The fatty acid 8,11-diol synthase of Aspergillus fumigatus is inhibited by imidazole derivatives and unrelated to PpoB.

abstract：:The n-6 and n-3 fatty acid status of developing organs is the cumulative result of the diet lipid composition and many complex events of lipid metabolism. Little information is available, however, on the potential effects of the saturated fatty acid chain length (8:0-16:0) or oleic acid (18:1) content of the diet on t...

journal_title：Lipids

authors： Wall KM,Diersen-Schade D,Innis SM

更新日期：1992-12-01 00:00:00

abstract：:We have studied the effect of various diets on the phospholipid fatty acid composition and in vitro delta 5 desaturase activity of hepatic microsomes derived either from the normal or streptozotocin-induced diabetic rat. The diets studied were the standard rat chow diet and a basal fat-free diet supplemented either wi...

journal_title：Lipids

authors： Dang AQ,Kemp K,Faas FH,Carter WJ

更新日期：1989-10-01 00:00:00

abstract：:In plants, two pathways are utilized for the synthesis of isopentenyl diphosphate (IPP), the universal precursor for isoprenoid biosynthesis. In this paper we review findings and observations made primarily with tobacco BY-2 cells (TBY-2), which have proven to be an excellent system in which to study the two biosynthe...

journal_title：Lipids

authors： Hemmerlin A,Gerber E,Feldtrauer JF,Wentzinger L,Hartmann MA,Tritsch D,Hoeffler JF,Rohmer M,Bach TJ

更新日期：2004-08-01 00:00:00

abstract：:A protocol using a dry column method was modified for the extraction of total lipids and the simultaneous separation and quantitation of neutral and polar lipids in human milk. The triacylglycerol, cholesterol, phospholipid and vitamin E contents of the lipid extracts were determined and compared with lipids extracted...

journal_title：Lipids

authors： Collins SE,Jackson MB,Lammi-Keefe CJ,Jensen RG

更新日期：1989-08-01 00:00:00

abstract：:CLA has a range of biological properties, including effects on lipid metabolism and body composition in experimental animals. The prevalent isomer of CLA found in the human diet is 9c,11 t-CLA, and it is predominantly found in products containing fat from ruminant animals. This study investigated the effect of dietary...

journal_title：Lipids

authors： Hayman A,MacGibbon A,Pack RJ,Rutherfurd K,Green JH

更新日期：2002-07-01 00:00:00

abstract：:Starting at 21 days of age, groups of six rats each were fed a basal Torula yeast diet supplemented with 0.4% L-methionine and varying amounts of vitamin E as dl-alpha tocopherol acetate, selenium as sodium selenite, and with either 10% stripped corn oil, stripped lard, or coconut oil. By 7 wk, pentane production by r...

journal_title：Lipids

authors： Dillard CJ,Litov RE,Tappel AL

更新日期：1978-06-01 00:00:00

abstract：:The beneficial roles of dietary fish oil in lowering serum TAG levels in animals and humans have been attributed in part to the high content of two n-3 polyunsaturated very long-chain FA, EPA, and DHA. Recent studies show that EPA induces mitochondrial beta-oxidation in hepatocytes, which might contribute to the syste...

journal_title：Lipids

authors： Guo W,Xie W,Lei T,Hamilton JA

更新日期：2005-08-01 00:00:00

abstract：:This study was designed to determine the nutritional lipid requirement of Manchurian trout and to investigate the effects of lipid concentrations on the antioxidant status in larvae with experimental diets with different lipid levels. Oxidative stress differences between different organs and tissues were also assessed...

journal_title：Lipids

authors： Zhang H,Mu Z,Xu L,Xu G,Liu M,Shan A

更新日期：2009-07-01 00:00:00

abstract：:Fish easily accumulate n-3 PUFA of exogenous origin, but the underlying mechanisms are not well established in the whole animal. This study was undertaken to investigate whether this feature was physiologically associated with mitochondrial and peroxisomal capacities that differentially affect FA oxidation. For this p...

journal_title：Lipids

authors： Du ZY,Demizieux L,Degrace P,Gresti J,Moindrot B,Liu YJ,Tian LX,Cao JM,Clouet P

更新日期：2004-09-01 00:00:00

abstract：:A recent study on the metabolism of 1-14C-alpha-linolenic acid in the guinea pig revealed that the fur had the highest specific activity of all tissues examined, 48 h after dosing. The present study investigated the pattern of tissue lipid labeling following an oral dose of 1-14C-linoleic acid after the animals had be...

