Abstract:
:Salmon farmers are currently using high-energy feeds containing up to 35% fat; the fish's capability of fully utilizing these high-energy feeds has received little attention. Carnitine is an essential component in the process of mitochondrial fatty acid oxidation and, with the cooperation of two carnitine palmitoyltransferases (CPT-I and CPT-II) and a carnitine acylcarnitine transporter across the inner mitochondrial membrane, acts as a carrier for acyl groups into the mitochondrial matrix where beta-oxidation occurs. However, no reports are available differentiating between CPT-I and CPT-II activities in fish. In order to investigate the potential for fatty acid catabolism, the activities of key enzymes involved in fatty acid oxidation were determined in different tissues from farmed Atlantic salmon (Salmo salar), i.e., acyl-CoA oxidase (ACO) and CPT-I and CPT-II. Malonyl-CoA was a potent inhibitor of CPT-I activity not only in red muscle but also in liver, white muscle, and heart. By expressing the enzyme activities per wet tissue, the CPT-I activity of white muscle equaled that of the red muscle, both being > liver. CPT-II dominated in red muscle whereas the liver and white muscle activities were comparable. ACO activity was high in the liver regardless of how the data were calculated. Based on the CPT-II activity and total palmitoyl-L-carnitine oxidation in white muscle, the white muscle might have a profound role in the overall fatty acid oxidation capacity in fish.
journal_name
Lipidsjournal_title
Lipidsauthors
Frøyland L,Madsen L,Eckhoff KM,Lie O,Berge RKdoi
10.1007/s11745-998-0289-4subject
Has Abstractpub_date
1998-09-01 00:00:00pages
923-30issue
9eissn
0024-4201issn
1558-9307journal_volume
33pub_type
杂志文章相关文献
LIPIDS文献大全abstract::Freshwater bryozoan Pectinatella magnifica was collected from a sand pit (South Bohemia). The total lipids after extraction from lyophilized bryozoans were analyzed using high-performance liquid chromatography/high-resolution negative tandem electrospray mass spectrometry. A total of 19 lipid classes were identified, ...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1002/lipd.12039
更新日期:2018-04-01 00:00:00
abstract::The diurnal variation in lysosomal acid cholesteryl ester hydrolase (Acid CEH), (EC 3.1.1.13) has been examined in fed, fasted and adrenalectomized rats. The Acid CEH activity of normal rat liver exhibits a diurnal rhythm with maxima at 06.00 hours and minima at 18.00 hours, but such a rhythm was not observed in splee...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/BF02534362
更新日期:1985-01-01 00:00:00
abstract::We studied the actions of oxysterols on fatty acid distribution and lipid synthesis in cultured bovine aortic smooth muscle cells. Cultures were labeled with [1-14C]arachidonate or [1-14C]oleate. During a 24-hr incubation, 25- or 22R-hydroxycholesterol enhanced the incorporation of label into triglycerides, concomitan...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/BF02544334
更新日期:1990-03-01 00:00:00
abstract::In the present study we evaluated the uptake of ALA and its conversion to EPA + DHA in rats given linseed oil (LSO) in native form or as a microemulsion in whey protein or in lipoid. In a single oral dose study in which rats maintained on rodent pellets deficient in ω-3 fatty acids were intubated with 0.35 g LSO in li...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/s11745-013-3873-4
更新日期:2014-03-01 00:00:00
abstract::Dietary lipids, in particular unsaturated fat, promote the development of many experimental tumors. However, no mechanisms to fully explain these effects have been elucidated. Recent reports, which we summarize here, suggest a role for gap junction-mediated intercellular communication in the process of tumor promotion...
journal_title:Lipids
pub_type: 杂志文章,评审
doi:10.1007/BF02537277
更新日期:1987-06-01 00:00:00
abstract::Soy isoflavones may impede atherogenic processes associated with cardiovascular disease. Research suggests that the postprandial generation of TG-rich remnants contributes to the development of atherosclerosis. The purpose of the current study was to determine if 39 g soy (85 mg aglycone isoflavones, treatment) compar...
journal_title:Lipids
pub_type: 临床试验,杂志文章
doi:10.1007/s11745-006-5095-5
更新日期:2006-03-01 00:00:00
abstract::The current state of knowledge concerning the absorption and transport of dietary fat with emphasis on long-chain polyunsaturated n-3 fatty acids in mammals is reviewed. It is apparent that long-chain polyunsaturated n-3 fatty acids, either as free acids or as part of triglycerides, are readily absorbed in the gut and...
