0-isopropylidene-3-benzyl-rac...

journal_title：Lipids

authors： Foglia TA,Maeda K

更新日期：1991-09-01 00:00:00

abstract：:A fluorescent radiolabeled triacylglycerol has been synthesized by using a fluorescent fatty acid (pyrene decanoic acid) and a radiolabeled oleic acid. This analog of the natural substrate, 1(3)pyrene decanoic-2,3 (1,2)-dioleoyl-sn-glycerol, has been tested as substrate for determining lipoprotein lipase and hepatic t...

journal_title：Lipids

authors： Dousset N,Negre A,Salvayre R,Rogalle P,Dang QQ,Douste-Blazy L

更新日期：1988-06-01 00:00:00

abstract：:Chlorpromazine (CPZ), a major tranquilizer, was found to be a potent inhibitor of lecithin:cholesterol acyltransferase (LCAT, EC 2.3.1.43) in the plasma of normal man, rat, rabbit and dog in vitro. The inhibitory effect of CPZ reached 35-50% at 0.5 mM depending on species; dog plasma LCAT appeared to be somewhat more ...

journal_title：Lipids

authors： Bell FP,Hubert EV

更新日期：1981-11-01 00:00:00

abstract：:The pyrrolidide and picolinyl ester derivatives of the fatty acids in two natural lipid samples rich in unsaturated fatty acids, pig testis lipids and cod liver oil were satisfactorily resolved on capillary columns of fused silica coated with stationary phases of varying polarity. The picolinyl esters, in particular, ...

journal_title：Lipids

authors： Christie WW,Brechany EY,Johnson SB,Holman RT

更新日期：1986-10-01 00:00:00