journal_title：Lipids

authors： Fu Z,Attar-Bashi NM,Sinclair AJ

更新日期：2001-03-01 00:00:00

abstract：:Decreased triacylglycerol synthesis within hepatocytes due to decreased diacylglycerol acyltransferase (DGAT) activity has been suggested to be an important mechanism by which diets rich in fish oil lower plasma triacylglycerol levels. New findings suggest that eicosapentaenoic acid (EPA), and not docosahexaenoic acid...

journal_title：Lipids

authors： Madsen L,Rustan AC,Vaagenes H,Berge K,Dyrøy E,Berge RK

更新日期：1999-09-01 00:00:00

abstract：:Male Wistar rats were fed semipurifed diets containing 20% fat for 25 weeks. Ten different oils or oil blends were employed, including rapessed oils, simulated rapeseed-type oils, and modified rapeseed-type oils. Safflower, soybean, and hydrogenated coconut oils served as control oils. Histopathological examination of...

journal_title：Lipids

authors： McCutcheon JS,Umermura T,Bhatnager MK,Walker BL

更新日期：1976-07-01 00:00:00

abstract：:The FA composition of Fasciola hepatica 12 kDA purified native FA-binding protein (nFh12), a candidate vaccine against fascioliasis, is described. The FA chain lengths ranged between 12 and 24 carbons. The principal FA were 16:0, 18:1n-9, 18:0, 20:4n-6, and 20:1n-9. The acids 16:0, 18:1n-9, and 18:0 comprised over hal...

journal_title：Lipids

authors： Carballeira NM,Cruz H,Hillyer GV

更新日期：2003-07-01 00:00:00

abstract：:9-Hydroxy-2E-decenoic acid (9-HDA) is a precursor of the queen-produced substance, 9-oxo-2E-decenoic acid (9-ODA), which has various important functions and roles for caste maintenance in honeybee colonies (Apis mellifera). 9-HDA in royal jelly is considered to be a metabolite of 9-ODA produced by worker bees, and it ...

journal_title：Lipids

authors： Kodai T,Nakatani T,Noda N

更新日期：2011-03-01 00:00:00

abstract：:Lipoprotein(a) [Lp(a)] represents a class of lipoprotein particles having as a protein moiety apoB-100 linked by a single disulfide bond to apolipoprotein(a) [apo(a)], a multikringle structure with a high degree of homology with plasminogen. A recognized feature of Lp(a) is its instability on storage caused by attenda...

journal_title：Lipids

authors： Scanu AM,Hinman J,Pfaffinger D,Edelstein C

更新日期：2004-06-01 00:00:00

abstract：:There have been a limited number of studies investigating surfactant lipid changes in lung with trace elements. The present investigation was designed to examine the effect of moderate zinc deficiency on the lipid metabolism in rat lung. We also evaluated whether zinc deficiency, which is a wide-spread problem, could ...

journal_title：Lipids

authors： Gomez NN,Ojeda MS,Gimenez MS

更新日期：2002-03-01 00:00:00

abstract：:We hypothesized that tumor-bearing (TB) nude mice, because they are reported to have no detectable, circulating tumor necrosis factor (TNF)/cachectin, would regulate their plasma free fatty acid (FFA) levels normally when fasted and refed. We compared levels of individual plasma FFA in response to fasting (24 hr) and ...

journal_title：Lipids

authors： Lin C,Blank W,Ceriani RL,Baker N

更新日期：1992-01-01 00:00:00

abstract：:Recent work in our lab has shown that the chemoprotective fatty acid, conjugated linoleic acid (CLA), inhibits phorbol ester skin tumor promotion in mice. Because little is known about the deposition of CLA into tissues as well as its biological activity, this study compared the incorporation and biological activity o...

journal_title：Lipids

authors： Liu KL,Belury MA

更新日期：1997-07-01 00:00:00

abstract：:A rat liver cytosolic cholesteryl ester hydrolase (CEH) was purified 12,600-fold by ammonium sulfate precipitation, cation exchange chromatography and gel permeation high-performance liquid chromatography, with an overall yield of 20%. Its properties are compared to those of pancreatic CEH, with which it has sometimes...

journal_title：Lipids

authors： Ghosh S,Grogan WM

更新日期：1991-10-01 00:00:00

abstract：:We examined the initial transport of a long-chain unsaturated fatty acid, linoleic acid, by brush border membrane vesicles isolated from rabbit small intestine. This preparation allowed us to examine the transport of linoleic acid across the brush border membrane without the effect of the unstirred water layer or cyto...