journal_title:Lipids
pub_type: 杂志文章,评审
doi:10.1007/BF02535644
更新日期:1988-11-01 00:00:00
abstract::A simple method is described for the preparation of [6,7,7(-2)H3] sterols and steroids. The synthesis starts with a Δ(5)-sterol or steroid and involves preparation of the 6-oxo-3α,5α-cyclosteroid, base exchange in the presence of deuterium oxide to introduce two deuteriums at the C-7 position and sodium borodeuteride ...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/BF02534596
更新日期:1982-12-01 00:00:00
abstract::The acylation of lysophospholipids by rat liver acyltransferases was studied. A comparison between ester and ether lysophospholipids as substrates revealed large differences in substrate properties. For instance, oleic acid from oleoyl-CoA and arachidonic acid from arachidonoyl-CoA were not incorporated into 1-O-octad...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/BF02535535
更新日期:1987-11-01 00:00:00
abstract::Material dealing with the chemistry, biochemistry, and biological activities of oxysterols is reviewed for the period 1987-1995. Particular attention is paid to the presence of oxysterols in tissues and foods and to their physiological relevance. ...
journal_title:Lipids
pub_type: 杂志文章,评审
doi:10.1007/BF02522641
更新日期:1996-05-01 00:00:00
abstract::One of the main biological systems that can be used as a model for studying the molecular mechanisms involved in membrane fusion is the formation of the nuclear envelope (NE). NE assembly to form the male pronucleus at fertilization occurs by binding of NE membrane precursor vesicles to chromatin and their fusion. MV1...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/s11745-006-5045-2
更新日期:2006-10-01 00:00:00
abstract::Two novel lipopeptides, which have the peptide ligands [alpha-melanocyte stimulating hormone (alpha-MSH)] sequence and repeated [Gly-Arg-Gly-Asp-Se (GRGDS) sequence], are designed, synthesized by the solid-phase method, and introduced into liposome membranes by the freeze-thaw method. These liposomes bearing the pepti...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/s11745-000-0572-4
更新日期:2000-06-01 00:00:00
abstract::Membrane phospholipid (PL) composition has been shown to affect cellular function by altering membrane physical structure. The sarcolemma plasma membrane (SLpm) is integral to skeletal muscle function and health. Previous studies assessing SLpm PL composition have demonstrated contamination from transverse (t)-tubule,...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/s11745-013-3770-x
更新日期:2013-04-01 00:00:00
abstract::The effects of increasing concentrations of eicosapentaenoic acid (20:5n-3; EPA) and oleic acid (18:1n-9; OA) on esterification to triacylglycerols (TG) and phospholipids (PL), and the relationship to formation and secretion of the very low density lipoproteins (VLDL) were compared in the isolated perfused rat liver. ...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/BF02535940
更新日期:1993-05-01 00:00:00
abstract::The relationship between the biosynthesis of long-chain fatty acids and their distribution in the key organs of hypertension is of considerable interest because of their role in the production of vasoactive eicosanoids and their effects on membrane properties. The present study analyzed the fatty acid compositions of ...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/s11745-998-0272-0
更新日期:1998-08-01 00:00:00
abstract::The effects of droplet size and emulsifiers on oxidative stability of polyunsaturated TAG in oil-in-water (o/w) emulsions with droplet sizes of 0.806 +/- 0.0690, 3.28 +/- 0.0660, or 10.7 +/- 0.106 microm (mean +/- SD) were investigated. Hydroperoxide contents in the emulsion with a mean droplet size of 0.831 microm we...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/s11745-005-1410-4
更新日期:2005-05-01 00:00:00
abstract::This study examined the effects of five CLA isomers and the non-conjugated LA on nitric oxide (NO) production, an important modulator of vasodilation, inflammation, and cytotoxicity. Bovine aortic endothelial cells (BAECs) were pretreated with pure CLAs (c9, c11-, c9, t11-, t9, t11-, t10, c12-, c11, c13-CLA) and the n...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/s11745-008-3160-y
更新日期:2008-04-01 00:00:00
abstract::A one-carbon degradation of long-chain fatty acids, which was found to occur in the brains of rats in vivo, has been investigated in a brain microsomal fraction in vitro. Decarboxylation of the alpha-hydroxy acid, a possible intermediate product between the substrate and the next shorter acid, in the presence of brain...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/BF02531201
更新日期:1968-05-01 00:00:00
abstract::A specific radioimmunoassay for platelet-activating factor (PAF) sensitive in the range 10-1000 pg (0.02-2 pmoles) has been developed. Detailed quantitative hapten inhibition studies showed specificity for the acetyl group at C-2 of PAF, a requirement for the ether linkage at C-1 and some tolerance for substituents on...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/BF02536517