journal_title：Lipids

authors： Ling KY,Lee HY,Hollander D

更新日期：1989-01-01 00:00:00

abstract：:One of the main biological systems that can be used as a model for studying the molecular mechanisms involved in membrane fusion is the formation of the nuclear envelope (NE). NE assembly to form the male pronucleus at fertilization occurs by binding of NE membrane precursor vesicles to chromatin and their fusion. MV1...

journal_title：Lipids

authors： Larijani B,Dufourc EJ

更新日期：2006-10-01 00:00:00

abstract：:The reaction of alpha-tocopherol (alpha-T) with superoxide anion (O2-) in both dry acetonitrile and in aqueous acetonitrile solution is described. The O2- was generated by the electrochemical reduction of molecular oxygen in acetonitrile, using tetrabutylammonium bromide as an electrolyte. alpha-T was reacted with O2-...

journal_title：Lipids

authors： Csallany AS,Ha YL

更新日期：1992-03-01 00:00:00

abstract：:The effectiveness of different fatty acids as inhibitors of fatty acyl delta 5 desaturation activity in human skin fibroblasts has been investigated. When incubated with 2.25 microM [14C] eicosatrienoate (20:3 omega 6) in otherwise lipid-free medium, these cells rapidly incorporate the radiolabeled fatty acid into cel...

journal_title：Lipids

authors： Rosenthal MD,Doloresco MA

更新日期：1984-11-01 00:00:00

abstract：:In a search for a preferred source of gamma-linolenic (all-cis-6,9,12-octadecatrienoic) acid, seed oils of 33 species of Boraginaceae were examined. The desired triene was found primarily in the subfamily Boraginoideae in amounts ranging from 0.2 to 18%. Oils of this subfamily also contain 0.2 to 15% of the tetraene, ...

journal_title：Lipids

authors： Miller RW,Earle FR,Wolff IA,Barclay AS

更新日期：1968-01-01 00:00:00

abstract：:Glucose-sensitive liposomes were prepared by incorporating hydrophobically modified glucose oxidase (EC 1.1.3.4.) into the liposomal bilayer of dioleoylphosphatidylethanolamine and cholesteryl hemisuccinate. For the release test, calcein, a fluorescence marker, was entrapped in the liposomes. The liposomes were stable...

journal_title：Lipids

authors： Jo SM,Lee HY,Kim JC

更新日期：2008-10-01 00:00:00

abstract：:Hepatocytes isolated from rainbow trout fed on diets containing either fish oil or olive oil were incubated with individual odd-chain length unsaturated fatty acids (19:1n-9, 19:2n-6, 19:3n-3, 21:2n-6, 21:3n-6, 21:4n-6, 21:3n-3, and 21:5n-3) to examine whether these fatty acids were substrates for modification by desa...

journal_title：Lipids

authors： Rodríguez C,Henderson RJ,Porter AE,Dick JR

更新日期：1997-06-01 00:00:00

abstract：:A 10-hydroxy stearic acid-containing lipid from Cryptosporidium parvum was purified by thin-layer chromatography and analyzed by infrared spectroscopy, fast-atom bombardment mass spectrometry, 1H and 31P nuclear magnetic resonance spectroscopy, and was identified as phosphatidyl-ethanolamine. ...

journal_title：Lipids

authors： Schrum DP,Alugupalli S,Kelly ST,White DC,Fayer R

更新日期：1997-07-01 00:00:00

abstract：:Active lipases were isolated from the culture supernatant of the basidiomycetous fungus Pleurotus sapidus by foam fractionation. The pH value, the gas flow, and the foaming period were systematically varied to optimize the transport of the enzymes into the foam phase. On a 70-mL scale, a maximum recovery of hydrolytic...

journal_title：Lipids

authors： Linke D,Zorn H,Gerken B,Parlar H,Berger RG

更新日期：2005-03-01 00:00:00

abstract：:Salmon farmers are currently using high-energy feeds containing up to 35% fat; the fish's capability of fully utilizing these high-energy feeds has received little attention. Carnitine is an essential component in the process of mitochondrial fatty acid oxidation and, with the cooperation of two carnitine palmitoyltra...

journal_title：Lipids

authors： Frøyland L,Madsen L,Eckhoff KM,Lie O,Berge RK

更新日期：1998-09-01 00:00:00

abstract：:Diets that contain high levels of n-3 fatty acids from fish oil have been shown to significantly effect macrophage cytolytic capacity, tumor necrosis factor alpha production and eicosanoid production. The present study was undertaken to determine whether n-3 fatty acids from vegetable origin [linseed oil (LIN)] would ...

journal_title：Lipids

authors： Hubbard NE,Chapkin RS,Erickson KL

更新日期：1994-09-01 00:00:00