更新日期:1991-12-01 00:00:00
abstract::Strong perturbation of the ultraviolet spectrum of the tyrosines of porcine pancreatic colipase A is observed in the presence of Triton X-100 at concentration above the critical micellar concentration. Spectrophotometric titration of the phenolic groups of the protein shows that the apparent pKa value for two tyrosine...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/BF02534109
更新日期:1980-01-01 00:00:00
abstract::The effects of different dietary fats on ovine adipose tissue metabolism have been investigated. Six-month old sheep were fed for 6 weeks a control diet or diets supplemented with either tallow or a mixture of sunflower seed oil and soybean oil, treated to protect the fats from hydrolysis and hydrogenation in the rume...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/BF02532883
更新日期:1976-09-01 00:00:00
abstract::Guar gum has a well-recognized hypolipidemic effect. This effect is thought to be due to the physicochemical properties of guar gum, which may cause changes in adsorption of lipids or the viscosity of the intestinal contents. Guar gum is a non-specific absorption inhibitor of any type of lipid-soluble compound. Perman...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/s11745-011-3570-0
更新日期:2011-08-01 00:00:00
abstract::Meadowfoam oil is unusual because over 95% of the fatty acids are 20- and 22-carbon aliphatic acids with cis double bonds located principally at the 5- and/or 13-position. Since little information is available on the metabolism of the 5c-20:1 and 5c,13c-22:2 fatty acids, an exploratory study in mice was conducted to i...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/BF02535623
更新日期:1991-09-01 00:00:00
abstract::Oxidized low density lipoprotein (Ox-LDL) is a well-established risk factor in atherosclerosis and lysophosphatidylcholine (LysoPtdCho) is considered to be one of the major atherogenic component of Ox-LDL. The purpose of this work was to investigate the effects of two membrane n-3 long chain polyunsaturated fatty acid...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/s11745-009-3284-8
更新日期:2009-03-01 00:00:00
abstract::Trans FA (TFA) have at least one trans double bond and comprise several isomers and types, including many of the CLA (e.g., c9,t11-18:2 CLA). Some TFA may have adverse effects (e.g., cardiovascular disease), whereas some are thought to have beneficial effects (e.g., anticarcinogenicity). The presence of TFA in human t...
journal_title:Lipids
pub_type: 杂志文章,随机对照试验
doi:10.1007/s11745-006-5082-x
更新日期:2006-02-01 00:00:00
abstract::Maternal smoking during pregnancy has been associated with a reduced content of n-3 long-chain PUFA (LC-PUFA) in breast milk, thereby reducing the intake of key nutrients by the infants. We postulated that the mammary gland is affected by maternal smoking in the process of n-3 LC-PUFA secretion into milk. This prompte...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/s11745-004-1276-5
更新日期:2004-07-01 00:00:00
abstract::The degradation of alpha-tocopherol and the formation of alpha-tocopherol and triacylglycerol oxidation products at high temperatures (150-250 degrees C) over a heating period (0-4 h) for a model system ranging between triolein and tripalmitin were modeled by use of an experimental design. The oxidation products of al...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/s11745-001-0777-6
更新日期:2001-07-01 00:00:00
abstract::Acetate supplementation increases plasma acetate, brain acetyl-CoA, histone acetylation, phosphocreatine levels, and is anti-inflammatory in models of neuroinflammation and neuroborreliosis. Although radiolabeled acetate is incorporated into the cellular lipid pools, the effect that acetate supplementation has on lipi...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/s11745-014-3911-x
更新日期:2014-07-01 00:00:00
abstract::We describe a method for the quantitative analysis of molecular species of diacylglycerol and alkylacylglycerol as their diradylglycerobenzoate derivatives. Synthetic internal standards were used to provide quantitative determinations of the low levels of diacylglycerol and alkylacylglycerol and their individual molec...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/BF02544045
更新日期:1990-11-01 00:00:00
abstract::This study investigates the protective effect of N-stearoylethanolamine (NSE), a bioactive N-acylethanolamine , on the lipid profile distribution in the pancreas of obesity-induced insulin resistant (IR) rats fed with prolonged high fat diet (58% of fat for 6 months). The phospholipid composition was determined using ...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/s11745-014-3960-1
更新日期:2015-01-01 00:00:00